Clinical Digest: Recent Clinical Trials on Trichomonas Infection
To assist researchers and healthcare practitioners in staying up-to-date with the latest advancements in clinical research, the Clinical Digest Team has compiled a comprehensive list of recent clinical trials related to Trichomonas Infection. These trials are organized by their release dates for your convenience. (Last updated on: 2025-05-02)
This curated list is brought to you by the Clinical Digest Team. Experience the cutting-edge capabilities of Clinical Digest, an innovative AI-powered clinical research platform that empowers you to read articles, write articles, get answers, conduct literature reviews and generate research reports.
Experience the full potential of our services today!
TABLE 1: Clinical Digest: Recent Clinical Trials on Trichomonas Infection
| Clinical Trial | Contact(s) | Date | |
|---|---|---|---|
| 1 | Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: A prospective interventional study to evaluate a strategy of point-of-care testing for sexually transmitted infections including chlamydia, gonorrhoea, trichomoniasis, syphilis, and Hepatitis B with comprehensive case management including partner notification in antenatal settings in Harare province, Zimbabwe. |
KEVIN MARTIN; | 2023-01-12 |
| 2 | Oral Tinidazole Treatment of Refractory Trichomonas Vaginitis PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: We compare two oral tinidazole regimens for refractory trichomonas vaginitis. |
SHANGRONG FAN; | 2022-12-01 |
| 3 | Acceptability Research on Integrated Point of Care Sexually Transmitted Infection (STI) Testing and Expedited Partner Therapy (EPT) PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This protocol builds on nearly a decade of collaborative HIV/STI prevention research to conduct a prospective cohort study of Adolescent Girls and Young Women (AGYW) eligible for PrEP in South Africa in which we will assess the acceptability of point-of-care STI testing plus Expedited Partner Therapy (EPT) and its impact on the incidence of common curable STIs over 12 months of follow-up. The social-behavioral scientist will undertake qualitative interviews with participants and their male partners to identify facilitators and barriers to EPT uptake and conduct a comparative cost analysis to estimate the cost per person tested using point-of-care STI testing with and without EPT incremental to the cost of standard of care. Findings from the proposed research will provide essential knowledge for national policymakers to advance approaches to STI screening and treatment that will lead to improvements in AGYW sexual reproductive health and reductions in STIs. The data generated from this project are essential to inform efforts to reduce the burden of STIs and HIV-1 in women and achieve the 2030 Sustainable Development Goals, which includes substantial reductions in HIIV and STIs in key at-risk populations. This project will support global efforts to substantially reduce STIs in key populations. |
THESLA PALANEE-PHILLIPS; | 2022-02-11 |
| 4 | A Pilot Study to Evaluate The Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and PH PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Most of the methods involved in the treatment of BV include antibiotics. Some of the antibiotics used for this include metronidazole, clindamycin and fluconazole. The antibiotics inhibit the growth of anaerobes that support G. vaginalis and other microbes without affecting lactobacilli. This leads to the treatment of BV while also preventing its recurrence. However, the use of antibiotics may lead to antibiotic resistance and cause various side-effects such as thrush, dizziness, rash, nausea, etc. In the case of many antibiotics, … |
KAMLESH KUMARI; | 2022-01-03 |
| 5 | Multilevel Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: To achieve an AIDS-free generation, there is a critical need for programs which go beyond individual-level behavior change to reduce HIV and STI infections among adolescent girls and young women in sub-Saharan Africa. Informed, Motivated, Aware, and Responsible Adolescents and Adults (IMARA) is an evidence-based HIV-prevention intervention for adolescent girls and young women (AGYW) and their female caregivers, … |
GERI DONENBERG; | 2021-10-02 |
| 6 | A Prospective, Open-Label, Pilot, Multicentric Clinical Investigation to Evaluate The Performance and Safety of Cerviron Ovules® in The Local Treatment of Non-Specific or Endogenous, Symptomatic Vaginitis PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: CYRON is a Prospective, Open-Label, Pilot, Multicentric Clinical Investigation to Evaluate the Performance and Safety of Cerviron Ovules® in the Local Treatment of Non-Specific or Endogenous, Symptomatic Vaginitis. The primary objective is to assess the therapeutic performance and tolerability of Cerviron® Ovules in patients with symptomatic, non-specific, non-infectious vaginitis, and endogenous symptomatic infections. The secondary objective of this clinical investigation is the assessment of performance of the medical device by several additionally clinical outcomes (vaginal discharge, vaginal pH, … |
PERFECT CARE DISTRIBUTION | 2021-04-01 |
| 7 | Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes PF:6 Related Papers Related Patents Related Grants Related Experts View Highlight: This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes. In turn it aims to evaluate the cost per pregnant woman screened and treated, cost of adverse birth outcomes, and cost-effectiveness per sexually transmitted infection (STI) and disability-adjusted life-year (DALY) averted. Furthermore, … |
ANDREW MEDINA-MARINO; | 2021-03-29 |
| 8 | Vaginal and Rectal Colonization of Lactobacillus Crispatus NTCVAG04 Following Oral Administration in Patients With History of Vaginitis/Vaginosis PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to identify the presence of L. Crispatus in the rectum and vagina after oral administration of BIOVAGINIL by searching for specific DNA of the bacterial strain, to evaluate the tolerability of BIOVAGINIL and evaluate the minimum duration of the oral administration necessary to determine the appearance of L. Crispatus. |
VINCENZO DE LEO; | 2019-11-22 |
| 9 | Multi-center, Prospective, Randomized, Placebo-Controlled, Delayed Treatment, Double-Blind Study to Evaluate The Effectiveness and Safety of A Single Oral Dose of Solosec® for The Treatment of Trichomoniasis PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a Phase 3, multi-center, prospective, randomized, placebo-controlled, delayed treatment, double-blind, study to evaluate the effectiveness, and safety of a single, oral dose of Solosec® containing 2 grams of secnidazole in female patients with trichomoniasis. |
LUPIN RESEARCH | 2019-04-23 |
| 10 | Trichomonas Vaginalis Genotyping in Upper Egypt PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The worldwide incidence of trichomoniasis was estimated to be 276.4 million new cases per year in 2008 .In Egypt, the reported prevalence rate ranges from 5% to 79.16% we aim to study genetic variability of Trichomonas vaginalis using PCR |
NASSER MOHAMED ABDELKAREEM; | 2018-10-01 |
| 11 | Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: To determine the effect of performing internal vaginal douching on the frequency and severity and type of vaginal infections in IUD users |
AHMED MOHAMED ALAAELDIN MAHMOUD YOUSSEF; | 2018-06-01 |
| 12 | An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess The Efficacy and Safety of Morinidazole With Surgery in Patients With Suppurative or Gangrenous Appendicitis PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: To assess the efficacy, safety, tissue distribution of target organ and Population Pharmacokinetic (PPK) of morinidazole and sodium chloride injection with surgery in patients with suppurative or gangrenous appendicitis |
JIANGSU HANSOH PHARMACEUTICAL | 2016-09-01 |
| 13 | Use of Condoms in Prevention of Progression of Cervical Intraepithelial Neoplasia: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Women who are diagnosed with CIN2 and who have a pregnancy wish are followed up 6 months after the diagnosis with new examinations. The regression rate is based solely on the woman’s own ability to clear the cervical lesions. The use of condoms has shown a relatively good protective effect against Human Papillomavirus (HPV) infection. It has furthermore been indicated that condoms increase the regression rate of cervical lesions. The hypothesis of this study is that the regression rate of cervical intraepithelial neoplasia grade 2 (CIN2) increases when condoms are used consistently in the follow-up period of 6 months. |
MALENE SKORSTENGAARD; | 2016-09-01 |
| 14 | An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess The Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: To assess the efficacy, safety and Population Pharmacokinetic (PPK) of morinidazole and sodium chloride injection with levofloxacin hydrochloride and sodium chloride injection sequential of levofloxacin hydrochloride tablets in women with pelvic inflammatory disease: An Open-Lable Multicenter Prospective Non-Randomized Trial |
JIANGSU HANSOH PHARMACEUTICAL | 2016-09-01 |
| 15 | Changing The STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of this prospective cohort study is to determine if a model of care including point-of-care testing, immediate therapy, expedited partner therapy and test of cure will result in a higher cure rate and a lower recurrence rate of sexually transmitted infections (STIs), with a subsequent reduction in genital inflammatory cytokines and hence HIV risk among young women in a high burden setting in KwaZulu-Natal, South Africa. The study will identify individuals with STIs using the GeneXpert system for the simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis, … |
NIGEL GARRETT; | 2016-05-15 |
| 16 | A Randomized Study Evaluating An Intervention Integrating Economic Strengthening and HIV Prevention Programs for Vulnerable Youth in South Africa PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: This study evaluates whether the integration of an Economic Strengthening program with an HIV-prevention education program produce synergistic effects on economic and health outcomes for South African youth ages 14-17 years old. |
HOLLY BURKE; | 2016-02-01 |
| 17 | Validity of Patient-Collected Wet Mounts PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Purpose/Objectives: To compare wet mount findings for clue cells, yeast, trichomonads and white blood cells per high-power field in self-collected vaginal specimens, compared to clinician-collected specimens, among symptomatic women visiting the San Antonio Metropolitan Health sexually transmitted disease clinic. Research Design/Plan: Prospective, non-randomized, non-blinded trial Methods: Obtain informed consent and specimens from 40 symptomatic adult females (eg abnormal discharge, odor and/or itching). Calculate concordance between clinician- and patient-collected samples using a Wilcoxon Matched-Pair test. Calculate sensitivity, specificity, positive predictive value and negative predictive value of the patient-collected wet mount, … |
JUNDA WOO; | 2015-11-01 |
| 18 | Assessment of The Efficacy of POLYGYNAX® in The Empirical Treatment of Infectious Vaginitis International, Multicentre, Randomised, Double-blind, Parallel Group Study, Comparative Versus Miconazole PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: POLYGYNAX® is a broad spectrum combination of nystatin, neomycin and polymixin B indicated for the local treatment of vaginitis due to sensitive germs and treatment of non specific vaginitis of adults. POLYGYNAX® has been marketed in France since 1969. Nevertheless, despite the well established use of POLYGYNAX®, there is no clinical study supporting the interest of the combination of antifungal and antibiotics agents versus antifungal agent alone. The aim of this project is to demonstrate that POLYGYNAX® is more effective than miconazole in the treatment of women experiencing symptoms of infectious vaginitis. |
JEAN-MARC BOHBOT; | 2015-09-01 |
| 19 | Evaluating A Microfinance Intervention for Vulnerable Women in Kazakhstan PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will examine the efficacy of a combined HIV and microfinance intervention to reduce biologically confirmed sexually transmitted infections (STIs), and new incidence of HIV and HCV, as well as reported sexual and drug risk behaviors among 520 women who have injected drugs in the past year and who engage in sex trading in Temirtau and Pavlodar, Kazakhstan. The proposed study builds on findings from an R34 by the investigative team testing a combination HIV prevention and microfinance intervention. Building on successful protocols and significant results, … |
SUSAN WITTE; | 2015-04-01 |
| 20 | Validation of A Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Bacterial vaginosis (BV) is the commonest form of vaginitis worldwide, affecting millions of women. Unfortunately, recurrence rates of symptomatic BV remain extremely high, 30% at three months and 70-80% within a year. Given the paucity of information and data regarding pathogenesis of BV, the etiopathogenesis of recurrent bacterial vaginosis remains unknown. Accordingly, reliable, proven treatment regimens for Recurrent Bacterial Vaginosis (RBV) are not available. In 2013, the investigators published two manuscripts documenting a new qPCR based approach to BV diagnosis and potentially prognosis. The method (LbRC) measures the content of lactobacilli in vaginal samples, … |
ROBERT A. AKINS; | 2014-09-01 |
| 21 | Comparing NAAT Testing to Standard Methods in Diagnosis of Vaginal Infections in The General Gynecology and Vulvovaginal Referral Offices PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Vaginitis is the most common condition encountered in the gynecologist’s office and is most commonly caused by bacerial vaginosis (BV), vulvovaginal candidiasis (VVC) and Trichomonas vaginalis (TV). Establishing the correct etiology of symptomatic vaginitis can be challenging, and the evaluation of vaginitis by physicians is often substandard. The investigators will determine whether NAAT testing will improve the diagnosis of vaginal infections including bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and Trichomonas vaginalis (TV). |
HAROLD WIESENFELD; | 2014-07-01 |
| 22 | Rapid HIV Testing and Counseling in High Risk Women in Shelters PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a developmental study evaluating a new rapid HIV testing and risk prevention intervention for residents of battered women’s shelters who endorse risky sexual behaviors. |
DAWN JOHNSON; | 2013-01-01 |
| 23 | Repeat STI Patients: Tailored Socio-Contextual Intervention to Reduce HIV Risk PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: People who present repeatedly at Sexually Transmitted Infection (STI) clinics represent a key population for HIV prevention intervention research. Despite their heightened risk there is an absence of empirical research on strategies to intervene with repeat STI. Some STI-clinic based behavioral HIV prevention studies, focusing on the general STI patient population, have found that risk reduction interventions can reduce the incidence of a subsequent STI. Studies have shown that expedited treatment for STI patients’ partners can reduce subsequent STI and enhancing partner notification can reduce risk for repeat infection. Those who go on to experience repeat infections, … |
LANCE WEINHARDT; | 2012-04-01 |
| 24 | Neo-Penotran Forte Vaginal Suppository for Vaginal Trichomoniasis PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The investigators are trying a combination vaginal product of higher dose metronidazole combined with miconazole to see if it is effective in treating vaginal trichomonas. |
JANE SCHWEBKE; | 2011-12-01 |
| 25 | Project AWARE: Using The ED to Prevent STIs in Youth Related Papers Related Patents Related Grants Related Experts View Highlight: Project Aware introduces a sexually transmitted infection (STI) screening model for sexually experienced adolescents aged 14 to 21 in a large, inner-city Emergency Department (ED) in the Bronx, N.Y. Project Aware will scaffold routine, rapid testing and counseling for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) onto an existing, successful, ED-based HIV testing and counseling program, Project BRIEF. Project Aware will educate and motivate youth to use condoms with the aid of a theory-based, youth-friendly multimedia behavioral intervention proven to be effective during the investigator’s K23 training. Through Project Aware, … |
YVETTE CALDERON; | 2011-12-01 |
| 26 | HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The pilot study aims to conduct a randomized pilot trial in a sample of 40 incarcerated women with lifetime interpersonal violence who are 6-10 weeks away from release to demonstrate the feasibility and acceptability of the proposed recruitment methods and research design, of the intervention training methods, of delivering the enhanced Women’s Coop and nutrition control interventions. Per recent guidance from NIMH, the investigators will also examine 95% confidence intervals around differences between the proposed intervention and a dose-matched control condition (Nutrition Program), … |
JENNIFER JOHNSON; | 2011-09-01 |
| 27 | Sexually Transmitted Infections Among African American Women Who Have Sex With Women PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to determine rates of sexually transmitted infections (STIs) among African American women who have sex with women (AAWSW). In addition, the study is interested in better understanding the types of risk behaviors that place AAWSW at risk for STIs. The investigators hypothesis is that AAWSW experience high rates of STIs, similar to heterosexual African American women. Knowledge gained from this study will guide development of interventions to reduce women’s risk for these types of infections and will improve how AAWSW are screened for STIs. |
CHRISTINA MUZNY; | 2011-08-01 |
| 28 | A Case Control Study of Women With Multiple Sexual Partners Attending The Jefferson County Department of Health Sexually Transmitted Diseases Clinic PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Both population based surveys and more focused research studies indicate that increased numbers of sexual partners and partner concurrency contribute to increased risk for acquisition of sexually transmitted infection (STI), including HIV infection. However, unlike for men, both national and sub-population-based studies consistently find that the great majority of women with or without STIs report only 1-2 sex partners in the preceding year and that a minority of women acknowledge > 3 sex partners over the same period, … |
CHRISTINA MUZNY; | 2011-05-01 |
| 29 | HIV Prevention for STD Clinic Patients PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will determine whether showing an educational DVD to people at sexually transmitted infection clinics can reduce incidence of new infections and risky sexual behaviors and improve overall health. |
MICHAEL P. CAREY; | 2009-10-01 |
| 30 | Trichomoniasis: Genotype and Phenotype Correlations in African American Women PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: The hypothesis to be tested in this trial is that the different epidemiologic (including racial differences) and phenotypic manifestations exhibited by Trichomonas clinical isolates during infection are correlated with their genotypic strain classification. Two specific aims are proposed to test that hypothesis. Specific aim 1. Assess the significance of genotypic or phenotypic differences in the Trichomonas strains among African American women by HIV status. Specific aim 2. Determine the significance of genotypic or phenotypic differences in the Trichomonas strains circulating among women from two different racial groups, … |
JOHN C MEADE; | 2009-09-01 |
| 31 | Management of Vaginal Complaints: A Pilot Study Within A Practice-Based Research Network PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Many women present in primary care with vaginal complaints. The best way of managing these complaints is unclear. This trial will test two different methods of managing patients with vaginal complaints. This is a pilot trial. |
MATTHEW R. ANDERSON; | 2007-02-01 |
| 32 | A Comparison Study of The WaterWorks® Douching Device Vs. Commercial OTC Douching Device for The Reduction or Abatement of Perceived Vaginal Odor With or Without Complaints of Discharge in Women With No Infectious Causes of Vaginitis PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Comparing the new Stainless Steel WaterWorks® douching device to a commercially available douching device using just water for safety and efficacy of odor abatement. |
ASHWIN CHATWANI; | 2006-08-01 |
| 33 | Tinidazole for The Treatment of Bacterial Vaginosis PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: We are trying to determine if treatment of bacterial vaginosis with tinidazole is better than treatment with metronidazole |
JANE SCHWEBKE; | 2004-11-01 |
| 34 | South African Adolescent Health Promotion Project PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: This study will evaluate the effect of an HIV/STD risk-reduction program on the sexual behavior of South African adolescents. |
JOHN JEMMOTT; | 2004-10-01 |
| 35 | Control of Trichomoniasis – A Paradigm for STD Control PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: This study is designed to try to find the best method of partner notification and treatment for partners of women with trichomonas |
JANE SCHWEBKE; | 2003-05-01 |
| 36 | HIV Prevention Preparedness Study PF:5 Related Papers Related Patents Related Grants Related Experts View Highlight: The purpose of this study is to provide researchers with information that will help them prepare for a future study to test the efficacy of two anti-HIV vaginal gels. This study will also estimate how likely people living in certain areas are to become infected with HIV and other infections passed during sex. |
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES NIAID | 2002-10-29 |
| 37 | STARS: Sistas Talking About Real Solutions PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: STARS: Sistas Talking About Real Solutions is a health education intervention for African-American women, ages 18-29 aimed at reducing their risk for HIV. A total of 855 subjects were recruited from three Kaiser Permanente Medical Centers. Members were randomly selected from the membership database and sent a letter via mail introducing them to the project and inviting them to participate. Letters were followed up with a phone call and potential participants were screened for eligibility. To be able to participate, participants had to be African-American, female, between the ages of 18-29, single, … |
GINA M WINGOOD; | 2002-10-01 |