Clinical Digest: A Comprehensive Review of Recent Pfizer Patents (2026-04)
This compilation provides an overview of Pfizer‘s latest patent inventions. Alongside these patents are potentially related patents, which may include work from Pfizer or other entities exploring similar therapeutic areas. This resource aims to offer researchers, clinicians, investors, and the broader public insights into Pfizer’s current research and development pipeline. By presenting patent details alongside related intellectual property (regardless of origin), this compilation facilitates a broader understanding of Pfizer’s strategic focus and how it potentially compares to direct and indirect competitors in these therapeutic spaces. This information can be valuable for identifying emerging trends in drug development, assessing the commercial potential of specific research programs, and understanding the broader landscape of scientific contributions related to Pfizer’s patent inventions. (Last updated on: 2026-04-05)
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TABLE 1: Clinical Digest: A Comprehensive Review of Recent Pfizer Patents (2026-04)
| Title | Applicant/Assignee | Filing Date | Publish Date | Grant Date | |
|---|---|---|---|---|---|
| 1 | ANTI-TL1A ANTIBODY THERAPEUTIC METHODS Related Patents View Abstract: The present disclosure provides methods and compositions for determining the risk of a patient being non-responsive to a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) … |
GENENTECH et. al. | 2025-11-14 | 2026-03-19 | |
| 2 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2025-05-02 | 2026-03-19 | |
| 3 | HYBRID SENSOR NETWORK IN AUTOCLAVING OF PRE-FILLED VIALS Related Patents View Abstract: Method and system of packaging a pre-filled vial. The method includes simulating, in a processor of a computing system based at least in part on a simulation model that includes a … |
PFIZER | 2025-09-09 | 2026-03-12 | |
| 4 | COMPUTERIZED DECISION TOOL FOR SARS-COV-2 VARIANTS PREDICTION Related Patents View Abstract: Technology is disclosed for a method for screening genetic mutations that can be used to predict vaccine composition, the method may include selecting a plurality of genome … |
PFIZER | 2023-08-17 | 2026-03-12 | |
| 5 | Benzisoxazole Sulfonamide Derivatives Related Patents View Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ring A, R -R , and n are defined herein. The novel benzisoxazole … |
PFIZER et. al. | 2025-06-18 | 2026-03-05 | |
| 6 | POLYNUCLEOTIDE COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The invention relates to polypeptides and RNA molecules encoding an fimbrial antigen PapG mutant. The present disclosure further relates to compositions comprising the RNA … |
PFIZER | 2025-03-21 | 2026-03-05 | |
| 7 | IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS, KITS COMPRISING THE SAME AND USES THEREOF Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions … |
PFIZER | 2025-01-15 | 2026-03-05 | |
| 8 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF Related Patents View Abstract: Described herein are compounds of Formula I: and their pharmaceutically acceptable salts, wherein R , R , R , R , L , L , T , T , T , T , n1, t1, t2, and t3 are defined herein; … |
PFIZER | 2025-08-20 | 2026-02-26 | |
| 9 | IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS, KITS COMPRISING THE SAME AND USES THEREOF Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions … |
PFIZER | 2025-06-17 | 2026-02-19 | |
| 10 | HEALTH INFORMATION NETWORK WELLNESS PLATFORM Related Patents View Abstract: A system and method for personalizing health information content provided to a user. The techniques include obtaining user profile data associated with the user in response to a … |
PFIZER | 2025-08-08 | 2026-02-12 | |
| 11 | Biphenyl and Phenylpyridine Compounds Related Patents View Abstract: The invention relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their … |
PFIZER | 2025-07-31 | 2026-01-29 | |
| 12 | IMMUNOGENIC COMPOSITIONS FOR USE IN PNEUMOCOCCAL VACCINES Related Patents View Abstract: An object of the present invention is to provide immunogenic compositions for protection against , in particular against serogroup 18, while limiting the number of conjugates. … |
PFIZER | 2025-04-28 | 2026-01-29 | |
| 13 | DOSING REGIMENS COMPRISING A KAT6 INHIBITOR FOR THE TREATMENT OF CANCER Related Patents View Abstract: The invention relates to dosing regimens for the treatment of cancer comprising administering to a subject in need thereof a daily dose of a lysine acetyltransferase 6 (KAT6) … |
PFIZER et. al. | 2023-07-25 | 2026-01-29 | |
| 14 | Methods And Intermediates for Preparing 2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S)-oxetan-2-ylmethyl]-1H-benzimidazole-6-carboxylic acid, 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine Salt Related Patents View Abstract: The invention provides methods and certain intermediates for preparing … |
PFIZER | 2023-07-19 | 2026-01-29 | |
| 15 | IMMUNOGENIC COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The present disclosure relates to RSV F, hMPV F, PIV3 F, PIV3 HN, PIV1 F and PIV1 HN protein mutants, nucleic acids or vectors encoding them, compositions comprising a RSV F, hMPV … |
PFIZER | 2025-07-16 | 2026-01-22 | |
| 16 | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof Related Patents View Abstract: The present invention relates to new conjugated capsular saccharide antigens (glycoconjugates), immunogenic compositions comprising said glycoconjugates and uses thereof. … |
PFIZER | 2025-03-05 | 2026-01-15 | |
| 17 | MEDIA AND FERMENTATION METHODS FOR PRODUCING POLYSACCHARIDES IN BACTERIAL CELL CULTURE Related Patents View Abstract: The present invention relates to media and fermentation methods for producing polysaccharides in bacterial cell culture. In one aspect, the invention relates to a complex culture … |
PFIZER | 2025-09-16 | 2026-01-08 | |
| 18 | USE OF A SPRAY FREEZE-DRYING PROCESS FOR THE LYOPHILIZATION OF A mRNA-ENCAPSULATING LIPID NANOPARTICLES FORMULATION Related Patents View Abstract: The invention relates to the lyophilization of a liquid pharmaceutical formulation including lipid nanoparticles encapsulating mRNA. According to the invention, a spray … |
PFIZER | 2023-06-20 | 2026-01-08 | |
| 19 | COAXIAL FLOW DEVICE FOR NANOPARTICLE PREPARATION AND MANUFACTURING EQUIPMENT INCLUDING SUCH DEVICE Related Patents View Abstract: The invention relates to a coaxial flow device capable of creating comparable microenvironments at various operation scales through the continuous introduction and mixing of … |
PFIZER | 2023-09-12 | 2025-12-25 | |
| 20 | Immunogenic Compositions Comprising Conjugated Capsular Saccharide Antigens and Uses Thereof Related Patents View Abstract: The present invention relates to new conjugated capsular saccharide antigens (glycoconjugates), immunogenic compositions comprising said glycoconjugates and uses thereof. … |
PFIZER | 2023-01-10 | 2025-12-18 | |
| 21 | METHODS FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE WITH AN ANTI-TL1A ANTIBODY Related Patents View Abstract: The present disclosure provides methods and compositions for treating inflammatory bowel disease (IBD), e.g., ulcerative colitis (UC) or Crohn’s disease (CD), with a therapeutic … |
GENENTECH et. al. | 2025-05-16 | 2025-12-11 | |
| 22 | Lipid Compounds and Uses Thereof Related Patents View Abstract: Compounds are provided having the following structure: (I) or a pharmaceutically acceptable salt, N-oxide, tautomer or stereoisomer thereof, wherein R , G , W and m, n, o and p … |
PFIZER | 2023-11-01 | 2025-12-04 | |
| 23 | SYSTEMS AND METHODS FOR PERFORMING BIOLOGICAL ASSAYS USING A THERMALLY SEALED VALVE Related Patents View Abstract: Provided herein are systems and methods for performing biological assays using a thermally sealed valve and/or incubation chamber. The systems and methods determine one or more … |
PFIZER | 2023-06-12 | 2025-12-04 | |
| 24 | Enhancement Of CD47 Blockade Therapy With Anti-VEGF Agents Related Patents View Abstract: Various forms of cancer and other diseases are treated using a medicinal combination of a SIRPαFc to block binding with CD47, and an anti-VEGF agent such as humanized antibody … |
PFIZER | 2022-11-01 | 2025-12-04 | |
| 25 | SUBSTITUTED PYRIDINE AND PHENYL COMPOUNDS Related Patents View Abstract: The invention relates to compounds of Formula (I), or pharmaceutically acceptable salts thereof; to their use in medicine; to compositions containing them; to processes for their … |
PFIZER | 2025-04-29 | 2025-11-13 | |
| 26 | Dosing Regimens of SIRP Alpha Fusion Proteins for Treatment of Cancer Related Patents View Abstract: Dosing regimens and methods for administering SIRPaFc fusion proteins are provided. The dosing regimens and methods include both SIRPaFc monotherapies and combination therapies. … |
PFIZER | 2023-05-22 | 2025-11-13 | |
| 27 | MULTI-LAYERED SYRINGE WITH A THREADED CONNECTION PART AND METHOD OF MANUFACTURING SAME Related Patents View Abstract: The invention relates to a syringe comprising an elongated main body having a nozzle formed at a distal end thereof and a threaded connection part at least partially surrounding … |
PFIZER | 2023-04-21 | 2025-11-13 | |
| 28 | GLP-1 Receptor Agonists and Uses Thereof Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising … |
PFIZER | 2025-07-16 | 2025-11-06 | |
| 29 | METHOD AND APPARATUS FOR IMPROVED MAN-MACHINE INTERACTIONS Related Patents View Abstract: An automated smart voice-interactive platform allows users to securely register with a provider and have physical conditions monitored, in place of interacting with a variety of … |
PFIZER | 2025-05-02 | 2025-11-06 | |
| 30 | METHOD AND SYSTEM OF SIMULATING OPERATIONAL INTEGRITY OF A PRE-FILLED VIAL Related Patents View Abstract: Method and system of digitally simulating operational integrity of a pre-filled vial. The method includes simulating, in a processor of a computing system, a frictional … |
PFIZER | 2025-05-02 | 2025-11-06 | |
| 31 | IMMUNOGENIC COMPOSITIONS AGAINST INFLUENZA Related Patents View Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines comprising polynucleotide molecules encoding one … |
PFIZER | 2024-11-13 | 2025-10-30 | |
| 32 | IMMUNOGENIC COMPOSITIONS AGAINST INFLUENZA Related Patents View Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines comprising polynucleotide molecules encoding one … |
PFIZER | 2024-09-11 | 2025-10-30 | |
| 33 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF Related Patents View Abstract: Described herein are compounds of Formula I: and their pharmaceutically acceptable salts, wherein R , R , R , R , A , L , L , T , T , T , T , n1, t1, t2, and t3 are defined … |
PFIZER | 2025-04-21 | 2025-10-23 | |
| 34 | ANTI-GDF15 ANTIBODIES, COMPOSITIONS AND METHODS OF USE Related Patents View Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to GDF15, as well as methods and uses for the antibodies. … |
PFIZER | 2025-01-17 | 2025-10-23 | |
| 35 | Nitrogen-Containing Heterocyclic Compounds Related Patents View Abstract: The disclosure relates to compounds of the disclosure and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for … |
PFIZER | 2025-04-10 | 2025-10-16 | |
| 36 | COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIUM DIFFICILE Related Patents View Abstract: In one aspect, the invention relates to an immunogenic composition that includes a toxoid A and/or a toxoid B, and methods of use thereof. In another aspect, the invention … |
PFIZER | 2025-06-23 | 2025-10-09 | |
| 37 | RSV F Protein Mutants Related Patents View Abstract: The present disclosure relates to RSV F protein mutants, nucleic acids or vectors encoding a RSV F protein mutant, compositions comprising a RSV F protein mutant or nucleic acid, … |
PFIZER | 2025-06-18 | 2025-10-09 | |
| 38 | Process for Producing of Vaccine Formulations With Preservatives Related Patents View Abstract: The present invention relates to a process for the production of a conjugate vaccine comprising a preservative. The invention relates in particular to a process for the production … |
PFIZER | 2023-05-08 | 2025-10-09 | |
| 39 | INJECTION DEVICE WITH A NEEDLE DETECTION FEATURE Related Patents View Abstract: The invention relates to an injection device comprising a housing, a needle connection ( ) for attaching a needle ( ) to a cartridge ( ) received in the housing ( ), an injection … |
PFIZER | 2023-05-12 | 2025-10-02 | |
| 40 | CYSTEINE PROTOTROPHY Related Patents View Abstract: Provided herein are cells, compositions, and related methods for improved cell growth. The expression of one or more of CBS, CTH, and GNMT genes is increased. In some embodiments, … |
PFIZER | 2023-01-30 | 2025-10-02 | |
| 41 | FORMULATIONS COMPRISING N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDE COMPOUNDS AND USES THEREOF Related Patents View Abstract: The present disclosure relates to compositions comprising N-substituted-dioxocyclobutenylamino-3-hydroxy-picoliamide compounds or a pharmaceutically acceptable salt or hydrate … |
PFIZER | 2025-03-20 | 2025-09-25 | |
| 42 | CRYSTALLINE PYRIMIDINYL-3,8-DIAZABICYCLO[3.2.1]OCTANYLMETHANONE COMPOUND AND USE THEREOF Related Patents View Abstract: The present invention discloses a novel crystalline form of … |
PFIZER | 2025-04-25 | 2025-09-11 | |
| 43 | IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED ESCHERICHIA COLI SACCHARIDES AND USES THEREOF Related Patents View Abstract: In one aspect, the present disclosure relates to an immunogenic composition comprising conjugated O-polysaccharide molecules derived from lipopolysaccharides. In one embodiment, … |
PFIZER | 2025-03-10 | 2025-09-11 | |
| 44 | COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE PROTECTIVE AGAINST LYME DISEASE Related Patents View Abstract: The present invention relates to methods of administering a composition comprising the OspA fusion proteins of SEQ ID NO: 1 (LipSI D1-S2D1), SEQ ID NO: 2 (Lip-S4D1-S3hybD1), and … |
PFIZER | 2023-04-24 | 2025-09-11 | |
| 45 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives Related Patents View Abstract: The present invention relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein Ring A, Ring B, R -R , n and p are defined herein. The novel … |
PFIZER et. al. | 2025-05-16 | 2025-09-04 | |
| 46 | GLP-1 Receptor Agonists and Uses Thereof Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising … |
PFIZER | 2025-05-15 | 2025-08-28 | |
| 47 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS Related Patents View Abstract: The invention relates to a method of treating a MEK-associated tumor by administering to a subject in need thereof a therapeutically effective amount of a solid form … |
PFIZER | 2025-04-30 | 2025-08-21 | |
| 48 | METHODS FOR PRODUCING NUCLEIC ACIDS Related Patents View Abstract: Described are methods for producing RNA molecules in an in vitro transcription reaction. Also described are methods for producing an mRNA molecule from a circular double-stranded … |
PFIZER | 2023-05-03 | 2025-08-21 | |
| 49 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods … |
PFIZER | 2025-05-02 | 2025-08-14 | |
| 50 | COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS Related Patents View Abstract: Provided herein is a compound of the Formula I: or a pharmaceutically acceptable salt thereof, wherein R , R , R , R , R , R , R and L are as defined herein, for the treatment of … |
PFIZER | 2025-04-16 | 2025-07-31 | |
| 51 | COMBINATION THERAPY USING GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONIST COMPOUNDS AND GLP-1 RECEPTOR AGONIST PEPTIDES Related Patents View Abstract: Described herein is a method of treating a disease or condition, for example, obesity, weight gain, or diabetes, comprising administering to a subject in need thereof a … |
PFIZER | 2025-01-23 | 2025-07-24 | |
| 52 | COMBINATION THERAPY USING GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONIST COMPOUNDS AND GLP-1 RECEPTOR AGONIST COMPOUNDS Related Patents View Abstract: Described herein is a method of treating a disease or condition, for example, obesity, weight gain, or diabetes, comprising administering to a subject in need thereof a … |
PFIZER | 2025-01-23 | 2025-07-24 | |
| 53 | ENHANCEMENT OF CD47 BLOCKADE WITH TAXANES FOR CD47+ CANCER THERAPY Related Patents View Abstract: The invention provides combinations of materials and methods for disease treatment, such as CD47+ cancer treatment. The combinations include a CD47 blocking agent and a taxane. … |
PFIZER | 2022-10-26 | 2025-07-24 | |
| 54 | Benzodiazepine Pyrazolo Carboxamides as N-protein Inhibitors Related Patents View Abstract: The invention relates to benzodiazepine pyrazolo carboxamides and pharmaceutically acceptable salts thereof as defined in the description; to their use in medicine; to … |
PFIZER | 2025-01-16 | 2025-07-17 | |
| 55 | PROCESS AND INTERMEDIATES USEFUL FOR PREPARING NIRMATRELVIR Related Patents View Abstract: The present invention is directed to intermediates and an efficient process for preparing nirmatrelvir (compound of Formula I) and intermediates useful in the preparation of … |
PFIZER | 2023-06-27 | 2025-07-17 | |
| 56 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH Related Patents View Abstract: The present invention relates to a compound of the formula I Wherein R to R , A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the … |
PFIZER | 2024-07-30 | 2025-07-03 | |
| 57 | INHIBITORS Related Patents View Abstract: Described herein are novel compounds in an isolated or crystalline form, pharmaceutical compositions and methods for the treatment of and prevention of various disorders, in … |
PFIZER | 2024-12-19 | 2025-06-26 | |
| 58 | Biphenyl and Phenylpyridine Compounds Related Patents View Abstract: The invention relates to compounds of Formula (1): and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their … |
PFIZER | 2024-12-06 | 2025-06-12 | |
| 59 | COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE Related Patents View Abstract: Technology is disclosed for a computerized system for monitoring a respiratory condition of a human subject, the system may include one or more processors, and a computer memory … |
PFIZER | 2023-03-02 | 2025-06-12 | |
| 60 | COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER Related Patents View Abstract: Provided are a combination therapy comprising inavolisib, palbociclib and fulvestrant and methods of treating PIC3CA-mutant, hormone receptor positive (HR+) and HER2 negative … |
GENENTECH; HOFFMANN-LA ROCHE; PFIZER | 2024-12-03 | 2025-06-05 | |
| 61 | METHODS FOR PRODUCING AN ADJUVANT Related Patents View Abstract: This invention provides methods for producing homogeneous and heterogeneous adjuvant formulations comprising a liposome bilayer comprising (a) monophosphoryl lipid A (MPLA), (b) a … |
PFIZER | 2023-03-09 | 2025-06-05 | |
| 62 | CORONAVIRUS ANTIGEN VARIANTS Related Patents View Abstract: The present disclosure provides isolated immunogenic polypeptides comprising variant coronavirus spike proteins that are variants of a native coronavirus spike protein or fragment … |
PFIZER | 2023-01-27 | 2025-06-05 | |
| 63 | DIGITAL MEDICINE COMPANION FOR CDK INHIBITOR MEDICATIONS FOR CANCER PATIENTS Related Patents View Abstract: The present disclosure relates to a digital medicine companion for patients undergoing oncology treatments. A patient may enter symptoms on a prescription software. A wearable … |
PFIZER | 2022-12-27 | 2025-05-29 | |
| 64 | NOVEL ANTIBODIES AND ANTIBODY CONJUGATES FOR THE TREATMENT OF METABOLIC DISORDERS Related Patents View Abstract: Disclosed herein are novel antibodies, novel agonist peptides, and novel dual agonist peptides. Further disclosed herein are novel antibody conjugates comprising the novel … |
PFIZER | 2024-11-14 | 2025-05-22 | |
| 65 | LFA3 VARIANTS AND COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The invention provides LFA3 polypeptide molecules, e.g., variant LFA3 fusion polypeptide molecules. The invention includes uses, and associated methods of using the LFA3 … |
PFIZER; REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-09-06 | 2025-05-22 | |
| 66 | Methods for Incorporating Azido Groups in Bacterial Capsular Polysaccharides Related Patents View Abstract: The present invention relates to fermentation methods for incorporating azido groups in bacterial capsular polysaccharides. The invention also relates to capsular polysaccharides … |
PFIZER | 2023-02-22 | 2025-05-22 | |
| 67 | ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF Related Patents View Abstract: The present invention provides antibodies that specifically bind to CD123. The invention further relates to immunoconjugates (e.g., antibody-drug conjugates, or ADCs) comprising … |
PFIZER | 2024-12-03 | 2025-05-15 | |
| 68 | ANTI-MIGIS-alpha ANTIBODIES AND METHODS OF USE THEREOF Related Patents View Abstract: Provided herein are antibodies (including antigen-binding fragments thereof) that specifically bind to MIGIS-α, including for example without limitation, bispecific MIGIS-α/CD3 … |
PFIZER et. al. | 2024-11-08 | 2025-05-15 | |
| 69 | TISSUE FACTOR PATHWAY INHIBITOR ANTIBODIES AND USES THEREOF Related Patents View Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful … |
PFIZER | 2024-11-05 | 2025-05-08 | |
| 70 | CHIMERIC ANTIGEN RECEPTORS TARGETING CD70 Related Patents View Abstract: The disclosure provides CARs (CARs) that specifically bind to CD70. The disclosure further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and … |
PFIZER | 2024-10-17 | 2025-05-08 | |
| 71 | Pyrrolo[2,3-d]pyrimidinyl, Pyrrolo[2,3-b]pyrazinyl and Pyrrolo[2,3-d]pyridinyl Acryla-mides Related Patents View Abstract: The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl and pyrrolo[2,3-d]pyridinyl acrylamides and analogues thereof. Such compounds are useful for … |
PFIZER | 2024-07-15 | 2025-05-01 | |
| 72 | AMPHIPHILIC TLR7/8 ADJUVANTS AND USES THEREOF Related Patents View Abstract: The invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, L, X, Y and p are as defined in the description; to their use in … |
PFIZER | 2024-07-03 | 2025-05-01 | |
| 73 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF Related Patents View Abstract: Described herein are compounds of Formula I: I and their pharmaceutically acceptable salts, wherein R , R , R , R , R , R , t1, Y , and Y are defined herein; their use as MC4R … |
PFIZER | 2022-12-05 | 2025-04-24 | |
| 74 | METHODS AND DOSING REGIMENS COMPRISING A CDK2 INHIBITOR FOR THE TREATMENT OF CANCER Related Patents View Abstract: The disclosure provides methods of treating cancer in a subject in need thereof comprising administering to the subject a therapeutically effective amount of PF-07104091, as a … |
PFIZER | 2022-12-01 | 2025-04-24 | |
| 75 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives Related Patents View Abstract: The present invention relates to compounds of Formula (I): … |
PFIZER et. al. | 2024-10-01 | 2025-04-17 | |
| 76 | ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF Related Patents View Abstract: In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from lipopolysaccharides and conjugates thereof. … |
PFIZER | 2024-09-09 | 2025-04-17 | |
| 77 | MULTIPLEXED BIOLOGICAL ASSAY DEVICE WITH ELECTRONIC READOUT Related Patents View Abstract: This invention relates generally to devices, systems, and methods for performing biological assays by using indicators that modify one or more optical properties of the assayed … |
PFIZER | 2024-12-19 | 2025-04-10 | |
| 78 | ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF Related Patents View Abstract: This invention relates to compositions that include a polypeptide derived from or a fragment thereof; and modified O-polysaccharide molecules derived from lipopolysaccharides … |
PFIZER | 2024-09-09 | 2025-04-10 | |
| 79 | KLF2 INDUCING DEUTERATED COMPOUNDS AND USES THEREOF Related Patents View Abstract: The present disclosure provides deuterated compounds that are inducers of KLF2 and pharmaceutical compositions comprising the same. The present disclosure further provides method … |
RIPARIAN PHARMACEUTICALS; PFIZER | 2024-08-02 | 2025-04-03 | |
| 80 | Nitrile-Containing Antiviral Compounds Related Patents View Abstract: The invention relates to compounds of Formula I″ wherein R, R , R , R , p, q and q′ are as defined herein, pharmaceutical compositions comprising the compounds, methods of … |
PFIZER | 2024-10-16 | 2025-03-27 | |
| 81 | Crystalline form of (2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3-pyrrolidin]-1-yl]propan-1-one Related Patents View Abstract: Described herein is a crystalline form of … |
PFIZER | 2024-11-21 | 2025-03-13 | |
| 82 | AQUEOUS FORMULATION COMPRISING 1-(4-{[4-(DIMETHYLAMINO)PIPERIDIN-1-YL]CARBONYL}PHENYL)-3-[4-(4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL)PHENYL]UREA Related Patents View Abstract: The present invention relates to a pharmaceutical aqueous formulation comprising … |
PFIZER | 2024-09-05 | 2025-02-27 | |
| 83 | Deuterated Antiviral Compounds Related Patents View Abstract: The invention relates to compounds of Formula (I) wherein Y , Y , Y , Y , Y , Y , Y , Y , Y , Y and Y are as defined herein and to their use in medicine; to compositions … |
PFIZER | 2024-08-09 | 2025-02-13 | |
| 84 | COMBINATION THERAPIES AND USES FOR TREATING CANCER Related Patents View Abstract: The present disclosure relates to the treatment of cancer and/or cancer-associated disease. Certain aspects relate to the treatment of an individual having cancer or … |
PFIZER | 2022-12-12 | 2025-02-13 | |
| 85 | BLISTER PACKAGING FOR PHARMACEUTICALS Related Patents View Abstract: A blister package is disclosed herein. The blister package includes a body, a plurality of pockets, and a top seal. The body has a top surface and a bottom surface opposite the … |
PFIZER | 2022-12-16 | 2025-02-06 | |
| 86 | METHODS AND DOSING REGIMENS COMPRISING A CDK2 INHIBITOR AND A CDK4 INHIBITOR FOR TREATING CANCER Related Patents View Abstract: This disclosure relates to combination therapies for use in treating cancer, comprising a CDK2 inhibitor of Formula (I) and a selective CDK4 inhibitor of Formula (II), each as … |
PFIZER | 2022-12-01 | 2025-02-06 | |
| 87 | CDK4 INHIBITOR FOR THE TREATMENT OF CANCER Related Patents View Abstract: The disclosure provides a method of treating cancer comprising administering to a subject in need thereof with a therapeutically effective amount of PF-07220060. The disclosure … |
PFIZER; PFIZER | 2022-11-29 | 2025-02-06 | |
| 88 | PYRIDO[4,3-D]PYRIMIDINE COMPOUNDS Related Patents View Abstract: The invention relates to compounds of Formula (I)-(III) and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for … |
PFIZER | 2024-10-01 | 2025-01-30 | |
| 89 | ANTIBODIES SPECIFIC FOR CD70 AND THEIR USES Related Patents View Abstract: The present invention provides antibodies that specifically bind to CD70 (Cluster of Differentiation 70). The invention further provides bispecific antibodies that bind to CD70 … |
PFIZER | 2024-04-18 | 2025-01-09 | |
| 90 | IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS, KITS COMPRISING THE SAME AND USES THEREOF Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions … |
PFIZER | 2024-03-19 | 2025-01-09 | |
| 91 | HEALTH INFORMATION PLATFORM Related Patents View Abstract: A system and methods of providing credibility and trustworthiness to users in a wellness platform. A method for providing search results to a user in an app including searching a … |
PFIZER | 2024-06-26 | 2025-01-02 | |
| 92 | POLYNUCLEOTIDE COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The invention relates to RNA molecules encoding an fimbrial H antigen (FimH). The present disclosure further relates to compositions comprising the RNA molecules formulated in a … |
PFIZER | 2024-06-11 | 2025-01-02 | |
| 93 | COMPOSITIONS AND METHODS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN Related Patents View Abstract: In one aspect, the invention relates to an immunogenic composition that includes a mutant toxin A and/or a mutant toxin B. The mutant toxin may include a glucosyltransferase … |
PFIZER | 2024-03-01 | 2025-01-02 | |
| 94 | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF Related Patents View Abstract: The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC’s), and to payload-linker compounds and ADC compounds … |
PFIZER | 2024-04-05 | 2024-12-12 | |
| 95 | SYSTEMS AND METHODS FOR PERFORMING BIOLOGICAL ASSAYS Related Patents View Abstract: Systems and methods for performing biological assays are provided herein. The systems and methods determine one or more characteristics of a nucleic acid amplification sample … |
PFIZER | 2024-08-15 | 2024-12-05 | |
| 96 | WEARABLE COMPANION FOR DETECTING THE CYTOKINE RELEASE SYNDROME Related Patents View Abstract: Embodiments disclosed herein may provide digital medicine support for predicting and mitigating side effects of bispecific antibody treatment (e.g., Pfizer’s Elranatamab) for … |
PFIZER | 2022-12-22 | 2024-12-05 | |
| 97 | METABOLITES OF GLP1R AGONISTS Related Patents View Abstract: The present invention provides compounds of Formula XA-1, XA-2, XA-3, XA-4, XA-5, or XA-6, or metabolites of Compound 1 or metabolites of a compound of Formula I, PA-I, or PA-III, … |
PFIZER | 2024-07-31 | 2024-11-28 | |
| 98 | Modulators of STING (Stimulator of Interferon Genes) Related Patents View Abstract: Provided herein are compounds of the general formula (I): and pharmaceutically acceptable salts thereof, processes for the preparation of these compounds, compositions containing … |
PFIZER | 2024-03-18 | 2024-11-21 | |
| 99 | DIGITAL MEDICINE COMPANION FOR TREATING AND MANAGING SKIN DISEASES Related Patents View Abstract: A digital medicine companion for managing skin diseases (e.g., atopic dermatitis, psoriasis) may include patient wearable devices passively collecting patient data, patient user … |
PFIZER | 2022-12-16 | 2024-11-21 | |
| 100 | Immunogenic Compositions Comprising Conjugated Capsular Saccharide Antigens and Uses Thereof Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of … |
PFIZER | 2023-12-06 | 2024-11-14 | |
| 101 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF Related Patents View Abstract: Described herein are compounds of Formula I: and their pharmaceutically acceptable salts, wherein R , R , R , L , T , T , T , T , t1, and t2 are defined herein; their use as GIPR … |
PFIZER | 2024-04-12 | 2024-11-07 | |
| 102 | N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS Related Patents View Abstract: The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate … |
PFIZER | 2023-05-03 | 2024-11-07 | |
| 103 | LILRB1 and LILRB2 ANTIBODIES AND METHODS OF USE THEREOF Related Patents View Abstract: The invention is directed to Anti-LILRB1 and anti-LILRB2 bispecific antibodies, anti-LILRB1 antibodies, and anti-LILRB2 antibodies, their uses and pharmaceutical compositions … |
PFIZER | 2024-04-18 | 2024-10-31 | |
| 104 | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions … |
PFIZER | 2024-04-12 | 2024-10-24 | |
| 105 | SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF Related Patents View Abstract: The invention relates to substituted indazole propionic acid derivatives, pharmaceutically acceptable salts, tautomers, or pharmaceutically acceptable salts of the tautomers … |
PFIZER | 2024-04-04 | 2024-10-10 | |
| 106 | Pyrido[4,3-d]pyrimidine Compounds Related Patents View Abstract: The invention relates to compounds of Formula (I)-(III) and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for … |
PFIZER | 2024-04-03 | 2024-10-10 | |
| 107 | COMBINATION THERAPY COMPRISING A PKC INHIBITOR AND A C-MET INHIBITOR Related Patents View Abstract: Provided herein is a combination therapy and methods of using such combination therapy to treat diseases or disorders associated with PKC and c-MET. … |
IDEAYA BIOSCIENCES et. al. | 2022-12-05 | 2024-10-10 | |
| 108 | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions … |
PFIZER | 2024-03-29 | 2024-10-03 | |
| 109 | ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF Related Patents View Abstract: This invention provides a polypeptide derived from or a fragment thereof, including compositions and methods thereof. In one embodiment, the compositions comprise a polypeptide … |
PFIZER | 2024-03-06 | 2024-10-03 | |
| 110 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS Related Patents View Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the … |
PFIZER | 2024-03-18 | 2024-09-26 | |
| 111 | IMMUNOGENIC COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The invention relates to immunogenic compositions comprising a capsular polysaccharide (CP) from , commonly referred to as group B (GBS), conjugated to a carrier protein, and … |
PFIZER | 2024-05-10 | 2024-09-12 | |
| 112 | SOLID FORMS OF PYRAZOLO[3,4-D]PYRIMIDINE COMPOUNDS Related Patents View Abstract: The present disclosure provides solid forms of … |
PFIZER | 2024-05-06 | 2024-09-12 | |
| 113 | SELECTIVELY VENTED BIOLOGICAL ASSAY DEVICES AND ASSOCIATED METHODS Related Patents View Abstract: Selectively vented biological assay devices and methods of performing biological assays with such devices are provided herein. Disclosed devices include a selective venting … |
PFIZER | 2024-05-01 | 2024-09-12 | |
| 114 | CDK2 INHIBITORS Related Patents View Abstract: This invention relates to compounds of Formula (I) … |
PFIZER | 2023-07-05 | 2024-09-05 | |
| 115 | CETYLTRIMETHYLAMMONIUM BROMIDE (CTAB) AS A LYSIS AND FLOCCULATION REAGENT IN GENE THERAPY DOWNSTREAM PROCESSES Related Patents View Abstract: The present disclosure describes improved methods for use in purifying biological products made by host cells. In some embodiments, the improved methods comprise one or more steps … |
PFIZER | 2024-02-26 | 2024-08-29 | |
| 116 | ANTI-CXCR5 ANTIBODIES AND COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared … |
PFIZER; REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-03-04 | 2024-08-22 | |
| 117 | Devices and Methods for Modifying Optical Properties Related Patents View Abstract: Devices and methods for modifying optical properties of biological samples or aspects thereof are provided. The subject methods include generating a reaction product with a device … |
PFIZER | 2024-04-15 | 2024-08-15 | |
| 118 | ANTI-EDB ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Related Patents View Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same. … |
PFIZER | 2023-12-04 | 2024-08-08 | |
| 119 | VACCINES AGAINST RESPIRATORY DISEASES Related Patents View Abstract: The present disclosure relates to hMPV F, PIV3 F and PIV1 F protein mutants, nucleic acids or vectors encoding a hMPV F, PIV3 F and PIV1 F protein mutant, compositions comprising … |
PFIZER | 2024-01-16 | 2024-08-01 | |
| 120 | IMMUNOGENIC COMPOSITIONS AND USES THEREOF Related Patents View Abstract: The present disclosure relates to compositions comprising RNA molecules encoding an antigen derived from influenza, wherein the RNA may be formulated in a lipid nanoparticle … |
PFIZER | 2023-12-07 | 2024-08-01 | |
| 121 | BTLA Fusion Protein Agonists and Uses Thereof Related Patents View Abstract: The present invention is based on the seminal discovery that BTLA agonist fusion proteins modulate an immune response. Specifically, the present invention provides fusion proteins … |
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE; PFIZER | 2024-02-15 | 2024-07-25 | |
| 122 | Papain-like protease (PLpro) inhibitors Related Patents View Abstract: The invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof as defined in the description; to their use in medicine; to compositions containing … |
PFIZER | 2023-12-07 | 2024-07-25 | |
| 123 | IMMUNOGENIC COMPOSITIONS FOR USE IN PNEUMOCOCCAL VACCINES Related Patents View Abstract: An object of the present invention is to provide immunogenic compositions for protection against , in particular against serogroup 10A and 39, while limiting the number of … |
PFIZER | 2024-02-01 | 2024-07-18 | |
| 124 | HSD17B13 Inhibitors and/or Degraders Related Patents View Abstract: Described herein are 3-fluoro-4-hydroxybenzamide-containing inhibitors and/or degraders, and pharmaceutical compositions containing 3-fluoro-hydroxybenzamide-containing inhibitors … |
PFIZER | 2023-12-15 | 2024-07-18 | |
| 125 | CLAUDIN 18.2 TARGETING CHIMERIC ANTIGEN RECEPTORS AND BINDING AGENTS AND USES THEREOF Related Patents View Abstract: Provided herein are Claudin 18.2 binding agents and chimeric antigen receptors (CARs) comprising a Claudin 18.2 binding molecule that specifically binds to Claudin 18.2; and … |
ALLOGENE THERAPEUTICS et. al. | 2023-11-28 | 2024-07-04 | |
| 126 | COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIUM DIFFICILE Related Patents View Abstract: In one aspect, the invention relates to an immunogenic composition that includes a toxoid A and/or a toxoid B, and methods of use thereof. In another aspect, the invention … |
PFIZER | 2023-08-09 | 2024-07-04 | |
| 127 | Azalactam Compounds as HPK1 Inhibitors Related Patents View Abstract: This invention relates to compounds of general Formula I … |
PFIZER | 2023-05-08 | 2024-06-20 | |
| 128 | IMMUNOGENIC COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIOIDES (CLOSTRIDIUM) DIFFICILE Related Patents View Abstract: The present invention relates to immunogenic compositions that comprise a toxoid A and/or a toxoid B, and an adjuvant, and methods of use thereof. The present invention further … |
PFIZER | 2023-12-11 | 2024-06-13 | |
| 129 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES Related Patents View Abstract: The present invention provides, in part, compounds of Formula I: or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: R , R , L, … |
PFIZER | 2023-12-07 | 2024-06-13 | |
| 130 | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof Related Patents View Abstract: The present invention relates to new immunogenic compositions comprising conjugated capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of … |
PFIZER | 2023-11-20 | 2024-06-06 | |
| 131 | ANTI-EDB ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Related Patents View Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same. … |
PFIZER | 2023-10-23 | 2024-06-06 | |
| 132 | COMPOUNDS FOR THE ACTIVATION OF AMPK Related Patents View Abstract: Described herein are compounds of Formula I, … |
PFIZER | 2023-10-11 | 2024-06-06 | |
| 133 | INTERFERON BETA ANTIBODIES AND USES THEREOF Related Patents View Abstract: The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta (IFNβ). Such antibodies, or antigen-binding fragments … |
PFIZER et. al. | 2023-11-16 | 2024-05-30 | |
| 134 | ORAL SOLUTION FORMULATION Related Patents View Abstract: The present invention relates to an oral solution formulation or an oral powder for constitution comprising … |
PFIZER | 2024-01-23 | 2024-05-16 | |
| 135 | Antibody Purification Related Patents View Abstract: Antibody compositions and methods for the purification of antibodies are provided. Purification methods provided involve the use of hydroxyapatite resin (HA) to separate an … |
PFIZER | 2023-12-21 | 2024-05-16 | |
| 136 | ANTI-EDB ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Related Patents View Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same. … |
PFIZER | 2023-10-23 | 2024-05-16 | |
| 137 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2024-01-16 | 2024-05-09 | |
| 138 | HSD17B13 INHIBITORS AND/OR DEGRADERS Related Patents View Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing … |
PFIZER | 2023-10-06 | 2024-05-09 | |
| 139 | PURIFICATION OF ANTIBODY DRUG CONJUGATES USING A SODIUM PHOSPHATE GRADIENT Related Patents View Abstract: Methods of removing high molecular weight species, in particular aggregates, from antibody drug conjugate preparations, by contacting preparations of the antibody drug conjugate … |
PFIZER | 2023-05-23 | 2024-05-09 | |
| 140 | Diacylglycerol Acyl Transferase 2 Inhibitors Related Patents View Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are … |
PFIZER | 2023-11-28 | 2024-05-02 | |
| 141 | COMPOUND FOR THE TREATMENT OF CANCER Related Patents View Abstract: The invention relates to 4-((6-(2,2-Difluoroethyl)-8-(2-hydroxy-2-methylcyclopentyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)piperidine-1-sulfonamide or … |
PFIZER | 2023-10-17 | 2024-05-02 | |
| 142 | GLP-1 Receptor Agonists and Uses Thereof Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising … |
PFIZER | 2023-11-20 | 2024-04-25 | |
| 143 | Colorimetric Detection of Nucleic Acid Amplification Related Patents View Abstract: Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces … |
PFIZER | 2023-02-20 | 2024-04-25 | |
| 144 | Novel SIK Inhibitors Related Patents View Abstract: A compound of formula I having the structure: or a pharmaceutically acceptable salt thereof, wherein A and A are independently O or S; X is selected from CH , CD , NR , O, and S, … |
PFIZER | 2023-09-13 | 2024-04-18 | |
| 145 | Antibodies Specific for CD47, PD-L1, and Uses Thereof Related Patents View Abstract: Antibodies that specifically bind to CD47 and antibodies that specifically bind to PD-L1 are provided, as well as CD47/PD-L1 bispecific antibodies. Also provided are uses of these … |
PFIZER | 2023-05-18 | 2024-04-18 | |
| 146 | MULTISPECIFIC ANTIBODIES AND USES THEREOF Citation: 1 Related Patents View Abstract: The present invention relates to antibodies that specifically bind to one or more of IL-4, IL-13, IL-33, TSLP, and p40. The present invention further relates to antibodies that … |
PFIZER | 2023-02-28 | 2024-04-11 | |
| 147 | NOVEL ACC INHIBITORS Related Patents View Abstract: A compound having the structures: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, … |
PFIZER | 2023-07-26 | 2024-04-04 | |
| 148 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH Related Patents View Abstract: The present invention relates to a compound of the formula I wherein R to R , A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the … |
PFIZER | 2023-03-15 | 2024-04-04 | |
| 149 | HUMAN CYTOMEGALOVIRUS GB POLYPEPTIDE Related Patents View Abstract: The present invention relates to polypeptides and cytomegalovirus (CMV) antigens that include at least two introduced amino acid mutations relative to the amino acid sequence of … |
PFIZER | 2023-11-10 | 2024-03-28 | |
| 150 | B-CELL MATURATION ANTIGEN (BCMA) ANTI-IDIOTYPIC ANTIBODIES Related Patents View Abstract: Provided herein are anti-idiotype antibodies that specifically recognize anti-BCMA antibody moieties, in particular, anti-BCMA antibody moieties present in recombinant receptors, … |
ALLOGENE THERAPEUTICS et. al. | 2023-09-18 | 2024-03-28 | |
| 151 | CELLS AND METHOD OF CELL CULTURE Related Patents View Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention … |
PFIZER | 2023-07-12 | 2024-03-21 | |
| 152 | ANTI-BMP9 ANTIBODIES AND METHODS OF USE THEREOF Related Patents View Abstract: Antibodies, and antigen-binding fragments thereof, that specifically bind to bone morphogenetic protein-9 (BMP9) are provided. Embodiments include uses, and associated methods of … |
PFIZER; BRIGHAM AND WOMEN’S HOSPITAL; GENERAL HOSPITAL | 2023-05-31 | 2024-03-14 | |
| 153 | CD1a ANTIBODIES AND USES THEREOF Related Patents View Abstract: Antibodies, and antigen-binding fragments thereof, that specifically bind to Cluster of Differentiation 1a (CD1a) are provided. Embodiments include uses, and associated methods of … |
PFIZER; CHILDREN’S MEDICAL CENTER | 2023-07-19 | 2024-03-07 | |
| 154 | ANTI-E-SELECTIN ANTIBODIES, COMPOSITIONS AND METHODS OF USE Related Patents View Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to E-selectin. The invention includes uses, and associated methods of using the … |
PFIZER | 2023-02-27 | 2024-03-07 | |
| 155 | GLP-1 Receptor Agonists and Uses Thereof Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising … |
PFIZER | 2023-10-09 | 2024-02-22 | |
| 156 | ANTI-TL1A ANTIBODIES AND METHODS OF USE THEREOF Citation: 2 Related Patents View Abstract: The present invention discloses an isolated antibody that specifically binds to TL1A, comprising a heavy chain variable region (TL1A-VH) and a light chain variable region … |
PFIZER; BRISTOL-MYERS SQUIBB | 2023-05-09 | 2024-02-22 | |
| 157 | ANTI- IL27R ANTIBODIES AND METHODS OF USE THEREOF Related Patents View Abstract: The present invention relates to antibodies that specifically bind to one or both of IL27RA and gp130. The present invention further relates to bispecific antibodies that … |
PFIZER | 2023-08-01 | 2024-02-15 | |
| 158 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2023-07-28 | 2024-02-15 | |
| 159 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods … |
PFIZER | 2023-09-28 | 2024-02-01 | |
| 160 | IMMUNOGENIC GLYCOPROTEIN CONJUGATES Related Patents View Abstract: The present invention relates generally to glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a spacer containing ((2-oxoethyl)thio)). In … |
PFIZER | 2023-06-06 | 2024-02-01 | |
| 161 | CD47 BLOCKADE THERAPY WITH CD38 ANTIBODY Related Patents View Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and a CD38 antibody such as daratumumab. The anti-cancer effect of SIRPαFc is … |
PFIZER | 2023-08-30 | 2024-01-18 | |
| 162 | THERAPEUTIC ANTIBODIES AND THEIR USES Related Patents View Abstract: The present invention relates to antibodies, e.g., full length antibodies or antigen binding fragments thereof, that specifically bind to BCMA (B-Cell Maturation Antigen) and/or … |
PFIZER | 2023-08-25 | 2024-01-18 | |
| 163 | THERAPEUTIC ANTIBODIES AND THEIR USES Related Patents View Abstract: The present invention relates to antibodies that specifically bind to B7-H4 (B7 Homology 4, encoded by gene VTCN1) and bispecific antibodies that specifically bind to both B7-H4 … |
PFIZER | 2023-08-15 | 2024-01-18 | |
| 164 | IMAGE-BASED DISEASE DIAGNOSTICS USING A MOBILE DEVICE Related Patents View Abstract: A diagnostic system performs disease diagnostic tests using at least an optical property modifying device and a mobile device. A user provides a biological sample from a patient … |
PFIZER | 2023-08-02 | 2024-01-18 | |
| 165 | SELF-AMPLIFYING RNA ENCODING AN INFLUENZA VIRUS ANTIGEN Related Patents View Abstract: Self-amplifying RNA (saRNA) molecules encoding an influenza virus antigen and methods of use thereof are disclosed herein. … |
PFIZER | 2023-07-06 | 2024-01-11 | |
| 166 | IL-12 Variants and Uses Thereof Related Patents View Abstract: IL-12 variants are provided. Also provided are antibodies that specifically bind to PD1. Also provided are fusion proteins of IL-12 variants and anti-PD1 antibodies. Also provided … |
PFIZER | 2023-06-15 | 2024-01-11 | |
| 167 | COMBINATION PRODUCT FOR THE TREATMENT OF CANCER Related Patents View Abstract: Methods of administering a therapeutically effective amount of Debio 1143 and a therapeutically effective amount of an anti-PD-L1 antibody or antigen-binding fragment thereof, for … |
DEBIOPHARM INTERNATIONAL; MERCK PATENT; PFIZER | 2023-06-02 | 2024-01-11 | |
| 168 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS Related Patents View Abstract: The invention relates to a method of treating a MEK-associated tumor by administering to a subject in need thereof a therapeutically effective amount of a solid form … |
PFIZER | 2023-09-18 | 2024-01-04 | |
| 169 | CELL CULTURE PROCESS Related Patents View Abstract: A cell culture medium comprising tyrosine at a concentration of at least 3 mM and polyvinylalcohol (PVA). … |
PFIZER | 2023-08-31 | 2023-12-28 | |
| 170 | NEISSERIA MENINGITIDIS COMPOSITIONS AND METHODS THEREOF Related Patents View Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a non-serogroup B capsular polysaccharide. The invention further relates to … |
PFIZER | 2023-06-29 | 2023-12-28 | |
| 171 | TISSUE FACTOR PATHWAY INHIBITOR ANTIBODIES AND USES THEREOF Related Patents View Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful … |
PFIZER | 2023-03-13 | 2023-12-28 | |
| 172 | ANTI-TNFR2 ANTIBODIES AND METHODS OF USE THEREOF Related Patents View Abstract: The present disclosure provides antibodies that bind to TNFR2 as well as uses of the antibodies and associated methods. The disclosure also provides processes for making, … |
PFIZER | 2023-05-25 | 2023-12-21 | |
| 173 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2023-01-20 | 2023-12-21 | |
| 174 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Citation: 2 Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2023-07-28 | 2023-11-30 | |
| 175 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) Related Patents View Abstract: Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and … |
PFIZER | 2023-07-24 | 2023-11-30 | |
| 176 | Chemical Compounds Related Patents View Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such … |
PFIZER | 2023-05-24 | 2023-11-30 | |
| 177 | ANTI-LYMPHOTOXIN BETA RECEPTOR ANTIBODIES AND METHODS OF USE THEREOF Related Patents View Abstract: Antibodies that specifically bind to LTBR are provided. Also provided are uses of these antibodies, and related compositions and methods. … |
PFIZER | 2023-05-10 | 2023-11-16 | |
| 178 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS Related Patents View Abstract: The invention provides eTEC linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, … |
PFIZER | 2023-06-21 | 2023-11-09 | |
| 179 | ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF Related Patents View Abstract: The present invention provides antibodies that specifically bind to CD123. The invention further relates to immunoconjugates (e.g., antibody-drug conjugates, or ADCs) comprising … |
PFIZER | 2023-03-08 | 2023-11-09 | |
| 180 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF Related Patents View Abstract: The invention relates to immunogenic polysaccharide-protein conjugates comprising a capsular polysaccharide (CP) from , commonly referred to as group B streptococcus (GBS), and a … |
PFIZER | 2022-12-01 | 2023-11-02 | |
| 181 | Bicyclic-Fused Heteroaryl or Aryl Compounds Related Patents View Abstract: Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. … |
PFIZER | 2023-06-28 | 2023-10-26 | |
| 182 | ANTIBODIES SPECIFIC FOR GUCY2C AND USES THEREOF Related Patents View Abstract: The present invention provides novel antibodies that specifically bind to GUCY2c and uses thereof in the treatment of cancer. The present invention further provides novel … |
PFIZER | 2022-10-27 | 2023-10-26 | |
| 183 | N1-Pyrazolospiroketone Acetyl-CoA Carboxylase Inhibitors Related Patents View Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R , R , R , Z, A , L and A are as described herein; pharmaceutical … |
PFIZER | 2023-05-03 | 2023-10-12 | |
| 184 | METHODS, DOSAGE REGIMENS, AND COMPOSITIONS FOR TREATING HIDRADENITIS Related Patents View Abstract: There are methods, dosage regimens, and compositions for treating hidradenitis suppurativa. … |
PFIZER | 2023-03-08 | 2023-09-21 | |
| 185 | DLL3 TARGETING CHIMERIC ANTIGEN RECEPTORS AND BINDING AGENTS Related Patents View Abstract: Provided herein are DLL3 binding agents and chimeric antigen receptors (CARs) comprising a DLL3 binding molecule that specifically binds to DLL3; and immune cells comprising these … |
ALLOGENE THERAPEUTICS et. al. | 2023-04-27 | 2023-09-14 | |
| 186 | Benzimidazole Derivative Compounds and Uses Thereof Related Patents View Abstract: The invention relates to benzimidazoles of Formula (1) and pharmaceutically acceptable salts thereof, wherein R to R are as defined in the description; to their use in medicine; … |
PFIZER | 2023-04-17 | 2023-09-07 | |
| 187 | COMBINATION OF AN ANTI-PD-L1 ANTIBODY AND A DNA-PK INHIBITOR FOR THE TREATMENT OF CANCER Related Patents View Abstract: The present invention relates to combination therapies useful for the treatment of cancer. In particular, the invention relates to a therapeutic combination which comprises an … |
MERCK PATENT et. al. | 2022-12-23 | 2023-08-31 | |
| 188 | ANTI-EDB ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Related Patents View Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same. … |
PFIZER | 2023-02-09 | 2023-08-03 | |
| 189 | RSV F Protein Mutants Related Patents View Abstract: The present disclosure relates to RSV F protein mutants, nucleic acids or vectors encoding a RSV F protein mutant, compositions comprising a RSV F protein mutant or nucleic acid, … |
PFIZER | 2023-03-29 | 2023-07-13 | |
| 190 | PHARMACEUTICAL AQUEOUS FORMULATION COMPRISING 1-(4-{[4-(DIMETHYLAMINO)PIPERIDIN-1-YL]CARBONYL}PHENYL)-3-[4-(4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL)PHENYL]UREA Citation: 1 Related Patents View Abstract: The present invention relates to a pharmaceutical aqueous formulation comprising … |
PFIZER | 2022-11-30 | 2023-07-13 | |
| 191 | GLYCOCONJUGATION PROCESS Related Patents View Abstract: The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related … |
PFIZER | 2023-03-01 | 2023-06-29 | |
| 192 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Citation: 2 Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2023-02-17 | 2023-06-29 | |
| 193 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES Related Patents View Abstract: The present invention provides, in part, compounds of Formula I: or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: R , R , L, … |
PFIZER | 2023-02-21 | 2023-06-22 | |
| 194 | SOLID FORMS OF PYRAZOLO[3,4-D]PYRIMIDINE COMPOUNDS Related Patents View Abstract: The present disclosure provides solid forms of … |
PFIZER | 2022-12-16 | 2023-06-22 | |
| 195 | METHODS FOR ANTAGONIZING A MELANOCORTIN 4 RECEPTOR Related Patents View Abstract: Described herein are methods of treating MC4R-related conditions, diseases, or disorders by administering compounds of Formula I: … |
PFIZER | 2023-01-31 | 2023-06-08 | |
| 196 | SOLID STATE FORMS OF (S)-2-(((S)-6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)AMINO)-N-(1-(2-METHYL-1-(NEOPENTYLAMINO)PROPAN-2-YL)-1H-IMIDAZOL-4-YL)PENTANAMIDE AND USES THEREOF Related Patents View Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of … |
PFIZER | 2023-01-27 | 2023-06-01 | |
| 197 | BCKDK INHIBITORS AND/OR DEGRADERS Related Patents View Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors and/or … |
PFIZER | 2022-11-30 | 2023-06-01 | |
| 198 | Boron Containing PDE4 Inhibitors Related Patents View Abstract: The present invention relates to boron containing compounds of Formula (I) X—Y—Z Formula (I) that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses … |
PFIZER | 2022-12-15 | 2023-05-11 | |
| 199 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS Related Patents View Abstract: The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R , R , R and R are as defined herein. The invention further relates to … |
PFIZER | 2022-12-01 | 2023-04-20 | |
| 200 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF Citation: 9 Related Patents View Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods … |
PFIZER | 2022-10-24 | 2023-04-20 |