Clinical Digest: Recent Clinical Trials on Attention Deficit Hyperactivity Disorder (ADHD)
To assist researchers and healthcare practitioners in staying up-to-date with the latest advancements in clinical research, the Clinical Digest Team has compiled a comprehensive list of recent clinical trials related to Attention Deficit Hyperactivity Disorder (ADHD). These trials are organized by their release dates for your convenience. (Last updated on: 2025-05-02)
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TABLE 1: Clinical Digest: Recent Clinical Trials on Attention Deficit Hyperactivity Disorder (ADHD)
| Clinical Trial | Contact(s) | Date | |
|---|---|---|---|
| 1 | COmmunities Aligned to Reduce Concussion and Head Impact Exposure (COACH) PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: Head impacts in collision sports such as football are a public health concern, as repetitive head impacts, even if a concussion is not suspected, have negative effects on brain health. This study has partnered with a community stakeholder group to create a safety program for youth football named COmmunities Aligned to reduce Concussion and Head impact exposure (COACH), … |
JILLIAN URBAN; | 2025-05-01 |
| 2 | Scalp Acupuncture Treatment for Chronic Tic Disorders in Children: A Multicenter Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to learn if scalp acupuncture works to treat chronic tic disorders (CTD) in children. It will also learn about the safety of scalp acupuncture. The main questions it aims to answer are: * Does scalp acupuncture improve clinical symptoms and social functioning, … |
HAO ZHOU; | 2025-05-01 |
| 3 | Home-Based Executive Function Training Intervention For Attention-Deficit/ Hyperactivity Disorder-prone Children PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to investigate the effectiveness of a home-based executive function training Intervention on children’s ADHD symptoms, executive function and parents’ parenting stress. |
WUHAN MENTAL HEALTH CENTRE | 2025-05-01 |
| 4 | Examination of The Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit/hyperactivity disorder (ADHD) can present differently in individuals, with some individuals having difficulty with attentional control, hyperactivity, impulsivity, emotion dysregulation, and/or neurobehavioral functioning. The factors contributing to these different presentations remain unclear, but altered patterns of physical activity, sleep, and circadian rest/activity rhythms may play a key role. The goal of this study is to leverage wearable technology (i.e., a wristband) to investigate the relationships between physical activity during the day, sleep patterns and disturbances, and 24-hour circadian rest/activity rhythms with differences in ADHD symptoms, emotion dysregulation, … |
KERI ROSCH; | 2025-05-01 |
| 5 | Exploring Parameters of Driving Simulation in Relation to Drug Holidays in ADHD Patients PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit hyperactivity disorder (ADHD) or syndrome (ADHS) is a symptomatically defined condition that – if untreated – is linked to a significantly increased risk of traffic accidents. In a recent umbrella review, where data from reviews and meta-analyses on 21.142.129 adults was assessed, a pooled prevalence of 3.1% of ADHD in adults was estimated. Considering that globally around 1.35 million people lose their lives and more than 50 million are suffering from injuries or disabilities due to road accidents, … |
STEFAN LAKÄMPER; | 2025-05-01 |
| 6 | Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is an open-label trial of trigeminal nerve stimulation (TNS) for children aged 8-12 years with attention deficit hyperactivity disorder (ADHD) putatively due to prenatal alcohol exposure (PAE). TNS has been successful in treating pediatric ADHD generally and it is US Food and Drug Administration (FDA)-cleared for this condition. But this will be the first time it is tried for ADHD specifically associated with PAE. In TNS, … |
JOSEPH O’NEILL; | 2025-04-26 |
| 7 | The Effect of Dual-tasking Program on Cognitive and Physical Functions and Independence in Activities of Daily Living in Children with Duchenne Muscular Dystrophy: A Single-blind Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Duchenne Muscular Dystrophy (DMD) is an X-linked recessive disorder characterized by progressive muscle degeneration and frequent developmental, cognitive and behavioral impairments, occurring in one in 5000 live births of boys. DMD is caused by a deficiency of the protein dystrophin, which maintains the structure and functionality of muscle cells. The absence of dystrophin leads to the weakening and eventual death of muscle cells, resulting in reduced muscle strength and impaired motor function. In early childhood, children with DMD may experience delays in basic motor skills such as walking and standing. Later in life, … |
BAŞAK ÇAĞLA ARSLAN; | 2025-04-14 |
| 8 | A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-controlled, Trial to Evaluate The Efficacy and Safety of EB-1020 Once Daily QD XR Capsules Administered Orally at Low or High Dose in Adults With Attention-deficit/Hyperactivity Disorder PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the efficacy and examine the safety of two doses of EB-1020 QD XR capsule administered once daily orally in adult ADHD patients. |
OTSUKA PHARMACEUTICAL | 2025-04-01 |
| 9 | Prevalence of Neurodevelopmental Disorders in A Homeless Population – Pilot Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Introduction \& Central question: Psychiatric disorders are highly prevalent in the homeless population, however neurodevelopmental disorders are also at risk of leading to homelessness (Churchard et al., 2018; Casey et al., 2020). Research on this topic is poor in France. This research aims to study the prevalence in France of 3 neurodevelopmental disorders (NDDs) in a homeless population (Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder and Intellectual Developmental Disorder). Methods / approach: A 2 phase approach will be used including a screening phase and a diagnosis phase. This research is a pilot study that will include 150 homeless people, … |
CAROLINE DEMILY; | 2025-04-01 |
| 10 | Effect of Black Cumin Seed Oil on Cortisol, Stress and Quality of Life in Healthy Moderately-Stressed Adults PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary objective of this study will be to collect data to support the role of black cumin seed oil, also known as black seed oil (BSO), in moderating the stress response, including objective markers of stress (cortisol/DHEA) as well as subjective measures (mood/stress/sleep/beauty). The primary outcomes will be salivary cortisol, subjective stress, and psychological vigor. Subjects will be recruited from among the clients of the Certified Mental Wellness Coaches (CMWCs) that have passed the digital badge course via Marietta College (https://www.credly.com/org/marietta-college/badge/certified-mental-wellness-coach-cmwc-online). If volunteers meet the inclusion/exclusion criteria, they will review/sign the Informed Consent Form (ICF – … |
SHAWN TALBOTT; | 2025-04-01 |
| 11 | A Phase 2, Double Blind, Randomized, Placebo-controlled Crossover Trial to Evaluate The Efficacy and Safety of Atomoxetine in Adults with Melanocortin Obesity Syndrome PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a phase 2 randomized placebo-controlled crossover trial to determine the safety and efficacy of atomoxetine for treating obesity caused by loss-of-function variants in the melanocortin-4 receptor (MC4R), the most common cause of genetic obesity disorders. Atomoxetine was selected for this pilot trial because it has been shown to increase brain-derived neurotrophic factor (BDNF) within the central nervous system and in peripheral circulation. Targeting BDNF is a specific strategy for treating MC4R abnormalities because BDNF functions as a downstream mediator of MC4R signaling. |
JOAN HAN; | 2025-04-01 |
| 12 | (Neuro)Cognitive Remediation for Adults with Operational Stress Injuries PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: (Neuro)Cognitive remediation (CR) is an intervention for people experiencing cognitive impairments that interfere with their daily functioning. Cognition refers to a person’s ability to perceive, process, manipulate and respond to information. Attention, memory, abstract reasoning, and processing speed are all examples of cognitive skills. By focusing on improving these underlying skills, the overall aim of cognitive remediation is to improve the participant’s daily satisfaction and success. CR can be achieved through teaching compensatory strategies, … |
ABRAHAM RUDNICK; | 2025-04-01 |
| 13 | Investigation of Motor Development, Sleep Characteristics and Sensory Processing Skills of Infants with A History of Colic PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study was to evaluate the motor development, sleep characteristics and sensory processing skills of infants with a history of colic and to compare them with their peers without a history of colic. |
RABIA ZORLULAR; | 2025-03-12 |
| 14 | A Pharmaco-Imaging Trial of Mixed Amphetamine Salts for The Treatment of ADHD in Intellectually-intact Youth with Autism Spectrum Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: We are conducting a 10-week brain imaging and medication study. We are doing the research to study the response of ADHD in youth with ASD on extended-release formulation of mixed amphetamine salts (MAS) (also know as Adderall XR). We also want to find out if taking MAS has any effect on the brains of children and adolescents with ADHD and ASD. This study will help researchers better understand how the use of MAS to treat ADHD effects children and adolescents with ASD. We will compare MAS to a placebo. The placebo will look exactly like the MAS capsules but will contain no MAS. During this study, participants may get a placebo instead of MAS. Placebos are used in research studies to see if the study results are due to the study drug or due to other reasons. Participants with ASD and ADHD will complete 4-weeks of treatment with the study medication or placebo. They will complete bi-weekly study visits virtually via a telemedicine platform with the study doctor and complete questionnaires. On alternating weeks, they will meet with a MGH study team member to discuss medication adherence and potential side effects. Participants will have the option to attend all study visits in-person if you prefer. They will also complete baseline and endpoint MR scan visits at MIT. During the MR Scan visits, they will complete a series of tasks to measure inattention, impulsivity, reward sensitivity, decision-making, and working memory. Participants without ADHD or ASD will complete eligibility screening with MGH. If eligible, they will be invited to baseline and endpoint MRI scan visits at MIT. During the MRI Scan visits, they will complete a series of tasks to measure inattention, impulsivity, reward sensitivity, decision-making, and working memory. |
GAGAN JOSHI; | 2025-03-01 |
| 15 | Adults with Attention Deficit Hyperactivity Disorder / Substance Use Disorder Comorbidity in Integrated Treatment: Effectiveness and Feasibility PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) and Substance Use Disorders (SUDs) is a highly common comorbid condition associated with serious medical and psychosocial consequences. However, and despite the international consensus recommending integrated treatment for this comorbidity, few studies tested the efficacy of specific psychotherapeutic treatment for this comorbidity. The aim of this study is to test the efficacy of a specific group Cognitive and Behavioral Therapy (CBT) for the treatment of adults with this comorbidity. This is a longitudinal, randomized controlled intervention study utilizing a crossover design between the intervention and treatment-as-usual (TAU) waitlist condition, … |
NORMAN THERRIBOUT; | 2025-03-01 |
| 16 | Evaluating The Efficacy of Atomoxetine in Reducing Primary Nocturnal Enuresis in Children With ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: 1. Primary Aim: To evaluate the efficacy of atomoxetine in reducing the frequency of primary nocturnal enuresis episodes in children with ADHD. 2. Secondary Aim: To determine if improvements in attention symptoms correlate with reductions in nocturnal enuresis episodes. |
OSAMA IBRAHIM YOUNES; | 2025-02-28 |
| 17 | A Phase 2 Randomized Double-Blind, Parallel, Adaptive-Design, Clinical Trial to Evaluate The Safety and Efficacy of NRCT-101SR with NRCT-202XR Compared to NRCT-202XR Alone in Subjects with Attention-Deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: A combination therapy of NRCT-101 with NRCT-202 is being developed for patients with ADHD. |
NEUROCENTRIA | 2025-02-25 |
| 18 | Digital Health Intervention for Children With ADHD: Improving Mental Health Intervention, Patient Experiences, and Outcomes PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To conduct an RCT to evaluate the efficacy of the system, we will recruit 60 children (ages 8-12) with ADHD who will be randomized to either immediate (n=30) or delayed (n=30) treatment (i.e., a wait-list control group). Among those randomized to immediate treatment, half will be assigned to DHI (delivered via a smartwatch and smartphone application) and half will be assigned to an active control treatment as usual (TAU) group who will receive the smartwatch with no assigned activities, applications, or interventions on the devices. The intervention period will last 16 weeks; … |
SABRINA SCHUCK; | 2025-02-22 |
| 19 | Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Tourette syndrome (TS) is a complex neurodevelopmental disorder characterized by the occurrence of involuntary movements (motor tics) and vocalizations (phonic tics). The onset of TS is usually in childhood, and the prevalence of TS is estimated between 0.3 and 0.9% before the age of 18, decreasing progressively after that age. Most patients also suffer from associated psychiatric comorbidities (ADHD, OCD, mood disorders). Although the cause of TS remains unknown, the preferred hypothesis is the interaction of predisposing genetic factors and precipitating environmental factors (perinatal accidents, infectious diseases). From a pathophysiological point of view, it is widely demonstrated by structural, … |
EDOUARD COURTIN; | 2025-02-17 |
| 20 | Pai.ACT: An Artificial Intelligence-Driven Chatbot-Assisted ACT Mobile Platform With Mental Health Triage – A Randomized Controlled Trial and Regional Service Evaluation PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships. To address this gap, we have developed Pai.ACT, the first deep learning-based mental health advisory system for parents. Pai.ACT features an AI chatbot that integrates the counselling principles of Acceptance and Commitment Therapy (ACT) through natural language processing, providing parents with a human-like voice-to-text experience. Using data from chatbot interactions, … |
YUEN YU CHONG; | 2025-02-10 |
| 21 | Mental Health, Intellectual and Neurodevelopmental Disorder Detection with Artificial Intelligence Models: Testing Speech-Based Machine Learning Algorithms for Clinical Assessment and Risk Stratification in Mental Health Presentations PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, bipolar disorder, generalized anxiety disorder, major depressive disorder, obsessive compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and schizophrenia. We aim to develop tools that can support clinicians in making more accurate and efficient diagnoses. |
JULIANNA OLAH; | 2025-02-04 |
| 22 | A Pilot Study of A Remote Attention-Deficit/Hyperactivity Disorder Monitoring Program (RAMP) for Children in Rural Areas PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: RAMP is a pilot study examining the use of an Attention-Deficit/Hyperactivity Disorder (ADHD) Monitoring Program during the early stages of treating ADHD in children living in rural settings. This trial will enroll 36 caregiver/infant dyads across 2 sites and will evaluate feasibility endpoints rather than clinical outcomes. Enrolled participants will be randomized 1:1 to the intervention group (RAMP reports) or control group (digital education handouts). The study duration is 10 months, including start-up, enrollment and intervention, and data analysis and manuscript submission. |
HANNAH FORD; | 2025-02-04 |
| 23 | Intervention with Weighted Blankets for Children with ADHD and Sleep Problems: Implementation and Effectiveness PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim is to study a sleep intervention with weighted blankets in children with ADHD and sleep problems regarding 1) short- and long-term effects on sleep and health-related outcomes in comparison with standard treatment (melatonin), 2) barriers and facilitators to implementation in routine clinical practice, and 3) health-economic outcomes. |
INGRID LARSSON; | 2025-02-03 |
| 24 | Exploring Eye Vergence Markers in Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators study aims to evaluate the utility of eye vergence, an eye-tracking measure, as an indicator of visuo-spatial attention in children aged 4-17 years and adults, using computer-based eye-tracking tasks. Eye vergence, a binocular movement crucial for depth perception, has recently been linked to attentional control and neurodevelopmental conditions (NDCs) like ADHD and ASD. The investigators will work with children and adults from the CAN and Beckenham clinical centres to explore the relationship between eye vergence and diagnostic categories, potentially identifying subgroups with specific or overlapping attentional differences. This research may aid in the early detection of attention deficits, … |
ELIZABETH KILBEY; | 2025-02-01 |
| 25 | Assessment of Depression, Anxiety and ADHD Among Children and Adolescents with Congenital Heart Disease PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Congenital heart disease (CHD) is the most common birth defect, affecting ∼1% of all live births.The spectrum of CHD is wide, ranging from simple (not requiring immediate or possibly any surgical intervention) to severe or complex (typically defined as CHD requiring surgical intervention within the first month to year of life). |
SAMIA ASHRAF ABBDELGAWAD; | 2025-02-01 |
| 26 | Evaluation of The Effects of Different Dietary Practices on Quality of Life and Eating Behavior in Children with Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to investigate the effects of gluten-free casein-free diet and feingold diet on gastrointestinal system (GI) symptoms , eating behavior and quality of life in children with autism spectrum disorder. Research questions are below: Is there a difference in the effects of a gluten-free-casein-free diet and the Feingold Diet on GI symptoms? Is there a difference in the effects of a gluten-free-casein-free diet and the Feingold Diet on eating behavior? Is there a difference in the effects of a gluten-free-casein-free diet and the Feingold Diet on quality of life? |
SIMGE GÜREL; | 2025-02-01 |
| 27 | A Therapist-guided Online-delivered Group Counseling Program for Pregnant Women and New Mothers With ADHD: A Feasibility Study of AMOR; ADHD, Mothers Online Resources PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary aim of this study is to investigate the feasibility of the program AMOR for pregnant women and new mothers with Attention Deficit Hyperactivity Disorder (ADHD), by examining adherence, credibility, treatment satisfaction, and negative effects. The secondary objective is to obtain preliminary information about the short-term clinical outcomes of the program on self-report scales assessing symptoms of ADHD, stress, anxiety, depression, difficulties in emotion regulation, and quality of life. The main questions this study aims to answer: 1. To what extent will pregnant women and new mothers with ADHD adhere to, find useful, be satisfied with, … |
UNIVERSITY OF SOUTHERN DENMARK | 2025-01-22 |
| 28 | The Effects of Methylphenidate on Symptomatology in Individuals With Borderline Personality Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to investigate the effects of methylphenidate on symptomatology in individuals with borderline personality disorder. Specifically, it will evaluate whether Concerta is effective in reducing impulsivity, mood instability, and inattention among patients with BPD. Additionally, the study will assess Concerta’s safety profile in this population to determine its potential as a supportive pharmacological option in BPD management. |
OSAMA IBRAHIM YOUNES; | 2025-01-15 |
| 29 | VItamin D in PregnanCy for PrevenTion of EaRlY Childhood Asthma (VICTORY) PF:6 Related Papers Related Patents Related Grants Related Experts View Highlight: The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that supplementation in higher doses than recommended could reduce the risk of disease development. |
KLAUS BØNNELYKKE; | 2024-12-20 |
| 30 | CBG and Attention: A Double-Blind, Randomized, Placebo-Controlled Trial Examining The Effects of Cannabigerol on Indicators of Attention-Deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to evaluate the effects of Cannabigerol (CBG) on indicators of Attention-Deficit/Hyperactivity Disorder (ADHD) in a sample of participants indicating/reporting symptoms associated with ADHD. The main question it aims to answer is: Does CBG reduce ADHD-related indicators relative to placebo? Participants will administer an acute dose of placebo or 80mg CBG and complete outcome measures at 45 minutes and 75 minutes. Daily surveys to monitor safety will be administered for one week following administration. |
ELLEN LEEN-FELDNER; | 2024-12-14 |
| 31 | Effectiveness of A Positive Psychology and Mindfulness Based App for Parents of Children with A Neurodevelopmental Disorder (NDD): Study Protocol of A Pragmatic Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: An app based on positive psychology and mindfulness to support the mental well-being of parents of children with a Neurodevelopmental Disorder (NDD) was developed and will be evaluated on effectiveness. |
KIM TONIS; | 2024-12-03 |
| 32 | Effect of Vojta Therapy on Motor Control in Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD is generally associated with significant comorbidities including motor disorders in up to 96% of cases. Within these, disturbances of balance and motor coordination that interfere with school learning and daily activities are present in 47% of school children with ADHD. Therefore, the aim of this research is to determine whether Vojta therapy is beneficial for the improvement of balance, postural control, hand-eye coordination and manipulative motor skills in children with ADHD, hyperactive and/or combined, aged 6-12 years. |
JOSUE FERNANDEZ CARNERO; | 2024-11-30 |
| 33 | Non-randomized Controlled Pilot Study of A Health Promotion Program for Mothers of Children in The Ultra-orthodox Community: Examining Feasibility PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this study is to evaluate the feasibility and effectiveness of a health promotion intervention for Ultra-Orthodox Jewish mothers of children with ADHD. This study will examine the impact of a culturally tailored group-based intervention aimed at reducing stress, enhancing health, … |
ADINA MAEIR; | 2024-11-24 |
| 34 | Evaluation of Sustained Endogenous Attention Deficits in Attention Deficit Hyperactivity Disorder: Validation of A Computerized Neuropsychological Test. PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Subjects with ADHD may exhibit deficits in sustained internal attention. The Sustained-Paced Finger Tapping test was recently developed and experimentally used in international literature to assess sustained internal attention in typically developing children. This clinical study has several objectives: 1) to assess the presence of internal sustained attention deficits in children with ADHD through the Sustained-Paced Finger Tapping; 2) to evaluate the discriminant and ecological validity of the Sustained-Paced Finger Tapping. |
IRCCS EUGENIO MEDEA | 2024-11-11 |
| 35 | Clinical Study on Acupuncture Treatment for Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to evaluate the efficacy of acupuncture as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6-12 years. Using a mixed-methods approach, the research will triangulate data from acupoint data mining, treatment outcomes assessment, and patient perspectives to provide a comprehensive analysis of acupuncture’s potential therapeutic benefits for ADHD. This prospective cohort study will recruit children diagnosed with ADHD, … |
TANANAN SANGWANIT; | 2024-10-15 |
| 36 | Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to compare the effectiveness of a novel personalized surgical approach to the standard AT in children with small tonsils (ST). This will be accomplished by randomizing children with ST and OSA to one of these two treatments and comparing outcomes after 6 months. It is the investigators’ central hypothesis that a personalized drug-induced sleep endoscopy (DISE)-directed surgical approach that uses existing procedures to address the specific fixed and dynamic anatomic features causing obstruction (ie, … |
DEREK LAM; | 2024-10-04 |
| 37 | MultitArget STereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to investigate the neural mechanisms underlying Tourette syndrome (TS) and see if personalized deep brain stimulation (DBS) can help reduce tics in TS patients and improve related issues like anxiety, attention problems, and obsessive-compulsive behaviors. In this study, researchers will use stereoelectroencephalography (SEEG) and electrocorticography (ECoG) to record brain activity in key areas involved in movement and emotion, including the nucleus accumbens (NAc), anterior limb of the internal capsule (ALIC), insular cortex, anterior cingulate cortex (ACC), central medial thalamic nucleus (CM), globus pallidus internus (GPi), … |
JIANGUO ZHANG; | 2024-10-01 |
| 38 | Comparative Effects of Individual and Grouped Sensory Perceptual Motor Training on Gross Motor Skills and Quality of Life in Children With Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Autism is the most prevalent disorder as it affects attention, awareness, cognitive development, social development, and emotional aspects too. It is one of the comprehensive developmental disorders in the early stage, which is characterized by weak social learning and communication, limited activities, interests, learning, insufficient imaginative and stereotypical thinking or non-functional thinking of movements and verbalities. A lack of sensory perception leads to a leading autistic child's sensitivity to sensory stimuli or weak sensitivity and the child is not aware of the surrounding environment. |
SARA SATTAR; | 2024-09-26 |
| 39 | Development of A Novel Virtual Reality Treatment for Emerging Adults With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this pilot randomized clinical trial is to test the impact of a virtual reality program for improving the ability of emerging adults (age 18-25) with attention deficit hyperactivity disorder (ADHD) to stay focused while completing homework and studying. This study compares the impact of using a virtual reality headset to using a virtual reality headset while also receiving feedback about levels of focus to a control group. The main question is whether participants demonstrate significantly improved concentration while completing homework and studying in virtual reality and whether they enjoy and prefer working in a virtual reality environment. Concentration is measured both through participant report and also using keyboard and mouse click data to assess work productivity objectively. |
JOSHUA M. LANGBERG; | 2024-09-20 |
| 40 | Phase 3, Multicenter, 3-Week Fixed-dose, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy, Safety and PK Study of Evening Dosed Methylphenidate Hydrochloride ER Capsules (HLD200) in Children Aged 4-5 Years with ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the efficacy, safety and pharmacokinetics of HLD200 (20 mg and 40 mg) in children aged 4 to 5 years with ADHD. |
IRONSHORE PHARMACEUTICALS AND DEVELOPMENT | 2024-09-13 |
| 41 | A Randomized, Double-blind, Placebo-controlled, Parallel Arm Clinical Trial of De-Stress and Focus Capsule in The Management of Stress, Mental Alertness, Fatigue, and Anxiety PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The current study focuses in clinical validation of the efficacy of nutraceutical product in the management of mental focus and cognition. The benefits of these nutraceuticals extend beyond mere cognitive enhancement. Improved mental focus can lead to increased productivity and efficiency in both personal and professional settings. Individuals who struggle with attention deficits or cognitive fog may find that these supplements help them maintain a sharper and more consistent level of mental clarity. This can translate to better performance at work, as well as improved ability to manage daily tasks and responsibilities. |
RAMSHYAM AGARWAL; | 2024-09-05 |
| 42 | Extending The Reach of Evidence-based Practices to Support Student’s Attention and Behavior Through Technology PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to integrate digital health (dHealth) technology into the Collaborative Life Skills Program (CLS), an established, school-based behavioral intervention for students with ADHD, to make the program accessible to schools that serve students from low-socioeconomic (SES) backgrounds. Existing evidence-based interventions for students with ADHD are often inaccessible in schools with limited resources to support implementation. By adapting CLS to include a dHealth tool-CLS-D-investigators aim to improve the feasibility of intervention implementation in schools with limited resources and mitigate disparities in access to evidence-based interventions among students with ADHD who are from low-SES backgrounds. |
MIGUEL VILLODAS; | 2024-09-01 |
| 43 | Efficacy of Bifidobacterium Animalis Subsp. Lactis and Lacticaseibacillus Rhamnosus Mixture in Children With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study investigates WecProB (Bifidobacterium animalis subsp. lactis and Lacticaseibacillus rhamnosus) to evaluate their potential to improve symptoms and safety in children with ADHD. |
WECARE PROBIOTICS | 2024-09-01 |
| 44 | Efficacy of An Occupational Intervention for Quality of Work Life in ADHD: A Randomized Controlled Trial Protocol PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: An adaptation of the Minds@Work intervention to improve quality of life at work for adults living with attention deficit disorder with/without hyperactivity (ADHD), following a group format. |
GENEVIÈVE SAUVÉ; | 2024-08-28 |
| 45 | Klinefelter Syndrome – The Effect of Testosterone Treatment in Puberty. A Randomized, Double-blind Placebo-controlled Intervention Study: ‘The TiPY Study’ PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this randomized clinical trial is to study the effect of testosterone replacement therapy during puberty in boys with Klinefelter syndrome (KS, 47,XXY). The main questions to answer are how treatment with testosterone will affect body fat mass, lipid and glucose metabolism, growth and body proportions, bone mineralization as well as effects on neurocognitive development and emotional and social difficulties. Participants will be randomized to two years treatment with testosterone or placebo. |
LISE AKSGLÆDE; | 2024-08-15 |
| 46 | Effects of Low, Moderate, and High Intensity Exercise on Executive Function, Functional Impairment, and Symptom Severity in ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This project investigates the effects of a bicycling exercise at three levels of exercise intensity (low, moderate, and high) on attention deficit/hyperactivity disorder (ADHD) in college students. Specifically, the outcomes of interest in this study are self-reported executive functioning, self-reported functional impairment, and ADHD symptom severity. The hypothesis is that exercise will improve executive functioning, while reducing functional impairment and ADHD symptom severity, and that this response will be most pronounced in the high-intensity exercise group. |
KENT STATE UNIVERSITY | 2024-08-06 |
| 47 | Does The Format of The Adult ADHD Self-Report Scale Impact The Results: A Randomized Controlled Trial PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: The World Health Organization Adult ADHD Self-Report Scale v1.1 (ASRS) is frequently used in family medicine clinics to screen for ADHD. Numerous studies have found the ASRS has a low positive predictive value. Compounding this concern is the format of the ASRS. Specifically, the answers on the ASRS that lead to screen positive results are shaded in gray and grouped together, which may make it easy for patients to discern which responses should be selected for a positive screen. |
RONI KRAUT; | 2024-07-29 |
| 48 | The Effect of An Oligoantigenic Diet on Core Symptomatology of Children With Attention-Deficit /Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Fifty patients who diagnosed as ADHD syndrome according to Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM 5) Criteria aged from 6 to 16 years old will be assigned randomly into 2 arms: arm 1: the patients will follow food regimen that cover recommended daily allowance (RDA) for macronutrients and micronutrients suitable for their ages without any food restriction, arm 2: the patients will follow food regimen that cover (RDA) for macronutrients and micronutrients suitable for their ages based on Oligoantigenic diet (OAD). Psychiatric assessment will be done before intervention and after 3 months of intervention. |
HAYA ESSAM IBRAHIM; | 2024-07-01 |
| 49 | A Trial to Explore Performance and FMRI BOLD Signal Changes During Impulsivity Tasks in Impulsive Patients With Attention Deficit Hyperactivity Disorder and Borderline Personality Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a preceding study conducted to validate the methodology for assessing impulsivity by tasks and task-based fMRI measurements in patients with Attention Deficit Hyperactivity Disorder (ADHD) or Borderline Personality Disorder (BPD). |
SIMONE GRIMM; | 2024-07-01 |
| 50 | Examine The Effectiveness of Individualized Alpha Neurofeedback for Children with ADHD, A Triple-blinded Randomised Control Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders, characterised by inattention, hyperactivity, and impulsivity. Although pharmacotherapy is considered the first-line treatment for ADHD at all ages (at least for severe cases), non-pharmacological therapies might be equally effective without the risk of drug side effects. Some studies have shown that electroencephalographic (EEG) neurofeedback improves parent-rated ADHD symptoms in children and adolescents. However, whether neurofeedback is an effective treatment for ADHD is still under debate. Several issues may hinder the evaluation of the effectiveness of neurofeedback treatment in previous studies. Firstly, … |
WINNIE WAN YEE TSO (DR); | 2024-06-01 |
| 51 | The Effect of Vestibular and Proprioceptive Exercise Practices on Hyperactivity Levels in Children With Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to examine the effect of vestibular and proprioceptive exercise practices on the hyperactivity level in children with autism spectrum disorder. |
ÖĞR. ÜYESI ÖMER ŞEVGIN; | 2024-05-15 |
| 52 | Pharmacist Management of Attention Deficit Hyperactivity Disorder Medication Refill Requests: A Randomized Clinical Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This cluster randomized trial will compare pharmacist management of secure message requests for refills of attention deficit hyperactivity medications with primary care physician management regarding quality of care, timeliness of service, and parent care experience. |
TRACY A LIEU; | 2024-05-02 |
| 53 | Exposure Therapy for Anorexia Nervosa Pilot Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The current proposal will evaluate the feasibility, acceptability, and preliminary efficacy of Exposure Therapy for anorexia nervosa (AN) spectrum disorders (Exp-AN), an innovative treatment rooted in principles of inhibitory learning. Exp-AN will target anxiety about both eating and weight gain by combining in vivo (i.e., in real life) and imaginal (i.e., mental) exposure in novel ways (e.g., eating a feared food while listening to a recording describing fears about weight gain). |
JAMAL ESSAYLI; | 2024-05-02 |
| 54 | A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Study to Investigate The Efficacy, Safety and Tolerability of Oral Administered AK0901 Capsules in Children Aged 6-12 Years Old With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a Phase 3, multicenter, dose-optimized, double-blind, randomized, placebo-controlled study designed to evaluate the efficacy, safety, and tolerability of oral AK0901 capsules in children 6 to 12 years old with Attention Deficit Hyperactivity Disorder（ADHD）. |
SHANGHAI ARK BIOPHARMACEUTICAL | 2024-05-01 |
| 55 | Game-Based Digital Intervention for Depression in Adolescents PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to evaluate the effectiveness of digital interventions in treating depression and anxiety in adolescents. The main question it aims to answer is: Can digital interventions effectively alleviate symptoms of depression and anxiety in adolescents? The trial will include a comparison group where researchers will compare the effects of the digital intervention to traditional health education methods to assess their relative efficacy. Participants will be asked to engage with the digital intervention platform for a period of two months. |
ADAI TECHNOLOGY BEIJING | 2024-04-17 |
| 56 | Pharmacogenomics of Stimulant Treatment Response in Children and Adolescents with Attention-Deficit/ Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The Pharmacogenomics of Stimulant Treatment Response (PGx-STaR) study aims to identify genetic profiles related to methylphenidate treatment outcomes in children and adolescents aged 6-24 with Attention deficit/hyperactivity disorder (ADHD). |
CHAD BOUSMAN; | 2024-04-01 |
| 57 | The Effectiveness of MIND Diet and Forest Bathing on Reducing Psychological Stress Among Older Chinese: A Pilot Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This clinical trial aims to explore the effectiveness of the Mediterranean DASH Intervention for Neurodegenerative Delay (MIND) diet and Forest Bathing (FB) in reducing psychological stress among older Chinese individuals. The main questions it aims to answer are: 1. what is the effect of FB on stress reduction 2. what is the effect of MIND on stress reduction Participants of the MIND-FB group will participate will receive 1. FB: a two-hour FB session on four consecutive weekends in a country park, 2. MIND: four nutrition sessions, … |
FABIAN LING NGAI TUNG; | 2024-04-01 |
| 58 | Randomized Controlled Trial of A Behavioral Training App PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators propose addressing and evaluating the efficacy of a behavioral, contingency management app by conducting a randomized controlled trial (RCT) that will evaluate the app compared to a placebo app control group. Participants will be randomly assigned to immediate intervention using the treatment condition or to a placebo app condition. Participants will not know which condition they are assigned to until after the study completion; … |
ANIL CHACKO; | 2024-03-27 |
| 59 | Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions. This can affect their education, friendships, and daily life. Virtual reality-based games may help improve cognitive skills in children with ADHD. It may also help change how the brain functions. Objective: To see if virtual reality-based games help improve thinking skills and brain function in children with ADHD. Eligibility: Children aged 8 to 16 years with ADHD. Design: We will first do a pilot study, … |
SUSAN PERSKY; | 2024-03-15 |
| 60 | Assessment of Handwriting Skills in A Sample of Egyptian Children with Attention-Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: PURPOSE: To assess handwriting difficulties in ADHD children. BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders that affects 7.6% of children worldwide. In addition to the core symptoms defining Attention-Deficit/Hyperactivity Disorder (ADHD), ADHD children often experience motor problems, including graphomotor movements, leading to handwriting difficulties. Studies have confirmed that handwriting skills are adversely impacted by the presence of ADHD, and this is associated with lower academic achievement and self-esteem. Children with ADHD have been found to display greater difficulties in the development of motor coordination, especially in the planning and execution of complex, lengthy, … |
WALID SABER HUSSAIN; | 2024-03-15 |
| 61 | Researching The Effectiveness of Attexis, A Digital Health Application for Adults With Attention Deficit Hyperactivity Disorder – A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: In this randomized controlled clinical trial, 326 patients with ADHD will be investigated regarding the effectiveness of a digital therapeutic for improved ADHD symptomatology, the unguided online intervention attexis. Inclusion criteria are: male, female or non-binary, age 18-65, diagnosis of ADHD, elevated levels of ADHD symptoms (score of ≥17 either on the inattention subscale or on the impulsivity/hyperactivity subscale of the ASRS v1.1), stable treatment for at least 30 days at time of inclusion, sufficient German skills, … |
EVA FASSBINDER; | 2024-03-01 |
| 62 | Clinical Spectrum of Infants of Diabetic Mothers , in Neonatal Intensive Care Unit of Assiut University Children’s Hospital PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Determine spectrum of clinical presentations and complications associated with maternal diabetes mellitus in their newborns attending and admitted to Neonatal Intensive Care Unit of Assiut University Children’s Hospital. |
DINA NASSER MAHROUS DANIAL; | 2024-03-01 |
| 63 | Effectiveness of Technology-based Interventions for The Improvement of Cognitive Processes in Children and Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To scientifically demonstrate the improvements in cognitive functions and core symptoms of children and adolescents diagnosed with ADHD through the implementation of a cognitive rehabilitation program based on the use of the most relevant technologies found in the systematic review carried out during the first phase. Two intervention groups will be randomly assigned for the study: G1: composed of 20 patients who will receive neurocognitive therapy based on new technologies. This will be the experimental group. G2: composed of 20 patients who will receive conventional neurocognitive therapy for ADHD treatment. This group will be the control group |
ALEJANDRO CAÑA PINO; | 2024-03-01 |
| 64 | Cognitive Training Effects for Preschool Children With Attention Deficit Hyperactivity Disorder and Developmental Delays PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To explore whether children with Attention Deficit Hyperactivity Disorder and developmental delays who receive cognitive training and conventional rehabilitation can improve executive function more than traditional rehabilitation alone. A magnetoencephalographic examination will be arranged to explore how brain network activation works. Research method: 20 preschool children with Attention Deficit Hyperactivity Disorder and developmental delays under rehabilitation therapy will be collected. They will be randomly assigned to the experimental group (receiving rehabilitation therapy and three times per week for 15 minutes, … |
RU-LAN HSIEH; | 2024-03-01 |
| 65 | Impact of A Multidimensional Health Education Program on Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To measure the impact of a multidimensional health education program on patients’ adherence to the healthy life style and behavioral therapy , and to correlate it with severity of ADHD symptoms |
RASHA SAAD; | 2024-02-23 |
| 66 | Reprogramming Energy Homeostasis in Overweight Children and Adults Trough Exercise, Cognitive Training and Social Interaction PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The RESILIENT project is a clinical trial investigating leptin sensitivity in both children and adults with overweight or obesity. The study examines the additive effects of Cognitive Training (CT) and Social Training (ST) on leptin sensitivity, compared to stand-alone Intensive Health Behaviour Treatment (IHBT), which includes diet and Physical Activity (PA). The intervention will last for 8 weeks, followed by a 12-week washout period. A multilevel assessment will be conducted, … |
MELANIA MANCO; | 2024-02-08 |
| 67 | The Effects of An Online Mindfulness-based Intervention for Parents of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will investigate the effects of an online mindfulness-based intervention with a randomized controlled trial. |
LO HAY-MING HERMAN; | 2024-02-01 |
| 68 | A Phase 2/3 Randomized Double-Blind Placebo Controlled Clinical Trial to Evaluate The Safety and Efficacy of NRCT-101SR in Pediatric Subjects with Attention-Deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: To evaluate the efficacy and safety of NRCT-101SR compared to placebo in subjects 13-17 years of age with ADHD |
NEUROCENTRIA | 2024-01-25 |
| 69 | Training of Executive Functions Through The APP The Apollo & Rosetta Adventures PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD is one of the most prevalent neurodevelopmental disorders, with a strong impact on general functioning and in daily life. Executive Functions play an important role on this disorder, and numerous treatments have been developed over the years to try to contain its symptoms. The present study aimed to investigate whether the use of a video game, The incredible adventures of Apollo and Rosetta, could enhance Fxecutive Functions and improve the impact of symptoms in children with ADHD. A longitudinal study was carried out with 35 subjects aged 8 to 11 years. They were assessed twice, … |
GIAN MARCO MARZOCCHI; | 2024-01-09 |
| 70 | A Randomized, Controlled, Parallel-Group, Intervention Study to Assess At-Home, Digital Therapy for Treating Adult Participants Ages 18-50 Years Old With Attention Deficit Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this clinical trial is to evaluate the effects of mobile app digital therapies on cognitive function and symptoms in adults diagnosed with ADHD. |
ROBERT BILDER; | 2024-01-03 |
| 71 | Therapeutic Effects of Multiple-strain Probiotics for Children With ADHD Based on Assessment of Standardized Attention Tests and Quantitative Electroencephalogram: A Single Arm Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Probiotics are widely used as supplement for various neurodevelopmental disorders. The mechanism of their therapeutic potential lies in the gut-brain axis, a two-way communication pathway through the neuroendocrine system. In the past, there have been many experiments to study the possible efficacy of probiotics in patients with ADHD. Although some studies have shown that probiotics can improve ADHD symptoms, most studies have used behavioral rating scales to evaluate. As a result, … |
CHENG YU-SHIAN; | 2024-01-03 |
| 72 | Cognitive Rehabilitation Training for People With Multiple Sclerosis: A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Cognitive rehabilitation is designed to enhance a person’s capacity to process and interpret information and improve their ability to function in all aspects daily, family and community life. Given the clear and consistent documentation of cognitive deficits in persons with MS, the most notable deficit being information processing speed, learning and memory and executive function, there is an obvious need for effective cognitive rehabilitation. The proposed study will be a randomized controlled single-blinded trial with treatment and wait-list control group. The treatment group will be administered the Goal Management Training (GMT) program; … |
ANTHONY FEINSTEIN; | 2024-01-02 |
| 73 | A Phase IV, Open-Label, Decentralized Clinical Trial to Evaluate The Efficacy and Safety of Qelbree® in Adults With Attention-Deficit/Hyperactivity Disorder and Mood Symptoms PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: Open label, flexible dose, decentralized clinical trial evaluating the efficacy and safety of SPN-812 in adults with ADHD and mood symptoms. |
SUPERNUS PHARMACEUTICALS | 2024-01-01 |
| 74 | Testing The Potential of High-dose Vitamin B6 Supplements for Sensory Reactivity in Autism PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This clinical trial aims to explore the effect of Vitamin B6 supplementation on anxiety sensory hyperreactivity in autistic adults. Researchers will compare a placebo group to high-dose Vitamin-B6 to see if vitamin B6 reduce anxiety and sensory reactivity differences in autism. |
DAVID FIELD; | 2024-01-01 |
| 75 | Psychiatric Comorbidities in Children With Generalized Epilepsy PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Epilepsy is defined as a chronic disorder that presents with recurrent episodes of unprovoked seizures. Epileptic seizures are caused by excessive excitation of cortical neurons. The condition has various etiologies and comorbidities. Classification; The Classification of Epilepsies includes several diagnostic levels (steps): 1. from seizure type to epilepsy type (generalized/focal/combined generalized and focal/unknown) 2. etiology (genetic/ structural/ infectious/ metabolic/ immune/unknown). A clinician can use any level of the classification |
ASMAA GAMAL HASHEM; | 2023-12-30 |
| 76 | Immunoprofilling of Peripheral Blood Mononuclear Cells in Children With Attention Deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this observational study is to learn about The immune cell landscape of peripheral blood mononuclear cells in children with ADHD compared to typically developing controls. The main question it aims to answer are: 1.Testing the differences in immune cell subpopulations, protein expression and signaling pathways and cell subsets between two groups 2. Exploring the correlations between immune function in PBMC and resting-state brain functional networks in children with ADHD. Participants will be taken peripheral blood about 5 ml , cognitive assessment including Intelligence testing, Stroop color-word test and Trail making test, … |
HU GUANGHUI; | 2023-12-04 |
| 77 | Behavioral and Neural Target Engagement for ADHD Executive Working Memory Training PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The proposed study will replicate target engagement as assessed in the first phase while also determining if it correlates with clinically meaningful improvements in ADHD dysfunction |
MICHAEL C STEVENS; | 2023-12-01 |
| 78 | Effects of An Aerobic Exercise Intervention on Core Symptoms, Executive Functioning, and Quality of Life in Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Selecting a maternal and child healthcare hospital in Shenzhen City, Guangdong Province, 50 cases of ADHD children as the study subjects, according to the inclusion and exclusion criteria to screen the eligible study subjects, introduction of the purpose and process of the study, informed consent to enrolment, the children were divided into the intervention group and the control group. The experimental group used aerobic exercise, while the control group was given daily physical activity, and general information questionnaires, Conners Parental Symptom Questionnaire, SNAP-IV scale, Stroop Colour Word Test, Rey Complex Graphics Test, Connection Test, Children’s Depressive Disorder Self-assessment Scale, … |
LINGRONG XIAO; | 2023-11-28 |
| 79 | Retrospective Study of The Acceptability and Effectiveness of A Dialectical Behavioral Therapy Group in Patients Suffering From Emotional Dysregulation (Borderline Personality Disorder, Bipolar Disorder and Adult ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Emotional dysregulation (ED) is a common syndrome in psychiatric disorders. It is characterized by intense emotions, easily triggered, and with significant psychological impact: explosions of anger, irritability, impulsivity, emotional lability, etc. It is systematic in borderline personality disorder, and observed in a majority of patients with bipolar disorder. (even in the interictal period), adult ADHD, or addictions. ED is a cause of psychological distress, suicidal behavior or non-suicidal self-injury, … |
SÉBASTIEN WEIBEL; | 2023-11-21 |
| 80 | An Open-Label Treatment, Investigator-Initiated Study, on The Duration and Efficacy of Azstarys (Serdexmethylphenidate and Dexmethylphenidate) on Adult ADHD Symptoms and Executive Function in Early Evening PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a single-site study. One purpose of this trial is to extend the safety and efficacy evidence basis for Azstarys in adults with ADHD. This open-label, treatment study will examine the efficacy of Azstarys on ADHD symptoms using the AISRS 18-item total score on the AISRS-expanded; the Adult ADHD Investigator Symptom Rating Scale. The investigators will also examine Executive Function later in the day (early evening, about 12 hours after first morning dosing). |
LENARD ADLER; | 2023-11-13 |
| 81 | Open-Label Trial of Personalized Medication Experiments to Inform Decisions About Future Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Use PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary goal of the project is to test personalized medication experiments to inform decisions about future medication use. Our central hypothesis is that our intervention will lead to within subject increases in adolescent involvement in decision making and decreases in uncertainty about future medication use. The investigators view this open label trial as a pilot study to test the feasibility, acceptability, and preliminary efficacy of the medication experiment intervention and therefore warrants further testing in a future larger trial. |
WILLIAM BRINKMAN; | 2023-11-10 |
| 82 | Efficacy of Visual Focusing Game on Children With Attention Deficit Hyperactivity Disorder and Mechanisms of Functional Near-Infrared Spectroscopic Imaging PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a single-center, randomized, double-blind, sham-controlled study that will recruit children with attention deficit hyperactivity disorder and randomly assign them to a test group and a control group. The patients in the test group will be given a visual focus game to play and the patients in the control group will be given an animated video of the game that had no therapeutic effect. Treatment will be required at least 5 times per week for 2 weeks, … |
MIN CAI; | 2023-11-10 |
| 83 | Understanding The Neural Mechanism Behind Sensory Processing Anomalies PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To assess sensory processing anomalies in neurotypical children, children with autism spectrum disorder, and attention-deficit hyperactivity disorder, particularly within the vibrotactile and auditory sensory modalities. |
DANIEL SKAK MAZHARI-JENSEN; | 2023-11-01 |
| 84 | Flashed Light Therapy for Adolescents with ADHD and Delayed Sleep Timing Related Papers Related Patents Related Grants Related Experts View Highlight: The primary aim of the present research project is to examine the feasibility, as measured by treatment perceptions, and tolerability, as measured by adherence and attrition, of two weeks of flashed light therapy alone followed by four weeks of daily flashed light therapy combined with four weekly videoconference-delivered cognitive behavioral therapy sessions targeting circadian rhythms and sleep in four adolescents aged 14 to 17 years with attention-deficit/hyperactivity disorder and delayed sleep-wake schedules. |
EMILY J. RICKETTS; | 2023-10-20 |
| 85 | Comparing The Effects Of Cognitive Behavioral Therapy And Motor Learning Technique in Adults With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of our study to compare the effect of cognitive behavioral therapy and motor learning techniques in adults with Attention Deficit Hyperactivity Disorder. and help the adults to address and revise cognitive distortions and habits affecting your productivity and emotional mindset.participant allocated to control group will be asked to perform cognitive behavioural therapy and participants allocated to experimental group will be asked to perform motor learning activities and cognitive behavioral therapy. |
SHALAMAR INSTITUTE OF HEALTH SCIENCES | 2023-10-02 |
| 86 | Evaluation of Micronutrient Levels and Micronutrient Supplement Use in Patients Hospitalized in The Pediatric Palliative Care Service PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this observational study is to determine the micronutrient levels and frequency of use of micronutrient supplements in patients in the Pediatric Palliative Care Clinic. The main questions it aims to answer are: – What is the frequency of micronutrient deficiencies in pediatric palliative care patients? – What is the frequency of micronutrient supplement use in pediatric palliative care patients? |
DERŞAN ONUR; | 2023-10-01 |
| 87 | Assessment of ARVO Web-based Software for Evaluating Attention-Deficit/Hyperactive Disorder (ADHD) Symptoms in Children. Prospective, Controlled Clinical Investigation PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Clinical investigation is aimed to assess the performance and safety of web-based ARVO 2.0, for evaluating possible Attention-Deficit/Hyperactive Disorder (ADHD) symptoms in children. Possible ADHD symptoms are recorded by using specific predetermined neurocognitive performance indicators (NPI’s), derived during/from the game. Results of ARVO are compared to the Conners Continuous Performance Test 3rd Edition™ (CPT 3) that is a task-oriented, automated 14-minute computerized assessment of attention-deficit (AD) related problems in individuals aged 8 years and older. Performance and safety of ARVO and CPT 3 are compared in two clinical investigation populations, … |
SAMI LEPPÄMÄKI; | 2023-10-01 |
| 88 | Methylphenidate and Response to Alcohol Cues (MARA) Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate affects responses to alcohol cues. The study will observe the effects of methylphenidate or a placebo on attentional bias and craving responses to alcohol cues through fMRI, EEG, and behavioral testing. Participants will be involved in one remote and two in-person sessions. |
UNIVERSITY OF FLORIDA | 2023-10-01 |
| 89 | Investigation of Locus Coeruleus Function in Sustained Attention PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The norepinephrine-producing locus coeruleus (LC) is thought to be central to a wide array of cognitive functions, like attention and goal pursuit, and has been implicated in dysfunctions including attention deficit hyperactivity disorder and schizophrenia. The goal of this proposal is to develop methods that permit measurement of activity in the human LC. Because the LC is small and located in the pons, the Investigators will use high resolution magnetic resonance imaging techniques tailored to the brainstem environment, including neuromelanin-sensitive images shown to delineate the LC, combined with pharmacological manipulation to confirm the location of functional activity. |
JULIE SCHWEITZER; | 2023-10-01 |
| 90 | Personalizing Behavioral Parent Training: Improving Reach and Outcomes for Families of Children With Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of the study is to develop and refine a personalized behavioral parent training intervention for caregivers of children with attention deficit hyperactivity disorder (ADHD). The behavioral intervention will teach positive parenting through videos and quizzes that caregivers can access through a smartphone application. The program also gives parents and caregivers in-the-moment feedback their use of parenting strategies. The current study, a micro-randomized trial, aims to see whether the in-the-moment feedback given to parents (a push notification on their smartphone) changes parenting behavior right after the feedback. Micro-randomized means that parents are randomly assigned repeatedly, … |
FLORIDA INTERNATIONAL UNIVERSITY | 2023-10-01 |
| 91 | Effect Mindfulness Based Training on Attention, Hyperactivity and Emotion Regulation Among Children With ADHD: A Randomized Controlled Trails PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Mindfulness training is a promising form of training for children with ADHD, as it focuses on attention and has gained empirical support as a complementary or alternative intervention. It involves increasing awareness and nonjudgmental observation of present-moment experiences while reducing automatic responding |
ALEXANDRIA UNIVERSITY | 2023-10-01 |
| 92 | Preliminary Evaluation of The Reliability and Validity of The Attention Rating Scale in Patients With Depression and Insomnia Disorders PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study, based on preliminary experimental results, literature review, and expert consultations, developed the Attentional Rating Scale (ARS). The aim was to rapidly assess participants’ attention and potential influencing factors. The research focused on the scale’s reliability and validity among healthy adults. Additionally, the Attention Network Test (ANT) served as the gold standard for evaluating attention. The study attempted to identify correlations between various dimensions of attention and the three attentional networks. |
XUEQIN WANG; | 2023-09-28 |
| 93 | The Effect of Cognitive Behavior Therapy-Based Psychoeducation Given to Children With Attention Deficit Hyperactivity Disorder on Children’s Quality of Life, Anxiety and Depression PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study was planned to determine the changes that cognitive behavior therapy-based psycho-education against the negativities brought by the disease in the long term of children diagnosed with Attention Deficit Hyperactivity Disorder will create changes in the child’s quality of life, anxiety and depression status and disease symptoms. As a result of this study, if cognitive behavior-based psycho-education has a positive effect on anxiety, depression and quality of life of children with Attention Deficit Hyperactivity Disorder, … |
VEDAT ARGIN; | 2023-09-25 |
| 94 | Internet-Assisted Behavioral Parent Training Intervention for Children With Attention Deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to investigate the effectiveness of an Internet-Assisted behavioral parent training intervention on children’s ADHD symptoms and children’s and parents’ mental health status. |
WUHAN MENTAL HEALTH CENTRE | 2023-09-12 |
| 95 | The Acceptability and Effectiveness of Formal Versus Informal Mindfulness Instruction Among University Students With Self-reported ADHD, Lived Experience of Nonsuicidal Self-injury, or Stress: An Online Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The present study will use a randomized controlled design to investigate group differences between university students with self-reported stress (comparison group), ADHD, or a history of nonsuicidal self-injury (NSSI) in response to a four-week mindfulness instruction program across conditions (formal mindfulness program, informal mindfulness program, inactive control) in terms of the intervention’s acceptability and effectiveness. |
NANCY L. HEATH; | 2023-09-06 |
| 96 | Effect of A Self-hypnosis Smartphone Application on Attention Disorders and Anxiety in Children With Attention Deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The prevalence of Attention Deficit/ Hyperactivity (ADHD) varies between 3 and 10% depending on the studies. Comorbidities are frequently associated, in particular anxiety disorders. School, social and family consequences of ADHD can be major, especially in the presence of a comorbidity. The study goal is to evaluate, through questionnaires, the effect of self-hypnosis via a smartphone application, … |
CATHERINE GROSMAITRE; | 2023-09-04 |
| 97 | Vitamen D in Autism PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: In the present study, we aim to evaluate the serum level of 25 hydrxy vitamin D in autistic children . |
AHMED ABDELMONEIM AHMED; | 2023-09-01 |
| 98 | An Investigation of Vocal Hygiene, Vocal Behaviors, and Quality of Life Associated With Voice in Children With and Without Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim is to gain information about vocal hygiene knowledge level, phonotrauma behavior frequency, voice-related quality of life, and voice handicap index scores in children diagnosed with ADHD aged 8 to 11, through inter-group comparisons of scale and questionnaire data between children diagnosed with ADHD and control group participants aged 8 to 11. |
ÖZLEM BEŞIK TOPÇU; | 2023-08-31 |
| 99 | Taurine Supplementation Improves Core Symptoms in Children With Autism Spectrum Disorders: An Exploratory Randomized, Double-blinded, Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: In the treatment of autism spectrum disorders (ASD), medication is only an adjunct, and the main treatment modalities are education and behavioral therapy. People with autism incur huge medical and educational costs, which puts a great financial burden on families.Taurine is one of the abundant amino acids in tissues and organs, and plays a variety of physiological and pharmacological functions in nervous, cardiovascular, renal, endocrine and immune systems. A large number of studies have shown that taurine can improve cognitive function impairment under various physiological or pathological conditions through a variety of mechanisms, … |
HAO ZHOU; | 2023-08-18 |
| 100 | Early Life Anemia and Children’s Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies PF:10 Related Papers Related Patents Related Grants Related Experts View Highlight: The overall project aim is to study children’s neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year of life using national and regional Swedish health-data registers, and to assess children’s neurodevelopmental outcomes over the range of maternal hemoglobin levels during pregnancy. |
RENEE GARDNER; | 2023-08-15 |
| 101 | Acceptability, Feasibility, and Development of An AI Driven, Multi-sensor, Non-invasive Digital Mental Health Platform in Children With ADHD and Emotional Symptoms PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is an observational study collecting data using a wearable to measure the biometric features in youth with Attention deficit hyperactivity disorder(ADHD) and Autism. |
MAXISHEALTH | 2023-08-09 |
| 102 | El Faro: Addressing Mental Health Inequities Among Latinx Children With ADHD in Durham PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Study team members from El Futuro in Durham, North Carolina have created an intervention called El Faro. El Faro helps Latinx families of children with ADHD understand and cope with the stress and difficulties presented by the disorder. We propose to develop a community-engaged research partnership between El Futuro and the Duke ADHD Program that aims to pilot-test an adapted El Faro treatment. |
JOHN MITCHELL; | 2023-08-01 |
| 103 | A Randomized Effectiveness Trial of Metacognitive Self Control and Job Interview Training PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study is a randomized controlled trial (RCT) that assesses the effectiveness of a metacognitive self-control training intervention (MCT) in conjunction with virtual-reality job interview training (VR-JIT) in a sample of formerly incarcerated individuals. The study also includes an implementation evaluation. |
MATTHEW SMITH; | 2023-08-01 |
| 104 | Mindfulness and Cognitive Training Programs for Children With Attention Deficit Hyperactivity Disorder (ADHD): A Randomized, Controlled Trial (the NeuroMind Study) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The present project will evaluate through a Randomized Controlled Trial (RCT) with 5-month follow-up, the efficacy (5-month time horizon), adjunctive to TAU, of three 8-week interventions: a) the Mindfulness for Health program (i. e., M4H), b) a Cognitive Training (CT) program through NeuronUp platform and a program combining both (Mindfulness and Cognitive Training program, i. e., UP4H), a, as compared to TAU, in children (7-12 years old) with ADHD. In order to evaluate stability of clinical changes and to determine the mechanisms of action of the interventions studied, … |
ANNA HUGUET; | 2023-07-20 |
| 105 | EFFECTIVENESS OF VIRTUAL REALITY GLASSES VERSUS WHITE NOISE ON DENTAL ANXIETY IN CHILDREN WITH ATTENTION DEFICIT/ HYPERACTIVITY DISORDER(A RANDOMIZED CONTROLLED CLINICAL TRIAL) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The present study aims to assess and compare the effectiveness of distraction technique using virtual reality glasses and white noise with basic behavior guidance techniques on dental anxiety in children with Attention Deficit/ Hyperactivity Disorder. |
NAHLA ALY; | 2023-07-10 |
| 106 | A Phase 3, Randomized, Double-blind, Placebo-controlled Trial of Solriamfetol in Adults With ADHD PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: FOCUS (Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol) is a Phase 3, multi-center, randomized, double-blind, placebo-controlled, parallel- group trial to assess the efficacy and safety of solriamfetol in adults with ADHD. |
AXSOME THERAPEUTICS | 2023-07-06 |
| 107 | Assessing The Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Undiagnosed Young Adults:A Cross Sectional Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: To asses the prevalence of Attention deficit hyperactivity disrorder in undiagnosed young adults. |
AINA MARZIA SYED; | 2023-07-01 |
| 108 | A Phase 3, Dose-Optimized, Double-Blind, Randomized, Placebo-Controlled, Parallel Efficacy and Safety Laboratory Classroom Study in Children (6-12) With Attention-Deficit/Hyperactivity Disorder (ADHD) Using CTx-1301 (Dexmethylphenidate) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to evaluate the efficacy and safety of CTx-1301 in children (6-12) with ADHD in a laboratory classroom setting. |
CINGULATE THERAPEUTICS | 2023-07-01 |
| 109 | Investigating The Fine and Gross Motor Performance in Children With Attention Deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Children with ADHD have difficulties with co-contraction, producing muscle force, and regulating movement velocity, and physical fitness. The purpose of this study was to compare the gross and fine motor abilities in children with ADHD and children with typical development. |
OZGUN KAYA KARA; | 2023-06-30 |
| 110 | Transcranial Photobiomodulation for Adult ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to assess the behavioral as well cognitive changes in ADHD symptoms in terms of improvement of inhibitory control and attention in adults with ADHD |
CNS ONLUS | 2023-06-15 |
| 111 | A Phase 3, Double-blind, Randomized, Placebo-controlled, Multi-center, Fixed-dose, Parallel Group Efficacy and Safety in Pediatrics (6-17) With Attention-Deficit/Hyperactivity Disorder (ADHD) Using CTx-1301 (Dexmethylphenidate) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: A Phase 3, randomized, double-blind, placebo-controlled, multi-center, fixed-dose, parallel-group efficacy and safety study in a pediatric population (6-17) with Attention-Deficit/Hyperactivity Disorder (ADHD) using CTx-1301 (d-MPH). A multi-center, double-blind, randomized, placebo-controlled, fixed-dose, parallel efficacy and safety study with CTx-1301 in children (6-12) and adolescents (13-17) with ADHD confirmed by an ADHD-RS-5 score of at least 28 and CGI-S score of at least 4 (moderately ill) at screening. The study will be comprised of a screening period, a double-blind randomized phase, and a safety follow-up visit. |
ANN CHILDRESS; | 2023-06-01 |
| 112 | Observational, Multicentre, Prospective Study to Assess ADHD In Adult Patients With Inadequate Response to Treatments For Other Resistant Psychiatric Pathologies In Five Countries PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The main aim of this study is to find out how many adults with certain psychiatric conditions who didn’t respond to their current treatment are underdiagnosed as having ADHD. No study medicines will be provided to participants in this study. The study sponsor will not be involved in how participants are treated but will provide instructions on how the clinics will record what happens during the study. At their first clinic visit, … |
TAKEDA | 2023-06-01 |
| 113 | Motor Skills in Children With Attention Deficit and Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Physiotherapists have positive effects on motor skills, executive functions and symptoms of children with attention deficit and hyperactivity disorder. However, progression takes time due to the symptoms of the disease. Physiotherapists need strategies to manage the symptoms of ADHD. Music can be used as a strategy because music is known to reduce the symptoms of children in this group. There is no study in the literature on how motor skills will be affected with musical accompaniment. The aim of this study is to compare motor skills performed with and without music in children with ADHD. When we evaluate motor skills like in a treatment session, the usability of music as an environmental factor will be investigated according to the positive, negative or ineffective results of the music effect. |
ZEHRA GÜÇHAN; | 2023-06-01 |
| 114 | Use of Animation in Therapy: Effects on Symptom Levels of Children With Attention Deficit and Hyperactivity Disorder, A Randomized Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of the study is to determine the effects of animation therapy on the main symptoms of Attention Deficit – Hyperactivity Disorder; hyperactivity, inattention and impulsivity. |
OZGUN BELEN; | 2023-05-15 |
| 115 | The Secret Trail of Moon (MOON): A Personalized Treatment Video Game for Children and Adolescents With ADHD Based on Cognitive Training and Self-regulation PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is the most common neurodevelopmental disorder in childhood and adolescence (5%) with associated difficulties and worse prognosis if undetected. Multimodal treatment is the treatment of choice, however, sometimes it can be insufficient or have some drawbacks. Objective: To demonstrate the effectiveness of cognitive training through the video game ‘The Secret Trail of Moon’ (MOON) in improving emotional regulation of ADHD in people aged 7 to 18 years. Hypotheses: H1: ADHD patients using MOON improve their emotional regulation more than the control group; … |
HILARIO MANUEL BLASCO FONTECILLA; | 2023-05-09 |
| 116 | A Multicenter, Dose-Optimized, Open-Label, Safety/Tolerability and Pharmacokinetic Study With Azstarys® in Children 4 and 5 Years of Age With Attention-Deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The is a multicenter, dose-optimized, open-label, safety/ tolerability and pharmacokinetic (PK) study with Azstarys® in children 4 and 5 years of age with attention-deficit/hyperactivity disorder (ADHD). The primary objective is to determine the safety and tolerability of treating children 4 and 5 years-of-age with ADHD with Azstarys® for up 12 months. Approximately 100 subjects will be enrolled. Approximately 20 sites will participate. |
ANN CHILDRESS; | 2023-05-01 |
| 117 | Double-blind, Randomized, Parallel Group, Placebo Controlled Clinical Trial to Evaluate The Effects of Atomoxetine on Impulsivity in Behavioral Laboratory Tasks in Adult ADHD Patients PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary objectives are to investigate the effect of atomoxetine on impulsivity after single dose and at steady state measured by the total score of Barrett Impulsiveness Scale version 11 (BIS-11) and Short Urgency, Perseverance, Premeditation, and Sensation Seeking-Positive Urgency Impulsive Behavior Scale (S-UPPS-P) Impulsive Behavior Scale. The secondary objective is to evaluate the safety of atomoxetine. |
BOEHRINGER INGELHEIM | 2023-04-17 |
| 118 | An Adjunct Study to Assess Guided ADHD Therapy for Managing The Extent and Severity of Symptoms – A Prospective, Multicenter, Open Label, Single Arm, Intervention Study to Assess Efficacy and Safety of An At-home, Game-based Digital Therapy for Treating Clinical Symptoms of Adult Patients With Attention-Deficit/Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The objective of this study is to assess the safety and effectiveness of an at-home, game-based digital therapy for treating adult patients with Attention-Deficit/Hyperactivity Disorder (ADHD). |
GREG MATTINGLY; | 2023-04-15 |
| 119 | Focus Groups to Optimize Research Methodology in A Multinutrient Study of Racially and Ethnically Diverse Children With ADHD and Emotional Dysregulation PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Focus groups to identify treatment needs and barriers to participation in the planned multinutrient study among racially and ethnically diverse (Black and Hispanic) communities. |
JEANETTE JOHNSTONE; | 2023-04-15 |
| 120 | The Difference in Pharmacodynamic and Pharmacokinetic Profiles Between Tentin and Magisterial Dexamfetamine in Adults With Attention Deficit Hyperactivity Disorder, A Double Blinded Randomised Crossover-controlled Trial Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to compare in the pk/pd profiles of magisterial dexamfetamine and Tentin in adults with Attention Deficit Hyperactivity Disorder (ADHD). The main question\[s\] it aims to answer are: Q1: is there a difference between pk/pd profiles of the two forms of dexamfetamine? Q2: how does the pharmacokinetic variability influences the objective and subjective (side) effects experienced by adult patients with ADHD? Participants will: * take the Quantified behavior Test for analysis of objective effects. * undergo blood sampling for analysis of the plasma concentration of dexamphetamine. * undergo blood pressure and heart rate measurements. * fill out 4 types of questionnaires. Researchers will compare the outcomes between magisterial dexamphetamine and Tentin use in a crossover setting. |
GLENN DUMONT; | 2023-04-14 |
| 121 | A Retrospective, Non-interventional, Single-center Study to Describe A Spanish Cohort of Patients With FMF and to Identify Suboptimally Treated Patients With Minimal Disease Activity and Its Impact on HRQoL (Health-Related Quality of Life) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: A retrospective, non-interventional, single-center study conducted in Spain, based on the collection of data from the medical histories of patients with Familial Mediterranean fever (FMF) diagnosed during childhood from January 2005 to December 2021. Data from the patients’ medical records was collected retrospectively, from the time of diagnosis to the current moment of the patient’s enrollment in the study. Patients had a minimum follow-up of 3 months after diagnosis. |
NOVARTIS PHARMACEUTICALS | 2023-03-30 |
| 122 | How Related Are Speech Production and Reading? An Investigation of The Impact of Motor Tasks and Lidocaine on Reading Unfamiliar Words in Adults With and Without Dyslexia PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Recent claims report that reading ability is partially dependent on speech production. While the evidence for this claim is compelling, it is not known to what extent, the speech production system contributes to successful reading performance in adult populations with dyslexia. One direct way to determine the influence of speech production feedback on reading performance is to measure reading performance in adults with dyslexia with an added motor component (i.e., sucking on a lollipop, holding a bite bar or numbing their oral mucosa with lidocaine). To adults with and without dyslexia 18 years of age and older (60 in total; … |
UNIVERSITY OF ALBERTA | 2023-03-27 |
| 123 | Impact of Neuro-linguistic Programs on The Academic Performance of Primary School Students in Lebanon: Triggers, Attention Deficit Hyperactivity Disorder Symptoms and Their Effect on Behavior and Academic Performance of Schoolchildren PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Neuro-Linguistic Programming (NLP) is a methodology developed in the 1970s by Richard Bandler and John Grinder, based on the idea that language and behavior are interconnected and can be systematically modeled and changed. NLP is often used as a form of psychotherapy, coaching, or personal development, although its effectiveness has been debated in the scientific community. NLP practitioners believe that our thoughts, emotions, and behavior are influenced by our internal representations of the world, which are constructed through language and sensory experiences. Changing the use of language and the perception of experiences, thoughts, emotions, … |
GEORGES HATEM; | 2023-03-20 |
| 124 | Mind The Heart – Mental Health in Children and Adolescents With Congenital Heart Defects in Denmark PF:6 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of the Mind the Heart study is to document the feasibility of an online parent/child administered screening model for mental disorders (MDs) in Danish children and adolescents with congenital heart disease (CHD). As MDs in children and adolescents with chronic somatic health issues are frequently underdiagnosed and undertreated, we further aim to develop a website with evidence based information on mental health in children and adolescents with CHD in order to promote knowledge and awareness among families and health professionals across sectors. |
SARA HIRANI LAU-JENSEN; | 2023-03-17 |
| 125 | A Multicenter, Dose-Optimized, Randomized, Double Blind, Efficacy and Safety Study With Azstarys® in Children 4 to 12 Years of Age With Attention Deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a multicenter, dose-optimized, randomized, double-blind, efficacy and safety study with Azstarys® in children 4 to 12 years of age with attention-deficit/hyperactivity disorder (ADHD). Azstarys® contains dexmethylphenidate (d-MPH) and serdexmethylphenidate (SDX), … |
ANN CHILDRESS; | 2023-03-01 |
| 126 | Research on The Development of Attention and Its Relationship With Emotions in Children and Adolescents PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Our aim was to describe the development and usability of a mobile device-based game therapy software for ADHD. |
ZHENGKUI LIU; | 2023-03-01 |
| 127 | A Phase 4, Randomized, Double-Blind, Multicenter, Placebo-Controlled, Parallel-Group Study of The Efficacy and Safety of SPN-812 in Preschool-Age Children (4 to 5 Years Old) With Attention-Deficit/Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the efficacy and safety of SPN-812 (viloxazine extended release) in children 4 to 5 years of age with ADHD. |
SUPERNUS PHARMACEUTICALS | 2023-03-01 |
| 128 | A Group Training to Plan and Organize for Adolescents With ADHD: Effectiveness and Feasibility PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This observational study is a first orientation on the effects and feasibility of a group training to plan and organize for adolescents with ADHD. This study focuses on the following questions: – Is there an improvement on planning skills after training? – Are there fewer ADHD characteristics after training? – Is there an improvement on self-esteem after training? – How feasible is a group training for adolescents with ADHD? – How satisfied are practitioners and adolescents about the training? Based on the effect-size of the individual training variant, … |
MANON VAN HENSBERGEN; | 2023-03-01 |
| 129 | Prevalence of DAO (diamino Oxidase) Deficiency in Newborns PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Observational study to estimate the prevalence of genetic DAO deficiency in the population. |
AB BIOTEK | 2023-02-28 |
| 130 | Neurofeedback-Based Digital Therapeutics for The Diagnosis and Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Children PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: A multi-center, randomized controlled trial is being conducted to investigate the efficacy of a novel digital therapeutics (DTx) program that utilizes a cross-training approach between neurofeedback training and executive function training for pediatric patients (aged 6-12) diagnosed with ADHD. This gamified interactive program is designed to improve attention deficits and executive function impairments in pediatric patients with ADHD. It is delivered through an engaging iPad game in a home-based treatment format. Patients will be randomly assigned to one of three groups: medication alone, digital therapeutics alone, … |
LEI LEI; | 2023-02-24 |
| 131 | Effectiveness of Social Virtual-reality on Enhancing Social Interaction Skills in Children With Attention-deficit/Hyperactivity Disorder: A Three-arm Pilot Randomised Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study targets children with diagnosed ADHD and aims to (1) develop a social virtual reality-based intervention, (2) investigate its effects on improving the social skills and executive functioning of inhibitions, … |
JING QIN; | 2023-02-18 |
| 132 | Cortical Contributions to Frequency-Following Response Generation and Modulation; Post-Operative Outcomes PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to better understand cortical contributions of the human temporal lobe to the frequency-following response. Frequency-following responses (FFR) are electrophysiological recordings that reflect phase-locked activity of neural ensembles in the auditory pathway and are used as an indicator of the integrity of supra-threshold speech processing. FFR was first studied in subcortical areas, … |
TAYLOR ABEL; | 2023-02-14 |
| 133 | A Randomized Controlled Intervention Study to Assess A Wearable Digital Therapy for Youth With ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate and compare three different investigational wearable digital interventions to determine if they are helpful for improving symptoms and functioning in children diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD). |
REVIBE TECHNOLOGIES | 2023-02-13 |
| 134 | The Effect of Physical Activity on The Response of Autonomic Nervous System in Individuals With Autism Spectrum Disorders of Different Age Groups PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will investigate the effect of physical activity on autism spectrum disorder (ASD) in individuals with ASD of different age groups through measuring the hemodynamic, heart activity and respiratory system parameters. |
MOHAMMED MOUSTAFA; | 2023-02-12 |
| 135 | Connecting Breath and Mind: Development of An Online Holistic Treatment Programme Connecting Psychological Wellbeing and Breathing Techniques in Children and Young People With Long COVID PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Recruitment target: Phase I: Co-design of intervention: 5 to 15 CYP aged between 12-18 years of age referred to the pan-London long COVID MDT. Phase II: Randomised pilot: 40 patients (12-18 years) will be recruited from a potential pool of 214 patients referred to the pan-London long COVID MDT. Methods: Phase I: Co-design Design and setting The intervention will be co-designed with CYP following a process informed by practice-base evidence, which centres the voices and wisdom of CYP, focuses on creativity and playfulness, … |
ROYAL BROMPTON & HAREFIELD NHS FOUNDATION TRUST | 2023-02-03 |
| 136 | The Effectiveness of Cognitive-Functional Intervention to Reduce Driving Risk Factors of Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Attention deficit hyperactivity disorder (ADHD) is associated with a high risk for driving accidents. Adolescents with ADHD are 1.2 to 4 times more prone to be involved in car accidents. Driving accidents are the leading cause of death among adolescents. Objective: Examining a multidimensional applied intervention based on serious gaming principles to improve the driving capabilities and skills of adolescents with ADHD Methodology: The study will include 90 adolescents (aged 15-18 years old) with ADHD diagnosis who did not yet start driving lessons. Participants will undergo a stratified randomized clinical trial, single-blinded. The stratified randomization process will include gender, … |
NAVAH RATZON; | 2023-02-02 |
| 137 | Effect of Ayres Sensory Integration Therapy on Sensory, Motor, Cognitive, Behavioral Skills and Social Participation in Children With Attention Deficit Hyperactivity Disorder: Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) is a very common neurodevelopmental disorder in childhood characterized by short attention span, impulsivity and hyperactivity. It is also known that sensory integration problems are seen together with the basic symptoms of ADHD. Studies indicate that children with ADHD have difficulties in perceiving and processing sensory stimuli, and in relation to this, they have difficulty in producing appropriate sensory responses at school, at home and in social environments. However, it was observed that the interventions related to ADHD did not focus on the sensory-motor dimension enough, … |
BUSRA KAPLAN; | 2023-02-01 |
| 138 | Using Transcranial Alternating Current Stimulation With Starstim Home Device to Improve Executive Function in Youths With 22q11.2 Deletion Syndrome: A Randomized Double-blind Sham-controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion. The main aim of the present research project is to investigate the effects of repeated, individually tuned high-density (HD) tACS on cognition (i.e., WM performance) and related neuroimaging markers in carriers of the 22q11DS. As cognitive deficits, most notably WM impairment, are among the earliest signs of psychotic disorders, interventions during adolescence aimed at reducing cognitive decline in at-risk individuals may prove effective in delaying or even preventing the later emergence of psychotic symptoms. |
STEPHAN ELIEZ; | 2023-02-01 |
| 139 | A Randomized Controlled Trial of Internet-based Cognitive Behavioral Therapy for Adult Attention Deficit Hyperactivity Disorder in Sweden PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit hyperactivity disorder (ADHD) is a disorder characterized by lack of attention, hyperactivity, and impulsivity. It can have major impact on everyday life and result in negative consequences for one’s personal, academic, and work situation. For individuals with symptoms of ADHD, increased levels of anxiety and depression are common, and an overall reduction of quality of life is often present. This study protocol describes a clinical trial of internet-based cognitive behavioral therapy (iCBT), using a randomized controlled study design, with the primary aim to increase quality of life, as well as to reduce symptoms of ADHD, anxiety, depression, … |
ALEXANDER ROZENTAL; | 2023-01-25 |
| 140 | Emotion Regulation Training for Adolescents With ADHD Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this single-case study is to pilot and evaluate a new psychological intervention (SKILLS-ER) targeting emotion regulation in adolescents with ADHD. Participants (n=9; 13-18 years of age) and their parents will partake in the intervention consisting of a total of eight sessions. |
JOHAN ISAKSSON; | 2023-01-23 |
| 141 | The Effect of Reward on Cognitive Functioning, Motor Skills, and Motivation in 8- to 10-Year-Old Children With Attention-Deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This interventional study aimed to aimed to evaluate the effects of rewards on cognitive function, motor skills, and motivation in 8- to 10-year-old children with ADHD following 3- and 6-week interventions. |
VILMA DUDONIENE; | 2023-01-15 |
| 142 | Effect of Stimulant Medication on Loss of Control Eating in Youth With Attention Deficit/Hyperactivity Disorder: A Prospective, Observational Case Series PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Loss of control eating (LOC-E) in youth predicts the later development of full syndrome eating disorders, such as binge-eating disorder (BED), and therefore, could be a relevant target for prevention interventions. Children with attention deficit/hyperactivity disorder (ADHD) are at higher risk of experiencing LOC-E than healthy controls, and there is evidence that related neurocognitive predisposing factors, such as impulsivity and dysfunctional reward processing, are associated with the pathogenesis of LOC-E. Therefore, … |
AARON KESHEN; | 2023-01-11 |
| 143 | Promoting Communicative Initiative in Minimally Verbal Autistic Children Through Interaction with The Humanoid Social Robot PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Minimally verbal (MV) children with Autism Spectrum Disorder (ASD) face significant challenges in communication and social interaction, which are fundamental to learning and development. Current therapeutic approaches, such as speech therapy and augmentative communication systems, often have variable efficacy due to engagement and responsiveness challenges. This pilot study investigates using of the humanoid robot NAO as part of a rehabilitative program designed for MV children with ASD. NAO, with its predictable and engaging interaction style, is hypothesized to enhance communicative initiative, expressive communication, and social interaction in this population. The study employs a randomized controlled trial design, … |
FRANCESCA CUCINOTTA; | 2023-01-02 |
| 144 | Advancing Understanding, Diagnosis and Monitoring of Thyroid Hormone Action Defects (ADAM-THAD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this observational study is to learn about the neurological and cardiological phenotype of patients with resistance to thyroid hormone (RTH) syndromes beta and alpha (RTHß and RTHa) due to dominant negative variants in the genes encoding the thyroid hormone receptors alpha (THRA) and beta (THRB). The main question[s] it aims to answer are: – Define frequency and improve early diagnosis for RTH syndromes – Developing tools to accelerate diagnosis of RTH syndromes – Development and validation of monitoring tools Participants, … |
ISTITUTO AUXOLOGICO ITALIANO | 2023-01-01 |
| 145 | Clinical Trial to Evaluate The Safety and Efficacy of NRCT-101SR in Adult Attention Deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to evaluate the efficacy and safety of NRCT-101SR compared to placebo in adult patients with ADHD aged 18 years and older. |
ANN CHILDRESS; | 2023-01-01 |
| 146 | Quantitative EEG Neurofeedback As An Add-on Therapy For Attention-deficit Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit/hyperactivity disorder (ADHD) is a common neurological disorder in children, mainly manifesting as attention deficit, excessive hyperactivity, and impulsivity. It is a chronic condition that affects millions of children and often continues into adulthood. The prevalence of ADHD in the worldwide is approximately 5%, predominantly occurring in boys, and more than half of patients continue to experience symptoms into adulthood. Children with ADHD have moral disorders and learning difficulties, and these factors will seriously affect their academic achievements and familial and social relationships; thus, treatment is necessary. Currently, the treatment for ADHD is usually pharmacological intervention, such as methylphenidate, … |
MOHAMED EMAD ELDEEN MAHMOUD; | 2023-01-01 |
| 147 | Dialectical Behavioral Therapy Skills for Impulsive Aggression in Children Diagnosed With Attention Deficit Hyperactivity Disorder at Alexandria University Hospitals PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This trial aims to Study the efficacy of DBT skills for impulsive aggression and executive dysfunctions in drug naïve children who are presented with impulsive aggression and ADHD and attending Child and adolescent clinic at Alexandria university hospitals using weekly group therapy for at least 10 month and testing pre and posttreatment biomarkers of aggression. |
AYA MAGED; | 2023-01-01 |
| 148 | Biomarkers of ADHD Treatment Response PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this translational biomarker study is to use electroencephalography (EEG) to identify brain signatures that will predict a child’s response to two of the most commonly prescribed ADHD medications, … |
ANNE ARNETT; | 2023-01-01 |
| 149 | A Phase 3, Dose-Optimized, Randomized, Double-Blind, Placebo-Controlled, Single-Center, Parallel Efficacy and Safety Laboratory Classroom Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD) Using CTx-1301 (Dexmethylphenidate) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to evaluate the efficacy and safety of CTx-1301 in adults with ADHD in a laboratory classroom setting. |
ANN CHILDRESS; | 2022-12-29 |
| 150 | Assesment of TDApp2 An EHelath Tool to Make Pharmacologic and Non-pharmacologic Treatment Recommendations for Patients With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to compare the recommendations made by TDApp2 with those by relevant clinical practice guidelines in children/adolescents with ADHD. |
XAVIER CASTELLS; | 2022-12-12 |
| 151 | A Pilot Study of A Blended Intervention Targeting Emotion Dysregulation in Adults with ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The current study aims to investigate the feasibility and preliminary clinical effects of a blended psychological intervention targeting emotion dysregulation in adults with ADHD. |
ASTRI LUNDERVOLD; | 2022-11-29 |
| 152 | Effectiveness of Social Virtual Reality Based Intervention on Enhancing Social Interaction Skills in Children With Attention-deficit/Hyperactivity Disorder: A Pilot Randomised Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study targets children with diagnosed ADHD and aims to (1) develop a social virtual reality based (SocVR) intervention and (2) investigate its effects on improving the social skills and executive functioning of inhibitions, emotional control and attention of the children compared to traditional social skills training. The study will be a three-arm parallel randomised controlled trial comparing the effects of a SocVR with traditional social skills training on social skills and executive functioning of children with ADHD. The study period is 2 months, including 4 weeks (2 sessions per week) of intervention and control, … |
WONG PORTIA; | 2022-11-15 |
| 153 | Psychometric Testing: Cued Vs. Learned Suppression PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: In this line of research, the researchers are examining whether performance on a cued attentional suppression (ignoring) task is related to performance on a learned attentional suppression task. In addition, these measures are related to the capacity of working memory and every day inattentive traits. |
NANCY CARLISLE; | 2022-11-02 |
| 154 | FAACTS: Feasibility/Acceptability of Attentional-Control Training in Survivors PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a multicenter pilot randomized controlled trial, with an active control condition, of the feasibility, acceptability, and preliminary efficacy of EndeavorRx in a cohort of survivors of acute lymphoblastic leukemia or brain tumor ages 8-16 who are > 1 year from the end of therapy. |
STEVEN J. HARDY; | 2022-11-01 |
| 155 | Prevalence Study of Genetic DAO Deficiency and Lower Urinary Tract Symptoms PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to determinate the prevalence os genetic DAO deficiency in patients with lower urinary tract symptoms. |
JOSÉ LUIS PONCE DÍAZ-REIXA; | 2022-10-11 |
| 156 | Resilience As A Mediator Between Adverse Life Events and Emotional Behavioral Problems in Children and Adolescents and Comparison Between Individuals With Attention-Deficit /Hyperactive Disorder and Controls PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: To explore if resilience serves as a mediator between adverse life events and emotional and behavioral problems, and compare the difference of resilience and its mediating effects between children and adolescents with and without ADHD. |
CHANG GUNG MEMORIAL HOSPITAL | 2022-10-01 |
| 157 | Measuring Glutamate and GABA Brain Levels in Adults With Attention Deficit Hyperactivity Disorder (ADHD) Using Magnetic Resonance Spectroscopy (MRS) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neurobiological brain disorders. Diagnosis of ADHD in adults is complex and subjective. Recent studies give further support for the involvement of glutamatergic and GABAergic neurotransmitters in the pathophysiology of ADHD. Studies show that glutamate (Glu) and GABA change according to stimulant treatment. Measuring modulations in the anterior cingulate cortex (ACC) of Glu and GABA may help to explore the pathophysiology of ADHD and give a diagnostic biomarker tool for ADHD in adults. Aim: To characterize Glu and GABA levels in the ACC, … |
WEIZMANN INSTITUTE OF SCIENCE | 2022-10-01 |
| 158 | Effectiveness and Security Testing of A Mobile App (B·RIGHT) for Adolescents With Attention-Deficit/Hyperactivity Disorder and Emotion Dysregulation PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To assess the effectiveness and security of a mobile App (beta version) for self-managing emotion dysregulation in a pragmatic randomized controlled trial with 80 adolescents with attention-deficit/hyperactivity disorder comparing 40 patients with treatment as usual (TAU) with 40 patients with TAU plus the mobile App |
CONSORCI SANITARI DEL MARESME | 2022-10-01 |
| 159 | Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Children with sickle cell disease (SCD) exhibit significantly reduced cognitive functioning (often difficulties with attention) compared to peers and siblings without SCD. EndeavorRx (Akili Interactive Labs: Boston, MA) is an FDA-approved home-based, electronic attentional-control training program designed to treat attention problems in youth. Users access EndeavorRx on a tablet device for 25-30 minutes each day, 5 days per week, for 4 weeks. The program involves training in a game-like environment that repeatedly challenges attentional-control abilities and adapts to user performance, becoming more difficult over time as performance improves. This pilot study is examining the feasibility, acceptability, … |
STEVEN J. HARDY; | 2022-10-01 |
| 160 | Investigating Electroencephalographic Predictors of Default Mode Network Anticorrelation for Personalized Neurofeedback PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Healthy adult subjects will participate in two sessions. The first session will involve measurements of brain activity using simultaneous recordings with electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI). During brain activity measurement, participants will perform cognitive tasks assessing attention. The second will involve fMRI-based neurofeedback during simultaneous EEG-fMRI recording. Participants will receive real-time visual feedback of signals measured from specific parts of their brain and will try to control that activity. |
DREXEL UNIVERSITY | 2022-10-01 |
| 161 | An Observational Study of The Developing Brain, Impulsivity and Compulsivity PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Impulsivity is acting ‘without thinking.’ Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are. Extreme versions of these behaviors play a role in mental disorders. Researchers want to study changes in the brain to learn more about these behaviors. Differences in genes may also play a role. Objective: To learn about genetic \& brain features that explain why levels of impulsivity and compulsivity vary across people. Eligibility: People ages 6 – … |
TONYA J WHITE; | 2022-09-30 |
| 162 | Managing Young People With Attention Deficit Hyperactivity Disorder in Primary Care (MAP) Study: Mapping Current Practice and Co-producing Guidance to Improve Healthcare in An Underserved Population PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Attention deficit hyperactivity disorder (ADHD) is the most common childhood neurodevelopmental disorder. It affects around 5% of children and adolescents, and up to 40% continue to experience symptoms into adulthood. Primary care practitioners (e.g., general practitioners (GPs), nurses, link workers, clinical pharmacists) play an important role in the healthcare of young people (YP) with ADHD, particularly due to long waiting times in adult mental health services, and patchy provision of specialist services. However, … |
ANNA PRICE; | 2022-09-28 |
| 163 | Promoting Implementation of Behavioral Classroom Interventions for Children With ADHD in Urban Schools: A Pilot Test, Aim 3 PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to pilot test for feasibility and initial promise an implementation strategy resource package that aims to support teachers in using behavioral classroom management interventions for children with hyperactive, inattentive, or impulsive behaviors. Participating teachers will be randomized to receive the resource package or support as usual and the research team will examine, a) teacher implementation of behavioral classroom interventions and b) mental health outcomes for enrolled children. |
GWENDOLYN M LAWSON; | 2022-09-20 |
| 164 | Digital-based Psychosocial Intervention for Parents of Children With Neurodevelopmental Disorders: A Randomized Control Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this clinical trial is to implement a structured psychosocial intervention program with digital support (randomized and with a control group) that will be conducted virtually and synchronously to families of children with autism spectrum disorder (ASD) and families of children with Attention Deficit with hyperactivity Disorder (ADHD). The main questions it aims to answer are: 1. Will the program impact on different variables in the parents’ domain (parental stress variables, quality of life/social support and coping skills), 2. Will the program impact on different variables in the children’s domain (daily life functioning, social behavioral variables, … |
CARMEN BERENGUER-FORNER; | 2022-09-07 |
| 165 | Multiple Family Narrative Therapy As Treatment for Chinese Families of Children With Attention-Deficit/Hyperactivity Disorder: A Randomised Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this randomized controlled trial is to develop and to implement a multiple family narrative therapy intervention consisting of parent-child relationships training among Chinese families of children with attention deficit hyperactivity disorder (ADHD). The intervention aims to reduce the psychological distress of parents and their child, thus improving parent-child relationships, and the trial aims to assess the effectiveness of MFNT among them. A RCT design supplemented by qualitative interviews will be used to evaluate the effectiveness of multiple family narrative therapy intervention on family welfare. |
TAK MAU CHAN; | 2022-09-01 |
| 166 | Abnormal Thyroid Profile in Children With Attention Deficit With Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Rationale: The observational data of University Children’s Hospitals of Nice, suggest that about a quarter of children and adolescents with ADHD may present with an abnormal thyroid profile. Main objective: To confirm that a subsample of children and adolescents with ADHD present with an abnormal thyroid profile using the gold standard for free fraction of hormones : chromatography with mass spectrometry. Secondary objective: To examine to what extent this categorization holds using classic immuno-analytic assays. To characterize clinically and from a neuropsychological point of view this subsample and compare it to the other participants. Study duration and design: 30 months (24 months for inclusion and 6 months for data analyses) open-label, (category 2 : interventional research with minimal risks or constraints), multicentre, without treatment or placebo administration. Expected outcomes: Ancillary studies will investigate genetic physiopathological mechanisms (polymorphisms of deiodase or transmembrane carriers of thyroid hormones) and link this profile to other biological markers proposed in the literature (low ferritinemia, higher oxidative stress, atopic comorbid disease). The clinical trajectory of this subgroup and the persistence of this abnormal thyroid profile in adulthood will be a relevant issue in the future. |
HERVÉ CACI; | 2022-09-01 |
| 167 | Refinement and Testing of A New Cognitive-Behavioral Intervention to Treat Executive Dysfunction in College Students With Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: College students with ADHD have significant difficulty effectively managing their time, organizing, planning, and completing their academic work. As a result, they typically have lower grade-point averages, more course failures and withdrawals, are more likely to be placed on academic probation and are less likely to graduate from college than students without ADHD. The purpose of this project is to refine and test a psychological intervention on campus to help students with ADHD develop these self-management skills so that they can be more successful in college and avoid these negative outcomes. |
MARY V. SOLANTO; | 2022-09-01 |
| 168 | Effects of Individualized Fairytales on Preschool Children With Attention Deficit Hyperactivity Disorder With Developmental Delay PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Under traditional rehabilitation programs, investigate the additional effects of individualized fairytales on preschool children with Attention Deficit Hyperactivity Disorder with developmental delays. |
RU-LAN HSIEH; | 2022-08-20 |
| 169 | Effects of General Anesthesia on Brain Functional Connectivity and Cognition in Children With Potential Neurological Damage PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Postoperative Cognitive Dysfunction(POCD)is a common postoperative complications, existing clinical research focused on the adult patients, ignoring that the developing human brain with underlying neurological impairments may be at higher risk for cognitive impairment, so we need a prospective study, observe this kind of special groups in the brain structure and function of before and after general anesthesia, To determine the susceptibility to neurotoxicity of general anesthesia drugs. |
LAI JIANG; | 2022-08-15 |
| 170 | A Pilot Study on Application of Online Technology for Mindfulness-based Intervention on Parents of Children With Attention Deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This project apply curriculum of online programme materials and structure for mindful parenting and caregiving. It will include four modules (introductory mindfulness, mindful parenting, applying mindfulness in challenging moments, and advanced exercises for parents of children with special needs). Each module will include short psychoeducation videos and audio mindfulness exercises that can be used in various web-based or application-based platforms. A set of videos and audio exercises will be produced for the core program materials. One study of online mindful parenting program reported a low completion rate below 30% (Boekhorst et al., 2021), … |
HERMAN HAY MING LO; | 2022-08-15 |
| 171 | Investigation of The Effect of Telerehabilitation-Based Exercise and Motor Imagery Training on ADHD Symptoms, and Balance in Children With ADHD: A Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders with heterogeneous clinical features such as inattention, hyperactivity, and impulsivity. It has been shown that one-third of children with ADHD have problems with tasks that require fine and gross motor skills. In addition, … |
NURULLAH BUKER; | 2022-08-15 |
| 172 | Analysis of Risk Factors of Neurodevelopmental Disorder in Deaf Infants Under Ten Months of Age PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Among risk factors of neurodevelopmental disorder is congenital hearing loss. However, congenital deafness is neither necessary nor sufficient for the occurrence of warning signs of neurodevelopmental disorder. The investigative team hypothesizes that the co-occurrence of these two clinical entities results from a common origin, within a syndromic diagnosis including other medical issues. These situations would therefore be very different from those of babies suffering from isolated sensorineural deafness. This study aims to identify which factors are statistically correlated with the association of congenital deafness and early symptoms of neurodevelopmental disorder, … |
SALOMÉ AKRICH; | 2022-08-03 |
| 173 | Feasibility and Acceptability Study of A Powdered Multinutrient Formula in Children With Attention-Deficit/Hyperactivity Disorder and Emotional Dysregulation PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study aims to test the feasibility and acceptability of 1) consumption of EMPowerplus Lightning Sticks, 2) at-home collection of blood and urine samples, and 3) remote visits and completion of online behavioral questionnaires. |
JEANETTE JOHNSTONE; | 2022-08-01 |
| 174 | Executive Function Enhanced Parent-Based Treatment for Children with ADHD and Overweight or Obesity PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The pilot study will be a one group open-label treatment program and will be used to refine a parent-based behavioral treatment enhanced with executive-function training (PBT-EF) for children with comorbid overweight or obesity and Attention-Deficit Hyperactivity Disorder (ADHD). |
DAWN EICHEN; | 2022-07-26 |
| 175 | A Randomized Clinical Trial to Assess The Effectiveness and Safety of Digital Therapy for Treating Attention Deficit Hyperactivity Disorder in Children PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is designed to explore the effect of Multitask game-based digital therapy versus Schulte Grid digital game on attentional functioning (measured by the TOVA), ADHD symptoms, executive functioning, and clinical impairment, in children diagnosed with ADHD. Investigators will also evaluate the safety of digital therapy for intervention treatment of childhood attention deficit hyperactivity disorder. |
CHILDREN’S HOSPITAL OF FUDAN UNIVERSITY | 2022-07-16 |
| 176 | BUILT Family Lifestyle Program for Children with ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators have developed BUILT in hopes of empowering families to adopt and sustain healthy food, sleep, and exercise routines that optimize child focus, attention, and behavior. Over 6-weeks, the BUILT program will explore what science says about the effects of sleep, nutrition, and exercise on brain development and behavior; investigate the food, sleep, and exercise routines of the world’s best athletes and intellectuals; and experiment with home routines to find those that best fits with participating families. It is hypothesized that families participating in BUILT (N=150) will show significant improvements in child health behaviors (sleep, nutrition, physical activity, … |
EDUARDO E. BUSTAMANTE; | 2022-07-15 |
| 177 | ADHD Remote Technology Study of Cardiometabolic Risk Factors and Medication Adherence (‘ART-CARMA’) PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder, with a prevalence among adults of 2.5%. The disorder is diagnosed based on impairing levels of inattentive, hyperactive and impulsive behaviours. Most adults with ADHD present with additional mental health problems. Adults with ADHD have an increased risk to develop so-called cardiometabolic illnesses, such as type-2 diabetes, obesity and cardiovascular disease (e.g., heart failure). However, detailed knowledge about the screening, … |
JONNA KUNTSI; | 2022-07-12 |
| 178 | A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Determine The Efficacy and Safety of Once Daily Centanafadine Capsules for The Treatment of Children With Attention-deficit/Hyperactivity Disorder (ADHD) PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This trial will be conducted to evaluate the efficacy of centanafadine QD XR versus placebo in the treatment of child subjects (4 to 12 years, inclusive) with ADHD. The trial will consist of a screening period, a double-blind treatment period, and follow-up period. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2022-07-11 |
| 179 | Compatibility of Participation Levels of Adolescents With Attention Deficit and Hyperactivity Disorder in Terms of Adolescent and Parent Perspectives PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this study is to assess the agreement between the outcomes of adolescents with attention deficit hyperactivity disorder (ADHD) who participated in Participation and Environment Measurement Child & Youth (PEM-CY) by the adolescent and primary caregiver. There are a few studies in the literature that look at the participation of teenagers with ADHD, but none that look at the participation of adolescents with ADHD from both the perspective of the adolescents and the primary caregivers. The primary caregiver’s measurement results and the adolescents’ measurements do not concur, according to this study’s hypothesis. |
OZGUN KAYA KARA; | 2022-07-01 |
| 180 | A Collaborative Treatment Network for Youth With or at High Risk for Bipolar Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN). CBN sites have expertise in diagnosing, assessing, and treating BSDs in youth. The primary aims of this study are to (1) identify and reliably diagnose youth (ages 9 to 19 yrs) with full bipolar disorder (BD) and BSDs, and (2) examine predictors (e.g., mood instability, … |
DAVID J. MIKLOWITZ; | 2022-07-01 |
| 181 | Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators are investigating whether home-based tDCS over the course of four weeks can improve ADHD symptom severity and improve dysexecutive functioning (cognitive control). Further, the investigators are investigating whether there is a dose-dependent response to tDCS. |
JOAN A CAMPRODON; | 2022-07-01 |
| 182 | Treatment of COVID-19 Post-acute Cognitive Impairment Sequelae (PASC) With Portable Brain Stimulation: A Double-blind, Randomized-controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: After almost 2 years of pandemic, the consequences of the post-COVID syndrome, or PASC (Post Acute-Sequelae of Sars-CoV-2), have become a major challenge in the management of affected patients, generating costs for health services. and insecurity regarding treatments for the sequelae, given the complex and still poorly understood pathophysiology of COVID-19. This troubling scenario raises important questions about the impact of COVID-19 on central nervous system sequelae, including the risk of cognitive decline in old age and progression to dementia. Therefore, … |
ANDRE R BRUNONI; | 2022-06-30 |
| 183 | Sensitivity of Children With Attention Deficit/Hyperactivity Disorder to Memory Error Production PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of the study is to test whether children with Attention Deficit/Hyperactivity Disorder (ADHD) are more susceptible to false memory production using a DRM paradigm. The number of critical decoy production errors will be analyzed and compared to the calibration of the test. |
PIERRE MARTIN; | 2022-06-28 |
| 184 | Effectiveness of Prosocial-orientated Acceptance and Commitment Training (PACT) Programme for Parents of Children With Special Health Care Needs in Response to Outbreaks of Novel Infectious Disease: A Randomised Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This randomised controlled trial aims to determine the efficacy of a 12-week, smartphone-based Prosocial-orientated Acceptance and Commitment Training (PACT) programme plus age-appropriate positive parenting advice on the psychological flexibility, prosociality, parenting competence and family functioning with parents of children with special health care needs as well as the mental well-being of parent-child dyads over 12 months follow-up. |
YUEN YU CHONG; | 2022-06-27 |
| 185 | TBS Treatment for Treatment-Resistant Depression: A Randomized, Sham-Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Depression is a highly disabling disease that is prevalent throughout the world. The treatments proposed and studied to date have shown to be partially effective in treating this condition. Neuromodulation strategies have been used as an alternative, especially for refractory and challenging cases. In this context, studies investigating the effectiveness of transcranial magnetic stimulation, including the theta burst stimulation (TBS) modality, have been increasing in number. However, there is still a lack of information seeking to explore the maximum effectiveness in the TBS modality. Therefore, the investigators developed a new stimulation protocol consisting of 3 TBS sessions per day, … |
ANDRE R BRUNONI; | 2022-06-06 |
| 186 | A Peer-Delivered High School Preparatory Intervention for Students With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will test whether a peer-delivered intervention for high school students with ADHD outperforms enhanced school services as usual. Ninth grade students with ADHD (N=72) will be randomly assigned to the intervention (summer STRIPES) or the enhanced school services control group (SSU plus). Students will be assessed in the spring of 8th grade, fall of ninth grade, and spring of ninth grade. Primary outcomes will be GPA, Class Attendance, Disciplinary Incidents, and ADHD symptoms (parent and teacher report). |
MARGARET SIBLEY; | 2022-06-03 |
| 187 | The Relationship Between Brain Volume and Sensory Integration in Children and Adolescence With Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The relationship between brain volume and sensory integration in children and adolescence with attention deficit hyperactivity disorder and autistic spectrum disorder; comparative study |
AMIRA MOHEB; | 2022-06-01 |
| 188 | The Relation Between Attentional, Sensory and Emotional Dysregulation in Adults With Posttraumatic Stress Disorder: A Double-blind, Placebo-controlled Randomized Controlled Trial of The Combined Treatment With Reboxetine and Methylphenidate PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Up-to-date, no studies have examined the attentional, sensory and emotional processing (difficulties) among patients diagnosed with Posttraumatic Stress Disorder (PTSD). In addition, the efficiency of drug treatments that focus on the noradrenergic and dopaminergic, and thus influence attention processing and PTSD symptoms through these pathways, have only briefly been investigated. There is well-established and long-standing evidence for the involvement of dopamine and noradrenaline in attentional function. This previously led to an investigation by the investigator’s research lab in which the investigators hypothesized the involvement of an attentional disorder would influence PTSD symptoms in a rat model. Based on these results, … |
AVI AVITAL; | 2022-06-01 |
| 189 | Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original in Child With Attention-deficit-hyperactive Disorders PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a cross-over trial, design to determine the efficacy and safety of generic and original prolong-release methylphenidate (PR-MPH) in children with ADHD who had received immediate-release methylphenidate treatment |
CHANATTHIDA MUANGKUM; | 2022-06-01 |
| 190 | The Effectiveness of Mindfulness-based Stress Reduction (MBSR) Programme for Parents of Children With ADHD: A Pilot Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study aimed at comparing the effects of 8-week MBSR programme intervention group with usual care group in reducing parental stress and improving quality of life of parents of children with ADHD in Chinese culture. |
YIM WAH MAK; | 2022-06-01 |
| 191 | Evaluating The Efficacy and Safety of Transcranial Pulse Stimulation on Young Adolescents with Attention-Deficit-Hyperactivity Disorder- A Pilot Randomized, Double-blinded, Sham-controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is the first nationwide study using Transcranial Pulse Stimulation to evaluate its efficacy and safety on 30 young adolescents with ADHD. Six verum/ shamTPS sessions will be delivered to all subjects on a 1: 1 ratio, balanced by gender and age. Attention deficit, hyperactivity, impulsivity, and oppositional defiance will be the primary outcome. Secondary outcomes include ADHD severity, frequency of inattention, hyperactivity, impulsivity, executive function and neural connectivity changes via neuroimaging. Results emerging from this study will generate new knowledge to ascertain whether TPS can be used as a top-on treatment in ADHD. |
TERIS CHEUNG; | 2022-06-01 |
| 192 | A Pilot Study to Evaluate The Effects of Atomoxetine on Impulsivity in Patients With Tourette’s Syndrome PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this pilot study is to evaluate the effects of Atomoxetine, a selective noradrenaline reuptake inhibitor, on impulsivity in patients with Tourette’s syndrome. |
POITIERS UNIVERSITY HOSPITAL | 2022-05-31 |
| 193 | Neurofeedback Based on Near-infrared Spectroscopy As A Therapy for Food Addiction in Obese Subjects PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus promoting a long-term weight loss in obese subjects. Patients will be trained during a month with 8 NF sessions and results based on clinical data and different questionnaires results will be compared between inclusion and 3 months later |
RONAN THIBAULT; | 2022-05-25 |
| 194 | Research and Promotion of Systematic Aerobic Exercise and Intelligent Monitoring System in Executive Skill Training for School-aged Children With Attention Deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Around 7.2% of children around the world are suffering from Attention Deficit Hyperactivity Disorder (ADHD). Systematic executive skill training for children is currently recognized as one of the main programs for psychosocial behavioral interventions in ADHD, but the theoretical basis for the 1 hour play class component of the 3 hours per week children’s classroom is insufficient. We have developed a closed-loop moderate-intensity aerobic training system, which is combined with an intelligent monitoring system, … |
CHEN LI; | 2022-05-24 |
| 195 | Preliminary Feasibility and Clinical Effectiveness of A Single-Session Intervention on The Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1 PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Children with neurofibromatosis are more likely to have difficulties related to their psychological and neurocognitive functioning (e.g., more likely to have depression, have social difficulties, be diagnosed with ADHD). The purpose of this randomized control study is to determine how effective and useful this study’s single session intervention can be in improving psychological and neurocognitive functioning. Enrolled families will consist of one parent/guardian and child. Parents and patients will complete questionnaires and objective tests at baseline, 3 months, … |
JENNIFER M ROHAN; | 2022-05-12 |
| 196 | Guided ADHD Therapy for Managing The Extent and Severity of Symptoms – A Randomized, Controlled, Parallel-group, Intervention Study to Assess An At-home, Game-based Digital Therapy for Treating Adult Patients With Attention-Deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The objective of this study is to assess the safety and effectiveness of an at-home, game-based digital therapy for treating adult patients with Attention-Deficit/Hyperactivity Disorder (ADHD). |
ANN CHILDRESS; | 2022-05-05 |
| 197 | What Are The Long-Term Effects of Cognitive-Behavioural Therapy on Quality of Life in Adult Patients With ADHD? PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: Background and objective: Although the short-term effects of cognitive behavioural therapy (CBT) in adult patients with ADHD are established, not a lot is known about longer-term effects. To assess the additive value of CBT to pharmacotherapy in the long term, an assessment of ADHD symptoms and quality of life in patients that followed CBT four to eight years ago is done. To understand how CBT impacts quality of life in patients, an assessment of self-efficacy and self-esteem is made. Furthermore, … |
R.K.R.W. WETTSTEIN; | 2022-05-01 |
| 198 | Randomized Study Of Novel Enuresis Alarm (GoGoband® )Vs Standard Nocturnal Enuresis Alarm (SNEA) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Identify the dry night rate in patients using the GoGoband® nocturnal enuresis device vs a standard Pflaundler bedwetting alarm. |
ISRAEL FRANCO; | 2022-04-29 |
| 199 | Do Fidget Instruments Enhance Attentional Control and Comprehension in 6-13 Year-olds With Attention Deficit Hyperactivity Disorder (ADHD)? PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Purpose: The purpose of this study is to investigate the usage of fidget technology and its effects on attention, working memory, and comprehension in children ages 6-13 with Attention Deficit Hyperactivity Disorder (ADHD). This study aims to examine the implications of fidget usage 2 different measures of attention; attentional control (working memory domain) and comprehension (recall, encoding, and recognition). Participants: 6-13 year-old clients at 3-C Family Services, a private mental health clinic in Cary, NC, with a diagnosis of ADHD (Inattentive, Hyperactive, … |
JENNIFER R PERSIA; | 2022-04-18 |
| 200 | Investigation of The Effect of Yoga on Balance, Reaction Time and Agility in Children With Attention Deficit and Hyperactivity Disorder: A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Purpose: To determine the effect of 8-week kids yoga training on balance, reaction time and agility on children diagnosed with attention deficit hyperactivity disorder (ADHD). Method: A randomized controlled trial. The intervention (kids yoga) was an 8-week program administered to children attending a special education center by a yoga instructor occupational therapist. Outcomes included Pediatric Balance Scale, Bruininks-Oseretsky Motor Proficiency Test-Short Form, and Microgate Witty SEM System assessed at baseline and at the end of 8th week. |
CEMRE BAFRALI; | 2022-04-15 |
| 201 | A Phase II Tolerability and Efficacy Study of PDC-1421 Treatment in Adult Patients With Attention-Deficit Hyperactivity Disorder (ADHD), Part II PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Part II is a double-blind, randomized, parallel-group, placebo-controlled study. The primary objective of this trial is to determine the effective doses and treatment period of PDC-1421 Capsule in subjects with ADHD. The secondary objective is to evaluate the safety of PDC-1421 Capsule in subjects receiving PDC-1421 at various dose levels. |
KEITH MCBURNETT; | 2022-04-07 |
| 202 | A Pilot Study to Assess The Efficacy and Safety of A Novel Device (VIZO Glasses) in The Management of ADHD in Adults PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a 2-months study, where eligible ADHD adult participants will be provided with personalized VIZO glasses. |
ZOHAR ELYOSEPH; | 2022-04-01 |
| 203 | A Pilot Study to Assess The Efficacy and Safety of A Novel Device (VIZO Glasses) in The Management of ADHD in Adolescents PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a 2-month study in which eligible ADHD adolescents will be provided with personalized VIZO Glasses |
ZOHAR ELYOSEPH; | 2022-04-01 |
| 204 | Can Fidgeting Lead to Enhanced Attention and Emotional Regulation in ADHD? PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This project will study how fidgeting relates to cognitive and emotional functioning in adults with attention-deficit/hyperactivity disorder (ADHD). It will determine, in a laboratory setting, whether movement and access to a fidget device providing sensory and motor stimulation can improve cognitive and emotional regulation (including on physiological measures) in adult ADHD. The investigators will also acquire pilot data for machine learning analyses to be used in future, … |
JULIE SCHWEITZER; | 2022-03-21 |
| 205 | Double-blind Randomized Placebo-controlled Trial of The Efficacy of The Apollo System for Children With ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: To determine the extent to which the Apollo System is effective in reducing symptomatology associated with ADHD. |
MATTHEW B. PONTIFEX; | 2022-03-18 |
| 206 | A Phase II Proof-of-concept Trial of Methylphenidate in Children With Apraxia of Speech: A Double-blind, Randomised, Placebo-controlled, Cross-over Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to describe the possible effects of methylphenidate (MPH) on speech intelligibility in children with childhood apraxia of speech (CAS) aged 6-12 years. This outcome will be compared between MPH intake and placebo intake. |
ANGELA MORGAN; | 2022-03-14 |
| 207 | Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for Attention Deficit Hyper Activity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this pilot study is to determine the effects of 15 minutes of sensory-play based (SenPlay) intervention on improving focused attention in developmentally appropriate tasks in young children with or at risk for ADHD. |
THUBI KOLOBE; | 2022-03-09 |
| 208 | Clinical Study of Comorbidities of Attention Deficit Hyperactivity in Children and Adolescents PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Determine the frequency of psychiatric and neurological comorbidities in children and adolescence diagnosed with ADHD. |
SALMA MOHMED; | 2022-03-01 |
| 209 | Determinants of Treatment Response to State-of-the-art Interventions for Attention Deficits: Child Temperament, Cognitive Profiles and Family Dynamics PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The main aim of this study is the development and implementation of a multimodal intervention program consisting of parent training and child training which utilizes the potentials of immersive virtual reality technology (iVR) in order to test its effectiveness for children with attention deficits. |
PANAGIOTA DIMITROPOULOU; | 2022-03-01 |
| 210 | A Virtual Clinic for Parents of Children With ADHD – An Individually-tailored Approach to Reduce Parental Distress PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aims of the present study is to investigate the efficacy of a co-designed individually-tailored Internet intervention for parents of children with ADHD. |
COSTINA-RUXANDRA PĂSĂRELU; | 2022-03-01 |
| 211 | The Effects of A Peer Co-led Educational Programme for Parents of Children With ADHD: A Feasibility Randomized Controlled Trial Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD is associated with a substantial burden on families, and systems pertaining to health, social care, and criminal justice, and there is a need for more knowledge of the effects of non-pharmacological interventions. Educational and parental activation interventions may improve ADHD symptoms, and may enhance parent activation. Although the results of these studies are promising, few interventions have been carried out in collaboration with user representatives, which is required by Norwegian legislation. As such, there is a need for clinical studies that document the effects of educational group interventions based on user involvement that seeks to improve parental activation. Furthermore, … |
INGUNN P. MUNDAL; | 2022-03-01 |
| 212 | A Phase 3, Multicenter, Open-label, Long-term Trial Evaluating The Long-term Safety and Tolerability of Once Daily Centanafadine Capsules in Children and Adolescents With Attention-deficit/Hyperactivity Disorder (ADHD) PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary purpose of this trial is to evaluate the safety and tolerability of centanafadine QD XR in pediatric subjects with ADHD. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2022-02-24 |
| 213 | A Randomized Controlled Trial of Digital Cognitive Behavioral Therapy for Insomnia (dCBTi) for Adults With Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The current study aims to evaluate the efficacy and feasibility of a digital application-based CBTi treatment devised for adults with ADHD and insomnia compared to self-monitoring and sleep hygiene control condition. |
CHAN WAI SZE; | 2022-02-21 |
| 214 | Supporting The Implementation of A State Policy on Screening for Adverse Childhood Experiences (ACEs) in Federally Qualified Health Centers (FQHC) PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: Adverse Childhood Experiences (ACEs) are pervasive among children with 45% experiencing at least one ACE and 10% experiencing three or more, placing them at high risk for toxic stress and symptomatology. Yet, ACEs often go undetected in primary care settings during well-child visits due to unclear policies and tested implementation strategies. This pilot study will use mapping methodology, guided by the EPIS framework, to refine a multi-faceted strategy supporting the implementation of the state of California’s 2020 policy promoting universal ACE screening in community clinics, … |
MONICA PEREZ JOLLES; | 2022-02-18 |
| 215 | Hyperactivity Assessment in Children With Attention-deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. Clinical diagnosis of this disorder depends of history taking, parent report, and questionnaire. Attention test such as continuous performance test can provide quantitative measurement on attention deficits; however, … |
NATIONAL TAIWAN UNIVERSITY HOSPITAL | 2022-02-16 |
| 216 | Evaluation of An Explicit Approach to Teach Grammatical Forms to Children With Language Impairment PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a randomized clinical trial that uses a Sequential Multiple Assignment Randomized Trial (SMART) study design. The study will directly compare the efficacy of an innovative intervention that combines explicit and implicit approaches to a traditional implicit treatment approach to teach true grammatical forms to children with developmental language disorder (DLD). The study will also compare interventions that include sequences of Explicit-added and Implicit-only treatments. Participants will include 5- through 9-year-old children with DLD who present with significant grammatical weaknesses. In Phase 1, … |
UNIVERSITY OF MINNESOTA | 2022-02-15 |
| 217 | Attention Management Trial for Children With FASD – A N-of-1 Control Trial of Prescribed Stimulants for ADHD in FASD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a double-blind, placebo controlled, series of N-of-1 trials of individualised stimulant dose on ADHD symptomatology in children with FASD. The broad aim of this study is to contribute new evidence towards understanding treatment efficacy for ADHD symptoms in FASD. Specific aims are: 1. To assess the ongoing effectiveness of stimulant medication prescribed for ADHD symptoms in individual children with FASD of clinically prescribed stimulant medication compared to placebo to control ADHD symptoms (using behavioural and cognitive measures) in children with FASD and ADHD using a N-of-1 trial design. 2. To obtain pilot data to examine feasibility and tolerability of the planned N-of-1 trial design in children with FASD and ADHD for future and larger studies that might seek to examine if the different stimulant types are equally effective relative to placebo. 3. To review the multiple N-of-1 data to analyze key individual factors that mediate the effect of stimulants relative to placebo on ADHD symptoms, including underlying child factors (attention skills, cognitive function), sociodemographic factors and other prenatal exposures. |
ALISON CRICHTON; | 2022-02-14 |
| 218 | THRIVE-ASD: Telehealth Rapid Intervention for Externalizing Behaviors in ASD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this research study is to evaluate a time-limited version of Parent Child Interaction Therapy (PCIT) delivered via telehealth for young children with autism spectrum disorder (ASD) and disruptive behavior problems. Families will be randomly assigned to receive 10 sessions of Tele-PCIT or Treatment as Usual. Families will complete a baseline assessment, a post-treatment assessment, and a 3-month follow-up. |
ROSMARY ROS-DEMARIZE; | 2022-02-11 |
| 219 | A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Determine The Efficacy and Safety of Once Daily Centanafadine Capsules for The Treatment of Adolescents With Attention-deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This trial will be conducted to evaluate the efficacy and safety of the Centanafadine extended release (XR) capsules in adolescent subjects (13 – 17 years, inclusive) with ADHD. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2022-02-02 |
| 220 | Combined PET and MR Investigations of The Pathophysiology of Gilles De La Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Gilles de la Tourette syndrome (GTS; also known as Tourette syndrome) is a congenital neuropsychiatric disorder. Characteristic symptoms are so-called tics-rapid, repetitive movements (motor tics) or vocalizations (vocal tics) that start suddenly without any apparent purpose. Previous research supports the hypothesis of defective regulation (dysregulation) of the dopaminergic system, with particular discussion of dysfunction of tonic/phasic dopamine release or dopaminergic hyperinnervation. Moreover, given the complex interaction of different neurotransmitters, especially in the basal ganglia, it can be assumed that abnormal dopaminergic transmission also affects other transmitter systems, such as glutamate (Glu) or γ-aminobutyrate (GABA). Furthermore, … |
HARALD E MÖLLER; | 2022-02-01 |
| 221 | An Effectiveness Trial Examining Neurofeedback in Adults With PTSD Related Papers Related Patents Related Grants Related Experts View Highlight: This study is an effectiveness trial investigating neurofeedback (NFB) in adults with PTSD (Post-Traumatic Stress Disorder). Participants will be randomly assigned to one of two treatment conditions – i) NFB, or ii) wait list. Due to the coronavirus pandemic, our study will, primarily, take place online (i.e., online assessment and treatment, with option of in-person fMRI, or functional magnetic resonance imaging, scans). NFB sessions will be conducted from home, with videoconferenced supervision by research staff. After study completion, individuals in the wait list condition will be offered the same NFB treatment. |
RUTH LANIUS; | 2022-02-01 |
| 222 | Comparative Evaluation of Plaque Removal Efficacy of Electric Toothbrushes Between Children With Attention Deficit And Hyperactivity Disorder And Healthy Children PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: A total of 52 children, 26 of whom were diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) as the experimental group and 26 healthy with no systemic disease as the control group, were included in the study. Then, in order to evaluate the effectiveness of electric and manual toothbrushes, each group was randomly divided into 2 subgroups: Electric and Manual. Children were educated on toothbrushing according to subgroups. DMFT/dft and Löe-Silness Gingival Index (GI) values were recorded. At the first appointment, … |
MELIS AKYILDIZ; | 2022-01-29 |
| 223 | Combined PET and MR Investigations of The Pathophysiology of Gilles De La Tourette Syndrome. Part 2: 7T MRI PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Gilles de la Tourette syndrome (GTS; also known as Tourette syndrome) is a congenital neuropsychiatric disorder. Characteristic symptoms are so-called tics-rapid, repetitive movements (motor tics) or vocalizations (vocal tics) that start suddenly without any apparent purpose. Previous research supports the hypothesis of defective regulation (dysregulation) of the dopaminergic system, with particular discussion of dysfunction of tonic/phasic dopamine release or dopaminergic hyperinnervation. Moreover, given the complex interaction of different neurotransmitters, especially in the basal ganglia, it can be assumed that abnormal dopaminergic transmission also affects other transmitter systems, such as glutamate (Glu) or γ-aminobutyrate (GABA). Furthermore, … |
HARALD E MÖLLER; | 2022-01-27 |
| 224 | A Randomised Controlled Trial of The Effects of A Probiotic Drink on Behaviour, Sleep and The Microbiome in Children With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This randomised, placebo controlled trial explores the effects of supplementation with a probiotic drink (kefir) in children diagnosed with ADHD on behaviour, sleep, attention and the gut microbiome. |
KATE LAWRENCE; | 2022-01-06 |
| 225 | Treatment Efficacy of Multiple Family Narrative Therapy for Chinese Families of Children With Dyslexia: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this randomized controlled trial (RCT) is to develop and to implement a multiple family narrative therapy (MFNT) intervention consisting of parent-child relationships training among Chinese families of children with Dyslexia (CFCDs). The intervention aims to reduce the psychological distress of parents and their child, thus improving parent-child relationships, and the trial aims to assess the effectiveness of MFNT among them. A RCT design supplemented by qualitative interviews will be used to evaluate the effectiveness of MFNT on family welfare. |
TAK MAU CHAN; | 2022-01-01 |
| 226 | Randomized Controlled Trial of The Myndlift BPT App PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: We propose addressing these aims by conducting a randomized controlled trial (RCT) that will evaluate the hybrid BPT (Myndlift BPT) compared to a wait-list control group. All participants will receive the Myndlift BPT at either the initial point of randomization or following the wait-list time period. The Myndlift BPT consists of 10, … |
ANIL CHACKO; | 2022-01-01 |
| 227 | Evaluation for The Pilot Scheme on New Service Protocol for Attention Deficit/Hyperactivity Disorder With Comorbidity (ADHD+): A Randomized Waitlist-controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The proposed study is to be carried out in 2021 – 2024 with youths aged 6 – 15 in Hong Kong. This is a randomized waitlist-controlled trial that aims to examine the effectiveness of the ADHD+ new service protocol. This ADHD+ new service protocol intervention will be delivered for 6 months in the format of groups by frontline social workers trained by professional clinicians including clinical psychologists and psychiatrists. It is designed to reduce ADHD and related symptoms in individuals aged between 6 and 15 years. Core treatment components include internet use/addiction intervention, cognitive training, emotion management, social skills training, … |
YI-NAM SUEN; | 2021-12-20 |
| 228 | Impact of Early Craniosacral Evaluation and Treatment on The Optimization of Infant Neurodevelopment PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Craniosacral exploration and therapy is one of the innovative palpation and treatment techniques in specialized physiotherapy, which can contribute in an efficient, subtle and sudden way to the detection of dysfunctions in the cranial sutures or fontanelles and/or alterations or blockages that may exist in the frontal lobes and other areas of the skull and body. Objective: To demonstrate the need for programs that consider preventive evaluation and specialized physiotherapeutic treatment (craniosacral therapy) in schools and health centers during all stages of child growth (from birth to 12 years of age), maximizing the development of the child’s physical, emotional, psychosocial, … |
GEMA LEÓN BRAVO; | 2021-12-18 |
| 229 | Safety and Efficacy of Repeated Low Dose D-Lysergic Acid Diethylamide (LSD) D-tartrate (MM-120) As Treatment for ADHD in Adults: A Multi-center, Randomized, Double-blind, Placebo-controlled Phase 2a Proof of Concept Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study measures the safety and efficacy of repeated low dose MM-120 as treatment for ADHD in adults: a multi-center, randomized, double-blind, placebo-controlled |
KIM KUYPERS; | 2021-12-17 |
| 230 | Moderators and Mediators of Behavioural Parent Training Outcomes for Children With Attention-deficit/Hyperactivity Disorder: Evaluating The Importance of Addressing Parent Psychopathology and Treatment Process Factors PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Behavioural parent training (BPT) is a front-line treatment for children with attention-deficit/hyperactivity disorder (ADHD) that teaches parents how to support their child and manage behaviour. Parents of children with ADHD who have their own elevated ADHD/depressive symptoms may be less likely connect/engage and benefit from BPT. The current study modifies a BPT program that specifically addresses peer difficulties as these are common in children with ADHD. The goal of the modifications is to enhance the treatment process (how much parents connect and engage with the treatment) for parents with elevated ADHD/depressive symptoms. The Investigators will test whether this intervention increases parent engagement/connection to the program and whether it improves parenting behaviour. |
AMORI YEE MIKAMI; | 2021-12-10 |
| 231 | Descriptive and Risk Factor Analysis of Neuropsychiatric and Neurodevelopmental Disorders in Children With Systemic Inflammatory Disease PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: Systemic inflammatory diseases in children include autoinflammatory diseases (deregulation of the innate immune system with production of pro-inflammatory cytokines) and autoimmune diseases (deregulation of the adaptive immune system with production of pathogenic autoantibodies). Neurological damage has been reported in both cases, but the neurodevelopmental psychiatric manifestations are poorly known, especially in children. Neurodevelopmental disorders are a broad spectrum of pathologies that are underpinned by common symptomatic dimensions. They have a common physiopathology combining genetic predisposing factors as well as environmental risk factors, making it possible to study them from a global point of view. Among the environmental risk factors, … |
ISABELLE MELKI; | 2021-12-06 |
| 232 | Healthcare Resources Utilization and Associated Costs of Adult ADHD in England PF:6 Related Papers Related Patents Related Grants Related Experts View Highlight: The main aim of the study is to learn about the demographic and clinical characteristics, healthcare resources utilization (HCRU) and costs associated with before and after ADHD diagnosis in England. No study medicines will be provided to participants in this study. The record available in Clinical Practice Research Datalink (CPRD) database and Hospital Episode Statistics (HES) database for ADHD participants will be assessed. |
TAKEDA | 2021-12-01 |
| 233 | An Open-label, Flexible Dose, Single Site Study Evaluating The Safety, Efficacy and Tolerability of Cariprazine As An Adjunct to Psychostimulants in Adult Patients With ADHD Who Have Had An Inadequate Response to Psychostimulants Alone PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: According to the Canadian ADHD Practice Guidelines, psychostimulants are the preferred treatment of attention-deficit/hyperactivity disorder (ADHD), especially for those that require urgent care. Specifically, long-acting psychostimulants are considered the gold-standard pharmacological treatment for ADHD. Using extended-release formulations, long-acting psychostimulants provide an extended duration of daily symptom relief in addition to overall reductions in ADHD symptoms that are maintained over time. In accordance with these guidelines, clinicians may combine psychostimulants with other medications when it is considered necessary. For complex cases, … |
MARTIN A. KATZMAN; | 2021-12-01 |
| 234 | The Effects of Functional Power Training on Attention, Gross and Fine Motor Skills, Participation and Quality of Life in Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is aimed to investigate the effectiveness of functional power training on attention, gross and fine motor skill, participation and quality of life in children with attention deficit hyperactivity disorder (ADHD) by comparing traditional strength training and their healthy peers. In the literature, there are limited studies that investigate the effect of power exercise in children with ADHD. But there is no randomized controlled trial include power exercises which is designed to the National Strength and Conditioning Association (NSCA) criteria and investigate the effects on attention, gross and fine motor skill, … |
OZGUN KAYA KARA; | 2021-12-01 |
| 235 | A Single Arm, Adaptive Design, Pivotal Trial to Assess The Efficacy of AKL-T01, A Novel Digital Intervention Designed to Improve Attention, in Adults Diagnosed With Attention Deficit Hyperactive Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effects of the videogame-like digital therapy on attentional functioning and symptoms in Adults diagnosed with ADHD. |
AKILI INTERACTIVE LABS | 2021-11-29 |
| 236 | Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: In a prior application (MH064372), the investigators’ treatment research program (Services for Kids In Primary-care, SKIP) developed and tested a chronic care model-based intervention, called Doctor Office Collaborative Care (DOCC), that was found to be effective in the management of childhood behavior problems and comorbid ADHD. In the SKIP for PA Study, the investigators propose to conduct a randomized clinical trial to evaluate the effects of team- and practice leadership-level implementation strategies designed to enhance the use and uptake of DOCC in diverse pediatric primary care offices. |
DAVID KOLKO; | 2021-11-28 |
| 237 | Community-Based Care for Minority Adolescents With ADHD: Improving Fidelity With Machine Learning-Assisted Supervision and Fidelity Feedback PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This project proposes to reduce disparities in care among disadvantaged racial/ethnic minority adolescents with ADHD by improving community therapist fidelity to evidence-based behavior therapy through a technology-assisted supervision intervention. In Y01, the research team will work with stakeholders to develop the proposed supervision intervention utilizing two novel technologies: Lyssn + Care4 (LC4S). In Y02, a preliminary clinical trial (N=72) will be conducted in three community mental health agencies in Miami, … |
MARGARET SIBLEY; | 2021-11-18 |
| 238 | Comparative Effect of Rhythmic Balance Auditory Vision Training (Bal-A-Vis-X) and Aerobic Training in Children With Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: the aim of this study is to compare the effects of Rhythmic Balance, Auditory, and Vision Exercises and Aerobic training in children with Autism Spectrum Disorder. |
ARUBA SAEED; | 2021-11-11 |
| 239 | Prospective Study of Surgical Treatment of Children With Obstructive Sleep Apnea and Small Tonsils or Down Syndrome PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to prospectively compare the effectiveness of a novel personalized approach to the surgical treatment of obstructive sleep apnea (OSA) in children, drug induced sleep endoscopy (DISE) directed surgery versus the standard adenotonsillectomy (AT). This will also serve to test the feasibility of recruiting families for a future randomized protocol comparing the same surgical techniques. It is the investigators’ central hypothesis that a personalized DISE-directed surgical approach that uses existing procedures to address the specific fixed and dynamic anatomic features causing obstruction (ie, … |
DEREK LAM; | 2021-11-09 |
| 240 | Improving Health in People With Multimorbidity: A Paradigm Shift in Health Care From Disease-based Curative Models to Personalized Exercise Therapy and Self-management PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Chronic conditions such as knee or hip osteoarthritis (OA), chronic obstructive pulmonary disease (COPD), heart failure (HF), coronary heart disease (CHD), hypertension, type 2 diabetes mellitus (T2DM) and depression are among the leading causes of global disability and affect hundreds of millions of people around the world. In recent years, multimorbidity, commonly defined as the co-occurrence of at least two chronic conditions, has also gained interest due to its substantial impact on the person and society. Despite the significant burden of multimorbidity, … |
SØREN T SKOU; | 2021-11-01 |
| 241 | The Assessment of Transcendental Meditation Training on ADD/ADHD Symptoms of Adolescents Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common developmental disorders experienced in childhood, with limited options for effective pharmacological treatment. Transcendental Meditation (TM) has been proposed to be used as a tool for attentional training and modulating autonomic nervous system activity in the ADHD population. However, the empirical support in favor of meditation for ADHD is limited, … |
SHEBA MEDICAL CENTER | 2021-11-01 |
| 242 | Evaluation of The Effectiveness of The Therapeutic Education Program Living Better With ADHD in Improving The Quality of Life of Children With ADHD and Their Parents PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by attention deficit, impulsivity and hyperactivity. It’s one of the most frequently encoutered disorder in child psychiatry. ADHD has a significant impact on the quality of life of children and their parents. In the child psychiatry department of the MPEA Peyre Plantade, … |
UNIVERSITY HOSPITAL MONTPELLIER | 2021-10-01 |
| 243 | Assessing Cognitive Performance Among Adults With Attention Disorders Working on Treadmill PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Randomized clinical trial in which individuals who have been diagnosed with ADHD and are regularly treated with Methylphenidate will be test for cognitive performance and will be randomly examined in the following four conditions: – While taking Methylphenidate and sitting at a desk – While taking Methylphenidate and walking on a treadmill workstation – Without taking Methylphenidate while sitting at a desk – Without taking Methylphenidate while walking on a treadmill workstation The investigators will compare the cognitive achievements outcomes and evaluate the efficiency of studying in each of these four conditions. |
LIAT KORN; | 2021-10-01 |
| 244 | A Trial of Two-Week Brain Stimulation for Teenagers With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The objective of this clinical trial is to examine whether non-invasive brain stimulation can modulate dysfunctional brain dynamics underlying adolescent ADHD to subsequently improve clinical symptoms. |
BRADLEY HOSPITAL | 2021-10-01 |
| 245 | The Effect of Playing Dough on Children’s Adaptation to Nebulizer Treatment Children 3-6 Years Old Child Service: Randomized Controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to present the results of the effect of playing with play dough on treatment compliance in children aged 3-6 years receiving nebulizer therapy. In the randomized controlled study, … |
BEHICE EKICI; | 2021-10-01 |
| 246 | A Randomized Controlled Study of Medical-education-community Collaborated Intervention in Children With Attention Deficit Hyperactivity Disorder Related Papers Related Patents Related Grants Related Experts View Highlight: This study is designed to test if the medical-education-community collaborated intervention can reduce the symptoms of children with Attention deficit hyperactivity disorder (ADHD) compared to routine clinical care. Investigators will also evaluate if the intervention will positively affect organizational skills and academic achievement compared to controls. |
CHILDREN’S HOSPITAL OF FUDAN UNIVERSITY | 2021-10-01 |
| 247 | Clinical Observational and Statistical Study for Detection of Prevalence and Risk Factors of Disruptive Behavior in Children With Attention Deficit Hyperactivity Disorder (ADHD) Related Papers Related Patents Related Grants Related Experts View Highlight: Identification of prevalence and Risk factors for disruptive behavior in children with Attention Deficit Hyperactivity Disorder and Early recognition of disruptive behavior in children with ADHD |
EMAN SAYED HASSAN MAHROS; | 2021-10-01 |
| 248 | Longitudinal Impact of Stressors in Adults With Tourette Syndrome PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The Investigators propose a two-year, longitudinal pilot study of TS adults (\>18) to determine impact of lifetime environmental stress exposure on tic severity, psychiatric comorbidity severity, and health-related quality of life (HRQOL). |
DAVID ISAACS; | 2021-09-30 |
| 249 | Development of A Game-supported Intervention to Improve Learning and Study Strategies Among At-Risk Students PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators will develop and pilot test an innovative computer-assisted behavior intervention (CABI) for middle school students with attention-deficit/hyperactivity disorder (ADHD). The CABI will deliver evidence-based behavior interventions for ADHD in a manner that is acceptable to teachers and motivating for students. The key element of the CABI is a serious game that will teach and encourage rehearsal of ADHD coping skills in an engaging game environment. Transfer of those skills to authentic education settings will be facilitated by teacher interventionists in consultation with school or clinical psychologists. The investigators will test the CABI condition (n = 18) against traditional teacher consultation for ADHD (n = 18) on measures of consultation fidelity and student academic and behavioral outcomes. |
BRANDON SCHULTZ; | 2021-09-27 |
| 250 | Animal Assisted Intervention With Dogs for Children With Attention Deficit/Hyperactivity Disorder; Exploring Candidate Physiological Markers of Response to AAI PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This pilot study aims to replicate results of a previously studied novel, non-pharmacological psychosocial intervention for children with ADHD, utilizing an Animal Assisted Intervention with therapy dogs combined with traditional social skills training (AAI) compared to psychosocial treatment as usual with social skills training alone (TAU). This study also aims to determine if candidate physiological markers of HPA axis and ANS activity differ between groups and if these markers moderate response to the interventions. |
SABRINA E. BRIERLEY SCHUCK; | 2021-09-17 |
| 251 | Strengthening Social, Emotional and Behavioral Resilience: The RENEW (Resilience in Emotional and Behavioral Wellbeing) Pilot Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Behavioral and emotional disorders adversely affect overall health and well-being. Prevalence rates among children and adolescents classified with behavioral and emotional disorders or neurodevelopmental disorders (NDD), as recently redefined in ICD-11, have steadily increased over the past decade. In particular, prevalence rates among persons classified with Autism Spectrum Disorders (ASD), the fastest rising behavioral and emotional disorder, have sharply risen over the past five years and is now estimated at 1 in 54. Shared symptoms within behavioral and emotional disorders include persistent social, emotional and behavioral functioning deficits that often impact self-management, social-awareness and metacognition competences, … |
USMAN IQBAL; | 2021-09-07 |
| 252 | Could A Strength- Based Treatment Improve Self-management in Adults With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of the research is to develop a treatment program with positive self-awareness and self-determination outcomes for adults with Attention Deficit Hyperactivity Disorder (ADHD). Current treatments are based in a characterisation of ADHD oriented on deficits impairing everyday functioning, with primary goals of symptom control and reduction. However, treatment approaches are not standardised and only evidence short-term effectiveness. This project proposes an alternative approach to understanding ADHD behaviours, … |
REBECCA CHAMP; | 2021-09-06 |
| 253 | Training Workshops for Parents of Children With Attention Deficit Hyperactivity Disorder: Effects on The Child’s Agitation. Preliminary Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The therapeutic care of Attention Deficit Hyperactivity Disorder (ADHD) children focuses on the child but also on his environment and in particular his family. This type of approach has long existed in Anglo-Saxon countries. This project aims to collect preliminary data to build study to valid efficacy of a parenting skills program for parents of ADHD children in France and on the child’s hyperactivity. |
YVES CHAIX; | 2021-09-04 |
| 254 | A Short-term Exploratory Study to Evaluate Safety, Tolerability and Pharmacokinetics of Seltorexant As Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have An Inadequate Response to SSRI Monotherapy and Psychotherapy PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to assess the safety and tolerability of Seltorexant as adjunctive therapy to an antidepressant in adolescents with major depressive disorder (MDD) in the short-term compared with placebo. |
JANSSEN RESEARCH & DEVELOPMENT | 2021-09-02 |
| 255 | Dikkat Eksikliği Ve Hiperaktivite Bozukluğu Olan Çocukların Primer Bakım Verenlerinde Telepsikiyatrik Ebeveyn Eğitimi Programının Etkilerinin İncelenmesi PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study was conducted to examine the effects of a telepsychiatric parent training program implemented for primary caregivers of children with Attention Deficit Hyperactivity Disorder (ADHD). The study employed a quasi-experimental pre-test, post-test, and re-test control group design. It was conducted from March to June 2022 via videoconferencing with primary caregivers of children aged 7-12 years diagnosed with ADHD, registered at the Child and Adolescent Mental Health Outpatient Clinic of Dokuz Eylül University Hospital. Caregivers in the experimental group completed Turkey’s first Telepsychiatric Parent Training program, … |
ZUMRA ULKER DORTTEPE; | 2021-09-01 |
| 256 | Adapting A Remote Training for Mexican School Clinicians Delivering Evidence-Based Intervention for ADHD and ODD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Neurodevelopmental disorders of inattention and disruptive behavior, such as Attention-Deficit/ Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder (ODD), are among the most common youth mental health conditions across cultures. An efficacious and feasible solution to improving affected youth’s ADHD/ODD is training existing school clinicians to deliver evidence-based intervention with fidelity. Despite initial promising results of training school clinicians to treat ADHD/ODD in settings suffering from high unmet need, such as Mexico, scalability is limited by a lack of researchers with capacity to train, monitor, and evaluate school clinicians in such efforts on a large scale. Thus, … |
LAUREN M HAACK; | 2021-09-01 |
| 257 | Examining The Effects of Parenting Interventions on Children With Attention-Deficit / Hyperactivity Disorder (AD/HD) and Their Parents PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study investigates the effects of parenting interventions on improving the emotion regulation and functioning of the children with AD/HD as well as their parents’ parenting practices and psychological well-being. Two kinds of parenting interventions are selected in this study, namely the Mindful Parenting and Tuning in to Kids programs. The value of this project lies in empowering parents through parenting techniques which they can use both for themselves and for their daily interactions with children. It is hoped to alleviate their stress from the role of parenting children with special needs, … |
IRIS KIT YEE LAM; | 2021-09-01 |
| 258 | An Open-lable Investigation of The Effect of RTMS on Attention in An Adult Sample Suffering From ADD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of the current open-lable study was to use low-frequency repetitive transcranial magnetic stimulation (rTMS) to improve the attention deficits in a sample of adult patients suffering from attention deficit disorder. Participants received 10 sessions of rTMS over Fz (located using the EEG 10-20 international system) and underwent assessments of their attentional capacity using the gradCPT task in an fMRI scanner, before and after the intervention. Other behavioral assessments of their attention symptoms have also been conducted. |
REZA KAZEMI; | 2021-09-01 |
| 259 | INFANT HEALTH- Supporting Infants’ Mental Health and Healthy Weight Development Through Community Health Nurses’ Promoting Sensitive Parenting PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Mental health problems and overweight often co-occur, they have their origin in early childhood and new research evidence suggest a key role of cognitive, emotional and behavioral regulation in the early developmental trajectories and points to the benefits of intervention in infancy that builds on strategies of sensitive parenting. The research group behind this project has developed the PUF program (PUF: In Danish: ‘Psykisk Udvikling og Funktion’) to target infants’ mental health and development within the settings of community health nurses. Still, … |
ANNE METTE SKOVGAARD; | 2021-08-16 |
| 260 | COMT Inhibition As A Potential Therapeutic Target Among Individuals With Comorbid Alcohol Use Disorder and Attention-Deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, affects response to alcohol, decision-making, brain activation associated with alcohol cue reactivity, response inhibition, and selective attention, or alcohol drinking. |
JOSEPH P SCHACHT; | 2021-08-16 |
| 261 | Effects of Acceptance and Commitment Therapy-based Asthma Management Training Program for Parents of Young Children With Neurodevelopmental Comorbidities: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This randomized controlled trial aims to examine the effectiveness of the Acceptance and Commitment Therapy-based Asthma Management Training Program on the health outcomes of asthmatic children with attention deficit hyperactivity disorder (ADHD) and their caregivers over a 12-month post-intervention. |
YUEN YU CHONG; | 2021-08-11 |
| 262 | Solriamfetol for ADHD in Adults: A Double-Blind Placebo Controlled Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: A double-blind, placebo controlled study of solriamfetol for adults age 18 to 65 with diagnosis of Attention Deficit Hyperactivity Disorder. |
CRAIG B. SURMAN; | 2021-08-06 |
| 263 | Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations occurring in the post-weight loss setting, including neuroendocrine-mediated changes in appetite/satiety and reduction of energy expenditure. Following weight loss, peripheral and central mechanisms respond in a way similar to starvation by conveying a sense that energy reserves have dwindled, activating a strong counter-response to increase caloric intake. Moreover, metabolic rate drops, further compounding the propensity for weight rebound. Adolescents with severe obesity are not immune to the vexing issue of weight regain; therefore, … |
AARON KELLY; | 2021-08-04 |
| 264 | Targeting Self-Regulation in Family-Based Behavioral Treatment for Obesity and Cardiovascular Disease Prevention PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The main purpose of vHAPPY is to pilot test a new type of virtual family-based healthy lifestyle program for children aged 8-14 with obesity and their caregivers. vHAPPY aims to (1) Transition a previously developed acceptance-based behavioral treatment to web-based platform, utilizing qualitative and quantitative program evaluation data from past participants. (2) Determine the feasibility, acceptability, and preliminary outcomes of the adapted web-based treatment. (3) Evaluate whether the adapted web-based treatment (self-guided treatment + brief coaching) is similar to the traditional treatment (interventionist-guided treatment) in terms of feasibility, acceptability, and preliminary outcomes utilizing a non-randomized sequential arm design. |
MARISSA GOWEY; | 2021-08-01 |
| 265 | A Phase IV, Open-Label, Flexible-Dose Safety Trial Evaluating SPN-812 Administered With Psychostimulants in Children and Adolescents (6 to 17 Years of Age) With Attention-Deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This open label, flexible-dose study evaluating the safety and efficacy of SPN-812 administered with psychostimulants in children and adolescents (6 to 17 years of age) with Attention-Deficit/Hyperactivity Disorder (ADHD). |
SUPERNUS PHARMACEUTICALS | 2021-07-27 |
| 266 | Feasibility Open Label Study Evaluating The Use of Process-instructed Self Neuro-Modulation (PRISM) for Attention Deficit/ Hyperactivity Disorder – Adults PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a single-arm, open-label feasibility study. A maximum of 30 participants will be enrolled. 15 participants will be assigned and will undergo a novel neurofeedback intervention, targeting down-regulation of deep limbic structures, specifically the amygdalae. Participants will complete 12 neurofeedback sessions delivered twice weekly over 6 consecutive weeks. The intervention will be delivered via the PRISM platform. |
LENARD ADLER; | 2021-07-26 |
| 267 | Adaptation and Implementation of An ASD Executive Functioning Intervention in Children’s Mental Health Services PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this project is to conduct a feasibility test of an ASD executive functioning intervention adapted for mental health settings, including examining the effectiveness and process of implementing this adapted intervention in community mental health programs. |
KELSEY DICKSON; | 2021-07-15 |
| 268 | The ACTyourCHANGE Study Protocol: An ACT Based Inter-vention for Adolescents With Obesity: A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This Randomized Controlled Trial (RCT) aims to evaluate the effectiveness of a brief Acceptance and Commitment Therapy (ACT)-based-intervention combined with treatment as usual (TAU) compared to TAU only in improving psychological conditions in a sample of adolescents with obesity (body mass index, … |
GIANLUCA CASTELNUOVO; | 2021-07-01 |
| 269 | Effect of Nutritional Formula Supplementation on Growth of Prepubertal Children Treated With Stimulants Medications for ADHD. A Randomized Double-blind, Placebo-controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The proposed study is a double blind, randomized, placebo controlled study. The aim of the study is to evaluate the effect of nutritional formula supplementation on growth of prepubertal children treated with stimulants medications of ADHD. 70 Participants treated with stimulants medications of ADHD will be randomly assigned either to the intervention group or the placebo control group. Randomization for the two study groups will be made in a ratio of 1:1. Both participants and study team will be blinded to the type of treatment that each patient will receive during the study. Randomization will be stratified according to gender. Participants in the intervention groups will be treated with the study formula and participants in the control group will be treated with a placebo low caloric formula (Powder added to water). The study will continue for 6 months of intervention versus active placebo, with additional 6 months (an extension period), in which participants at both groups, the intervention and the placebo, will be offered to continue their participation in the study with the active study supplement. In addition, 30 prepubertal healthy siblings will be recruited to the study in order to compare baseline eating and physical activity patterns of ADHD children treated with stimulants to their healthy untreated siblings at the same age range. Participants’ siblings will only complete once the nutritional and physical activity questionnaire and report height and weight measurements. |
MOSHE PHILLIP; | 2021-07-01 |
| 270 | Cognitive-Behavioral Therapy for Adults With Attention-Deficit/Hyperactivity Disorder Inattentive Presentation: A Qualitative Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a qualitative study of participants who have taken part in a randomized controlled trial (RCT) of a new treatment protocol based on cognitive-behavioral therapy for adults with attention deficit/hyperactivity disorder predominantly inattentive presentation. The purpose of the qualitative study is to explore participant perceptions of taking part in the RCT to further develop and improve the new treatment protocol. |
BENJAMIN BOHMAN; | 2021-07-01 |
| 271 | A Single Arm Pivotal Trial to Assess The Efficacy of AKL-T01, A Novel Digital Intervention Designed to Improve Attention, in Adolescents, Aged 13-17 Years Old, Diagnosed With Attention Deficit Hyperactive Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effects of videogame-like digital therapy on attentional functioning and symptoms in adolescents ages 13-17 diagnosed with ADHD |
AKILI INTERACTIVE LABS | 2021-06-29 |
| 272 | Care Improving Cognition for ADolescents on The Autism Spectrum (CICADAS) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a validation study to evaluate the acceptability, feasibility and impact of CICADAS (Care Improving Cognition for ADolescents on the Autism Spectrum), a clinician-assisted, digital application that aims to prime the brain to engage in flexible, adaptive long-term learning about social-emotional events through closed-loop technology. |
KYU LEE; | 2021-06-11 |
| 273 | Prevalence of Attention Deficit/Hyperactivity Disorder and Parenting Stress in School-age Children in Chongqing, China PF:7 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder. Around 7.2% of children around the world are suffering from ADHD, while a chinese meta-analysis shows that the prevalence is 6.28%. There is no study of ADHD prevalence have used population-based samples, and depending on Vanderbilt ADHD Diagnostic Parent Rating Scale (VADPRS), in Chongqing, China. The purpose of the study is to investigate the prevalence of ADHD in school-age children and the parenting stress of parents of ADHD children in Chongqing. According to the proportion of primary school students in the four regions of Chongqing, … |
CHEN LI; | 2021-06-01 |
| 274 | The Relationship Between Motor Development Between 1-18 Months and The Risk of Developmental Coordination Disorder (DCD) in The Preschool Period and Cerebral Palsy (CP) in Risky Infants PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary purpose of this study is to evaluate the relationship between the developmental level between 1-18 months and gross motor performance in the preschool period in risky infants followed up from a center for early intervention, and to determine the risk of developmental coordination disorder in the preschool period in risky infants.Gross Motor Function Measurement-88 will be applied to children diagnosed with cerebral palsy in the pre-school period to evaluate motor performance, … |
OZGE KARANLIK; | 2021-06-01 |
| 275 | Inter-Brain Synchrony in Psychotherapy for Test Anxiety Related Papers Related Patents Related Grants Related Experts View Highlight: The study aims to examine inter-brain synchrony between patients and therapists over the course of psychotherapy. Eight patients underwent a 6-session course of psychotherapy for test anxiety including Cognitive Behavioral Therapy (CBT) and imagery work, following an existing protocol (see Prinz et al., 2019), as well as a pre- and post- treatment interview (with different interviewers). The researchers used functional near-infrared spectroscopy (fNIRS) imaging to record brain activity during both interviews and sessions 1, 3, and 5, and collected saliva samples to measure hormone levels during the same sessions. Participants completed questionnaires before and after the study, … |
UNIVERSITY OF HAIFA | 2021-05-23 |
| 276 | Evaluation of The Effectiveness of The FOCUS ADHD Mobile Health Platform in The Monitoring of Adults With Attention-Deficit/ Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study is a randomized clinical trial to evaluate the efficacy on treatment adherence, performance and usability of the mobile health solution FOCUS ADHD, in combination with a discount application in the purchase of psychostimulant medication by adult patients with ADHD |
LUIS AUGUSTO P ROHDE; | 2021-05-21 |
| 277 | Microbial Stool Biomarkers for Prediction of Autism and ADHD in Children PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Autism (ASD) is one of the frequent neurodevelopmental disorders that children would occur. Many studies have shown that individuals with Autism are more common to experience significant gastrointestinal problems than other individuals. Symptoms include constipation, diarrhea, abdominal pain and gastric reflux. A recent study with 50 children with ASD, 50 children with other developmental disabilities and 50 healthy control children, it found that 70% of ASD children had presented with GI symptoms, compared with 42% of developmental disabilities children and 28% of developing children, … |
SIEW CHIEN NG; | 2021-05-15 |
| 278 | Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children, and Modulation of Brain Activity By Transcutaneous Electrical Nerve Stimulation – A Functional Magnetic Resonance Imaging Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the aim is to investigate if sacral transcutaneous electric nerve stimulation (TENS) has a central mechanism of action. Children with OAB and DUI will be recruited from involved pediatric departments, and functional magnetic resonance imaging (fMRI) will be performed before and after 10 weeks of sacral TENS. In healthy children without bladder symptoms, … |
KRISTINA THORSTEINSSON; | 2021-05-05 |
| 279 | Maximizing TrEatment of Neurological Dysfunction Using INtravenous Guanfacine Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This proof-of-concept study examines whether the acute brain dysfunction that occurs in critically ill patients is improved by administration of intravenous guanfacine. |
CHRISTOPHER G HUGHES; | 2021-05-04 |
| 280 | An Internet-delivered Intervention for Coping With ADHD in Adulthood – A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary aim of this study is to examine the efficacy of a self-guided Internet-delivered intervention for coping with ADHD. The secondary aim is to investigate the effects of individual adaptation of the intervention on adherence, satisfaction and clinical outcomes. |
ROBIN MARIA FRANCISCA KENTER; | 2021-04-27 |
| 281 | Tracking The Efficiency of MyMind BrainHero® Personalised Neurofeedback in Patients With Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study investigates the feasibility and the effects of training at home with personalised neurofeedback in children with an autism spectrum diagnosis and comorbidities. The personalisation relies on quantitative electroencephalography recordings performed in a clinic, which are also used to evaluate the efficiency of the home-based training, along with standardized questionnaires. The active phase is expected to last roughly 6 months, during which children are expected to complete multiple hours of training and complete an interim evaluation. Whether the training’s effects are long lasting is evaluated in a follow-up phase, 3 months after the active phase. |
NEDJELJKA BALDASS; | 2021-04-14 |
| 282 | High Resolution Electroencephalography Exploration of Tactile Prediction Development PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This project aims to measure repetition suppression and tactile prediction using high-resolution electroencephalography in preschoolers, in order to describe the responses as a function of age, gestational age of birth and the presence of a neurodevelopmental disorder. We will include 100 children aged 2 or 6 years: 25 2-year-olds born prematurely, 25 2-year-olds born at term, 25 6-year-olds with typical development and 25 6-year-olds with neurodevelopmental disorders. We will perform several behavioral evaluations to analyze the results in view of the quality of development. |
UNIVERSITY HOSPITAL CAEN | 2021-04-01 |
| 283 | Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Investigators propose a cross-sectional, observational pilot study to examine the contribution of stress, family dynamics, and peer relationships to quality of life (QOL) in adolescents with Tourette syndrome (TS). Investigators will recruit two groups of participants: 1) adolescents aged 13-17 years of age with TS and 2) adolescents aged 13-17 without any neurologic or psychiatric diagnoses. Participants and one of their parents/caregivers will complete a series of questionnaires screening for and quantifying the extent of stress and mental health symptoms, including anxiety, depression, obsessive compulsive disorder (OCD), … |
DAVID ISAACS; | 2021-03-29 |
| 284 | Improving Symptom Trajectories of Tic Disorders and Co-occurring Diagnoses: The Role of Integrative Intensive Intervention PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose to the current study was to examine the efficacy of a telehealth, group-based, combined and intensive intervention for youth with tic disorders (TDs) and common co-occurring diagnoses. Families seeking treatment for TDs and common co-occurring diagnoses will be randomly assigned to receive treatment immediate (enrollment in the next group) or remain on a 1-month waitlist, and then receive treatment. Outcomes will be assessed across the treatment phase, immediately following treatment (post), as well as 1-month following the end of treatment. |
FLORIDA INTERNATIONAL UNIVERSITY | 2021-03-26 |
| 285 | Association Between Presence and Parental Participation in Perinatal Care and Child Psychiatric Profile at 24 Months After Preterm Birth Related Papers Related Patents Related Grants Related Experts View Highlight: The aims of the study is to evaluate the association between presence and parental participation in perinatal care and psychic development of the child at 24 months |
CHU DE REIMS | 2021-03-19 |
| 286 | Assessment of Brain Activity Associated With Inhibition of Action in Attention-deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Inhibitory control allows individuals to suppress unwanted actions and to resist irrelevant stimuli. It is thought to be a core deficit in Attention-deficit/hyperactivity disorder (ADHD). The present study aims at evaluating this deficit in adults with ADHD. Executive and inhibitory capacities, as well as the neural mechanisms underlying inhibitory control, will be assessed in adults with ADHD and two control groups of participants. |
JEREMIE PARIENTE; | 2021-03-17 |
| 287 | A Non-randomized Pilot Study on Brief Behavioral Parent Training for Behavioral Problems of Children With ADHD Symptoms PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This pilot study investigates a new, easily applicable, individually tailored first-line behavioral training for parents of children (4-12 years) with (symptoms of) ADHD, that will be provided in an early stage, before other treatments have been applied. In this pilot study the feasibility of the newly developed intervention will be evaluated by exploring program acceptability, including client satisfaction, recruitment, retention, treatment fidelity and therapist satisfaction. Also acceptability of potential outcome measures will be explored, including preliminary tests of efficacy. |
B. J. VAN DEN HOOFDAKKER; | 2021-03-16 |
| 288 | Effects of Subconcussive Head Impacts on Neural Integrity and Function in ADHD: A Case-control Intervention PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to examine the acute neural responses to subconcussive head impacts in individuals with Attention-deficit/hyperactivity disorder (ADHD). The study is designed to identify the effects of 10 controlled soccer headings in college-aged soccer players diagnosed with ADHD and without ADHD, through the use of neural-injury blood biomarkers, functional and diffusion MRI, and ocular-motor function across three acute timepoints. The central hypothesis is that neuronal structural, physiological, and functional impairments from subconcussive head impacts will be amplified by ADHD. The neural-injury blood biomarkers neurofilament light (NF-L), glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase-L1 (UCHL-1), … |
KEISUKE KAWATA; | 2021-03-15 |
| 289 | A Phase 1b, Multicenter, Open-label, Multiple Ascending Dose Trial to Assess The Pharmacokinetics, Safety, and Tolerability of Centanafadine Extended-release Capsules After Oral Administration in Pediatric Subjects (4 to 12 Years, Inclusive) With Attention-deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a phase 1b, multicenter, open-label, multiple-dose trial in pediatric subjects (4 – 12 years of age, inclusive) with a confirmed diagnosis of ADHD. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2021-03-09 |
| 290 | Validity and Reliability of Turkish Version of The Working Memory Questionnaire PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study was to determine the Turkish validity and reliability of ”The Working Memory Questionnaire” developed by Dr. Vallat-Azouvi. |
LÜTFIYE AKKURT; | 2021-03-03 |
| 291 | Diagnosis and Treatment Plan for Destructive and Conduct Disorder Children With Indifferent Traits and Emotion Regulation PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: For children with ADHD aged 4-10 at the time of enrollment, starting from preschool, focusing on apathy and emotional control, using psycho-behavioral measurements, EEG experiments, and eye tracking technology to evaluate and implement targeted Sexual intervention and six-month follow-up. Establish a diagnosis and treatment decision analysis model and psychological treatment plan for ODD/CD. |
JINGYI WU; | 2021-03-01 |
| 292 | Refining The Shared Decision Making Process Survey in ADHD Medication Decisions PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a retrospective observational survey study. We will survey a sample of adult parents or legal guardians who have a child who has been diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and who discussed ADHD treatment options for their child with a health care provider within the last 2 years. The main goal is to gather evidence of the validity and reliability of the Shared Decision Making Process scale. Secondary goal is to gather evidence on the quality of decisions parents make about their children with ADHD. A third goal is to assess the impact of a Decision Aid on participant knowledge of ADHD treatment options. Participants will be randomized to one of two arms: participants in the intervention arm will review a Decision Aid (patient educational tool) partway through the survey and those in the control arm will not receive any educational materials. All participants will complete survey that includes the Shared Decision Making process survey along with a few other measures. A subset of respondents will also complete a retest survey about two weeks after the initial survey. |
KAREN SEPUCHA; | 2021-02-24 |
| 293 | The Efficacy of Mindtesionis Measuring Attentional and The Startle Response Dysregulation in Children and Adolescents Suffering From Attention Deficit Disorder: With and Without Medication PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Double blind, placebo-controlled clinical study designed to evaluate Mindtension device and Protocol as a diagnostic tool in children diagnosed with ADHD |
IRIS MANOR; | 2021-02-23 |
| 294 | Placebo Effect in Children With Attention Deficit Disorder And/or Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: In Quebec, there has been an important increase of Attention Deficit Hyperactivity Disorder (ADHD) diagnosis since 2015. ADHD symptoms, related to behavioural and/or concentration difficulties, are very similar to other disorders symptoms, such as anxiety and depression, and have a significant impact on students’ academic success and future life. Adults (parent, teacher, coach) expectations towards a child’s abilities are consciously or unconsciously perceived by the child, influence his expectations of his own abilities, and thus his academic performance (Pygmalion effect). The child and his entourage’s expectations are therefore a major factor to consider, … |
GUILLAUME LÉONARD; | 2021-02-17 |
| 295 | The Effects of Methylphenidate (MPH) and Non-invasive Brain Stimulation (tDCS) on Inhibitory Control Children With Attention-Deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is comparing the effects of non-pharmacological intervention (transcranial Direct Current Stimulation, tDCS) with those of drug (methylphenidate, MPH) administration in children and adolescents with ADHD. The investigators hypothesized that tDCS would improve inhibitory control and visuo-spatial working memory as well as MPH. |
DENY MENGHINI; | 2021-02-08 |
| 296 | Development of A Technology-Enhanced Executive Functioning Skills Intervention for Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study develops and refines an online platform that will support clinician-directed behavioral and organizational skills intervention for adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) with input guided from key stakeholders during focus groups and interviews (phase 1), extended usability testing (phase 2), and a pilot randomized trial (phase 3) of the online tool used in conjunction with an organizational skills intervention. |
MELISSA DVORSKY; | 2021-02-03 |
| 297 | Investigating The Effect of The Temporal Adaptation Approach on Activity Self-Efficacy, Time Perception, and Daily Activity Routine with Executive Skills in Children with ADHD: A 1-Month Follow-Up Randomized Controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study investigates the impact of temporal adaptation interventions on children with Attention Deficit Hyperactivity Disorder (ADHD), focusing on activity self-efficacy, time perception, daily activity routines, and executive functions. The intervention aims to address the challenges ADHD children face in time processing abilities, which include understanding the concept of time, being punctual, initiating and completing daily activities independently, planning and completing long-term projects, using a calendar, … |
GONCA BUMIN; | 2021-02-03 |
| 298 | Mindfulness-Based ADHD Treatment for Children: A Feasibility Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-Deficit/Hyperactivity Disorder (ADHD) affects 11% of children and leads to adverse outcomes. Medications, while often effective in reducing certain ADHD symptoms, have many disadvantages, including misuse and side effects. Behavioral interventions do not have these adverse effects, but they are not as effective. Mindfulness is a candidate intervention for ADHD in elementary school children, … |
HEDY KOBER; | 2021-02-01 |
| 299 | Can A Supportive Sleep-Practitioner-led Intervention Lead to Improved Sleep, Wellbeing and Reduced Medication Prescribing for Children With Neurodevelopmental Disorders and Co-occurring Severe Sleep Difficulties? PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Around 80% of children with neurodevelopmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD) and autism are reported to have significant difficulties with sleep. This may be a problem with settling off to sleep, waking repeatedly in the night, or both. Often these children will be prescribed a medication called melatonin to help them sleep, but there is no strong evidence of its effectiveness in children, … |
SHEFFIELD CHILDREN’S NHS FOUNDATION TRUST | 2021-01-29 |
| 300 | The Use of Lisdexamfetamine in Clinical Practice at A Danish Child Psychiatric Outpatient Clinic Aimed at School Children (Age 7-13 Years) With Attention Deficit Disorders PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Aiming at improving clinical practice regarding the use of lisdexamfetamine for the treatment of ADHD in children, the investigators want to retrospectively map the clinical use of lisdexamfetamine at a specialised outpatient clinic located at Aarhus University Hospital, Denmark treating children aged 7-13 with Attention Deficit Disorders in the period from 2013 to 2019. The investigators will describe the changes in prescription practice in the period, reported side effects and reasons for selecting and discontinuing treatment with lisdexamfetamine. |
NANNA ROED SØNDERGAARD; | 2021-01-19 |
| 301 | Transcranial Photobiomodulation Therapy for The Treatment of Autistic Traits in Children and Adolescents With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving autistic traits in ADHD youth. |
TOLGA A CERANOGLU; | 2021-01-14 |
| 302 | Maternal and Offspring Outcomes in Pregnant Women With Pre-existing Atherosclerotic Cardiovascular Disease: A Nationwide Mother-Child Cohort Study PF:10 Related Papers Related Patents Related Grants Related Experts View Highlight: A growing body of evidence supports associations between cardiovascular health and adverse pregnancy outcome and between adverse pregnancy outcome and atherosclerotic cardiovascular disease and builds on the well-established pathways known to exist between cardiovascular health and atherosclerotic cardiovascular disease across the life course and intergenerationally. Furthermore, previous studies frequently lack comprehensive long-term follow-up, making it difficult to assess the enduring impacts of maternal cardiovascular health on postpartum outcomes and long-term maternal and child health. |
KI HONG CHOI; | 2021-01-01 |
| 303 | Improving Cognitive Function in Chinese Children With ADHD And/or RD Through Computerized Working Memory Training PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Prior research has found that children with attention-deficit hyperactivity disorder (ADHD) and reading difficulties (RD) are at an elevated risk of developing further cognitive deficits and developmental challenges. ADHD and RD are characterized by a deficit in working memory, which negatively affects learning and behavior. The main aims of this study were to design a working memory training app and examine its effectiveness through a 5-week training program in Chinese children with ADHD and/or RD. There were three experimental groups, with 26 participants in the ADHD group, 38 participants in the RD group, … |
EDUCATION UNIVERSITY OF HONG KONG | 2021-01-01 |
| 304 | Effect of Game-based High-Intensity Interval Training Program on The Executive Function of Children With ADHD: Protocol of A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Attention-deficit/hyperactivity disorder (ADHD) is a common developmental disorder in childhood, with a 5%-6% worldwide prevalence. Children with ADHD often demonstrate impaired executive function, which is closely related to the development of the commonly observed behavioral problems such as inattention, impaired inhibition, and hyperactivity. The purpose of this study is to examine whether a game-based high-intensity interval training (HIIT) program can improve the executive function of children with ADHD, … |
EDUCATION UNIVERSITY OF HONG KONG | 2021-01-01 |
| 305 | Serum Occludin and Zonulin Levels in Attention-deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The association between levels of zonulin and occludin and behavioral/emotional problems in children with ADHD are investigated. |
HICRAN DOGRU; | 2021-01-01 |
| 306 | A Double Blind, Placebo Controlled, Fixed-Flexible Dose Clinical Trial of Guanfacine Extended Release for The Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS). In addition, the study will establish the safety of GXR with a specific focus on metabolic effects. |
DEEPAN SINGH; | 2020-12-17 |
| 307 | Sub-study: Feasibility Trial of Adapted ESDM-informed Caregiver Coaching Delivered Remotely for Children With ASD and ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the feasibility of adapted ESDM-informed caregiver coaching in children with comorbid ASD and ADHD, who are between 36 and <132 months of age. There will be no study provided medication treatment in this study. Children will either be on ADHD medication prescribed by their own personal provider or will not be taking any ADHD medication (this will be documented by the study). The provided behavioral treatment will be eight ~60-minute sessions in ESDM-informed caregiver coaching delivered remotely through telehealth, ... |
LAUREN FRANZ; | 2020-12-16 |
| 308 | Antioxidant Therapy With N-acetylcysteine for Motor Behavior And/or Learning in Children With Neurofibromatosis Type 1 PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1 complication. In this project, the investigators will assess the safety and clinical benefit of N-acetylcysteine (NAC) as a pharmacological intervention in children with NF1. This drug choice is based on the recent findings from mouse models to study the central nervous system manifestations of NF1 at Cincinnati Children’s Hospital Medical Center (CCHMC). These findings revealed a role for myelin-forming oligodendrocytes in the control of nitric oxide synthases (NOS) and their product, … |
DONALD GILBERT; | 2020-12-15 |
| 309 | The Effect of Telerahabilitation on Fine Motor Skills and Writing Performance in Children With Attention Deficit and Hyperactivity Disorder: A Randomized Controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a randomized controlled study examining the effect of telerehabilitation on fine motor performance and handwriting difficulties experienced by children with attention deficit hyperactivity disorder. |
BUSRA KAPLAN; | 2020-12-01 |
| 310 | A Phase IV, Dose Optimized, Open Label, Evaluation of The Effect Foquest® (Methylphenidate HCl Controlled Release) on Sleep in Children Aged 6-12 With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effect of Foquest® on sleep, using actigraphy and sleep diaries, in children aged 6-12 compared to baseline on no medication. Sleep difficulties, including prolonged sleep onset latency and decreased total sleep time have a significant negative impact on the functioning of children. In adults, sleep deprivation may result in drowsiness and yawning. However, in children, this may manifest as mood and behavioural disturbances which may even mimic the classic symptoms of ADHD; hyperactivity, poor impulse control, … |
JUDY VAN STRALEN; | 2020-12-01 |
| 311 | The Effect of Guanfacine on Delirium in Critically Ill Patients PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Delirium in patients in the intensive care unit (ICU) is a common problem associated with increased mortality and morbidity, including increased hospital and ICU length of stay, greater hospital cost, increased ventilator days, and long-term cognitive disability. Various pharmacologic agents including dopamine antagonists, acetylcholinesterase inhibitors, melatonin, antipsychotics, alpha-2 agonists, and glutamate antagonists are used for treatment of delirium in the ICU despite the lack of clear evidence of efficacy.Since there is no evidence-based pharmacologic treatment of ICU delirium, current therapy is focused on non-pharmacologic prevention techniques and pharmacologic agents are used once delirium is established. Guanfacine, an alpha-2 agonist, … |
ANDREW BARKER; | 2020-11-23 |
| 312 | Multicenter Double-blind Placebo-controlled Parallel-group Randomized Clinical Trial of Efficacy and Safety of Prospecta in The Treatment of Attention Deficit/Hyperactivity Disorder in Children PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Purpose of the study: • evaluate the efficacy and safety of Prospecta in the treatment of attention deficit/hyperactivity disorder in children. |
MATERIA MEDICA HOLDING | 2020-11-20 |
| 313 | The Acute and Long-Term Effect of Home-Based Transcranial Direct Current Stimulation on Clinical Symptoms and Executive Function in Children With ADHD: A Randomized, Sham-Controlled TDCS and FNIRS Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to investigate the efficacy of twenty daily sessions of home-based tDCS over the left DLPFC, right IFG on attention and response inhibition in children with ADHD. Investigators hypothesize that multiple sessions of tDCS will induce a greater and long-term effect on attentional and/or inhibitory response in children with ADHD. In addition, this study seeks to get a better understanding of the mechanisms of tDCS using fNIRS. |
CHOI DEBLIECK; | 2020-11-05 |
| 314 | Open Trial of A Program to Support Parents of Children With Attention-deficit/Hyperactivity Disorder in Online Group Meetings PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Behavioral parent training is an evidence-based treatment for ADHD. The intervention can be implemented individually, or in groups. Currently, group-based parent training programs require considerable coordination, including ascertainment of a large physical space, the coordination of all families traveling to the same location at the same time, and the require for the provision of childcare. Innovations in online connectivity and ease of implementation of online support applications (e.g., Zoom) may reduce these barriers. However, it is necessary to investigate the feasibility and promise of the online approach to ensure it supports parents effectively. |
GREG FABIANO; | 2020-11-03 |
| 315 | Effect of Long-lasting EEG-Neurofeedback on Attention Control and Impulsivity in Adult Attention-Deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Mounting evidence suggests that closed-loop brain-training, commonly known as neurofeedback (NFB), may represent a new therapeutic opportunity for patients with Attentional Deficit/Hyperactivity Disorder (ADHD), which manifests as difficulties with attention and inhibitory control. In this context, the investigators have focused on an attention-enhancing form of NFB based on the EEG alpha rhythm, known to influence sensory detection and attention. In light of recent evidence showing that both attention and impulsivity can be modified with a single-session of alpha-NFB, the objective is to determine whether these effects stabilize in the long-term, after multiple, daily sessions of training at home. A short- … |
NADER PERROUD; | 2020-11-02 |
| 316 | The Brain Network Activity of Functional Tasks Performance By Magnetoencephalography for Children PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Investigate the differences in activation of brain networks during performing functional tasks for children with attention deficit hyperactivity disorder with developmental delays and typical development |
RU-LAN HSIEH; | 2020-11-01 |
| 317 | A Randomized-Controlled Trial: The Effectiveness of A Single-session of Mindfulness Based Cognitive Training on CVC and Core Symptoms in Children and Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders, with a pooled worldwide prevalence of 7.2% among children. Although medication and behavioral therapy, have been shown to be effective for reducing core symptoms, about 30% of patients with ADHD would not achieve the treatment response and symptomatic remission. Additionally, some children can experience sides effects related to medication. Therefore, other psychological approaches such as Mindfulness based interventions (MBIs) have been designed for the management of ADHD. Recent research showed that ADHD is associated with autonomic nervous system dysregulation, characterized by reduced vagally mediated-HRV, … |
ANDEEA ROBE; | 2020-10-30 |
| 318 | A Randomized Clinical Trial of Ba Duan Jin in Treatment of Attention Deficit Hyperactivity Disorder With Hyperactive-Impulsive Symptom PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is designed to test if Baduanjin training can reduce the hyperactive-impulsive symptoms of children with Attention deficit hyperactivity disorder (ADHD) compared to routine excise. Investigators will also evaluate if the Baduanjin training will positively affect Chinese Traditional Medicine (TCM) symptoms compared to controls and if these impacts are related to the change of the executive function. |
CHILDREN’S HOSPITAL OF FUDAN UNIVERSITY | 2020-10-24 |
| 319 | Effects of A Multiple Sclerosis Relapse Therapy With Methylprednisolone (MP) During Pregnancy on Offspring Cognitive Function, Stress Sensitivity, Behaviour and Functional and Structural Brain Development PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Introduction: Fetal exposure to glucocorticoids (GCs) used to induce fetal lung maturation in women threatened by premature labour is known to induce aberrations in brain development and stress sensitivity, cognitive dysfunction and neuro-psychiatric disorders in later life which all predict early brain ageing. Another common source of fetal GC exposure is the treatment of relapses in multiple sclerosis (MS), the most common neurological disease in young women. Despite the lack of studies, … |
FLORIAN RAKERS; | 2020-10-19 |
| 320 | Efficacy of Online Mindfulness-Based Intervention on Emerging Malaysian Chinese Adults With Attention Deficit/Hyperactivity Disorder: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to evaluate the efficacies of an online mindfulness-based intervention for emerging adults with ADHD in Malaysia. The investigators hypothesized that online mindfulness-based intervention may improve ADHD symptoms and executive functions of emerging adults with ADHD. |
PHEH KAI SHUEN; | 2020-10-15 |
| 321 | A Study With Multimodal Neurobiological Approaches to Explore The Interactions Between Monoamine Transporter Genes and Environmental Factors on Attention Deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Previous studies have demonstrated significant associations of attention-deficit hyperactivity disorder (ADHD) with monoamine transporter genes, including dopamine transporter gene (DAT1), norepinephrine transporter gene (SLC6A2), and serotonin transporter gene (SLC6A4) as well as the important role of environmental factors in the pathogenesis of ADHD. Hence, investigating how genes and environments interact with each other may contribute to the understanding of the pathophysiological mechanisms of ADHD. In this 3-year project, investigators will explore the complex gene-environment interplay in ADHD with multimodal neurobiological approaches, including neuropsychology, neuroimaging, and metabolites, in order to identify the crucial pathophysiological pathways from genes to the brain. |
NATIONAL TAIWAN UNIVERSITY HOSPITAL | 2020-09-19 |
| 322 | Stimulant Medication Effects on Auditory Sensitivity and Acoustic Reflex in Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aims of this study are to evaluate auditory sensitivity in teenagers with ADHD using acoustic reflex thresholds (ART) and to examine the effects of ADHD stimulant medication on ART. |
KYOKO NAGAO; | 2020-09-13 |
| 323 | Lifestyle Enhancement for ADHD Program (LEAP) Study 2 PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to increase physical activity (PA) in children with ADHD using a novel, family-based intervention that promotes PA within the context of evidence-based behavioral management training (BMT) for caregivers, enhanced with mobile health (mHealth) behavior change strategies. Primary Objective: To evaluate the primary effects of a 9-week, family-based intervention (Lifestyle Enhancement for ADHD Program – LEAP) to promote PA in young children with ADHD Secondary: To evaluate secondary effects of the LEAP program on child ADHD symptoms and executive functioning |
POOJA TANDON; | 2020-09-09 |
| 324 | Melatonin – Production and Release in Children and Adolescents With ADHD and Chronic Sleep Problems and Effects of Melatonin on Sleep PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Treatment with melatonin is often initiated on an insufficient basis as it has not been established prior to starting the treatment whether or not the child had delayed release of endogenous melatonin. At the clinic, it has furthermore been observed that the length of time a child experiences an effect of melatonin treatment varies substantially. In a clinical context, treatment with melatonin is used increasingly (www.Medstat.dk). However, … |
ALLAN HVOLBY; | 2020-09-01 |
| 325 | Comparative Study of The Personality Profile of Children and Adolescents With Attention Deficit Hyperactive Disorder (ADHD) With or Without Emotional Dysregulation PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) is frequently associated with emotional dysregulation (ED). ED is characterized by excessive and inappropriate emotional reactions compared to social norms, uncontrolled and rapide shifts in emotion and attention focused on emotional stimuli. According to research, there are strong correlations between personality traits and psychiatric disorder as ADHD. In a longitudinal study, the persistence of ADHD symptoms during adolescence is associated with high neuroticism, … |
UNIVERSITY HOSPITAL MONTPELLIER | 2020-09-01 |
| 326 | Short Structured Psychological Intervention for Adults With ADHD – A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effects of a novel psychological intervention for adult ADHD through a randomized controlled trial. Participants will be randomized to receive either a face-to-face manualized short psychological intervention, SAINT, or corresponding self-help material with limited access to therapist support. The main objective is to evaluate whether SAINT will show better outcomes on measures of ADHD-related symptoms, everyday function, and quality-of-life measures, when compared to the self-help material, and if any possible differences in outcomes are related to better treatment adherence in SAINT. |
BERKEH NASRI; | 2020-08-25 |
| 327 | Development and Assesment of TDApp1 An EHelath Tool to Make Participatory, Patient-centred and Automated Therapeutic Recommendations for Patients With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a 3-week open label, one group study to determine the agreement between the pharmacological treatment recommended by TDApp1 and the interventions recommended by relevant clinical practice guidelines. |
XAVIER CASTELLS; | 2020-08-10 |
| 328 | 2/2 Treating Mothers With ADHD and Their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will compare the effectiveness of combined parental stimulant medication and behavioral parent training (BPT) versus BPT alone on child ADHD-related impairment (primary outcome), child ADHD and externalizing symptoms, time to child stimulant prescription (secondary child outcomes) and parental ADHD impairment, parental ADHD symptoms, parenting, and BPT engagement (parental outcomes/target mechanisms). This study will also assess the care delivery context and develop an implementation approach for treatment of families with a parent with ADHD and a child with elevated ADHD symptoms via telehealth in primary care sites providing pediatric care. |
ANDREA CHRONIS-TUSCANO; | 2020-08-06 |
| 329 | A Naturalistic Study of Functional Impairment for Individuals With ADHD in The Early Morning and Late Afternoon/Evening Hours PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The objective of this study is to assess the burden and impact of ADHD impairment in the early morning and late afternoon/evening hours for adolescents and young adults. Functional impairments will focus on the currently identified areas of functional impairment in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5, American Psychiatric Association, 2013) – namely, social, academic, and occupational functioning. This is necessary for two reasons: (1) the current literature on ADHD impairment and functioning is concentrated within elementary school children; … |
GREGORY A FABIANO; | 2020-08-04 |
| 330 | Brain Tissue Integrity and Autonomic Function Alterations in Childhood Obstructive Sleep Apnea and Attention-deficit/Hyperactivity Disorder, and After Adenotonsillectomy PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Obstructive sleep apnea (OSA) and attention-deficit/hyperactivity disorder (ADHD) are two common, severe disorders in children. Unfortunately, pediatric OSA is closely associated with ADHD, and both diseases can cause cognitive impairment, behavior problems, and low academic performance. OSA can damage the brain and induce autonomic dysfunction, and then cause cognitive, behavioral, and quality-of-life problems. The presence of ADHD can further exacerbate these adverse effects of OSA. Therefore, … |
LI-ANG LEE; | 2020-08-01 |
| 331 | A Digital Health Solution for Improving Parent Adherence to Behavioral Treatment for ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to develop, refine and preliminarily test a novel and scalable digital health solution designed to address parent adherence barriers in daily life contexts and increase parent’s sustained use of evidence-based parenting strategies. |
LINDA PFIFFNER; | 2020-08-01 |
| 332 | Real-world Evidence of Duration of Adhansia XR for Treatment of ADHD (RE-DAX): An Open-label Pragmatic Study to Assess The Real-world Effectiveness of Adhansia XR in Treatment of Adult and Adolescent Patients With ADHD in The United States PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to investigate the treatment effectiveness of Adhansia XR at month-2 after initiation, and the effectiveness of Adhansia XR overall and when compared with the active comparator group (Concerta) over time. |
PURDUE PHARMA LP | 2020-07-30 |
| 333 | Linguistic Validation of The Childhood Bladder and Bowel Dysfunction Questionnaire (CBBDQ) for 5-12 Years Old in Korean PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study is to conduct a linguistic and cultural validation of the Children Bladder and Bowel Dysfunction (CBBDQs) for 5-12 years old from English to Korean. Once it has been validated into the Korean language, it will be a valuable source that will better serve patients with BBD symptoms in an outpatient setting and use in future clinical studies. |
KWANJIN PARK; | 2020-07-27 |
| 334 | Development of A Virtual Reality Application for The Diagnosis of Childhood ADHD: An Exploratory Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to develop an application in order to identify the most relevant cognitive and behavioral parameters for the diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) in conditions closer to reality |
JEAN-ARTHUR MICOULAUD-FRANCHI; | 2020-07-21 |
| 335 | Ocular-vestibular Biomarker Identification for ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study intends to establish a relationship between oculovestibular eye tracking measures, measures of ADHD, and medication prescribed for ADHD. |
BENJAMIN CHEYETTE; | 2020-07-16 |
| 336 | Study of The Duration and Efficacy of MYDAYIS on Adult ADHD Symptoms and Executive Function Throughout The Day Into The Early Evening PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric disorder characterized by problems with sustaining attention, organization, planning, procrastination, daydreaming, restlessness, impulsivity and hyperactivity.This is an outpatient study for subjects between the ages of 18-60, who have an Attention deficit hyperactivity disorder (ADHD) diagnosis meeting all inclusion criteria and not meeting any of the exclusion criteria. |
LENARD ADLER; | 2020-07-15 |
| 337 | Comparative Clinical Trial With Double-blind Randomized Sham Control and Additive Treatment Toward Efficacy of Mobile Neurofeedback for ADHD Youth : An Exploratory Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Objective: Verification of ADHD Treatment Effectiveness of Mobile Neurofeedback to Subjects of Child and Youth with ADHD. Method: Mobile Neurofeedback Program is implemented for 165 ADHD patients aged 8 to 15 to verify their effectiveness by conducting pre-post evaluation. Prior to the implementation of the intervention, we conduct a survey with demographic information, behavioral characteristics, clinical global impression, neuropsychological test, brain MRI, NIRS and EEG. The drug naive subjects are randomly assigned to the mobile Neurofeedback group or Sham control group. The subjects on medication are randomly assigned to the mobile Neurofeedback group or Sham control group, … |
BOOOG NYUNG KIM; | 2020-07-07 |
| 338 | Constitution of A Clinical, Neurophysiological and Biological Cohort for Chronic Sleep Disorders Responsible of Hypersomnolence PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Chronic sleep disorders result from multiple pathophysiological mechanisms and are often associated with severe hypersomnolence, responsible for major disability. Hypersomnolence may be secondary to sleep disturbances at night by sleep fragmentation, both overall in restless leg syndrome (RLS) or specific to slow or paradoxical sleep in parasomnias (sleepwalking, sleep behavior disorder). paradoxical). Attention-Deficit / Hyperactivity Disorder (ADHD) is another cause of secondary hypersomnolence, unsolved pathophysiology, leading to a major disturbance of alertness. More rarely, hypersomnolence may be primary (central hypersomnia), representing then the most severe form existing in humans. The best-known central hypersomnia is narcolepsy type 1 (NT1), … |
UNIVERSITY HOSPITAL MONTPELLIER | 2020-06-16 |
| 339 | Effects of Cognitive Occupational Therapy Interventions on Executive Functions in Children With Attention Deficit and Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder is a disorder in which children show insufficient attention span, hyperactivity and impulsivity according to their developmental level. It is stated that in the absence of rehabilitation, the child’s social and academic functionality gradually deteriorates, … |
REMZIYE AKARSU; | 2020-06-15 |
| 340 | A Phase 1b, Multicenter, Open-label, Multiple Ascending Dose Trial to Assess The Pharmacokinetics, Safety and Tolerability of Centanafadine Extended-release Capsules After Oral Administration in Pediatric Subjects (4 to 12 Years, Inclusive) With Attention-deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This trial will evaluate the pharmacokinetics, safety, and tolerability of centanafadine in pediatric subjects with ADHD. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2020-06-11 |
| 341 | Assessment of Probiotic Strain Lactobacillus Acidophilus LB Supplementation As Adjunctive Management of Attention-deficit Hyperactivity Disorder in Children and Adolescents: A Randomized Controlled Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD is a neurodevelopmental disorder characterized by persistent symptoms of inattention and/or hyperactivity and impulsivity that are present before age 18. These symptoms must be evident across ADHD treatment is currently based on a multimodal approach with the combination of psychotherapy and pharmacotherapy, … |
REHAM IBRAHIM; | 2020-06-09 |
| 342 | Investigation of The Relationship Between The Use of Social Media and Gross Motor Function, Hand Function, Communication, Eating and Drinking and Visual Function Children With Cerebral Palsy in Turkey PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to examine the relationship between screen usage time and problematic social media use in children with Cerebral Palsy (CP) with motor function, hand function, speech and vision function. |
MINTAZE KEREM GUNEL; | 2020-06-01 |
| 343 | Willkommen Mutterglück: A Controlled Trial of Internet Based Cognitive Behavioural Therapy (CBT) for Pregnant and Postpartum Women With Depression and Anxiety PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This intervention study aims to evaluate the effectivity of web-based cognitive therapy in reducing depression and anxiety in pregnant and postpartum women. Moreover, it aims to assess treatment feasibility and usability of the treatment in the same population. After an initial screening to determine the eligibility to participate, all participants fulfilling the inclusion criteria will receive their personal access login in order to start the intervention. |
RITA AMIEL CASTRO; | 2020-06-01 |
| 344 | Randomized Controlled Trial of Web Based Tools to Improve Medication Continuity in Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Medication is an efficacious treatment strategy for adolescents with attention-deficit/hyperactivity disorder (ADHD), however use significantly declines during adolescence when the consequences of ADHD are most severe (e.g. dropping out of school, delinquency, … |
CHILDREN’S HOSPITAL MEDICAL CENTER CINCINNATI | 2020-06-01 |
| 345 | A Randomized Controlled Trial of Internet Based Cognitive Behavioural Therapy (CBT) Versus Treatment As Usual (TAU) for Pregnant Women With Symptoms of Depression Related Papers Related Patents Related Grants Related Experts View Highlight: Most depression during pregnancy is undetected and untreated although it is known to be harmful both to the woman herself and her future child. When these mental disorders are detected, psychotherapies remain difficult to access, especially in primary care, despite being effective.Also, prenatal depression is known to be a strong risk factor for postnatal depression and may prejudice the mother-infant relationship. This leads us to the following question: Will individual Cognitive Behavioral Therapy (CBT) delivered online be a more effective treatment for symptoms of depression in pregnant women, … |
MARTIN KAMMERER; | 2020-06-01 |
| 346 | A Self-guided Internet-delivered Intervention for Adults With ADHD: Study Protocol for A Micro-randomized Trial Investigating The Use of Reminders PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Background: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by symptoms of inattention and/or hyperactivity/impulsivity that are persistent across situations and time. ADHD in adulthood, with an estimated prevalence of 2 – 3 %, is associated with challenges that may have severe consequences on their daily life functioning. Still, the availability of evidence-based psychological interventions is limited. Interventions delivered over the Internet is promising, because it may increase the availability of effective psychological interventions for a larger group of adults with ADHD. However, … |
HAUKELAND UNIVERSITY HOSPITAL | 2020-05-20 |
| 347 | Cross-sectional Study Assessing The Contribution of Attachment and Educational Practices in The Expression of ADHD in School-aged ADHD Children and Control Group PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD is a neurodevelopmental disorder characterized by the presence of persistent signs of associated hyperactivity-impulsivity and/or inattention that impair the child’s functioning or development. The involvement of genetic factors has been shown in numerous studies. Other studies have also highlighted the contributions of parent-child interaction in the development, expression and persistence of symptoms.However, the mechanisms by which parenting practices and attachment may influence ADHD symptoms remain unclear. The aim of this study is to evaluate the influence of attachment style of the child, … |
JEAN-FRANÇOIS WYLOCK; | 2020-05-15 |
| 348 | Effect of Bifidobacterium Bifidum (Bf-688) on Clinical Characteristics and Gut Microbiota in Attention-deficit/Hyperactivity Disorder: A Double-blind Randomized-control Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder. Gut microbiome dysbiosis may be associated with the pathophysiology of ADHD. Investigators previously found the relative abundance of Sutterella stercoricanis were increased and Bifidobacterium bifidum were decreased in the ADHD group. Investigators hypothesize that ADHD patients receiving supplementary Bifidobacterium bifidum (Bf-688) is able to increase the proportion of Bf-688; inhibit the proportion of Sutterella; and improve ADHD symptoms. |
WANG LIANG-JEN; | 2020-05-14 |
| 349 | The Efficacy of A Single Dose Clonazepam Compared With The Intermittent Diazepam to Prevent Recurrent Febrile Seizures in Queen Sirikit National Institute of Child Health PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To study the efficacy and safety of single dose clonazepam compared with intermittent oral diazepam for prevention of recurrent febrile seizures in children who had three or more febrile seizures. |
KULLASATE SAKPICHAISAKUL; | 2020-05-13 |
| 350 | A Randomized, Double-blind, Placebo-controlled, Crossover Study to Investigate The Safety and Efficacy of Qualia Mind on Cognition in A Healthy Population PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a randomized, double-blind, placebo-controlled, crossover study designed to investigate the safety and efficacy of Qualia Mind on cognition in a healthy adult population between ages of 18 and 75 years. Qualia Mind is a nootropic supplement containing a complex mixture of vitamins, minerals, amino acids, choline donors, and herbal ingredients. These components have been demonstrated to exert their cognitive effects through distinct mechanisms of action involving cholinergic, glutamatergic, and dopaminergic receptor signalling; neuroplasticity; and modulation of cell membrane structure and metabolism. |
RUPAL TRIVEDI; | 2020-05-12 |
| 351 | Clinical Evolution and Parenting in Children and Adolescents With Autism Spectrum Disorder or Attention Deficit Hyperactivity Disorder Quarantined Because of Covid-19 Outbreak PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: In response to the coronavirus disease 2019 (covid-19) outbreak, the home confinement of the population ordered by governments in many countries raise questions about its impact on individuals’ physical and mental health in the short and longer term. In children, reduced physical activity, changes in lifestyle, disturbances in sleep patterns, lack of in-person contact with peers, poor or inadequate understanding of health risks may be risk factors of anxiety, stress, fatigue, sleep disorders (Brooks et al, 2020; Wang et al, 2020; Sprang et al, 2013). These problematic effects could be modulated by social factors (housing in urban or rural areas, … |
MALIKA DELOBEL-AYOUB; | 2020-05-05 |
| 352 | Cortical Excitability and Role of RTMS in Nicotine Use Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Cortical excitability and role of repetitive transcranial magnetic stimulation in nicotine use disorder. Estimation of cortical excitability in heavy smoker patients and determination of role of repetitive transcranial magnetic stimulation for reducing nicotine craving. |
AMIRA MOHEB; | 2020-05-04 |
| 353 | The 9-month Follow-up Study for The Patients of Illicit Substance Use Disorder After Receiving The Different Psychosocial Intervention PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: The patients will be diagnosed according to DSM-5, the severity of individual substance use disorder will be assessed, and the plan of treatment will be provided. The treatment will be determined by the diagnosis and severity of addiction, the mood or psychiatric comorbidities, the hyperactivity or attention deficit, alcohol addiction, and etc. The motivational enhancement interview, the individual psychotherapy, the group psychotherapy, the family therapy will be provided by our team members. In order to evaluate the efficacy of the different therapy, … |
FRANK HUANG-CHIH CHOU; | 2020-05-01 |
| 354 | Study of The Link Between Psychosocial Treatments and The Need of Pharmacological Treatments in Children With Attention Deficit Hyperactivity Disorder : A Retrospective Online Study for Parents PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The Attention Deficit and Hyperactivity Disorder (ADHD) is a frequent disorder in children and adolescents. The diagnosis is clinical with the input of several informants (child, family, teachers, …). ADHD is a risk factor for academic difficulties, school dropout, social isolation, injury, oppositional behaviour. In school-age children and adolescents having moderate to high or persistent impairment despite psycho-educational support and environmental modification, the first-line treatment is methylphenidate. Group or individual cognitive behavioural therapy for parents and/or children and adolescents is recommended for co-occurring disorders and persistent impairment. In France, … |
CHRYS AMIEL; | 2020-05-01 |
| 355 | Therapeutic Effects of Interactive Attention Training on Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Using a double-blind, randomized controlled design to investigate the therapeutic effects of interactive attention training for children with Attention Deficit Hyperactivity Disorder who are receiving conventional rehabilitation programs due to developmental delay. |
RU-LAN HSIEH; | 2020-05-01 |
| 356 | Methodology of CoCo 20 : A Longitudinal Follow-up Study of The Paediatric Population and Their Families During and After The Coronavirus Pandemic and The Confinement PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: In the context of a viral outbreak and of widespread quarantine measures, a significant increase in psychological disorders, such as stress or fear behaviours, had previously been observed. This distress has been described on adults, but no data have been collected yet for paediatric populations. After a traumatic event, children and adolescents may present several clinical consequences, the most common being Post-Traumatic Stress Disorder (PTSD). Moreover, PTSD in children and adolescents is often associated with comorbid disorders, such Attention Deficit Hyperactivity Disorder, depression, attachment and anxiety disorders, … |
FONDATION LENVAL | 2020-04-27 |
| 357 | Investigating The Effectiveness of Probiotic Supplement in Improving Attention Deficit Hyperactivity Disorder Symptoms in Children PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To study the effects of probiotic supplement in children with Attention-deficit hyperactivity disorder (ADHD),40 patients will be randomly allocated to two groups of intervention and placebo. The intervention and the placebo group will be prescribed with 1 capsule of probiotics and placebo for 8 weeks, respectively. Treatment efficacy will be assessed via administrating the Conners’s rating |
AZITA HEKMATDOOST; | 2020-04-20 |
| 358 | Examining The Impact of Mightier Play on Common Pediatric Symptoms in An Uncontrolled Environment PF:6 Related Papers Related Patents Related Grants Related Experts View Highlight: Mightier is a digital mental health tool that uses video game-based heart rate biofeedback to teach emotion regulation. The primary goal of this study is to replicate results from original clinical trials, demonstrating that playing Mightier at home improves common symptoms associated with emotional dysregulation. Participants will be caregivers of children who are using Mightier, a video-game based heart rate biofeedback intervention. Caregivers will be asked to complete a short survey about their child’s emotions and behaviors prior to their child’s first play and then complete that survey two more times, … |
ALYSSA PEECHATKA; | 2020-04-10 |
| 359 | Non-interventional Trial to Investigate The Change of Psychopathological Markers of Affective Dysregulation (AD) in Children With Attention Deficit Hyperactivity Disorder (ADHD) Treated By Guanfacin, A Pilot Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Early onset, high prevalence and persistence, as well as developmental comorbidity make affective dysregulation (AD) in childhood one of the most psychosocially impairing and cost-intensive mental conditions. Despite continuous research, … |
MED. ROBERT WALTEREIT; | 2020-04-01 |
| 360 | Αn Information System for Symptom Diagnosis and Improvement of Attention Deficit Hyperactivity Disorder (ADHD360) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD360 will be an innovative integrated platform for early ADHD diagnosis and intervention against its symptoms. In the core of the platform design there will be a serious game along with a mobile application to monitor behavior and to evaluate the intervention. |
PANOS BAMIDIS; | 2020-04-01 |
| 361 | Improving Rates of Behavioral Treatment in Preschoolers Through Mehealth for ADHD Software PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary goal of the proposed project is to test the feasibility of parent and teacher/childcare providers use of the ADHD web portal-integrated behavioral treatment modules with preschool children with ADHD in order to improve the access to and the integrity of evidence-based behavioral treatment strategies for young children with ADHD. |
TANYA FROEHLICH; | 2020-03-27 |
| 362 | Relationships in Good Hands Trial: Clinical and Cost-effectiveness of Dyadic Developmental Psychotherapy for Abused and Neglected Young Children With Maltreatment-associated Problems and Their Parents PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The research question is: Can the research recommend better ways for social care and health services to work work together to help adoptive and foster families? Can a therapy called DDP improve the mental health of 5-12 year old fostered or adopted children? Is DDP worth the commitment families need to give to it – and the extra cost to the services that deliver it? More than half of adopted or fostered children in the UK have mental health problems including ADHD (i.e. hyperactivity, impulsive behaviour and poor concentration), … |
HELEN MINNIS; | 2020-03-01 |
| 363 | THE EFFECT OF THE COGNITIVE ORIENTATION TO DAILY OCCUPATIONAL PERFORMANCE (CO-OP) APPROACH IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER ON MOTOR PERFORMANCE AND EXECUTIVE FUNCTIONS: A RANDOMIZED CONTROLLED STUDY PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention deficit and hyperactivity disorder (ADHD) is a behavioural and neurodevelopmental disorder that can affect behavioural, emotional, academic, social, and cognitive functions and is not age-appropriate. The prevalence of ADHD among school children is reported to be 3%-11%. Children with ADHD have difficulties paying attention to details, concentrating, completing tasks and following instructions, among other social and academic challenges. In children with ADHD, insufficient activity in the prefrontal regions of the brain has been evidenced, which is linked to executive function skills. Such children have difficulties in performing executive functions that require a high level of cognitive skills, … |
SEDANUR GÜRLEK; | 2020-03-01 |
| 364 | The Effects of Combined Exercise Program in Children Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) is a heterogeneous neurodevelopmental disorder characterized by carelessness, hyperactivity and impulsivity, in which genetic, social and physical factors play an important role. Few studies have revealed the physical activity levels and importance of children with ADHD, but there is no consensus on the components of the physical activity program such as intensity, frequency, and severity. The aim of the present study is to investigate the effect of combined exercise training on motor proficiency, physical fitness and cognitive status in children with ADHD. |
ARZU DEMIRCIOĞLU; | 2020-02-28 |
| 365 | Peer Professionals to Increase Capacity to Treat ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this 1-year project is to evaluate a service delivery model by peer support organizations to increase mental health service access and utilization for children at risk for attention-deficit/hyperactivity disorder (ADHD) from socioeconomically disadvantaged, urban communities. Behavioral parent training [BPT] currently delivered directly by Family Peer Advocates (FPAs), will be evaluated in a sample of 18 families on child outcomes. |
ANIL CHACKO; | 2020-02-26 |
| 366 | Acute Effects of Prescription Stimulant Medication on Cognition and Mood in College Students With and Without ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent stimulant misuse among college students without ADHD. The working hypothesis is that stimulants, compared to baseline and placebo conditions, will improve executive functioning for college students with ADHD but not for college students without ADHD. Improvements on executive functioning measures (e.g., CPT-IP, Spatial Span) will be examined through 2 (ADHD vs. non-ADHD) x 3 (Baseline, Placebo, … |
CYNTHIA M HARTUNG; | 2020-02-11 |
| 367 | Nutritional Intervention in Children With ASD And/or ADHD: Randomized Controlled Trial With Probiotics PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Based on alterations in the intestinal microbiota in children with ASD and the high comorbidity between ASD and ADHD, the aim of this project was to assess whether the administration of probiotics with strains related to the production of the neurotransmitters dopamine and GABA had a positive effect on social behavior, attention, and behavior. |
JOSEFA CANALS SANS; | 2020-02-03 |
| 368 | Traditional Chinese Medicine (TCM) Pediatric Massage for The Treatment of Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Preschool Children: A Pilot Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This project is designed to preliminarily assess the effects and feasibility of parent-delivered TCM pediatric massage for ADHD symptoms in preschool children. |
YEUNG WING FAI; | 2020-02-01 |
| 369 | An Open-Label Extension Study to Evaluate The Long-Term Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule) in Adults With Attention-Deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Open label, flexible dose, long-term multicenter study of safety and efficacy of SPN-812 in adult ADHD patients |
SUPERNUS PHARMACEUTICALS | 2020-01-23 |
| 370 | Psychometric Validation of The Competitive Attention Test (CAT) : Simultaneous and Separated Measures of Voluntary and Involuntary Attention PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This project aims at validating a new neuropsychological test to measure voluntary and involuntary attention for clinical use to diagnose attentional deficits. This project proposes: – a test-retest procedure in healthy subjects aged from 6 to 90 year-old; – testing in attention deficit hyperactivity disorder (ADHD) patients before psychostimulant treatment; – testing in attention deficit hyperactivity disorder (ADHD) patients before psychostimulant treatment. |
HOSPICES CIVILS DE LYON | 2020-01-21 |
| 371 | SLEEP – An Intervention With Weighted Blankets for Children With Attention Deficit Hyperactivity Disorder (ADHD) and Sleep Problems PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of the study is to evaluate a sleep intervention with weighted blankets for children with ADHD and sleep problem regarding health-related outcomes, sleep, and cost-effectiveness. The study is an RCT with cross-over design. The participants will be randomized to start with an active or placebo blanket, and then change blankets during the 16 week study period. |
INGRID LARSSON; | 2020-01-01 |
| 372 | The Efficacy of The Psychological Resilience Program for The Adolescent Girls Who Are Victims of Sexual Abuse PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: İn this study, it was aimed to examine the effectiveness of the psychological resilience program for adolescent girls after sexual abuse.This study is a randomized controlled trial. |
GÜLGÜN DURAT; | 2020-01-01 |
| 373 | Efficacy of Mobile Neurofeedback for Adult Attention-Deficit/Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is an assessor-blind, parallel-group, controlled trial to evaluate the benefit of home-based training with a low-cost, mobile neurofeedback system (Myndlift) in adults with ADHD. Randomized controlled trials have shown significant benefit for neurofeedback, including persistent effects without the side effects of psychostimulants (i.e., diminished appetite, insomnia, anxiety, irritability). However, standard application requires clinic visits and significant expense, limiting training frequency and compromising potential efficacy. Additionally, extant evidence for efficacy comes almost exclusively from children and adolescents, with very few studies in adults. The present trial will measure the ability of home-based neurofeedback using a low-cost, … |
TAMIR EPSTEIN; | 2019-12-22 |
| 374 | Fish Oil Affects Cognition and ADHD Symptoms in Adults With Autism Spectrum Disorder: A Randomized Crossover Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The prevalence of autism spectrum disorder (ASD) is rising and was estimated to have a prevalence of around 1.5% in developed countries in 2016. ASD is characterized by impairments in social interaction and repetitive behavior and is associated with executive dysfunction such as impaired working memory, inhibition, and flexibility. Furthermore, ASD is often associated with multiple comorbidities such as attention-deficit/hyperactivity disorder (ADHD), depression, and anxiety. Systematic reviews and meta-analyses indicate that fish oil (FO) supplementation improves attention, impulsivity, … |
LOTTE LAURITZEN; | 2019-12-10 |
| 375 | Randomized Study of Personalized Cognitive Training With Virtual Reality Technology (The Secret Trail of Moon) Versus Online Therapeutic Chess Cognitive Training Versus Usual Treatment (TAU) in Attention Deficit Hyperactivity Disorder (ADHD):a Clinical Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Blackground: Currently research on alternative forms of cognitive training in patients diagnosed with ADHD is gaining interest. Especially, the use of Virtual Reality video games. Our team has developed an innovative video game based on Virtual Reality, The Secret Trail of Moon (TSTM) as a cognitive tool to train 5 main areas of deficit in patients with ADHD. It is superiority study comparing TSTM with therapeutic chess and control group. Methods: This study is prospective, unicentric, randomized with a control group. 105 patients diagnosed with ADHD and pharmacologically stable, … |
HILARIO MANUEL BLASCO FONTECILLA; | 2019-12-09 |
| 376 | A Live-Online Mindfulness-based Intervention for Families of Children With Epilepsy: Making Mindfulness Matter© Randomized Control Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Epilepsy is a debilitating condition characterized by spontaneous, unprovoked seizures. Up to 80% of children with epilepsy (CWE) may face cognitive, psychiatric, and/or behavioral comorbidities with significant unmet mental health needs. Mindfulness-based interventions may provide an ideal vector to target unmet mental healthcare needs in patients with epilepsy and their families. The investigators propose the Making Mindfulness Matter© (M3) program as an intervention to improve health related quality of life and mental-health for CWE and their parents. M3 is live-online parent and child program that incorporates mindful awareness, social-emotional learning skills, neuroscience, … |
KATHY NIXON SPEECHLEY; | 2019-12-02 |
| 377 | Impact of Adult With Attention Deficit / Hyperactivity Disorder on Professional Activity, A Prospective Cohort Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit/Hyperactivity Disorder (ADHD), which is common and well known in children, persists into adulthood in more than 60% of cases, with significant impact on quality of life. Professional domain is particularly impaired. The investigators hypothesize that ADHD symptoms causes professional difficulties, on the emotional, cognitive, … |
SÉBASTIEN WEIBEL; | 2019-12-01 |
| 378 | Dose Clinical Trial of Guanfacine Extended Release for The Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome Related Papers Related Patents Related Grants Related Experts View Highlight: This is a placebo-controlled clinical trial to assess the utility of Guanfacine Extended Release (GXR) in the management of patients with Prader Willi Syndrome (PWS) who have significant aggression or self-injury. The purpose of this trial is to establish the safety of GXR with a specific focus on metabolic effects. |
DEEPAN SINGH; | 2019-12-01 |
| 379 | A Phase II Tolerability and Efficacy Study of PDC-1421 Treatment in Adult Patients With Attention-Deficit Hyperactivity Disorder (ADHD), Part I Related Papers Related Patents Related Grants Related Experts View Highlight: The primary objective of this trial was to determine the effective doses and treatment period of PDC-1421 Capsule in subjects with ADHD. The secondary objective was to evaluate the safety of PDC-1421 Capsule in subjects receiving PDC-1421 at various dose levels. |
BIOLITE | 2019-12-01 |
| 380 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Flexible-Dose Study of The Efficacy and Safety of SPN-812 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the efficacy and safety of SPN-812 (Viloxazine extended-release capsules; 200-600 mg) in adults 18-65 years of age with Attention-Deficit/Hyperactivity Disorder (ADHD). |
SUPERNUS PHARMACEUTICALS | 2019-11-20 |
| 381 | Reducing Disparities in Behavioral Health Treatment for Children in Primary Care PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to address a decisional dilemma faced by health system officials, policy makers, and clinical leaders: Does it make sense to integrate behavior therapy into primary care practice to treat children with ADHD from low-income settings? More specifically, does integrated care improve access to services and patient-centered outcomes for underserved children with ADHD? Participants will be randomly assigned to one of two groups: Behavior therapy integrated into primary care (Partnering to Achieve School Success; … |
JENNIFER A MAUTONE; | 2019-11-01 |
| 382 | Pilot Study Evaluating The Effectiveness of Neurofeedback Training in The Improvement of Cognitive Functions of The Elderly With Mild Cognitive Impairment PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effects of SMR neurofeedback training on cognitive performance and electrical brain activity in elderly with cognitive impairment. |
ANNE-SOPHIE RIGAUD; | 2019-11-01 |
| 383 | A Pilot Phase 2a, Multicenter, Open-label, Single-dose Trial to Assess The Pharmacokinetics of Centanafadine Extended-release Capsules After Oral Administration in Pediatric Subjects (9 to 12 Years, Inclusive) With Attention-deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: With the pharmacokinetics (PK) of centanafadine currently being evaluated in adults. The PK of extended-release centanafadine may differ in children compared to adults due to physiological differences in the gastrointestinal tract. The information in this trial will support pediatric dose selection in future trials. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2019-10-07 |
| 384 | Attention Deficit/Hyperactivity Disorder (ADHD) Medications in Japan: A Retrospective Cohort Study of Label Compliance PF:8 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to document the extent of on-label and off-label use of Methylphenidate (MPH) (Concerta), MPH (Ritalin), Atomoxetine (ATO), and Guanfacine (GFC) in Japan. |
JANSSEN RESEARCH & DEVELOPMENT | 2019-10-01 |
| 385 | Prevalence of Tics in Childern With Acute Deficit Hyper Activity Syndrom PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Tics have been defined as sudden, rapid, recurrent, non-rhythmic, stereotyped, involuntary movements or vocalizations. Motor tic can be either simple or complex, depending on whether one or several muscle groups are simultaneously or concurrently affected. Motor tics commonly include behaviours such as eye blinking, lip-licking, or mouth opening. It can also involve more complex movements like facial grimacing ,head movements , shoulder shrugging or combinations of these.Vocal or phonic tics are involuntary sounds that include throat clearing, coughing, barking, sniffing, … |
AHMED ATEF HASSOBBA; | 2019-10-01 |
| 386 | Catecholamine and Cognitive Response to Exercise in Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study will investigate catecholamines responses, and cognitive effects of exercise in children with attention deficit hyperactivity disorder, and the effect of exercise training on these measures. |
DAN NEMET; | 2019-10-01 |
| 387 | Establishment of A Diagnosis and Treatment System for Information Processing Damage in Children With Obstructive Sleep Apnea Hypopnea Syndrome PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common childhood sleep disorder with an incidence of 3% . Studies have confirmed that OSAHS can cause multiple systemic dysfunction in children, especially affecting cognitive function . Cognitive function is an important part of human advanced neurological activities, including neurobehavioral functions such as orientation, attention, concentration, alertness, behavior, execution, etc., as well as intelligence and verbal functions such as memory, learning, calculation, language, understanding, judgment, and logic. Reasoning and many other aspects. Impaired cognitive function often means poor academic performance, which is the most concern of parents. However, … |
SECOND AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY | 2019-10-01 |
| 388 | Driving Performance in Patients Aged 18 to 25 Years With Attention-Deficit/Hyperactivity Disorder (ADHD) After A Single-Dose of Amphetamine Extended-Release Tablets: A Pilot, Double-Blind, Placebo-Controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to assess the effect on driving performance of a single dose of amphetamine extended-release tablets (20 mg/tablet) compared with placebo at 45 minutes and 10 hours post-dose in young adults with ADHD. |
JOSEPH BIEDERMAN; | 2019-10-01 |
| 389 | Development of A Mobile App for An Executive Functioning Intervention for Adolescents PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study develops an initial prototype of a mobile tool that will support clinician-directed behavioral/organizational skills treatment for adolescents with Attention Deficit Hyperactivity Disorder (ADHD) with input guided from key stakeholders. |
MELISSA R DVORSKY; | 2019-09-30 |
| 390 | A Phase IV, Real World, Open-label, Multi-centre Study on The Use of FOQUEST® (Methylphenidate Hydrochloride Controlled-release Capsules) for The Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in Pediatric and Adult Patients PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a four-month, phase IV, open-label study of ADHD symptomatology and functional outcomes in pediatric (6 to 17 years old) and adult (≥18 years or older) patients with ADHD treated with FOQUEST or VYVANSE. |
PURDUE PHARMA CANADA | 2019-09-19 |
| 391 | Eat2beNICE Vitamins and Nutrients As Supplementation for Impulsivity, Irritability, and Compulsivity PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Impulsivity, irritability and compulsivity are cross-disorder symptom domains, which affect a significant proportion of adolescents. Predominately as part of attention deficit hyperactivity disorder (ADHD) but also as symptom domains without a diagnosis of ADHD, impulsivity and irritability cause serious burden. Furthermore, treatment options and their effects are limited. Previous studies with different study designs assessing micronutrients for the treatment of impulsivity / ADHD in children and adults have reported positive benefits as well as a very good tolerability. However, more research is required; in particular controlled studies with adolescents, … |
ALEXANDER HAEGE; | 2019-09-18 |
| 392 | Effect of Attention Deficit Hyperactivity Disorder Knowledge Improvement Program on Male Primary School Teachers in Abha City: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The study aims to assess the impact of implementing ADHD knowledge improvement program on male primary school teachers’ knowledge regarding ADHD in Abha City, Saudi Arabia. |
ABDULLAH MOHAMMED ALSHEHRI; | 2019-09-16 |
| 393 | SKOLKONTAKT – Social Skills Training in A School Setting, A Randomized Controlled Pilot PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study investigates the behavioral effects of an adapted manual-based social skills training program (SKOLKONTAKT) for the mainstream education plan delivered by school personnel, with pupils (15-20 years) with social-communication needs; either formally diagnosed (i.e. autism spectrum disorders or ADHD) or teacher-reported subclinical difficulties. N=40 are recruited from a community school in the Stockholm area (Sweden). |
SVEN BÖLTE; | 2019-09-02 |
| 394 | Group-Based Cognitive-Behavioral Therapy for Adults With Attention-Deficit/Hyperactivity Disorder Inattentive Presentation: Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Using a randomized controlled design, standard treatment of group cognitive-behavioral therapy (CBT) according to the Hesslinger protocol is compared to a newly developed group treatment specifically designed for adult patients with ADHD inattentive presentation (ADHD-I) called CBT for ADHD-I (CADDI). Research setting is psychiatric outpatient clinics. Research hypotheses include: 1. The CADDI protocol is more effective than standard treatment in terms of behavioral activation, procrastination, depressive symptoms, functional impairment, and quality of life, 2. Is equally effective in terms of ADHD symptoms, 3. Is more appreciated and tolerable, … |
BENJAMIN BOHMAN; | 2019-09-01 |
| 395 | The Efficacy of Goal Focused, Non-Pharmacological Treatment for Persons With ADHD/ADD. A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study aims to improve the understanding of non-pharmacological treatments of ADHD with a particular emphasis on coping with executive problems. Executive functions can be defined as those abilities necessary to formulate goals, carry them out effectively and enabling a person to engage successfully in independent, purposive, self-serving behavior. The intervention consists of: 1. Eight psycho-educative group sessions focusing on Goal Management Training (GMT), a method aiming to enhance goal directed behavior, … |
KJERSTI TRAELAND HANSSEN; | 2019-08-15 |
| 396 | Development of A Novel Transdiagnostic Intervention for Anhedonia – R33 Phase PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The overall goal of this project is to develop a novel transdiagnostic treatment for anhedonia, called Behavioral Activation Treatment for Anhedonia (BATA), using ultra-high field functional neuroimaging. There is a critical need for a validated treatment that specifically targets anhedonia, and this project will evaluate the effects of this new treatment on anhedonia and will establish how this treatment impacts brain systems that mediate reward processing, clinical symptoms of anhedonia, functional outcomes, and behavioral indices of reward processing. This work will also identify brain targets by which future novel anhedonia treatment may be evaluated. |
GABRIEL S DICHTER; | 2019-08-01 |
| 397 | The Neuroprotective Effects of Methylphenidate and Atomoxetine in Children With Attention Deficit Hyperactivity Disorder: A Lipidomic Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: 1. To identify the difference in the lipidomic profiles between ADHD and controls; 2. To examine the effects of methylphenidate and atomoxetine on the lipidomic profiles in ADHD, and the relationship between medication-related changes in the lipidomic profiles and medication-related improvements in the behavioral symptoms and neuropsychological functions; 3. To map medication-related lipidomic biomolecules to their respective metabolic pathways to identify the underlying mechanisms of neuroprotective effects of methylphenidate and atomoxetine. |
CHI-YUNG SHANG SHANG; | 2019-08-01 |
| 398 | Reliability Testing of A Non-invasive, Pain-free, Taste-based Assessment Approach to Lidocaine Effectiveness PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This work will assess the reliability of a simple painless test for the effectiveness of the commonly used local anesthetic lidocaine |
MICHAEL SEGAL; | 2019-08-01 |
| 399 | Oral Findings In A Group of Egyptian Children With Attention Deficit Hyperactivity Disorder: A Cross-Sectional Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder is the most common childhood neuro-developmental disorder that is characterized by inattention, hyperactivity, and impulsivity. These symptoms last till adulthood in 65% of cases. ADHD has been reported to have a worldwide prevalence of 5.3% and it is more common in boys than in girls (Ghanizadeh 2008; Serra-Negra et al. 2012 and Shooshtari et al. 2013) The symptoms of ADHD are generally treated through behavioral therapy, with or without pharmacological intervention. Medications prescribed are commonly divided into stimulant or non-stimulant drugs. The stimulant medications (such as methylphenidate and amphetamines) have been implicated in adverse oral effects, … |
SARA GABER HUSSIEN; | 2019-08-01 |
| 400 | An Analog Classroom Study: Efficacy and Safety of SPN-812 in Children With Attention-Deficit/Hyperactivity Disorder Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the efficacy and safety of SPN-812, an extended-release formulation of viloxazine, compared to placebo in children in an analog classroom setting. |
SUPERNUS PHARMACEUTICALS | 2019-08-01 |
| 401 | A Multicenter, Double-blind, Randomized, Placebo-controlled Clinical Trial in Three Parallel Groups to Evaluate The Effectiveness and Safety of Mexidol® Film-coated Tablets, 125 Mg (LLC ‘NPK PHARMASOFT’, Russia) in The Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Children Aged 6-12 Years with Various Dosing Regimens (MEGA) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The primary objective of this study was to evaluate the efficacy and safety of Mexidol® film-coated tablets (125 mg) compared to a placebo in children aged 6 to 12 years with Attention Deficit Hyperactivity Disorder (ADHD). This multicenter, prospective, double-blind, randomized trial included 333 children who met the diagnostic criteria established by the International Classification of Diseases (ICD-10) and the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Participants received either Mexidol or placebo for 42 days, and various efficacy and safety parameters were assessed. |
POLINA S. NIKIFOROVA; | 2019-07-13 |
| 402 | The Roles of Endocrine Disrupting Chemicals, Growth Hormone and Thyroid Function in Attention-deficit/Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children and adolescents. Growth hormone and thyroid function are associated with both physical and neurocognitive development. Endocrine disrupting chemicals (EDCs) could disturb the normal function of endocrine systems, and further link to the pathophysiology of ADHD. In addition, whether methylphenidate for treating ADHD influences growth hormone and thyroid function of patients remains unclear. |
WANG LIANG-JEN; | 2019-07-12 |
| 403 | Web Based Tools to Improve Medication Continuity in Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Medication is an efficacious treatment strategy for adolescents with attention-deficit/hyperactivity disorder (ADHD), however use significantly declines during adolescence when the consequences of ADHD are most severe (e.g. dropping out of school, delinquency, … |
WILLIAM BRINKMAN; | 2019-07-02 |
| 404 | To Explore The Influence of Appetite Reduction and Medication Effect of Methylphenidate in Patients With Attention-deficit/Hyperactivity Disorder Through Pharmacogenetics PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: We plan to recruit 200 children and adolescents aged between 6 to 17 years old in two years. Those patients would receive clinical interview by child psychiatrists to diagnose as ADHD and to exclude mental retardation, major psychiatric disorders and medical disorders. Moreover, we excluded children who ever received ADHD medication treatment more than one year, or received medication in recent 30 days. Initial assessment includes collecting saliva sample, and complete questionnaires (SNAP-IV), clinical rating (CGI-S) and psychological test (CPT-II, WISC-IV, CANTAB). After 1 month methylphenidate treatment, we would evaluate SNAP-IV, CGI-S, … |
CHANG GUNG MEMORIAL HOSPITAL | 2019-07-01 |
| 405 | Transcranial Direct Current Stimulation for The Treatment of Inattention Symptoms in Attention-deficit/Hyperactivity Disorder: A Randomized, Double-blind, Parallel, Controlled Clinical Trial (TUNED Trial) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims at evaluating the efficacy and safety of a home-based tDCS device when compared to a sham stimulation for improving attention in adult ADHD patients. |
LUIS AUGUSTO ROHDE; | 2019-07-01 |
| 406 | Effectiveness of Relaxation Technique (Muscle Relaxation) for Behavioral Management of ADHD Children During Dental Treatment. (Randomized Clinical Trial) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Evaluation of effect of relaxation technique (Muscle Relaxation) on behavioral management and anxiety control of ADHD children during dental treatment. |
NOURAN KHALIFA HAMED; | 2019-07-01 |
| 407 | Transcutaneous Electrical Acupoint Stimulation for Treating Attention Deficit Hyperactivity Disorder: A Prospective, Randomized, Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: RATIONALE: Transcutaneous electrical acupoint stimulation may improve attention deficit hyperactivity disorder (ADHD). PURPOSE: This randomized-controlled trial study of treating attention deficit hyperactivity disorder of school-aged children with transcutaneous electrical acupoint stimulation to see how well it works compared to sham transcutaneous electrical acupoint stimulation. |
YAN LI; | 2019-07-01 |
| 408 | Development, Implementation, and Evaluation of An Internet-based Behavioural Sleep Intervention for Children With NDD and Insomnia PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: More than 90% of children with neurodevelopmental disorders (NDD) experience sleep problems, whereas less than 25% of typically developing children experience sleep problems. Poor sleep can have significant consequences for children’s physical and psychosocial health, as well their caregivers’ well-being. The impact of sleep problems on daytime functioning is even greater in children with NDD. Although there are a range of factors that may disturb sleep in children with NDD, the most frequent cause of sleep disturbance is behavioural insomnia. There is some evidence that behavioural interventions can be effective in improving sleep in children with NDD. However, … |
PENNY CORKUM; | 2019-06-10 |
| 409 | Stimulant Vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The study team will examine the effects of FDA approved stimulant and non-stimulant medications for ADHD, among youth with ADHD and with and without Oppositional Defiant Disorder (ODD) or Conduct Disorder (CD), on reward systems of the brain using fMRI. |
JEFFREY NEWCORN; | 2019-06-04 |
| 410 | Toll-Like Receptor Polymorphism, Antinuclear Antibodies and Beta-hemolytic Group A Streptococcus Infections in Attention-Deficit/Hyperactivity Disorder: An Observational Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this observational cross-sectional study is to evaluate the streptococcal infection (clinical history, ASLO title and anti-DNAse title B) and autoimmunity (ABGA antibodies) in a sample of 100 adult patients diagnosed with ADHD (ie in patients in whom the disorder is permanent). Another objective will be to evaluate the frequency and types of genetic alterations of innate immunity (TLR polymorphisms, MyD88, IRAK-4) that can determine an infantile susceptibility to gram positive infections (ie S. pyogenes, S. pneumoniae, S. aureus) and the possible relationship between these elements, also in relation to comorbidity with other ABGA-related pathologies, … |
FRANCESCO OLIVA; | 2019-06-03 |
| 411 | Emotional Dysregulation in Children With Attention Deficit Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Studies have shown that children with Attention Deficit Hyperactivity Disorder (ADHD) and emotional dysregulation are characterized by high severity of ADHD, comorbid behavior disorders and increased risk of chronic difficulties. New studies have shown promising results by focusing on improving emotional regulation. We lack knowledge about differences in symptom patterns, stability of symptoms over time, comorbid disorders, neurocognitive functions, knowledge and regulation of emotions, … |
PÅL ZEINER; | 2019-06-01 |
| 412 | Neural Mechanisms Underlying Attention Lapses in Adult Attention Deficit Disorder: Towards A Better Clinical Diagnosis PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: ADHD is a common disorder, leading to a significant disability that often persists in adulthood. ADHD is characterized by attentional disturbances that are difficult to asses with standard neuropsychological tests. Attention tends to stall after a certain time of fatigue (i.e. an attention lapse). The aim of this study is to study the electroencephalographic (EEG) characteristics of these attention lapses in a sustained attention task, comparing ADHD patients with healthy subjects. |
SÉBASTIEN WEIBEL; | 2019-06-01 |
| 413 | Exploratory Neuroimaging Study to Evaluate The Effect on Brain Activity of SPN-810 for Impulsive Aggression (IA) in Patients With Attention-Deficit/Hyperactivity Disorder (ADHD) in Conjunction With Standard ADHD Treatment PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effect of 4-week SPN-810 treatment on brain functioning in patients aged 8-12 years with ADHD and associated feature of impulsive aggression (IA). This will be achieved using functional magnetic resonance imaging (fMRI) in conjunction with the point subtraction aggression paradigm (PSAP) Task, a behavioral aggression paradigm in which subjects are provoked by having money indirectly taken from them by a fictitious opponent, simulating an aggression response. |
SUPERNUS PHARMACEUTICALS | 2019-05-30 |
| 414 | The Feasibility of A Microbiome Dietary Intervention in Children With ADHD Related Papers Related Patents Related Grants Related Experts View Highlight: The aim is to conduct a feasibility pilot study of a dietary intervention designed to optimise gut bacteria in children diagnosed with ADHD. |
ST MARY’S UNIVERSITY COLLEGE | 2019-05-14 |
| 415 | A Study to Assess Midline Frontal Theta (MFT) Power As Measured By Stimulus-locked Electroencephalography (EEG) Before and After AKL-T01 Treatment for Improving Attention in Pediatric Participants Ages 8-12 Years Old With Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a single arm, open-label, pilot study to assess midline frontal theta (MFT) power as measured by stimulus-locked electroencephalogram (EEG) before and after treatment with AKL-T01 for improving attention in pediatric participants ages 8-12 years old with attention deficit hyperactivity disorder (ADHD). |
ELYSA J MARCO; | 2019-05-10 |
| 416 | Effectiveness of Methylphenidate Late Formula to Reduce Cannabis Use in Young Cannabis-Related Patients and Attention Deficit Disorder Hyperactivity Related Papers Related Patents Related Grants Related Experts View Highlight: Abuse of psychoactive substances is a behavior belonging to the field of risk behaviors that begins and takes place during adolescence. These risk behaviors are a major public health problem in France and worldwide. Cannabis is the first illicit drug consumed by adolescents in France. His experimentation progresses rapidly between 11 and 17 years. The relationship between cannabis use and mental health has been shown by several studies. In particular Attention Deficit Hyperactivity Disorder (ADHD), characterized by attention deficit, impulsivity and disabling motor hyperactivity and beginning before 12 years of age (DSM-5), … |
PEYRET EMMANUELLE; | 2019-05-07 |
| 417 | Targeting Child Mental Health and Household Poverty PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Living in poverty has long-lasting negative effects on children’s mental health and on their mental health in adulthood. Child poverty is very common, affecting 17% of Canadian children. Many low income families may not be getting all the social benefits they are entitled to receive. Increasingly, there are calls for primary care providers to ask all patients about poverty and to intervene if poverty is identified. However, … |
IMAAN BAYOUMI; | 2019-05-01 |
| 418 | The Early Life Clinical Feature and Risk Factors Analysis Using Artificial Intelligence in Children With Neurodevelopmental Disorders: Premature Infants Cohort Study PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: The study will be a 5-year retrospective and prospective case control study, included 650 participants, and participants will be divided into four groups.By this research the investigators will achieve several aims:(1) Through the cross-sectional analysis of this study, the investigators can understand the current prevalence of developmental disorders in Taiwan ,especially ADHD and ASD, and the ratio of male to female in school-age children. (2) Analysis of risk factors in preterm infants during pregnancy and infant, and construct the diagnostic predictive models. (3) By the cohort study of premature infants, … |
CHANG GUNG MEMORIAL HOSPITAL | 2019-04-29 |
| 419 | Sleep Patterns in Children and Adolescents With ADHD: Impact on Cognitive Functions and Quality of Life PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is aimed to find out Sleep profile differences in children and adolescents with and without ADHD,Relationship between sleep profile disturbance and ADHD symptoms, Impact of sleep disturbance on cognition functions and quality of life. |
MUSTAFA M. HASHEM; | 2019-04-23 |
| 420 | A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Other psychiatric disorders, including anxiety, often co-occur with adult ADHD; with 85% of ADHD patients having at least one other psychiatric condition. The presence of a co-occurring anxiety disorder has been associated with additive clinical effects, leading to more global impairment, poorer outcome, greater resistance to treatment and increased costs of illness. Stimulants are effective first-line treatments for adult ADHD patients, however the literature has mostly examined these treatments in pure ADHD populations (i.e. without other psychiatric disorders). Thus, … |
MICHAEL VAN AMERINGEN; | 2019-04-20 |
| 421 | A Study on The Metabolic Pathway of Tryptophan and Executive Dysfunction in Children With Attention Deficit Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The present project is to identify the relationship between ADHD and the metabolites of tryptophan. |
CHI-YUNG SHANG; | 2019-04-01 |
| 422 | Network Control and Functional Context: Mechanisms for TMS Response PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study uses different types of functional magnetic resonance imagining (fMRI) to generate individual transcranial magnetic stimulation (TMS) targets. During the TMS/fMRI imagining sessions, the investigators stimulate a target of either high or low regional controllability during a working memory task to investigate network responses and the impact of TMS on behavior. |
UNIVERSITY OF PENNSYLVANIA | 2019-03-25 |
| 423 | A Randomized Placebo-controlled Trial of ARBaclofen Vs. Placebo in The Treatment of Children and Adolescents With ASD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will examine the safety and efficacy of arbaclofen vs. placebo on social function in children and adolescents with Autism Spectrum Disorder (ASD). |
EVDOKIA ANAGNOSTOU; | 2019-03-18 |
| 424 | Attentional and Emotional Processing of Complex Visual Scenes in Children With Attention Deficit Disorder With or Without Hyperactivity PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The aim of this study is to analyse explicit and implicit emotional information processing abilities in children with attention deficit disorder with or without hyperactivity |
FOSSOUD CATHERINE; | 2019-03-15 |
| 425 | Recollect The Game: A Novel Treatment for Executive Functioning Deficits in Adults With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Adults who have attention deficit hyperactivity disorder (ADHD) suffer from significant occupational, academic and social problems, many of which are believed to be a result of problems with executive functioning. Executive functioning refers to a group of neuro-psychological functions which include sustained attention, working memory, verbal fluency, as well as motor and mental processing speed. Individuals with ADHD have been shown to have deficits in executive functioning independent of IQ, co-occurring psychiatric disorders, gender, … |
MICHAEL VAN AMERINGEN; | 2019-03-14 |
| 426 | Mindfulness-Based Behavioural Group Therapy for Adult Attention Deficit Hyperactivity Disorder – Randomized Clinical Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The study is developed to validate a new short psychotherapeutic group treatment for adults with ADHD diagnosis. The participants will be treated in a monocentric, parallel group randomized superiority study – one group with the new treatment and one group with well established relaxing treatment. |
PETER TONN; | 2019-03-01 |
| 427 | A Mixed Methods Evaluation Study of Brief Mindfulness-based Stress Reduction and Brief Related Papers Related Patents Related Grants Related Experts View Highlight: Mental health issues are increasingly costly in Quebec. Given most psychological disorders occur before age 24, university-based interventions are appealing to prevent and treat mental illness, especially as rates of psychological distress have peaked among university students in our province. This at-risk population may benefit from new university-based programs, as academic institutions now face limited staffing and an increasing number of students seeking services. Mindfulness-based Stress Reduction (MBSR) programs are a promising approach, reporting substantial increases in emotional regulation. Novel mindful self-compassion (MSC) programs additionally display increasing improvements in resilience, … |
SOHAM REJ; | 2019-03-01 |
| 428 | Assessment of Pharmacogenomics Testing for Improving Pediatric ADHD Psychopharmacological Treatment: A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This research study is a randomized controlled trial (RCT) to test whether pharmacogenomics (PGx) testing for ADHD medications will help guide clinicians to choose medications and dosages for pediatric ADHD treatment that provide faster symptom relief, fewer or less severe side effects, improve patient quality of life, and lessen emotional stress for parents/guardians of the patients. |
DAN HANDLEY; | 2019-02-28 |
| 429 | Randomized Placebo-controlled Treatment of Impulsivity in Adults With Probiotics PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: A multicentre randomized double-blind placebo controlled parallel design (10 weeks) study investigating probiotic supplementation in highly impulsive adults (18-65 yrs; N=180). The probiotic studied is Synbiotic2000Forte that contain three well-studied anti-inflammatory lactic acid bacteria (LABs) and four fermentable fibers: Pediococcus pentosaceus 5-33:3, Lactobacillus paracasei subsp paracasei 19, and Lactobacillus plantarum 2362 in combination with the following four fermentable fibres: betaglucan, inulin, pectin and resistant starch. With this study we aim to detect, whether treatment with probiotics is effective in adults with high levels of impulsivity, compulsivity, and aggression. |
JOSEP ANTONI RAMOS-QUIROGA; | 2019-02-22 |
| 430 | Integrating Brain Imaging and Rehabilitation to Improve Outcomes for Children With Co-occurring DCD & ASD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that affects a child’s ability to learn motor skills, such as tying shoelaces, learning to print, or riding a bicycle (APA 2013). It often co-occurs with other conditions, such as Attention Deficit Hyperactivity Disorder (ADHD). Its high co-occurrence with Autism Spectrum Disorder (ASD) has only been permitted since 2013 so it is less well known. Recent neuroimaging studies have begun to unravel the neural underpinnings of each disorder; however, … |
JILL ZWICKER; | 2019-02-20 |
| 431 | Impact of Relationship of Epilepsy and Attention Deficit Hyperactive Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The most common neuropsychiatric disorder in early childhood is attention deficit/hyperactivity disorder (ADHD) with evidence of abnormality in structure and function of brain. Epilepsy is one of the commonest comorbidity associated with ADHD with negative outcome on childrens’ quality of life, and is considered to be a risk for academic underachievement. These two disorders are highly associated, with more possibility to be a bidirectional relationship. The mechanisms of this comorbidity are unknown. In this association, … |
GELLAN KARAMALLLAH RAMADAN AHMED; | 2019-02-15 |
| 432 | An Open-label, 52-Week, Multicenter Trial Evaluating The Long-term Safety and Tolerability of Centanafadine Sustained-Release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the long-term safety and tolerability of centanafadine sustained-release tablets, administered twice daily in the treatment of adults with attention deficit hyperactivity disorder (ADHD). |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2019-02-14 |
| 433 | The Effects of Chiropractic Care on Behavior, Neurological Function and Quality of Life in Children With Attention Deficit Hyperactivity Disorder: A Randomized Controlled Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To date the effects of chiropractic care on behavior and neurological function in children diagnosed with ADHD has not been investigated thoroughly and is limited mostly to case studies and retrospective case reviews. Our research group recently completed a pilot study that investigated the effects of a single session of chiropractic care on oculomotor function and reading ability in children with ADHD. The findings of this study suggested that chiropractic care may have a role in improving oculomotor control and reading ability in this population group. This proposed study is the next step in this program of research and is a pilot clinical trial that will investigate whether 4 weeks of chiropractic care influences behavior, neurological function, or quality of life in children with ADHD. |
IMRAN AMJAD; | 2019-02-02 |
| 434 | Assessment of Stability of Behavioral and Neural Measures of Attention Networks Across Multiple Sessions PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this research study is to learn more about the stability over multiple recording sessions of brainwave activity during a computerized task that measures different types of attention. |
WILLIAM PERLSTEIN; | 2019-01-31 |
| 435 | SPARCLAR: A Feasibility Randomised Controlled Trial of A Parenting Support Programme Focussed on Families Affected By ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-Deficit/Hyperactivity Disorder (ADHD) is a chronic and pervasive disorder characterised by problems in attention, impulse control and activity regulation that substantially burdens patients, families, and society. The efficacy of behavioural training for parents of children with ADHD symptoms is well established, however it is less clear which type of parenting intervention should be offered, … |
LUCY THOMPSON; | 2019-01-21 |
| 436 | A Phase 3, Randomized, Double-blind, Multicenter, Placebo-controlled, Parallel-group Trial Evaluating The Efficacy, Safety, and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This study evaluates the efficacy, safety, and tolerability of centanafadine sustained-release tablets in adults with attention-deficit/hyperactivity disorder (ADHD). Participants will either receive a twice-daily dose of centanafadine sustained-release tablets, or twice-daily placebo. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2019-01-16 |
| 437 | A Phase 3, Randomized, Double-blind, Multicenter, Placebo-controlled, Parallel-group Trial Evaluating The Efficacy, Safety, and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This study evaluated the efficacy, safety, and tolerability of centanafadine sustained-release tablets in adults with ADHD. Participants either received a twice-daily dose of centanafadine sustained-release tablets, or twice-daily placebo. |
OTSUKA PHARMACEUTICAL DEVELOPMENT & COMMERCIALIZATION | 2019-01-16 |
| 438 | Near-infrared Spectroscopy Neurofeedback As A Treatment for Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To observe the clinical efficacy and mechanism of functional near-infrared spectroscopy imaging neurofeedback therapy for attention deficit and hyperactivity disorder. |
WU WENJUN-1; | 2019-01-15 |
| 439 | Repetitive Transcranial Magnetic Stimulation and Cognitive Training for Treatment of Cognitive Problems in Adults With Schizophrenia: A Pilot Randomized Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The proposed project aims to establish the feasibility and tolerability of delivering repetitive transcranial magnetic stimulant (rTMS) combined with computerized cognitive training in patients with Schizophrenia or Schizoaffective Disorder and cognitive difficulties. The investigators will conduct a 2 week randomized controlled trial study evaluating computerized cognitive training combined with either active or sham rTMS on cognitive and functional outcomes in adults with Schizophrenia or Schizoaffective Disorder. |
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE | 2019-01-15 |
| 440 | Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 Related Papers Related Patents Related Grants Related Experts View Highlight: Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present there is no specific treatment for this NF1 complication. However, data from rodent models of NF1 along with uncontrolled clinical observations in children with NF1 suggest that the anti-oxidant, glutamate modulating compound N-Acetyl Cysteine (NAC) may reduce these impairments. Of particular interest is a murine study analyzing the central nervous system manifestations of NF1 at our institution. That study revealed a role for myelin-forming oligodendrocytes in the control of nitric oxide synthases (NOS) and their product, nitric oxide, … |
DONALD L GILBERT; | 2019-01-15 |
| 441 | Enhancing IEPs of Children With ADHD Using Daily Report Cards: An Efficacy Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study are to determine the effectiveness of the daily report card (DRC) approach to supporting children with ADHD in special education in schools compared to a business as usual condition. Children in the study will be randomly assigned to business as usual, or to receive a DRC based on Individualized Education Program goals and objectives, across the school year. All children will have progress carefully monitored across the school year. |
GREGORY FABIANO; | 2019-01-03 |
| 442 | Monocentric Study on The Quality of Life Among Adolescents With Attention Deficit/Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention Deficit Hyperactivity Disorder (ADHD) with a overall prevalence of 5.3% is one of the most common neurobehavioral disorders in children. In the foreign literature, many studies bring to light in children and adolescents the negative impact of ADHD on overall quality of life. Some of these studies were able to identify the fact that the higher the age of ADHD children or adolescents, the lower the quality of life. Currently, to our knowledge, only a few European studies have demonstrated the negative impact of ADHD on the quality of life of children and adolescents. In addition, … |
VANESSA WOLFF; | 2019-01-02 |
| 443 | Analysis of Ocular and Neurodevelopmental Function in Patients With History of Retinopathy of Prematurity and Prior Treatments: 3 to 12 Years Outcome PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this research project is to identify the long-term outcome of neurodevelopment in patients with retinopathy of prematurity(ROP) and the treatment of anti-vascular endothelial growth factor (VEGF) such as intravitreal injection of bevacizumab (IVB), ranibizumab, or aflibercept.Investigators propose this study hopefully to have a better understanding of the long-term safety of anti-VEGF on the treatment of ROP. Studies in both animalsand humans have found evidence of systemic bevacizumab exposure after IVB. In an animal study, … |
WU WEI-CHI; | 2019-01-01 |
| 444 | Prevalence of New Psychoactive Substances Use Among Outpatient of Addiction Management Clinic in Assiut University Hospital PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: According to the United Nations Office on Drugs and Crime [UNODC] World Drug Report, the annual prevalence of drug use seemed to be stable for the past few years. However, new psychoactive substances (NPS) have increased drastically in both supply and demand.Many NPS were discovered at the same time as other drugs, and it was simply, for whatever reasons, these other drugs became popular. The majority of these substances are chemicals produced by tweaking or altering the molecular structure of previous well-known psychoactive agents such as cannabis, cocaine, methylenedioxymeth-amphetamine (or MDMA, commonly known as ecstasy), … |
ROMANY H GABRAH; | 2019-01-01 |
| 445 | Comparison of Effects Between SMR/Delta Ratio and Beta1/Theta Ratio Neurofeedback Trainings for Older Adults With Mild Cognitive Impairment: A Protocol for A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a non-pharmacological study evaluating the effects of SMR/delta ratio and beta1/theta ratio neurofeedback trainings on cognitive performance and electrical brain activity in elderly with mild cognitive impairment. |
FABIENNE MARLATS; | 2019-01-01 |
| 446 | High Incidence of Adult Respiratory Distress Syndrome Associated With Amphetamine Use in The Burn Population PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Methamphetamine and amphetamine has various cardiovascular and central nervous system effects. Long-term use is associated with many adverse health effects including cardiomyopathy, hemorrhagic, and ischemic stroke. Death is usually caused by cardiovascular collapse and while amphetamine abuse has been considered as a potential cause of acute respiratory distress syndrome, the reports are usually anecdotal. This investigation considers reviewing individuals with few to zero medical conditions who develop acute respiratory distress syndrome and are methamphetamine positive |
DAVID T WONG; | 2019-01-01 |
| 447 | Melatonin in Youth: N-of-1 Trials in A Stimulant-treated Attention Deficit Hyperactivity Disorder (ADHD) Population Related Papers Related Patents Related Grants Related Experts View Highlight: This study is a multi-center, randomized, triple-blind, placebo-controlled parallel-group trial, in which each participant is offered an N-of-1 trial. The purpose of this study is to assess the efficacy and safety of melatonin (3 mg or 6 mg) compared with placebo for initial insomnia in children with attention-deficit disorder. |
SUNITA VOHRA; | 2019-01-01 |
| 448 | Software Treatment for Actively Reducing Severity of ADHD As Adjunctive Treatment to Stimulant (STARS-ADHD Adjunctive) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to determine the effects of combining AKL-T01 (with AKL-X01 symptom tracking) as adjunctive treatment to stimulant medication, and to understand the effects of AKL-T01 treatment (with AKL-X01 symptom tracking) in participants not recently on medication. |
DANIEL LAZKOWITZ; | 2018-12-28 |
| 449 | Impact of Combined Medication and Behavioral Treatment in Young Children With Comorbid ASD and ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Children with comorbid autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) have significantly worse outcomes than those with either ASD alone or ADHD alone. Effective early treatments that account for ADHD symptoms have not been developed for young children with ASD+ADHD. The overarching goals of this randomized, placebo-controlled, phase 2, pilot study are to (1) evaluate a novel early intervention that pharmacologically addresses ADHD symptoms while providing an ASD-targeted behavioral intervention, … |
GERALDINE DAWSON; | 2018-12-14 |
| 450 | Effects of Short Daytime Nap on Neurocognitive Functioning and Behavior in Chinese Primary School Children PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: Previous studies showed that insufficient sleep has a negative impact on children’s physical and psychological health. Napping was found to decrease sleepiness and improve daytime functioning in adults and adolescents. The effects of napping on children, however, is unknown. The current study aims to test the effects of short daytime classroom naps on daytime functioning and behaviour in elementary school children. |
SHIRLEY XIN LI; | 2018-12-01 |
| 451 | Dog Assisted Therapy Program for Children With Attention Deficit Hyperactivity Disorder: A Randomized Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study was to evaluate the efficacy of AAT intervention in children with Attention Deficit Hyperactivity Disorder (ADHD), in terms of improving functionality, ADHD-associated symptoms, attention and working memory. Participants were recruited from a community Child and Adolescent Mental Health Service and a Primary Health Care Center. These objectives were accomplished through a multicenter, randomized clinical trial, open-label, two-arm study of AAT for children with ADHD. |
M. DOLORES RODRIGO CLAVEROL; | 2018-12-01 |
| 452 | Drug Utilisation Study of Intuniv® (Guanfacine Extended Release) in European Countries PF:7 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate and characterize people who are taking Intuniv, analyze prescribing behaviors of physicians, and determine whether Intuniv was correctly prescribed in Belgium, Denmark, Finland, Germany, Ireland, Netherlands, Norway, Spain, Sweden, and the United Kingdom. |
SHIRE | 2018-11-15 |
| 453 | Evaluation of The Feasibility of Family Strength-oriented Therapy Conversation for Families of 13-18 Years Old Adolescents With Attention-Deficit/Hyperactivity Disorder, at The Child and Adolescent Outpatient Unit: A Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD), is a highly genetic and complex neurological disorder, where disruptive behavior, emotional imbalance, and lack of attention can interrupt with normal development of adolescents, self-awareness, and self-regulation in a way that has an impact on the family unit. Effective family intervention programs, that empower resilience and strength, to cope with the stressful situation from ADHD, are therefore needed. Nevertheless, there is a lack of knowledge regarding what type of interventions are the most effective for these families. As well as, … |
ERLA KOLBRÚN SVAVARSDÓTTIR; | 2018-11-13 |
| 454 | A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Study Investigating The Efficacy, Safety, and Tolerability of JNJ-42165279 in Adolescent and Adult Subjects With Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the efficacy of JNJ-42165279 compared with placebo in the improvement of symptoms of Autism Spectrum Disorder (ASD) during 12 weeks of treatment using the Autism Behavior Inventory (ABI). |
JANSSEN RESEARCH & DEVELOPMENT | 2018-11-07 |
| 455 | A Phase 4, Double-blind, Randomized, Parallel Group, Placebo-controlled Study Of The Efficacy And Safety Of Quillichew (Methylphenidate Hydrochloride (Hcl)) Extended Release Chewable Tablets (Erct) In 4-5 Year Old Children With Attention Deficit Hyperactivity Disorder (Adhd) Related Papers Related Patents Related Grants Related Experts View Highlight: A 6-week double-blind study to evaluate the safety and efficacy of Quillichew extended release chewable tablets in 4-5 year old children with attention deficit hyperactivity disorder. |
PFIZER | 2018-10-31 |
| 456 | Cognitive Behavioral Therapy for University Students Diagnosed With Attention-deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Drug treatment is often the first and only line of treatment available for ADHD. However, some do not benefit from medication. The importance of psychotherapy is becoming more widely accepted. In this study a group of university students diagnosed with ADHD will be offered cognitive behaviour therapy (CBT) in groups. The treatment will be provided by a Clinical Nurse Specialist in psychiatric nursing (CNS), in cooperation with school counsellors at the University of Iceland and the Reykjavík University. Brief CBT treatment will be offered, i.e. six group sessions, … |
UNIVERSITY OF ICELAND | 2018-10-11 |
| 457 | Acute Effects of Exercise in College Students With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The overall objective of this study is to examine physical exercise as an intervention for ADHD. The rationale for the proposed study is that physical exercise could serve as an effective treatment for college students with ADHD that has low costs, low risks, and ancillary health benefits and may address the limitations of existing treatments. The central hypothesis is that college students with ADHD will exhibit greater degrees of improvement in executive functioning (i.e., sustained attention, working memory) immediately following sprint interval training (SIT), … |
CYNTHIA M HARTUNG; | 2018-10-08 |
| 458 | Motor Proficiency in School Age ADHD: Contribution of Different Comorbidities PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: In this study, aged 6-10 years, male, right hand dominant, diagnosed with ADHD, accepting to take part in the study and applying to the Child and Adolescent Psychiatry Department between October 1, 2018 – October 1, 2019 were included in the research group.As for the control group, … |
NILAY ŞAHAN; | 2018-10-01 |
| 459 | Experimental FMRI Study on The Comparison of The Brain Function Effects of A Single Dose of Guanfacine and Lisdexamfetamine Relative to Placebo in Children and Adolescents With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is not a clinical trial. The aim of this study is to understand the mechanism of action of two recently licensed drugs for ADHD on brain function. We will compare the brain activation changes elicited by Guanfacine extended release (GXR; a non-stimulant drug) with the brain activation changes elicited by Lisdexamfetamine (LISDEX; a stimulant drug) and by placebo in 20 drug-free patients with ADHD using functional Magnetic Resonance Imaging (fMRI). For this purpose we intend to scan participants during their performance of tasks of attention, working memory, and inhibition, … |
KATYA RUBIA; | 2018-10-01 |
| 460 | TDCS and Motor Learning in Children With DCD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Children with a neurodevelopmental condition called developmental coordination disorder (DCD) struggle to learn motor skills and perform daily activities, such as tying shoelaces, printing, riding a bicycle, or playing sports. Evidence suggests that motor-based interventions combined with non-invasive brain stimulation to the motor cortex (transcranial direct-current stimulation, tDCS) has been effective in improving motor skills in children with cerebral palsy and other neurodevelopmental disorders, but few studies have examined tDCS in chidlren with DCD. The purpose of this randomized, blinded, … |
JILL ZWICKER; | 2018-09-27 |
| 461 | A Multi-Center, Open Label, Evaluation of The Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effect and safety of Lisdexamfetamine dimesylate (Vyvanse®) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents with ADHD and comorbid Autism Spectrum Disorder (ASD). This would be a novel study as there is no known safety or efficacy data for amphetamine based medications in this population. In addition, although health related quality of life and executive function are known to improve with the treatment of lisdexamfetamine dimesylate in the ADHD population (Banaschewski 2013; Findling 2009; Turgay 2010), … |
JUDY VAN STRALEN; | 2018-09-26 |
| 462 | A Phase 4, Open-label, Safety, Tolerability And Pharmacokinetic Study Of Methylphenidate Hydrochloride (Hcl) Extended Release Chewable Tablet (Erct) In 4-5 Year Old Children With Attention Deficit Hyperactivity Disorder (Adhd) Related Papers Related Patents Related Grants Related Experts View Highlight: 2-week open-label safety, tolerability and pharmacokinetic study of methylphenidate HCl ERCT in 4-5 year old children with ADHD. |
PFIZER | 2018-09-25 |
| 463 | A Randomized, Sham-Controlled, Crossover Study to Evaluate The Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in Children and Adolescents Diagnosed With Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate performance on the Attention Deficit Hyperactivity Disorder ( ADHD) Battery of the Cambridge Automated Neuropsychological Test Battery (CANTAB), including spatial working memory, inhibitory control, and attention while using either a noise cancelling headphone or sham headphone control in the presence of standardized auditory distractors in children and adolescents with ADHD. |
DUKE UNIVERSITY | 2018-09-21 |
| 464 | Validation of A Collaboration Evaluation Form for The Purposes of Dental and Orthodontic Treatment of The Patient With Down Syndrome PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Since subjects with Down Syndrome (DS) have different and variable levels of intellectual deficit, in approaching the patient with DS and before evaluating the different therapeutic strategies and carrying out a dental and orthodontic treatment, … |
FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS | 2018-09-20 |
| 465 | A Phase 4, Double-blind, Randomized, Parallel Group, Placebo-controlled Study Of The Efficacy And Safety Of Methylphenidate Hydrochloride (Hcl) Extended Release Chewable Tablet (Erct) In 4-5 Year Old Children With Attention Deficit Hyperactivity Disorder (Adhd) Related Papers Related Patents Related Grants Related Experts View Highlight: This 6-week study is to determine if the study drug, Methylphenidate Hydrochloride (HCl) Extended-Release Chewable Tablets (ERCT), is safe, tolerable and effective when compared to a sugar pill or placebo in children 4 to 5 years of age with ADHD. |
PFIZER | 2018-09-19 |
| 466 | Enhanced Support for Behavioral Barriers to Learning: An Evaluation of The SCHOOL STARS (Supporting Child Health Outcomes, Optimizing Learning, Striving to Achieve Real Solutions) Program PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This small pilot study will enroll children ages 5-12 years of age with disruptive behavior problems at school. These children and their families will be offered an enhanced model of primary care, which includes pre-visit record review, standardized content of primary care visits, post-visit care coordination by the primary care team, and coordination of services between the primary care team and the school. We hypothesize that children receiving this enhanced model of care will achieve better behavioral outcomes at both school and home. |
COURTNEY M BROWN; | 2018-09-14 |
| 467 | A Multicenter, Fixed-Dose, Double-Blind, Randomized Study to Evaluate The Efficacy and Safety of AR19 (Amphetamine Sulfate) in Adult Subjects (Ages 18-55) With Attention Deficit Hyperactivity Disorder (ADHD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of the AR19.004 study is to assess the efficacy of AR19 compared to placebo using the Adult ADHD Investigator Symptom Rating Scale (AISRS) |
ARBOR PHARMACEUTICALS | 2018-09-13 |
| 468 | Premature Children-executive Functions and Training With Cognitive Motion-based Videogames (Intendu®): A Rehabilitation Project PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: in more than 60% of premature children processing speed and academic failures are observed, even in children with a normal cognitive level. The aim of the study is to use for rehabilitation an application for training functional cognitive skills (Intendu®). It is a software which is able to interact with the patient through a video monitoring feedback (Kinect®), enhancing brain plasticity of patients with brain dysfunction. |
BARBARA SCELSA; | 2018-09-11 |
| 469 | The Effect of Bibliotherapy on Parent and Child Knowledge of ADHD and Treatment Follow-up PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood. It affects approximately 8% of school aged children and is characterized by persistent symptoms of inattention and/or hyperactivity/impulsivity. Typical ADHD assessments primarily involve interviewing the parents and gathering rating scales from parents and teachers. Feedback regarding diagnosis, clinical conceptualization, and treatment recommendations is usually provided by the clinical staff to the child’s parents in the absence of the child. Hence, … |
CHILDREN’S HOSPITAL MEDICAL CENTER CINCINNATI | 2018-08-20 |
| 470 | A Multicenter, 2-Part, 6-Week, Double-blind, Randomized, Placebo-controlled, Parallel-design Study to Assess The Efficacy and Safety of AEVI-001 in Children and Adolescents (Ages 6-17 Years) With Attention Deficit Hyperactivity Disorder and With or Without Copy Number Variants in Specific Genes Implicated in Glutamatergic Signaling and Neuronal Connectivity PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This is PART B of a 2-part, 6-week, double-blind, dose-optimization, parallel-group study in children and adolescents (ages 6-17 years) with ADHD with and without CNVs in specific genes implicated in glutamatergic signaling and neuronal activity. PART B will assess subjects who do not have CNVs in any of the specific gene mutation(s) implicated in glutamatergic signaling and neuronal connectivity. |
AEVI GENOMIC MEDICINE LLC A CERECOR COMPANY | 2018-08-17 |
| 471 | Neurophysiological Marker of Attention Deficit Hyperactivity Disorder in Children PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study investigated quantitative electroencephalography (QEEG) subtypes as auxiliary tools to assess Attention Deficit Hyperactivity Disorder (ADHD). Patient assessed using the Korean version of the Diagnostic Interview Schedule for Children Version IV and were assigned to one of three groups: ADHD, ADHD-Not Otherwise specified (NOS), and Neurotypical (NT). The investigators measure absolute and relative EEG power in 19 channels and conducted an auditory continuous performance test. The investigators analyzed QEEG according to the frequency range: delta (1-4 Hz), theta (4-8 Hz), slow alpha (8-10 Hz), fast alpha (10-13.5 Hz), … |
JUNWON KIM; | 2018-08-08 |
| 472 | School-Based Depression Prevention for Adolescents With ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to develop a modified behavioral activation program in adolescents with ADHD to be implemented by school mental health providers in an urban, low-income school district. Subsequently we will examine its effectiveness in reducing depressive symptoms and improving emotion regulation and reward responsivity, compared to usual care. |
MICHAEL MEINZER; | 2018-08-07 |
| 473 | Pilot Study: Addressing Home-Based Functional Challenges Via Telehealth-Based Occupational Therapy PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to measure the impact of a telehealth-based model of occupational therapy (OT) treatment on clinical outcomes for children with autism spectrum disorder (ASD) and/or attention deficit hyperactivity disorder (ADHD). Half of the participants will receive clinic-based, in-person services and half of the participants will receive video-based, Telehealth services. |
KAREN HARPSTER; | 2018-08-06 |
| 474 | Open-Label Placebo Treatment of Women With Premenstrual Syndrome: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to investigate the effect of an open-label placebo intervention on premenstrual syndrome (PMS) complaints. Women who suffer from moderate to severe PMS will be randomly allocated to three groups: to a treatment as usual group, an open-label placebo group, and an integrative open-label placebo group. Participants of all groups will conclude a prospective PMS screening for one menstrual cycle. Thereafter, … |
JENS GAAB; | 2018-08-02 |
| 475 | Studies of Brain and Body Interaction at Rutgers University PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this study is to characterize biophysiolgoical signals as a comprehensive profile of the nervous systems in order to understand interactions between the brain and body, while an individual performs naturalistic behaviors (ex. walking, pointing) and while breathing at a slow controlled pace. The investigators aim to study these interactions among a variety of populations, from healthy individuals to those with disorders such as Autism Spectrum Disorder(s), including those who may also have an ADHD (Attention-deficit/hyperactivity disorder) diagnosis, Asperger’s Syndrome, Alzheimer’s Disease, and/or Fragile X syndrome |
ELIZABETH B TORRES; | 2018-08-01 |
| 476 | Treatment Effects of Cognitive Training on Children With Attention Deficit Hyperactivity Disorder and Developmental Delay PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Using a single blind, randomized controlled design to study the additional therapeutic effects of cognitive training on traditional rehabilitation programs for children with attention deficit hyperactivity disorder and developmental delays. |
RU-LAN HSIEH; | 2018-08-01 |
| 477 | The Antidepressant Advisor: A Decision Support System for UK Primary Care – A Feasibility Study: Study 3 PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This prospective observational study (ADeSS-Study3) investigates candidate biomarkers prospectively predicting response to antidepressant medications and prognosis in major depressive disorder (MDD). Currently, about half of MDD patients will not respond to the first course of selective serotonin reuptake inhibitors (SSRIs), while more than 40% will also not achieve remission after a second round of another SSRI. There are functional magnetic resonance imaging (fMRI) measures in several brain regions, … |
ROLAND ZAHN; | 2018-08-01 |
| 478 | Assessment of Efficacy and Safety of SPN-810 for The Treatment of Impulsive Aggression (IA) in Adolescent Subjects With Attention Deficit/Hyperactivity Disorder (ADHD) in Conjunction With Standard ADHD Treatment PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to evaluate the effect of SPN-810 for the treatment of impulsive aggression (IA) in adolescents diagnosed with ADHD when taken in conjunction with standard ADHD treatment. |
SUPERNUS PHARMACEUTICALS | 2018-07-31 |
| 479 | A Study of Identity Building in Children With Attention Deficit Hyperactivity Disorder (ADHD) PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Context: Attention Deficit Hyperactivity Disorder (ADHD), a major public health issue, is a neurodevelopmental disorder characterized by disturbance of attention, pathological impulsivity and a variable level of psychomotor hyperactivity. In addition to medium-term repercussions such as school failure or family dysfunction, these children have difficulties in dealing with emotions, … |
MARIE-AMÉLIE TORDJMAN-MADIGAND; | 2018-07-20 |
| 480 | Single-dose Potassium Supplementation in ADHD Patients With Lidocaine Ineffectiveness PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Randomized, controlled, double-blind trial of the effect of a single dose of potassium on ADHD symptoms as measured by changes in measures of symptoms of ADHD correlated with the results of their Lidocaine Effectiveness Test. |
MICHAEL M SEGAL; | 2018-07-01 |
| 481 | The Prevalence and Predictors of Gastrointestinal Symptoms in Children With Attention Deficit / Hyperactivity Disorder PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is to examine the gut problems in children with attention deficit hyperactivity disorders (ADHD) and is conducted by the Department of Psychiatry of Alice Ho Miu Ling Nethersole Hospital. Children with ADHD who attend our department will be recruited with their parents/guardians’ consent. Only the primary caregiver will be invited for an interview to assess the recruited children’s gut problems, autistic features, emotional problems, … |
NG SIU FUNG JONATHAN; | 2018-07-01 |
| 482 | Attention Deficit Hyperactivity Disorder (ADHD) Prediction of Treatment Response PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a 6-month trial in adults to find out if certain neuromarkers can predict individual treatment response to stimulant medications for Attention Deficit Hyperactivity Disorder (ADHD). Males and females, ages 18-45, will complete an MRI scan at MIT prior to beginning medication for ADHD as determined by a treating clinician outside the context of this study. |
JOSEPH BIEDERMAN; | 2018-07-01 |
| 483 | Correlation Between Balance and Attention in Children With Attention Deficit Hyperactivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Objective: The present study aimed to determine balance in children with attention deficit hyperactivity disorder compared to normal peers. Also, it investigated the correlation between their balance and the total percentile scores of ADHD Rating Scale-IV. Design: Cross sectional design. Methods: Sixty children participated in this study from both sexes (42 boys and 18 girls) with age ranged from 60 to 84 months. They were divided into two groups based on the ADHD Rating Scale-IV. Control group: 30 typically developed children from both sexes (20 boys and 10 girls) with mean age 67.53 ± 1.41 months. They had the total percentile scores of ADHD Rating Scale-IV ≤ 50. Study group: 30 children from both sexes (22 boys and 8 girls) suffering from attention deficit hyperactivity disorder (ADHD) with mean age 68.60 ± 4.62 months. They had the total percentile scores of ADHD Rating Scale-IV ≥ 93. Both groups were assessed for their balance by Pediatric Balance Scale (PBS). |
AMIRA HUSSIN HUSSIN MOHAMMED; | 2018-07-01 |
| 484 | Network Analysis of Co-morbid Symptoms of Adult Major Depressive Disorder and Attention-deficit Hyperactivity Disorder in An Outpatient Population PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: The study is an investigation to determine co-morbid symptoms between adult major depressive disorder (MDD) and adult attention-deficit hyperactivity disorder (ADHD) using a novel statistical technique called network analysis. |
HEALTH SCIENCES NORTH RESEARCH INSTITUTE | 2018-06-21 |
| 485 | Electroclinical Effect of Steroid in Patients With Benign Childhood Epilepsy With Centrotemporal Spikes PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Benign epilepsy with centro-temporal spikes is the most common type of focal epilepsy in children. It is known to be age-dependent and presumably genetic. Age of onset ranges from one to fourteen years and it represents fifteen percent to twenty five percent of epilepsy in children under 15 years of age. |
KHALAF A SAYED; | 2018-06-20 |
| 486 | The Multi-site Study of The Early Integrated Intervention for Child Brain-developmental Disorders in China PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is focused on developing the early integrated intervention for child brain-developmental disorders, including globe developmental delay (GDD), autism spectrum disorder (ASD), and attention deficit-hyperactivity disorder (ADHD), in China. |
XIU XU; | 2018-06-15 |
| 487 | Efficacy of Multiple Strain Probiotics Reduces The Neurobehavioral Disorder in Premature Very Low Birth Weight Infants Related Papers Related Patents Related Grants Related Experts View Highlight: The management protocols, clinical practices, equipment, infrastructure, and key personnel in NICU are unchanged during the study period. The data collected by each center are transmitted to the office of the principal investigator (Dr Lin) at China Medical University Hospital. Primary outcome is death or attention deficit and hyperactivity disorder (ADHD) and ASD. |
HUNG-CHIH LIN; | 2018-06-14 |
| 488 | Effectiveness of Collaborative Tele-Mental Health Services for ADHD in Primary Care: A Randomized Trial in Dubai (ECTSAP- Dubai Trial) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Aim and objectives: In this study, our goal is to assess the effectiveness of a collaborative tele-mental health approach for treatment of children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) presenting to primary healthcare centers in Dubai. Our primary aim is: To determine if collaborative tele-mental health program improves the clinical and functional outcomes for children with Attention-deficit/hyperactivity disorder (ADHD) in Dubai Secondary aims: 1. To improve the ability of primary health-care providers to diagnose and treat pediatric ADHD, leading to enhanced community capacity, … |
AMMAR ALBANNA; | 2018-06-07 |
| 489 | Descriptive Epidemiology of A Specialized Consultation on Attention Deficit Hyperactivity Disorder in Adults at The Strasbourg University Hospital, and Evolution Analysis at One Year PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The main objective of this study is to carry out a descriptive study of the clinical and demographic characteristics of patients having consulted for a specialized opinion about ADHD in adults of the psychiatric service of the Strasbourg University Hospital. The characteristics of patients were collected during the first consultation, by the psychiatrist, and analyzed retrospectively. The secondary objective is to evaluate the evolution at one year in terms of follow-up, … |
UNIVERSITY HOSPITAL STRASBOURG FRANCE | 2018-06-01 |
| 490 | Developing and Evaluating A Metacognitive ADHD Telehealth Intervention for Work-performance Enhancement (Work-MATE) Amongst Adults With ADHD PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Adults with Attention-deficit hyperactivity disorder (ADHD) experience poor occupational performance at work compare to adults without ADHD, manifested at tendencies toward unemployment, job instability, work accidents, and sickness absences. This poor occupational performance at work may be partly caused by difficulties at executive functions (EF) abilities, and at the ability to set and attain goal directed work-activities at a satisfactory manner. Therefore, … |
SARA ROSENBLUM; | 2018-06-01 |
| 491 | The Effects of Peer Co-led Educational Group Intervention for Adults With Attention-Deficit Hyperactivity/Impulsivity Disorder PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Peer co-led education describes educators who are expert patients, user representatives or former patients, participating and teaching in educational interventions in cooperation with health care professionals. Peer co-led education is included in the Norwegian national guidelines for treatment of mental disorders, but despite some promising results for the treatment of other conditions, … |
NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY | 2018-05-31 |
| 492 | VidRT: Video Distraction During Radiation Therapy to Decrease Use of Pediatric Sedation Related Papers Related Patents Related Grants Related Experts View Highlight: This phase I pilot trial studies how well video distraction works to decrease the use of sedation in pediatric participants during radiation therapy. Radiation treatment requires participants to lie very still (for accuracy). Many children cannot do this without sedation. Watching movies during radiation may distract children so they don’t need sedation to complete treatment. |
JERRY JABOIN; | 2018-05-31 |
| 493 | A Text Messaging (SMS) Intervention to Improve Adherence to Stimulant Medication in Adults With ADHD in The Primary Care Setting PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will assess the efficacy of the text messaging (SMS-based) disease management intervention to improve adherence to stimulants in adults with Attention Deficit/Hyperactivity Disorder (ADHD) within the Partners primary and psychiatry care settings. Participants in the study will receive customized text messages twice a day, every day, for a duration of 9 months. The text messages will include reminders to adhere to the individualized medication regimen, reminders to call their clinician for a prescription refill followed by reminders to pick up medication from the pharmacy, and educational reminders about ADHD and its treatment |
JOSEPH BIEDERMAN; | 2018-05-24 |
| 494 | Speech Perception in Noise in Children With ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: We are going to assess an ability of speech perception in voice in children diagnosed with ADHD (Attention Deficit Hyperactivity Disorder), comparing to normal control group. This is an attempt to understand the factors influencing on this ability. |
MAYA ELAZAR; | 2018-05-22 |
| 495 | The Effects of Health Promotion Program for The Caregivers of Attention Deficit/Hyperactivity Disorders Children PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Objective: To explore the effect of health promotion programs on parental stress, quality of life, and health-promoting lifestyles for primary caregivers who had children with ADHD. Children’s ADHD symptoms were also examined. Methods: A randomized control trial was conducted between July 2017 and April 2018. Primary caregivers aged 20 to 65 years who had ADHD children aged 7 to 12 years were recruited from a psychiatric outpatient department. Sixty caregivers were randomized to the health promotion group intervention (n=30) and the control groups (n=30). The control group received usual care. Study instruments included the Swanson, Nolan, Pelham, Version IV (SNAP-IV), … |
TAIPEI MEDICAL UNIVERSITY | 2018-05-19 |
| 496 | Adaptive Response to Intervention (RTI) for Students With ADHD PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Purpose: The primary purpose of the proposed project is to investigate the efficacy of Tier 1 and Tier 2 interventions delivered through a Response to Intervention (RTI) framework for children with attention-deficit/hyperactivity disorder (ADHD). Further, for children who do not respond to initial Tier 2 strategies, the proposed study will assess which additional course of intervention is most effective: (1) enhanced Tier 2 strategies or (2) stimulant medication. The majority of youth with ADHD are in general education settings, whether classified as special education students or not. Thus, … |
FLORIDA INTERNATIONAL UNIVERSITY | 2018-05-14 |
| 497 | Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Male Children and Adolescents With Attention Deficit Hyperactivity Disorder: A Proof-of- Concept FMRI Study Related Papers Related Patents Related Grants Related Experts View Highlight: L-theanine and caffeine are two natural constituents of tea. Both of these compounds are among the U.S. Food and Drug Administration’s list of Generally Recognized as Safe (GRAS) substances. Results of several clinical trials the PI and his team has conducted are consistent with results of many others to indicate that oral intake of each of 2.5 mg/kg body weight of L-theanine and 2.0 mg/kg body weight of caffeine is associated with improved attention in adults. Furthermore, there is evidence to suggest that, when taken in combination, … |
CHANAKA KAHATHUDUWA; | 2018-05-14 |
| 498 | Pharmacokinetic Study of DYANAVEL XR (Amphetamine) Extended-release Oral Suspension, in Children Aged 4 to 5 Years With Attention-deficit/Hyperactivity Disorder Related Papers Related Patents Related Grants Related Experts View Highlight: The objective of this study was to evaluate the plasma amphetamine concentration/time profile of amphetamine extended release oral suspension in children aged 4 to 5 years with attention-deficit/hyperactivity disorder, following a single 2.5 mg dose of amphetamine extended release oral suspension. |
TRIS PHARMA | 2018-05-07 |
| 499 | Effect of RECOGNeyes Training on Brain Networks PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to keep their eyes on the task. Players use a small eyetracker to control the game with their eyes, giving their gaze-control system (oculomotor control system) a thorough work-out. This is a confidence-in-concept study to see whether RECOGNeyes holds promise as an approach to improving attentional control. It takes the form of a clinical trial, in which three groups of participants will undertake different amounts of RECOGNeyes training. The goals of the study are to find out: – … |
ELIZABETH LIDDLE; | 2018-05-04 |
| 500 | The Effects of Exercise Therapy on The Co-Morbidity of Attention Deficit and Hyperactivity Disorder (ADHD) and Developmental Co-Ordination Disorder. (DCD) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to establish and present the prevalence figures and demographics of the co-morbidity of ADHD and DCD. It further aims to design an exercise intervention, to be utilised in the management of the symptoms of both conditions. Furthermore, it aims at establishing the efficacy of this exercise intervention, when compared with the current and most commonly used intervention, that is: neurostimulant drugs. |
PAM DAWSON; | 2018-05-02 |