Clinical Digest: A Comprehensive Review of Recent Eli Lilly Patents
This compilation provides an overview of Eli Lilly‘s latest patent inventions. Alongside these patents are potentially related patents, which may include work from Eli Lilly or other entities exploring similar therapeutic areas. This resource aims to offer researchers, clinicians, investors, and the broader public insights into Eli Lilly’s current research and development pipeline. By presenting patent details alongside related intellectual property (regardless of origin), this compilation facilitates a broader understanding of Eli Lilly’s strategic focus and how it potentially compares to direct and indirect competitors in these therapeutic spaces. This information can be valuable for identifying emerging trends in drug development, assessing the commercial potential of specific research programs, and understanding the broader landscape of scientific contributions related to Eli Lilly’s patent inventions. (Last updated on: 2025-05-22)
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TABLE 1: Clinical Digest: A Comprehensive Review of Recent Eli Lilly Patents
| Title | Applicant/Assignee | Filing Date | Publish Date | Grant Date | |
|---|---|---|---|---|---|
| 1 | COMPOUNDS FOR THE TREATMENT OF DIABETES OR OBESITY Related Patents View Abstract: The present disclosure relates to novel urocortin-2 polypeptides, having activity at the corticotropin-releasing hormone receptor-2 (CRHR2), pharmaceutical compositions comprising … |
ELI LILLY | 2024-11-15 | 2025-05-22 | |
| 2 | PHAGE DISPLAY-BASED CELL-PENETRATING PEPTIDE DISCOVERY PLATFORM AND METHODS OF MAKING AND USING THE SAME Related Patents View Abstract: Engineered bacteriophages are disclosed that include modifications in a pIII surface coat protein, especially in at least one of a GS1 and GS2 linker to include a peptidase … |
ELI LILLY | 2023-02-16 | 2025-05-22 | |
| 3 | DOSE DETECTION SYSTEM MODULE FOR A MEDICATION DELIVERY DEVICE Related Patents View Abstract: Dose detection systems for medication delivery devices are described. One is a module for removable attachment to a dose button of a medication delivery device. A device with a … |
ELI LILLY | 2025-01-16 | 2025-05-15 | |
| 4 | COMMUNICATION TAG FOR A DRUG PRODUCT Related Patents View Abstract: A medication delivery device is provided having a housing comprising a reservoir sized sufficiently to hold medication, an actuating button for initiating an injection of the … |
ELI LILLY | 2023-01-27 | 2025-05-15 | |
| 5 | SYSTEMS AND METHODS FOR INTERNAL DRUG LOADING FOR INFUSION PROCESSES Related Patents View Abstract: Methods for applying a therapeutic agent coating to an extended-wear device and the systems created thereby are disclosed. For example, a method for coating an extended-wear … |
ELI LILLY | 2023-02-15 | 2025-05-08 | |
| 6 | SOLID PHASE PEPTIDE SYNTHESIS WASH PROCESS Related Patents View Abstract: A method is disclosed for washing an amino acid that has been added to a solid phase resin during solid phase peptide synthesis (SPPS), comprising: … |
ELI LILLY | 2023-02-13 | 2025-05-08 | |
| 7 | METHODS AND SYSTEMS FOR DETECTING EVENTS USING ACTIGRAPHY DATA Related Patents View Abstract: A computerized method is provided for detecting whether a subject is experiencing an event (e.g., an eating event or a scratching event). The method may comprise receiving … |
ELI LILLY | 2023-01-30 | 2025-05-01 | |
| 8 | TUBING HAVING VISUAL MARKERS FOR VISUALIZATION OF MEDIA THEREIN Related Patents View Abstract: A transparent tubing is provided comprising a longitudinal axis having a center; an inner circumferential surface defining a fluid pathway therethrough for delivering a first … |
ELI LILLY | 2024-12-19 | 2025-04-17 | |
| 9 | FGFR3 INHIBITOR COMPOUNDS Related Patents View Abstract: The present invention provides compounds of the formula: for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia, thanatophoric … |
ELI LILLY | 2024-12-09 | 2025-04-17 | |
| 10 | ANTIBODY OPTIMIZATION Related Patents View Abstract: The present disclosure relates to methods of developing, designing, and producing therapeutic antibodies to improve developability of an antibody or antibody drug conjugate. … |
ELI LILLY | 2022-08-05 | 2025-04-17 | |
| 11 | KRAS INHIBITORS Related Patents View Abstract: The present invention provides compounds of the formula: wherein A, Z, G, R , R , and R are as described herein, pharmaceutically acceptable salts thereof, and methods of using … |
ELI LILLY | 2024-09-26 | 2025-03-27 | |
| 12 | FLUIDIZED BED GRANULATION AND COATING SYSTEMS AND METHODS Related Patents View Abstract: A fluidized bed granulation (FBG) system includes a pre-wetting subsystem, wherein feedstock is pre-wet to a predetermined % value, a fluidization chamber (FC), an inlet coupled … |
PURDUE RESEARCH FOUNDATION et. al. | 2024-09-26 | 2025-03-27 | |
| 13 | COMPOUNDS AND METHODS TARGETING EPIREGULIN Related Patents View Abstract: The present invention relates to epiregulin antibodies, compositions comprising the same, and methods of making and/or using the antibodies and/or compositions thereof for chronic … |
ELI LILLY | 2024-06-26 | 2025-03-27 | |
| 14 | NEUREGULIN-4 COMPOUNDS AND METHODS OF USE Related Patents View Abstract: The present invention relates to neuregulin (NRG) 4 compounds and methods of treatment with NRG4 compounds. … |
ELI LILLY | 2024-09-19 | 2025-03-20 | |
| 15 | TECHNIQUES FOR PROCESSING WIRELESSLY BROADCAST PACKETS FROM A MEDICAL DEVICE WITH DOSE-RELATED DATA Related Patents View Abstract: A computing device is provided having a processor in communication with a memory configured to store machine-readable instructions. The processor can receive, from a wireless … |
ELI LILLY | 2024-11-18 | 2025-03-06 | |
| 16 | AT2R ANTAGONISTS AND USES THEREOF Related Patents View Abstract: This invention provides certain piperidine compounds as AT R antagonists. e.g., compounds of formula (I): … |
ELI LILLY | 2024-09-06 | 2025-03-06 | |
| 17 | AMYLOID PRECURSOR PROTEIN (APP) RNAi AGENTS Related Patents View Abstract: Provided herein are APP RNAi agents and compositions comprising an APP RNAi agent. Also provided herein are methods of using the APP RNAi agents or compositions comprising an APP … |
ELI LILLY | 2024-08-16 | 2025-02-27 | |
| 18 | REGIONAL TAU IMAGING FOR DIAGNOSING AND TREATING ALZHEIMER’S DISEASE Related Patents View Abstract: Disclosed are methods for using regional tau PET scans for identifying a subject having or suspected of having, diagnosing, and treating Alzheimer’s disease. The methods are … |
ELI LILLY | 2023-01-30 | 2025-02-27 | |
| 19 | INCRETIN ANALOGS AND USES THEREOF Related Patents View Abstract: Incretin analogs are provided that have activity at each of the GIP, GLP-1 and glucagon receptors. The incretin analogs have structural features resulting in balanced activity and … |
ELI LILLY | 2024-09-23 | 2025-02-20 | |
| 20 | PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Related Patents View Abstract: The present invention provides novel intermediates and processes useful in the manufacture of tirzepatide, or a pharmaceutically acceptable salt thereof. … |
ELI LILLY | 2024-08-12 | 2025-02-20 | |
| 21 | GIP/GLP1 CO-AGONIST COMPOUNDS Related Patents View Abstract: The present invention relates to compounds having activity at both the human glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The … |
ELI LILLY | 2024-10-18 | 2025-02-13 | |
| 22 | DOSING REGIMENS FOR SELECTIVE TREG STIMULATOR RUR20kD-IL-2 AND RELATED COMPOSITIONS Related Patents View Abstract: The instant disclosure provides selective Treg stimulator compositions, including RUR20kD-IL-2 and related compositions, and rezpegaldesleukin, and formulations and dosing … |
NEKTAR THERAPEUTICS et. al. | 2022-12-14 | 2025-02-13 | |
| 23 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR Related Patents View Abstract: The present invention relates to the synthesis of … |
ELI LILLY | 2024-09-03 | 2025-02-06 | |
| 24 | ANTI-IL-1-BETA ANTIBODIES Related Patents View Abstract: The present invention provides engineered human interleukin-1 beta antibodies, cells and vectors comprising DNA encoding the same, and methods for producing the antibodies. In … |
ELI LILLY | 2022-09-12 | 2025-02-06 | |
| 25 | Treatment of Hand Eczema with Baricitinib Related Patents View Abstract: Methods of treating Hand Eczema with baricitinib, including formulations and dose regimens. The amount of baricitinib may be administered as a 4 mg tablet or pill that includes … |
ELI LILLY | 2022-07-29 | 2025-02-06 | |
| 26 | METHODS OF TREATING ULCERATIVE COLITIS Related Patents View Abstract: The present invention generally relates to the treatment of ulcerative colitis with an anti-IL-23p19 antibody, in particular dosage regimens for the treatment of the disease. … |
ELI LILLY | 2024-10-16 | 2025-01-30 | |
| 27 | FUSION PROTEINS Related Patents View Abstract: The present invention relates to fusion proteins comprising an insulin receptor agonist fused to a human IgG Fc region through the use of a peptide linker, and the use of such … |
ELI LILLY | 2024-06-27 | 2025-01-30 | |
| 28 | SYSTEMS AND METHODS FOR IDENTIFYING SUBJECTS FOR CLINICAL TRIALS Related Patents View Abstract: A computing device is provided having a processor in communication with a memory configured to store machine-readable instructions. The processor can access data indicative of … |
ELI LILLY | 2022-11-16 | 2025-01-30 | |
| 29 | LONG-ACTING AMYLIN RECEPTOR AGONISTS AND USES THEREOF Related Patents View Abstract: The present disclosure relates to the field of medicine. More particularly, the disclosure is in the field of treatment of diabetes, obesity and/or chronic weight management, … |
ELI LILLY | 2024-09-12 | 2025-01-23 | |
| 30 | PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACETATE Related Patents View Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of … |
ELI LILLY | 2024-09-27 | 2025-01-16 | |
| 31 | GLUCAGON-LIKE PEPTIDE1 RECEPTOR AGONISTS Related Patents View Abstract: In an embodiment, the present invention provides a compound of the formula: or a pharmaceutically acceptable salt thereof, and methods of using this compound for treating type II … |
ELI LILLY | 2024-09-09 | 2025-01-02 | |
| 32 | NECTIN-4 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Related Patents View Abstract: The present disclosure provides nectin-4 antibody drug conjugates and pharmaceutical compositions thereof, and methods of using for the treatment of cancer. … |
ELI LILLY | 2024-06-19 | 2025-01-02 | |
| 33 | COMPOUNDS FOR THE DELIVERY OF GRANULIN ACROSS THE BLOOD BRAIN BARRIER Related Patents View Abstract: Compounds for the delivery of progranulin, a progranulin fragment, and/or at least one granulin protein subunit across the blood brain barrier. Compounds for the delivery of … |
ELI LILLY | 2024-06-18 | 2025-01-02 | |
| 34 | FORMULATIONS AND DOSING REGIMENS FOR RIP1 KINASE INHIBITORS FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES Related Patents View Abstract: Disclosed herein are methods of treating a subject having an autoimmune or inflammatory disease, and formulations associated therewith, comprising administering to the patient a … |
ELI LILLY et. al. | 2024-06-17 | 2025-01-02 | |
| 35 | THERAPEUTIC AGENT DELIVERY DEVICE WITH SINGLE MOTOR DRIVE Related Patents View Abstract: A therapeutic agent delivery device includes a syringe assembly having a plunger, a drive mechanism, and a shuttle system coupled to a syringe of the syringe assembly. The drive … |
ELI LILLY | 2023-01-31 | 2025-01-02 | |
| 36 | PRESERVED FORMULATIONS Related Patents View Abstract: Described herein are preserved formulations of insulin-Fc fusions. The formulations include insulin-Fc fusions having prolonged pharmacokinetic and pharmacodynamic profiles … |
ELI LILLY | 2022-11-14 | 2025-01-02 | |
| 37 | DEUTERATED (TRIFLUOROMETHYL)PYRIMIDINE-2-AMINE COMPOUNDS AS POTENTIATORS OF THE HMRGX1 RECEPTOR Related Patents View Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, useful for treating pain, including chronic pain, chronic lower back pain, … |
ELI LILLY | 2022-11-07 | 2025-01-02 | |
| 38 | INSERTER DEVICES PROVIDING MANUAL INSERTION AND AUTOMATIC RETRACTION Related Patents View Abstract: Inserter devices provide manual insertion of an insertion needle and cannula and subsequent automatic retraction of the insertion needle. The inserter devices include insertion … |
ELI LILLY | 2022-10-26 | 2025-01-02 | |
| 39 | THERAPEUTIC AGENT DELIVERY DEVICE WITH USER INPUT Related Patents View Abstract: A therapeutic agent delivery device includes a disposable portion and a reusable portion that detachably carries the disposable portion. The reusable portion includes a drive … |
ELI LILLY | 2022-08-19 | 2025-01-02 | |
| 40 | PAN-ELR+ CXC CHEMOKINE ANTIBODIES FOR THE TREATMENT OF HIDRADENITIS SUPPURATIVA Related Patents View Abstract: Provided herein are methods and uses of antibodies against ELR+CXC chemokines for the treatment of hidradenitis suppurativa. Also provided are doses and dosing regimens for the … |
ELI LILLY | 2024-06-05 | 2024-12-26 | |
| 41 | TREATMENT OR PREVENTION OF NEW-ONSET TYPE 1 DIABETES WITH BARICITINIB Related Patents View Abstract: The present invention provides methods of treating or preventing new-onset type 1 diabetes with baricitinib, either alone or in combination with insulin, insulin analogues and/or … |
ELI LILLY | 2024-05-17 | 2024-12-26 | |
| 42 | STABILIZER FOR MEDICATION DELIVERY DEVICE Related Patents View Abstract: The present disclosure relates to a medication delivery device including a stabilizing apparatus for effective delivery of a dose of medication without interference with various … |
ELI LILLY | 2022-10-04 | 2024-12-12 | |
| 43 | ENGINEERED ANTIBODY COMPOUNDS AND CONJUGATES THEREOF Related Patents View Abstract: Engineered antibody compounds and conjugates thereof, are provided, said antibody compounds and conjugates thereof are useful as agents for cancer immunotherapy. Engineered … |
ELI LILLY | 2024-08-19 | 2024-12-05 | |
| 44 | PROCESSES AND INTERMEDIATES FOR PREPARING TIRZEPATIDE Related Patents View Abstract: The present invention provides new intermediates and processes useful in the manufacture of tirzepatide, or a pharmaceutically acceptable salt thereof. … |
ELI LILLY | 2024-08-15 | 2024-12-05 | |
| 45 | THREE RESIN REACTORS IN SERIES PEPTIDE SYNTHESIZER Related Patents View Abstract: A Solid Phase Peptide Synthesis (SPPS) device and method of using the same for manufacturing peptides is taught herein. The system comprises at least two reactors, each reactor … |
ELI LILLY | 2024-08-13 | 2024-12-05 | |
| 46 | CDK4 AND 6 INHIBITOR IN COMBINATION WITH FULVESTRANT FOR THE TREATMENT OF HORMONE RECEPTOR-POSITIVE, HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2-NEGATIVE ADVANCED OR METASTATIC BREAST CANCER IN PATIENTS PREVIOUSLY TREATED WITH A CDK4 AND 6 INHIBITOR Related Patents View Abstract: Disclosed are methods, uses, and combinations for treating hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HIER2−) advanced or metastatic … |
ELI LILLY | 2022-12-07 | 2024-12-05 | |
| 47 | PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Related Patents View Abstract: The present invention provides novel intermediates and processes useful in the manufacture of tirzepatide, or a pharmaceutically acceptable salt thereof. … |
ELI LILLY | 2024-08-12 | 2024-11-28 | |
| 48 | ANTIBODIES TARGETING XCL1 AND METHODS OF USING THE SAME Related Patents View Abstract: The present invention provides compounds and methods targeting human lymphotactins, including therapeutic antibodies, pharmaceutical compositions and methods of use thereof, … |
ELI LILLY | 2024-05-24 | 2024-11-28 | |
| 49 | ANTI-IL-23P19 ANTIBODY REGULATION OF GENES INVOLVED IN BOWEL URGENCY IN ULCERATIVE COLITIS Related Patents View Abstract: The present disclosure is generally relates to methods of treating ulcerative colitis. The methods are particularly suitable for treating bowel urgency a specific sub-group of … |
ELI LILLY | 2022-09-30 | 2024-11-28 | |
| 50 | SYSTEMS AND METHODS FOR SENSING DEFECATION EVENTS Related Patents View Abstract: Systems and methods facilitate sensing and tallying defecation events of subjects, such as participants in clinical trials for treatments for treating digestive diseases, such as … |
ELI LILLY | 2022-09-01 | 2024-11-14 | |
| 51 | THERAPEUTIC AGENT DELIVERY DEVICE INCLUDING DISPOSABLE AND REUSABLE PORTIONS Related Patents View Abstract: A therapeutic agent delivery device includes a disposable portion and a reusable portion that detachably carries the disposable portion. The reusable portion includes a drive … |
ELI LILLY | 2022-08-19 | 2024-11-14 | |
| 52 | PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Related Patents View Abstract: The present invention provides novel intermediates and processes useful in the manufacture of tirzepatide, or a pharmaceutically acceptable salt thereof. … |
ELI LILLY | 2024-06-24 | 2024-11-07 | |
| 53 | KRAS INHIBITORS Related Patents View Abstract: The present invention provides compounds of the formula: wherein A, Z, G, R , R , and R are as described herein, pharmaceutically acceptable salts thereof, and methods of using … |
ELI LILLY | 2024-03-29 | 2024-11-07 | |
| 54 | BISPECIFIC ANTI-FLT3/CD3 ANTIBODIES AND METHODS OF USE Related Patents View Abstract: Provided herein are bispecific anti-FLT3/CD3 antibodies and antigen binding fragments thereof, such as the antibodies and fragments that specifically bind human FLT3 and human … |
HEMOGENYX PHARMACEUTICALS et. al. | 2022-08-15 | 2024-11-07 | |
| 55 | KRAS INHIBITORS Related Patents View Abstract: The present invention provides compounds of the formula: … |
ELI LILLY | 2024-03-29 | 2024-10-17 | |
| 56 | THERAPEUTIC AGENT DELIVERY DEVICE Related Patents View Abstract: A therapeutic agent delivery device includes a disposable portion and a reusable portion that detachably carries the disposable portion. The reusable portion includes a drive … |
ELI LILLY | 2022-08-19 | 2024-10-17 | |
| 57 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS Related Patents View Abstract: In an embodiment, the present invention provides a compound of the formula: or a pharmaceutically acceptable salt thereof, and methods of using this compound for treating type II … |
ELI LILLY | 2022-05-19 | 2024-10-17 | |
| 58 | MEDICATION DELIVERY DEVICE WITH GEAR SET DOSAGE SYSTEM Related Patents View Abstract: A medication delivery device is disclosed including a rack-and-pinion plunger drive system. The drive system includes an output drive having a pawled end movably coupled with the … |
ELI LILLY | 2024-06-17 | 2024-10-10 | |
| 59 | METHODS OF USING AND COMPOSITIONS INCLUDING AN INCRETIN ANALOG Related Patents View Abstract: Doses and dosing regimens for incretin analogs are disclosed comprising determining and administering doses of long-acting incretin analogs suitable for once-weekly dosing, such … |
ELI LILLY | 2022-06-22 | 2024-10-03 | |
| 60 | NOVEL THERAPEUTIC DELIVERY MOIETIES AND USES THEREOF Related Patents View Abstract: The present invention relates to novel compounds comprising novel delivery moieties for delivery of oligonucleotides, which are useful in the treatment of disease, suitably … |
ELI LILLY | 2022-06-22 | 2024-10-03 | |
| 61 | METHODS OF PRODUCING FC-CONTAINING PROTEINS Related Patents View Abstract: Provided herein are improved methods for producing an Fc-containing protein. The methods generally involve culturing mammalian cells that produce the Fc-containing protein at a … |
ELI LILLY | 2024-03-21 | 2024-09-26 | |
| 62 | POLYMORPHS OF AN SSAO INHIBITOR Related Patents View Abstract: Provided herein are polymorphs of (2E)-3-fluoro-2-({[2-(4-methoxypiperidin-1-yl)pyrimidin-5 -yl]oxy} methyl)prop-2-en-1-aminium 4-methylbenzenesulfonate, compositions thereof, … |
ELI LILLY | 2024-05-28 | 2024-09-19 | |
| 63 | COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Related Patents View Abstract: The present disclosure relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated … |
ELI LILLY | 2024-04-05 | 2024-09-19 | |
| 64 | METHODS FOR THE PREPARATION AND DOSE REGIMENS FOR USE OF SSTR4 AGONISTS AND SALTS THEREOF Related Patents View Abstract: Method for preparing SSTR4 agonist compounds. Method for preparing SSTR4 agonist compounds through a diasteromerically selective cyclization reaction without the need for a … |
ELI LILLY | 2024-03-06 | 2024-09-19 | |
| 65 | USE OF MEVIDALEN AND OTHER D1 POSITIVE ALLOSTERIC MODULATORS IN THE TREATMENT OF HALLUCINATIONS AND DEMENTIA-RELATED PSYCHOSIS Related Patents View Abstract: The present invention relates to methods of treating and dosing regimens using Mevidalen, also described as … |
ELI LILLY | 2022-03-08 | 2024-09-12 | |
| 66 | CONNECTED INJECTION DEVICES WITH STATUS SENSING SYSTEMS Related Patents View Abstract: An injection device assembly including a housing, a syringe, a drive mechanism and one or more sensing systems are described. The drive mechanism advances the syringe from a … |
ELI LILLY | 2024-03-05 | 2024-08-29 | |
| 67 | MEDICATION DELIVERY DEVICE WITH DOSE BUTTON Related Patents View Abstract: Medication delivery devices are provided having a dose delivery button. A dose button includes a contact interface to enhance friction between a user’s finger when operating the … |
ELI LILLY | 2022-06-29 | 2024-08-29 | |
| 68 | PEPTIDES COMPRISING N-FORMYL-HALOGENATED METHIONINE RESIDUES AND ENGINEERED ANTIBODY-PEPTIDE CONJUGATES THEREOF Related Patents View Abstract: Peptides are provided that comprise an N-formyl methionine in which the methyl group of the side chain of methionine has been substituted with one or more halogens such as … |
ELI LILLY | 2022-06-07 | 2024-08-29 | |
| 69 | STATUS SENSING SYSTEM FOR INJECTION DEVICE Related Patents View Abstract: An injection device assembly including a housing, a syringe, a drive mechanism and a status sensing system and a module are described. The drive mechanism advances the syringe … |
ELI LILLY | 2024-02-19 | 2024-08-22 | |
| 70 | COMPOSITIONS OF EXTENDED RELEASE COATINGS AND METHODS FOR APPLYING EXTENDED RELEASE COATINGS Related Patents View Abstract: A polymer coating including therapeutic agent particles for use with an extended wear infusion catheter is disclosed. Such a coating mitigates inflammation at the catheter site … |
ELI LILLY | 2022-07-22 | 2024-08-22 | |
| 71 | METHODS FOR TREATING OBSTRUCTIVE SLEEP APNEA Related Patents View Abstract: The present invention relates to methods for treating, preventing or delaying disorders relating to obstructive sleep apnea. The present invention relates to methods for treating, … |
ELI LILLY | 2022-06-21 | 2024-08-22 | |
| 72 | GIP/GLP1/GCG TRI-RECEPTOR AGONISTS AND USES THEREOF Related Patents View Abstract: Polypeptides are provided that have activity at each of the GIP, GLP-1 and glucagon receptors. The polypeptides have structural features resulting in activity and extended … |
ELI LILLY | 2024-01-31 | 2024-08-15 | |
| 73 | METHOD FOR TREATING IDH INHIBITOR-RESISTANT SUBJECTS Related Patents View Abstract: The present invention relates to the treatment of human cancer subjects with mutant isocitrate dehydrogenase inhibitors disclosed herein. … |
ELI LILLY | 2022-06-09 | 2024-08-08 | |
| 74 | ANTI -IL-23P19 ANTIBODY REGULATION OF GENES INVOLVED IN ULCERATIVE COLITIS Related Patents View Abstract: The present disclosure generally relates to methods of treating and diagnosing ulcerative colitis. The methods are particularly suitable for treating and diagnosing a specific … |
ELI LILLY | 2022-05-27 | 2024-08-01 | |
| 75 | MEDICAL DELIVERY DEVICE WITH AXIALLY EXPANDABLE DRIVE RIBBON Related Patents View Abstract: A medication delivery device usable with a medication container wherein advancement of a piston within the container expels medication. The device includes a housing and a drive … |
ELI LILLY | 2024-04-01 | 2024-07-25 | |
| 76 | cGAS INHIBITORS Related Patents View Abstract: The present invention relates to novel cGAS inhibitor compounds, having a formula of: to pharmaceutical compositions comprising the compounds, and to methods of using the … |
ELI LILLY | 2023-12-20 | 2024-07-25 | |
| 77 | URI Agonist/Vasodilator Related Patents View Abstract: The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium … |
ELI LILLY | 2023-12-14 | 2024-07-18 | |
| 78 | GIP/GLP1 AGONIST COMPOSITIONS Related Patents View Abstract: A composition of tirzepatide, comprising an agent selected from NaCl and propylene glycol; and dibasic sodium phosphate is provided. … |
ELI LILLY | 2024-01-25 | 2024-07-11 | |
| 79 | GENE THERAPY FOR TREM2-ASSOCIATED DISEASES AND DISORDERS Related Patents View Abstract: Nucleic acids are described that encode for triggering receptor expressed on myeloid cells 2 (TREM2) and that can be used in expression constructs, vectors and gene therapies. … |
ELI LILLY | 2023-10-03 | 2024-07-11 | |
| 80 | VARIANT ADENO-ASSOCIATED VIRUS (AAV) CAPSID POLYPEPTIDES AND GENE THERAPEUTICS THEREOF FOR TREATMENT OF HEARING LOSS Related Patents View Abstract: Described herein are variant adeno-associated virus (AAV) capsid polypeptides and gene therapeutics thereof for use in the treatment or prevention of hearing loss. … |
ELI LILLY | 2023-05-05 | 2024-07-11 | |
| 81 | SUBSTITUTED FUSED AZINES AS KRAS G12D INHIBITORS Related Patents View Abstract: The present invention provides compounds of the formula where R , R , R , R , R , R , R , R , X, Y, and Z are as described herein, pharmaceutically acceptable salts thereof, and … |
ELI LILLY | 2022-06-08 | 2024-07-11 | |
| 82 | ERODIBLE TABLET Related Patents View Abstract: The present invention relates to an erodible tablet comprising a therapeutic peptide which is suitable for oral administration and, in addition, to a non-granulation process for … |
ELI LILLY | 2022-05-06 | 2024-07-11 | |
| 83 | METHODS OF TREATING CANCER WITH PDGFR ALPHA INHIBITORS Related Patents View Abstract: Methods for treating cancer patients with human platelet derived growth factor receptor alpha inhibiting compounds, in which the patient is identified as having a cancer that is … |
ELI LILLY | 2022-03-17 | 2024-07-11 | |
| 84 | SELF-ASPIRATING SYRINGE SYSTEMS, CARTRIDGES, AND METHODS Related Patents View Abstract: A cartridge is configured to receive an injectable drug. The cartridge includes a body, and the body includes a proximal end portion having a proximal opening, a distal end … |
ELI LILLY | 2022-02-24 | 2024-07-11 | |
| 85 | GIPR-AGONIST COMPOUNDS Related Patents View Abstract: The present invention relates to compounds having activity at the human glucose-dependent insulinotropic polypeptide (GIP) receptor. The present invention also relates to … |
ELI LILLY | 2023-12-20 | 2024-07-04 | |
| 86 | TASTE MASKED COMPOSTIONS OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND ORALLY DISENTEGRATING TABLET COMPRISING THE SAME Related Patents View Abstract: The present disclosure provides a novel palatable pharmaceutical composition in the form of taste-masked 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide … |
ELI LILLY | 2022-05-06 | 2024-07-04 | |
| 87 | PROTEIN TYROSINE-TYROSINE ANALOGS AND METHODS OF USING THE SAME Related Patents View Abstract: PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and … |
ELI LILLY | 2023-10-11 | 2024-06-27 | |
| 88 | 2019 NOVEL CORONAVIRUS ANTIBODY-CONTAINING PHARMACEUTICAL FORMULATIONS Related Patents View Abstract: A pharmaceutical formulation is provided that includes a 2019 novel coronavirus (2019-nCOV) antibody and agents that provide commercially acceptable shelf-life stability, in-use … |
ELI LILLY | 2022-06-08 | 2024-06-27 | |
| 89 | SYSTEMS AND METHODS FOR IGNITING PLASMA WITHIN TUBES Related Patents View Abstract: A system is provided for generating plasma within narrow diameter tubes, e.g., tubes with an inner diameter of less than 1 millimeter. The system may comprise the tube, a nozzle … |
ELI LILLY | 2022-05-11 | 2024-06-27 | |
| 90 | PROCESSES AND DEVICES FOR DELIVERY OF FLUID BY CHEMICAL REACTION Related Patents View Abstract: Processes and devices provide parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that … |
ELI LILLY | 2024-02-28 | 2024-06-20 | |
| 91 | DOSE DETECTION MODULE FOR A MEDICATION DELIVERY DEVICE Citation: 6 Related Patents View Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose … |
ELI LILLY | 2024-02-27 | 2024-06-20 | |
| 92 | PROCESSES FOR THE PREPARATION OF SELECTIVE ESTROGEN RECEPTOR DEGRADERS Related Patents View Abstract: Disclosed are methods of making selective estrogen receptor degraders (SERDs) of Formula A, as well as intermediates thereof, salts thereof including a pharmaceutically acceptable … |
ELI LILLY | 2024-01-31 | 2024-06-20 | |
| 93 | THERAPEUTIC USES OF DULAGLUTIDE Related Patents View Abstract: The present invention relates to methods of using dulaglutide for the treatment of chronic kidney disease in patients having moderate to late stage chronic kidney disease. … |
ELI LILLY | 2023-11-29 | 2024-06-20 | |
| 94 | AHR AGONISTS Related Patents View Abstract: The present disclosure relates to certain AHR agonist compounds, their method of making, and to pharmaceutical compositions comprising the compounds and to methods of using the … |
ELI LILLY | 2023-11-03 | 2024-06-20 | |
| 95 | FGFR3 INHIBITOR COMPOUNDS Related Patents View Abstract: The present invention provides compounds of the formula: for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia, thanatophoric … |
ELI LILLY | 2023-12-13 | 2024-06-13 | |
| 96 | Incretin Analogs and Uses Thereof Related Patents View Abstract: Incretin analogs are provided that have activity at each of the GIP. GLP-1 and glucagon receptors. The incretin analogs have structural features resulting in balanced activity and … |
ELI LILLY | 2023-10-30 | 2024-06-13 | |
| 97 | METHODS OF USING AND COMPOSITIONS CONTAINING DULAGLUTIDE Related Patents View Abstract: The present invention relates to methods of using new doses of dulaglutide and compositions containing such higher doses of dulaglutide … |
ELI LILLY | 2023-01-04 | 2024-06-13 | |
| 98 | TABLET DISPENSER Related Patents View Abstract: Tablet dispensers and methods for use are provided herein. In some embodiments, a tablet dispenser has a dosage actuator that permits a user to select a desired dosage to dispense … |
ELI LILLY | 2022-04-26 | 2024-06-06 | |
| 99 | LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF Related Patents View Abstract: The present invention relates to Atrial Natriuretic Peptide (ANP) polypeptides and methods of treatment with ANP polypeptides. … |
ELI LILLY | 2023-10-19 | 2024-05-30 | |
| 100 | HUMAN CD33 ANTIBODIES AND GLUCOCORTICOID CONJUGATES Related Patents View Abstract: The present disclosure provides human CD33 antibodies and antibody glucocorticoid receptor agonist conjugates and methods of using the conjugates for the treatment of myeloid cell … |
ELI LILLY | 2023-06-21 | 2024-05-30 | |
| 101 | INCRETIN ANALOG-CONTAINING COMPOSITIONS AND USES THEREOF Related Patents View Abstract: A composition is provided that includes an incretin analog having activity at each the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1) and … |
ELI LILLY | 2022-03-22 | 2024-05-30 | |
| 102 | LAG-3 AND PD-1/LAG-3-ANTIBODIES Related Patents View Abstract: The present disclosure relates to antibodies that bind to and agonize human LAG-3, and to bispecific antibodies that bind to and agonize each of human PD-1 and human LAG-3. … |
ELI LILLY | 2023-11-17 | 2024-05-23 | |
| 103 | MEDICAMENT CONTAINER Related Patents View Abstract: A medicament container including at least one sidewall and an extension is provided. The extension may be rigid in comparison to sidewalls that form the volume of the container. … |
ELI LILLY et. al. | 2022-04-27 | 2024-05-23 | |
| 104 | USE OF MEVIDALEN AND OTHER D1 POSITIVE ALLOSTERIC MODULATORS FOR SLOWING OF PARKINSON’S DISEASE PROGRESSION Related Patents View Abstract: The present invention relates to methods of treating and dosing regimens using Mevidalen, also described as … |
ELI LILLY | 2022-03-08 | 2024-05-23 | |
| 105 | GITR ANTAGONISTS AND METHODS OF USING THE SAME Related Patents View Abstract: The present disclosure relates to compounds that bind to human GITR, pharmaceutical compositions comprising such compounds, and methods of using such compounds. … |
ELI LILLY | 2023-12-07 | 2024-05-16 | |
| 106 | SYNTHETIC NUCLEIC ACIDS INCLUDING ASTROCYTE-DIRECTED PROMOTER CONSTRUCTS AND METHODS OF USING THE SAME Related Patents View Abstract: Synthetic nucleic acids are described that can be used for astrocyte-directed expression of heterologous nucleotide sequences. Also described are methods of using the same for … |
ELI LILLY | 2023-11-10 | 2024-05-16 | |
| 107 | ANTI-N3pGlu AMYLOID BETA ANTIBODIES AND USES THEREOF Related Patents View Abstract: Methods of treating, preventing and/or retarding the progression of cognitive decline, in human subjects having a disease characterized by deposition of Aβ in the brain including … |
ELI LILLY | 2022-03-11 | 2024-05-16 | |
| 108 | TREATMENT OF ANDROGEN DEPRIVATION THERAPY ASSOCIATED SYMPTOMS Related Patents View Abstract: The present invention provides a method of treating symptoms associated with Androgen Deprivation Therapy comprising administering to a patient in need of such treatment an … |
ELI LILLY | 2023-12-12 | 2024-05-09 | |
| 109 | ANTI-AMYLOID BETA ANTIBODIES AND USES THEREOF Related Patents View Abstract: The invention is directed to treatment or prevention of a disease characterized by deposition of Aβ in the brain using anti-Aβ antibodies. The diseases that can be treated or … |
ELI LILLY | 2022-03-11 | 2024-05-09 | |
| 110 | THERAPEUTIC USES OF DULAGLUTIDE Related Patents View Abstract: The present invention relates to methods for reducing the risk of major adverse cardiovascular events in type 2 diabetes mellitus (T2DM) patients with multiple cardiovascular risk … |
ELI LILLY | 2024-01-10 | 2024-05-02 | |
| 111 | COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Related Patents View Abstract: The present invention relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated … |
ELI LILLY | 2023-04-07 | 2024-05-02 | |
| 112 | LASOFOXIFENE COMBINATION TREATMENT OF ER+ BREAST CANCER THAT HAS PROGRESSED ON A CDK4/6 INHIBITOR Related Patents View Abstract: Methods for reducing the progression of ER+breast cancer in a patient are provided, the methods comprising administering to the patient an effective amount of lasofoxifene or a … |
SERMONIX PHARMACEUTICALS et. al. | 2023-12-05 | 2024-04-18 | |
| 113 | COCRYSTALLINE FORMS OF FGFR3 INHIBITORS Related Patents View Abstract: Provided herein are cocrystalline forms of FGFR3 inhibitors and gallic acid or nicotinamide coformers useful in the treatment and prevention of diseases which can be treated with … |
ELI LILLY | 2023-09-06 | 2024-04-11 | |
| 114 | COMPOSITIONS AND METHODS OF USE OF INTERLEUKIN-10 IN COMBINATION WITH IMMUNE CHECK-POINT PATHWAY INHIBITORS Related Patents View Abstract: The present disclosure provides a method for the treatment of neoplastic disease in a mammalian subject the method comprising the administration of an IL-10 agent in combination … |
ELI LILLY | 2023-10-17 | 2024-04-04 | |
| 115 | KRAS G12C INHIBITOR DOSING REGIMENS Related Patents View Abstract: Disclosed herein are dosing regimens for the administration of a compound of Formula I: … |
ELI LILLY | 2023-06-29 | 2024-04-04 | |
| 116 | ANTI-HUMAN LAIR1 ANTIBODIES Related Patents View Abstract: The present disclosure relates to antibodies that bind human LAIR1 (“anti-human LAIR1 antibodies” or “anti-human LAIR1 antibodies”), compositions comprising such anti-human LAIR1 … |
ELI LILLY et. al. | 2023-09-15 | 2024-03-28 | |
| 117 | HUMAN INTERLEUKIN-4 RECEPTOR ALPHA ANTIBODY GLUCOCORTICOID CONJUGATES Related Patents View Abstract: The present disclosure provides human interleukin 4 receptor alpha antibody glucocorticoid receptor agonist conjugates and methods of using the conjugates for the treatment of … |
ELI LILLY | 2023-05-31 | 2024-03-28 | |
| 118 | METHODS AND APPARATUS FOR INCREMENTAL LEARNING USING STORED FEATURES Related Patents View Abstract: Computerized techniques are provided for storing a set of representative features for use with a machine learning process. A first set of training images for a class are accessed … |
ELI LILLY | 2022-02-18 | 2024-03-28 | |
| 119 | MEDICATION DELIVERY DEVICE INCLUDING DISPOSABLE AND REUSABLE PORTIONS Related Patents View Abstract: A medication delivery device includes a disposable portion and a reusable portion. The disposable portion includes a therapeutic agent delivery assembly, and the therapeutic agent … |
ELI LILLY | 2023-11-17 | 2024-03-21 | |
| 120 | MEDICATION DELIVERY DEVICE WITH A SENSED ELEMENT Related Patents View Abstract: A medication delivery device including a device body and a dose setting component coupled to the device body. Component is rotatable relative to the device body in relation to an … |
ELI LILLY | 2023-11-15 | 2024-03-14 | |
| 121 | HUMAN TUMOR NECROSIS FACTOR ALPHA ANTIBODY GLUCOCORTICOID CONJUGATES Related Patents View Abstract: The present disclosure provides human tumor necrosis factor alpha antibody glucocorticoid receptor agonist conjugates and methods of using the conjugates for the treatment of … |
ELI LILLY | 2023-05-05 | 2024-03-14 | |
| 122 | SSTR4 AGONIST SALTS Related Patents View Abstract: The present invention relates to specific salts of (1S,5R)-(1α,5α,6α)-N-[1,1-dimethyl-2-[(3-methyl-2-pyridyl)oxy]ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide, to pharmaceutical … |
ELI LILLY | 2023-08-07 | 2024-02-29 | |
| 123 | PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACETATE Related Patents View Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of … |
ELI LILLY | 2023-10-18 | 2024-02-22 | |
| 124 | TRANSFERRIN RECEPTOR BINDING PROTEINS AND CONJUGATES Related Patents View Abstract: Provided herein are proteins comprising one monovalent human TfR binding domain (“human TfR binding proteins”), proteins comprising one monovalent mouse TfR binding domain (“mouse … |
ELI LILLY | 2023-08-07 | 2024-02-22 | |
| 125 | Methods for Producing Fabs and IgG Bispecific Antibodies Related Patents View Abstract: Methods for producing Fabs and IgG bi-specific antibodies comprising expressing nucleic acids encoding designed residues in the CH1/CL interface are provided. Also provided are … |
ELI LILLY et. al. | 2023-10-10 | 2024-02-08 | |
| 126 | KRAS INHIBITORS Related Patents View Abstract: The present invention provides compounds of the formula: … |
ELI LILLY | 2023-03-24 | 2024-02-08 | |
| 127 | TECHNIQUES FOR PROCESSING WIRELESSLY BROADCAST PACKETS FROM A MEDICAL DEVICE WITH DOSE-RELATED DATA Related Patents View Abstract: A computing device is provided having a processor in communication with a memory configured to store machine-readable instructions. The processor can receive, from a wireless … |
ELI LILLY | 2022-07-27 | 2024-02-01 | |
| 128 | GLUCOCORTICOID RECEPTOR AGONISTS Related Patents View Abstract: The present invention provides a compound of Formula I: wherein R is H or … |
ELI LILLY | 2023-09-08 | 2024-01-18 | |
| 129 | cGAS INHIBITORS Related Patents View Abstract: The present invention relates to novel cGAS inhibitor compounds, to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to … |
ELI LILLY | 2023-06-01 | 2023-12-07 | |
| 130 | LASOFOXIFENE COMBINATION TREATMENT OF ER+ BREAST CANCER THAT HAS PROGRESSED ON A CDK4/6 INHIBITOR Related Patents View Abstract: Methods for reducing the progression of ER+ breast cancer in a patient are provided, the methods comprising administering to the patient an effective amount of lasofoxifene or a … |
SERMONIX PHARMACEUTICALS et. al. | 2023-05-25 | 2023-11-30 | |
| 131 | SECURED MEDICATION TRANSFER SYSTEM Related Patents View Abstract: A vial adaptor and needle assembly are disclosed for use with a vial containing a medication, such as insulin. The vial adaptor may include a needle opening configured to receive … |
ELI LILLY | 2023-08-02 | 2023-11-23 | |
| 132 | AT2R ANTAGONISTS AND USES THEREOF Related Patents View Abstract: This invention provides certain piperidine compounds as AT R antagonists, e.g., compounds of formula (I): … |
ELI LILLY | 2023-05-11 | 2023-11-23 | |
| 133 | PHENYL-2-HYDROXY-ACETYLAMINO-2-METHYL-PHENYL COMPOUNDS FOR THE TREATMENT OF PANCREATIC CANCER Related Patents View Abstract: The present invention provides phenyl-2-hydroxy-acetylamino-2-methyl-phenyl compounds, to pharmaceutical compositions comprising the compounds, to methods of using the compounds … |
ELI LILLY | 2023-04-13 | 2023-11-23 | |
| 134 | KRAS Gl2C INHIBITORS Related Patents View Abstract: The present invention provides compounds of the formula: where R , R , R , R , R , A, B, and Y are as described herein, pharmaceutically acceptable salts thereof, and methods of … |
ELI LILLY | 2023-06-28 | 2023-10-26 | |
| 135 | OSCILLATING FLUIDIZED BED OLIGONUCLEOTIDE SYNTHESIZER Related Patents View Abstract: A method and device for building an oligonucleotide on a solid phase resin within a filter reactor, wherein the method and device as used as a solid phase synthesis system. As … |
ELI LILLY | 2023-05-15 | 2023-10-26 | |
| 136 | MAPT RNA INTERFERENCE AGENTS Related Patents View Abstract: Provided herein are MAPT RNAi agents and compositions comprising a MAPT RNAi agent. Also provided herein are methods of using the MAPT RNAi agents or compositions comprising a … |
ELI LILLY | 2023-05-03 | 2023-10-26 | |
| 137 | COMPOUNDS USEFUL FOR INHIBITING RET KINASE Related Patents View Abstract: Provided herein are RET kinase inhibitors according to the formula: … |
ELI LILLY | 2023-02-06 | 2023-10-05 | |
| 138 | NASAL DELIVERY DEVICE Related Patents View Abstract: The present disclosure provides a nasal delivery device with a device body that includes a trigger end and an outlet end. The nasal delivery device also includes a trigger … |
ELI LILLY | 2023-05-17 | 2023-09-28 | |
| 139 | NASAL POWDER FORMULATION FOR TREATMENT OF HYPOGLYCEMIA Related Patents View Abstract: The present invention provides a powder formulation containing glucagon or a glucagon analog for nasal administration, useful in the treatment of hypoglycemia, and in particular … |
ELI LILLY | 2023-02-10 | 2023-09-28 | |
| 140 | Treatment of Respiratory Disease Related Patents View Abstract: Methods of preventing and/or treating ARDS with anti-IL17 antibodies, including dose regimens and pharmaceutical formulations of anti-IL17 antibodies for use in the prevention … |
ELI LILLY | 2022-09-26 | 2023-09-21 | |
| 141 | METHODS AND SYSTEMS FOR SELECTING AN INJECTION SITE Related Patents View Abstract: Methods and systems are provided for evaluating injection sites on a body of a patient. The methods/systems may instruct a patient to place one or more capacitance sensors in … |
ELI LILLY | 2022-07-14 | 2023-09-21 | |
| 142 | COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Related Patents View Abstract: The present invention relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated … |
ELI LILLY | 2023-04-07 | 2023-09-07 | |
| 143 | ANTI-CD137 ANTIBODIES Related Patents View Abstract: The present invention relates to antibodies that bind to human CD137 and display agonist activity, and may be useful for treating solid and hematological tumors alone and in … |
ELI LILLY | 2022-11-01 | 2023-09-07 | |
| 144 | COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Related Patents View Abstract: The present disclosure relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated … |
ELI LILLY | 2022-10-27 | 2023-09-07 | |
| 145 | RET KINASE INHIBITORS Related Patents View Abstract: Disclosed herein are compounds of formula I: or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET … |
ELI LILLY | 2022-10-19 | 2023-08-24 | |
| 146 | DRIVE RIBBON FOR MOVING PISTON WITHIN CONTAINER Related Patents View Abstract: A medical delivery device for advancing a piston in a medicament container to expel a medicament. A support structure supports the container and a drive assembly that advances the … |
ELI LILLY | 2023-04-25 | 2023-08-17 | |
| 147 | DRUG DELIVERY DEVICE CASSETTE Related Patents View Abstract: A drug delivery device may include a cassette with a needle assembly and a cartridge. The cassette is configured to couple and decouple from a reusable module. The device may also … |
ELI LILLY | 2022-08-19 | 2023-08-17 | |
| 148 | PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACETATE Related Patents View Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of … |
ELI LILLY | 2023-04-14 | 2023-08-10 | |
| 149 | PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACETATE Related Patents View Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of … |
ELI LILLY | 2023-04-14 | 2023-08-10 | |
| 150 | GLUCAGON-LIKE PEPTIDE1 RECEPTOR AGONISTS Related Patents View Abstract: In an embodiment, the present invention provides a compound of the formula: or a pharmaceutically acceptable salt thereof, and methods of using this compound for treating type II … |
ELI LILLY | 2023-03-31 | 2023-08-10 | |
| 151 | PROCESSES FOR THE PREPARATION OF SELECTIVE ESTROGEN RECEPTOR DEGRADERS Related Patents View Abstract: Disclosed are methods of making selective estrogen receptor degraders (SERDs) of Formula A, as well as intermediates thereof, salts thereof including a pharmaceutically acceptable … |
ELI LILLY | 2023-01-27 | 2023-08-03 | |
| 152 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS Related Patents View Abstract: Novel selective estrogen receptor degraders (SERDs) according to the formula: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R … |
ELI LILLY | 2023-03-15 | 2023-07-27 | |
| 153 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS Related Patents View Abstract: The present invention provides a compound of Formula I: … |
ELI LILLY | 2023-02-28 | 2023-07-20 | |
| 154 | COMPOUNDS AND METHODS TARGETING INTERLEUKIN-19 Related Patents View Abstract: The present invention provides compounds and methods targeting human interleukin-19, including therapeutic antibodies, pharmaceutical compositions and diagnostic applications … |
ELI LILLY | 2023-01-25 | 2023-07-13 | |
| 155 | MAPT RNA INTERFERENCE AGENTS Related Patents View Abstract: Provided herein are MAPT RNAi agents and compositions comprising a MAPT RNAi agent. Also provided herein are methods of using the MAPT RNAi agents or compositions comprising a … |
ELI LILLY | 2022-12-12 | 2023-07-06 | |
| 156 | Incretin Analogs and Uses Thereof Related Patents View Abstract: Incretin analogs are provided that have activity at each of the GIP, GLP-1 and glucagon receptors. The incretin analogs have structural features resulting in balanced activity and … |
ELI LILLY | 2022-11-21 | 2023-06-29 | |
| 157 | HUMAN TUMOR NECROSIS FACTOR ALPHA ANTIBODIES Related Patents View Abstract: The present disclosure relates to antibodies that specifically bind soluble and membrane forms of human TNFα, compositions comprising such TNFα antibodies, and methods of using … |
ELI LILLY | 2022-11-10 | 2023-06-22 | |
| 158 | DUAL AMYLIN AND CALCITONIN RECEPTOR AGONISTS AND USES THEREOF Related Patents View Abstract: The present disclosure related to the field of medicine. More particularly, the disclosure is in the field of treatment of diabetes, obesity, and/or dyslipidemia. The disclosure … |
ELI LILLY | 2022-10-28 | 2023-06-22 | |
| 159 | DUAL AMYLIN AND CALCITONIN RECEPTOR AGONISTS AND USES THEREOF Related Patents View Abstract: The present disclosure related to the field of medicine. More particularly, the disclosure is in the field of treatment of diabetes, obesity, and/or dyslipidemia. The disclosure … |
ELI LILLY | 2022-10-28 | 2023-06-22 | |
| 160 | THERAPEUTIC ANTIBODY FORMULATION Related Patents View Abstract: Stable aqueous pharmaceutical formulations for therapeutic antibodies and methods of using such stable aqueous pharmaceutical formulations. … |
ELI LILLY | 2023-03-01 | 2023-06-15 | |
| 161 | DOSE DETECTION MODULE FOR A MEDICATION DELIVERY DEVICE Related Patents View Abstract: The present disclosure relates to a dose detection system and method for a medication delivery device. The dose detection system may include a dosing component attached to an … |
ELI LILLY | 2022-12-15 | 2023-06-15 | |
| 162 | DOSE DETECTION WITH PIEZOELECTRIC SENSING FOR A MEDICATION DELIVERY DEVICE Related Patents View Abstract: The present disclosure relates to a medication delivery device having a dose detection system and an associated control system configured to determine an amount of medication … |
ELI LILLY | 2023-02-07 | 2023-06-08 | |
| 163 | PHARMACEUTICAL PREPARATION FOR IMPROVING ABSORPTION AND POSTPRANDIAL HYPOGLYCEMIC ACTION OF INSULIN Related Patents View Abstract: The present disclosure relates to compositions and combinations comprising one or more insulin(s) and one or more vasoactive agent(s), and use thereof for increasing subcutaneous … |
ELI LILLY | 2023-01-19 | 2023-05-25 | |
| 164 | AHR AGONISTS Related Patents View Abstract: The present invention relates to certain substituted AHR agonist compounds, to pharmaceutical compositions comprising the compounds and to methods of using the compounds to treat … |
ELI LILLY | 2022-09-13 | 2023-05-25 | |
| 165 | Anti-CGRP Antibody Formulation Related Patents View Abstract: Pharmaceutical formulations for anti-CGRP antibodies, and methods of using the same, are provided which are useful as treatment for migraines, episodic headaches, chronic … |
ELI LILLY | 2022-08-08 | 2023-05-25 | |
| 166 | AHR AGONISTS Related Patents View Abstract: The present invention relates to certain substituted AHR agonist compounds, to pharmaceutical compositions comprising the compounds and to methods of using the compounds to treat … |
ELI LILLY | 2022-09-13 | 2023-04-27 | |
| 167 | DOSE DETECTION AND DRUG IDENTIFICATION FOR A MEDICATION DELIVERY DEVICE Related Patents View Abstract: The present disclosure relates to a dose detection system for use in combination with a medication delivery device. In one aspect, the system includes a module keyed to the device … |
ELI LILLY | 2022-12-20 | 2023-04-20 | |
| 168 | DOSE DETECTION MODULE FOR A MEDICATION DELIVERY DEVICE Related Patents View Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose … |
ELI LILLY | 2022-12-13 | 2023-04-13 | |
| 169 | SSTR4 AGONIST SALTS Related Patents View Abstract: The present invention relates to specific salts of (1S,5R)-(1α,5α,6α)-N-[1,1-dimethyl-2-[(3-methyl-2-pyridyl)oxy]ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide, to pharmaceutical … |
ELI LILLY | 2022-09-14 | 2023-03-30 | |
| 170 | FGFR3 INHIBITOR COMPOUNDS Related Patents View Abstract: The present invention provides compounds of the formula: for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia, thanatophoric … |
ELI LILLY | 2022-03-03 | 2023-03-30 | |
| 171 | Gripping Attachment for a Bottle Related Patents View Abstract: A gripping attachment ( ) is disclosed which facilitates the handling of a medication bottle ( ). The medication bottle includes a container ( ) having a cylindrical wall ( ) … |
ELI LILLY | 2022-11-23 | 2023-03-16 | |
| 172 | SOLID FORMS OF 7-[[(1S)-1-[4-[(1S)-2-CYCLOPROPYL-1-(4-PROP-2-ENOYLPIPERAZIN-1-YL)ETHYL]PHENYL]ETHYL]AMINO]-1-ETHYL-4H-PYRIMIDO[4,5-D][1,3]OXAZIN-2-ONE Related Patents View Abstract: Solid forms including 7-[[(1S)-1-[4-[(1S)-2-cyclopropyl-1-(4-prop-2-enoylpiperazin-1-yl)ethyl]phenyl]ethyl]amino]-1-ethyl-4H-pyrimido[4,5-d][1,3]oxazin-2-one and a … |
ELI LILLY | 2022-08-12 | 2023-03-02 | |
| 173 | HUMAN INTERLEUKIN-4 RECEPTOR ALPHA ANTIBODIES Related Patents View Abstract: The present disclosure relates to antibodies that specifically bind human IL-4Rα, compositions comprising such IL-4Rα antibodies, and methods of using such IL-4Rα antibodies. … |
ELI LILLY | 2022-08-05 | 2023-03-02 | |
| 174 | NOVEL RNA THERAPEUTICS AND USES THEREOF Related Patents View Abstract: The present disclosure relates to novel RNAi agents designed to decrease the expression of ANGPTL8 in the liver, where the RNAi agents comprise delivery moieties conjugated to … |
ELI LILLY | 2022-06-22 | 2023-01-26 | |
| 175 | MEDICATION DELIVERY DEVICE Related Patents View Abstract: The present disclosure relates to a dose detection system for use in combination with a medication delivery device in which a dose setting member rotates relative to an actuator … |
ELI LILLY | 2022-09-19 | 2023-01-19 | |
| 176 | MEDICATION DELIVERY DEVICE WITH ROTATION SENSOR Citation: 1 Related Patents View Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose … |
ELI LILLY | 2022-09-12 | 2023-01-05 | |
| 177 | NEEDLE SHIELD PULLER FOR DRUG DELIVERY SYSTEM Related Patents View Abstract: A device for removing a protective shield such as a needle shield is disclosed. The device includes a cup shaped body with a sidewall, a distal bottom wall and a proximal opening. … |
ELI LILLY | 2022-09-02 | 2022-12-29 | |
| 178 | MEDICATION DELIVERY DEVICE WITH SENSING SYSTEM Related Patents View Abstract: Medication delivery devices are provided having a dose delivery sensing capability. A sensed element is attached to a dose setting member of the device. The sensed element … |
ELI LILLY | 2022-08-04 | 2022-11-24 | |
| 179 | (TRIFLUOROMETHYL)PYRIMIDINE-2-AMINE COMPOUNDS Related Patents View Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, useful for treating pain, including chronic pain, chronic lower back pain, … |
ELI LILLY | 2022-07-25 | 2022-11-24 | |
| 180 | COMPOUNDS AND METHODS TARGETING EPIREGULIN Related Patents View Abstract: The present invention relates to epiregulin antibodies, compositions comprising the same, and methods of making and/or using the antibodies and/or compositions thereof for chronic … |
ELI LILLY | 2022-05-19 | 2022-11-24 | |
| 181 | MEDICATION DELIVERY DEVICE WITH SENSING SYSTEM Related Patents View Abstract: Medication delivery devices are provided having a dose delivery sensing capability. A sensed element is attached to a dose setting member of the device. The sensed element … |
ELI LILLY | 2022-07-29 | 2022-11-17 | |
| 182 | GLUCOCORTICOID RECEPTOR AGONISTS Related Patents View Abstract: The present invention provides a compound of Formula I: wherein R is H or R is H, halogen, C1-C3 alkyl, C3-C6 cycloalkyl, C1-C3 alkoxy, C2-C3 alkenyl, OCF , R is H, halogen, C1-C3 … |
ELI LILLY | 2022-03-22 | 2022-10-13 | |
| 183 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS Related Patents View Abstract: The present invention provides a compound of Formula I: wherein R is H, halogen, C1-C3 alkyl, or C1-C3 alkoxy; R is H or halogen; and X is O, OCH , or CH , or a pharmaceutically … |
ELI LILLY | 2022-03-22 | 2022-09-29 | |
| 184 | GLUCOCORTICOID RECEPTOR AGONISTS Related Patents View Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen, —P(═O)(OH) , or a pharmaceutically acceptable salt thereof, wherein the compound of Formula I, or … |
ELI LILLY | 2022-03-22 | 2022-09-29 | |
| 185 | DOSE SENSING MECHANISM IN A MEDICATION DELIVERY DEVICE Related Patents View Abstract: Medication delivery devices, sensing systems, and methods are disclosed for determining the relative axial and rotational movements of its members to determine the amount of a … |
ELI LILLY | 2022-06-10 | 2022-09-22 | |
| 186 | TARGETED TREATMENT OF MATURE T-CELL LYMPHOMA Citation: 2 Related Patents View Abstract: A method and medicament comprising 4,4,4-trifluoro-N-[(IS)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]butanamide or a … |
ELI LILLY | 2022-06-02 | 2022-09-22 | |
| 187 | METHODS FOR VIRAL INACTIVATION BY ENVIRONMENTALLY COMPATIBLE DETERGENTS Related Patents View Abstract: The invention provides methods of using environmentally compatible detergents in the field of recombinant protein manufacturing for inactivating viruses in a product feedstream in … |
ELI LILLY | 2022-06-02 | 2022-09-22 | |
| 188 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS Related Patents View Abstract: Novel selective estrogen receptor degraders (SERDs) according to the formula: and pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof, wherein R is … |
ELI LILLY | 2022-03-10 | 2022-09-22 | |
| 189 | MEDICATION DELIVERY DEVICE WITH SENSING SYSTEM Citation: 1 Related Patents View Abstract: Medication delivery devices are provided having a dose delivery sensing capability. A sensed element is attached to a dose setting member of the device. The sensed element … |
ELI LILLY | 2022-06-03 | 2022-09-15 | |
| 190 | PHARMACEUTICAL COMPOSITIONS Related Patents View Abstract: The present invention relates to solid oral fixed dose compositions of metformin, atorvastatin, and valsartan, or their pharmaceutically acceptable salts, processes for the … |
ELI LILLY | 2022-06-01 | 2022-09-15 | |
| 191 | Methods of treating cancer using a combination of SERD Dosing Regimens Related Patents View Abstract: Disclosed herein are dosing regimens for the administration of a compound of Formula I: or pharmaceutically acceptable salt thereof to patients in need of such treatment. The … |
ELI LILLY | 2022-03-08 | 2022-09-15 | |
| 192 | LONG ACTING AMYLIN RECEPTOR AGONISTS AND USES THEREOF Citation: 1 Related Patents View Abstract: The present disclosure relates to the field of medicine. More particularly, the disclosure is in the field of treatment of diabetes, obesity and/or chronic weight management, … |
ELI LILLY | 2022-03-02 | 2022-09-15 | |
| 193 | LYSOPHOSPHATIDIC ACID RECEPTOR 1 (LPAR1) INHIBITOR COMPOUNDS Related Patents View Abstract: The present invention provides a compound of formula or a pharmaceutical salt thereof, use, methods for its preparation are described. … |
ELI LILLY | 2022-05-18 | 2022-09-08 | |
| 194 | TREM2 ANTIBODIES AND USES THEREOF Related Patents View Abstract: The present invention relates to TREM2 antibodies, and uses thereof, for treating diseases such as neurodegenerative diseases. … |
ELI LILLY | 2022-05-05 | 2022-09-08 | |
| 195 | Treatment of Genital Psoriasis Related Patents View Abstract: Methods of treating genital psoriasis, genital pruritus and genital psoriasis sexual activity impairment with anti-IL17A antibodies, including dose regimens and pharmaceutical … |
ELI LILLY | 2022-05-13 | 2022-09-01 | |
| 196 | GIP/GLP1 AGONIST COMPOSITIONS Citation: 1 Related Patents View Abstract: A composition of tirzepatide, comprising an agent selected from NaCl and propylene glycol; and dibasic sodium phosphate is provided. … |
ELI LILLY | 2022-05-10 | 2022-09-01 | |
| 197 | CD200R AGONIST ANTIBODIES AND USES THEREOF Related Patents View Abstract: The present invention relates to anti-human CD200R agonist antibodies, and uses thereof for treating diseases such as atopic dermatitis, chronic spontaneous urticaria, allergy, … |
ELI LILLY | 2022-04-21 | 2022-08-11 | |
| 198 | RECOMBINANTLY ENGINEERED, LIPASE/ESTERASE-DEFICIENT MAMMALIAN CELL LINES Related Patents View Abstract: Mammalian cell lines with reduced expression and/or activity of lipases/esterases, and methods of producing the same are provided. Also provided are compositions comprising … |
ELI LILLY | 2022-04-14 | 2022-08-11 | |
| 199 | ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF Related Patents View Abstract: The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer’s … |
ELI LILLY | 2022-04-01 | 2022-07-28 | |
| 200 | MEDICATION INJECTION SYSTEM Related Patents View Abstract: An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier may include two identical parts that are … |
ELI LILLY | 2022-03-25 | 2022-07-07 |