Clinical Digest: Recent Clinical Trials on Giardiasis
To assist researchers and healthcare practitioners in staying up-to-date with the latest advancements in clinical research, the Clinical Digest Team has compiled a comprehensive list of recent clinical trials related to Giardiasis. These trials are organized by their release dates for your convenience. (Last updated on: 2025-05-02)
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TABLE 1: Clinical Digest: Recent Clinical Trials on Giardiasis
| Clinical Trial | Contact(s) | Date | |
|---|---|---|---|
| 1 | İmportance of Scattered White Spots Detected in The Duodenum and Their Relationship Wıth Zonulin PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: With our study, we aimed to determine whether there is a correlation between zonulin, which plays a crucial role in intestinal barrier function and is implicated in the etiopathogenesis of many chronic and autoimmune diseases, and scattered white spots lesions associated with lymphatic stasis and inflammation in the duodenum. |
SEMIH SEZER; | 2023-09-01 |
| 2 | Evaluation of The Diagnostic Role of Enteroscopy in Small Intestinal Diseases at Al-Rajhi University Hospital PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: To identify the role of enteroscopy in diagnosis and treatment of small intestinal diseases. |
MAIADA MOHIE ELDIN IBRAHIM; | 2022-08-01 |
| 3 | Anti-protozoal Effect of Steroid Hormone 20-hydroxyecdysone PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: 20-hydroxyecdysone is an ecdysteroid hormone found in invertebrates and plants. 20-hydroxyecdysone exhibits a broad range of biological properties in various in vitro and in vivo models, including anabolic, antioxidant, anti-inflammatory, immunomodulatory, anti-obesity and antidiabetic activities, in addition to acting as neuroprotective and hepatoprotective agent. Ecdysteroids are widely used by athletes as dietary supplements to increase strength and muscle mass during resistance training, to reduce fatigue and to ease recovery. Mhashilkar AS et al. (2016) were revealed anti-parasitic activity of 20-hydroxyecdysone against the human filarial parasites. According to recent searches in academic databases and medical search engines (Google, www.google.com; PubMed, www.ncbi.nlm.nih.gov/pubmed; … |
SVETLANA OSIPOVA; | 2021-01-01 |
| 4 | Diagnostics of Intestinal Parasitosis in Inhabitants of Kuyavian-Pomeranian Province in Poland PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: The goal of the proposed study is to assess the prevalence of intestinal parasitic diseases in adults and children. These invasions are included to dirty hand diseases (per os invasions), therefore it applies mainly preschool children. |
PAWEŁ SUTKOWY; | 2018-02-17 |
| 5 | Epidemiology of Chronic Diarrhea Among Children Admitted to Gastroenterology Unit at Assuit University Children Hospital PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Chronic diarrhea is defined as stool volume of more than 10g/kg/day in toddlers/infants and greater than 200 g/day in older children that lasts for 14 days or more. Chronic diarrhea has many of causes can calcified as infectious & noninfectious causes. – Infectious causes as: – Escherichia coli, Giardia Lamblia, tuberculosis, Clostridium difficile & Shigella. – Noninfectious causes as(Abnormal digestive processes- Nutrient Mal -absorption- Immune/ inflammatory- Defects of electrolyte And metaboliteTransport- Motility disorders- Diarrhea associated With exogenous substances) There are four basic pathophysiological categories of diarrhea: as ( osmotic diarrhea- secretory diarrheas- motility related diarrhea- Inflammatory diarrhea) |
MOUSTAFA ABD ELLATIF; | 2017-08-22 |
| 6 | Randomized, Dose-finding, Double-blind, Placebo-controlled, Crossover Gluten Challenge Trial in Subjects With Nonceliac Gluten-sensitivity PF:4 Related Papers Related Patents Related Grants Related Experts View Highlight: An emerging problem in clinical practice is how to manage the growing number of patients who experience symptoms related to the ingestion of gluten-containing foods gluten and in whom celiac disease has been ruled out. These patients most frequently report gastrointestinal symptoms such as diarrhea, abdominal discomfort or pain, bloating, flatulence, but also extraintestinal symptoms, including headache, lethargy, attention-deficit/hyperactivity disorder, ataxia, or recurrent oral ulceration. This heterogeneous syndrome, which has been reported to improve or even disappear after gluten withdrawal and to relapse after gluten challenge, … |
ANTONIO DI SABATINO; | 2017-06-13 |
| 7 | Treatment of Giardia Lamblia Infections in Children: Randomized Open-labeled Trial Comparing Rectal Metronidazole With Oral Tinidazole Related Papers Related Patents Related Grants Related Experts View Highlight: This study investigates the efficacy and safety of rectally administered metronidazole for pediatric Giardia lamblia infection, as well as the acceptance of this treatment regimen by patients/caregivers. The investigators hypothesize that rectal metronidazole is non-inferior to single-dose of oral tinidazole and will cure at least 72% of patients, a well as will be tolerated as good as tinidazole. |
SVETLANA KOSTJUKOVITS; | 2016-12-01 |
| 8 | Phase IIa Randomized, Single-Blinded, Placebo-Controlled Clinical Trial of The Reprofiled Drug Auranofin for GI Protozoa PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: This is a phase IIa, randomized, placebo-controlled, single-blinded superiority treatment study in males and non-pregnant females, 18 to 65 years of age who are in good health. This study is designed to compare placebo to once daily doses of 6mg auranofin for adults with amebiasis or giardiasis. A sample size of 68 subjects enrolled with amebiasis (34 per arm) and 68 with giardiasis (34 per arm); … |
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES NIAID | 2016-11-06 |
| 9 | Fecal Microbiota Transplantation in Refractory Clostridium Difficile Colitis PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant stool from healthy donors to treat recurrent C. difficile colitis by incorporating the stool into capsules that are administered by the oral route. |
GARY M COX; | 2016-04-01 |
| 10 | Chronic Fatigue Syndrome and Abdominal Symptoms After Giardia Infection: Clinical Evaluation, Biomarkers, Risk Factors and The Effect of Intervention PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: A giardiasis outbreak in Bergen has given us the opportunity to approach two basic research questions of national and global importance: – Studying the pathoimmunology of giardiasis in a natural setting, and following the genetic and immunological responses leading to recovery or persistent disease and sequelae. – Studying the two disease entities FGID and CFS when induced by acute giardiasi and their risk factors. – Interventional cognitive behavioural therapy is the only intervention documented to have significant effect on CFS outcome, … |
NINA LANGELAND; | 2009-03-01 |
| 11 | Exploratory Study to Evaluate The Effect of L-isoleucine Supplemented Oral Rehydration Solution in The Treatment of Acute Diarrhoea in Children and in Inducing Innate Immunity PF:2 Related Papers Related Patents Related Grants Related Experts View Highlight: Efforts are continuing to improve the efficacy of oral rehydration solution in terms of reducing the severity (stool volume) and duration of diarrhoea (enhancement of recovery). Antimicrobial peptides, produced by the epithelial cells, represent an important component of the innate immunity of all epithelial surfaces of the body including intestine. Induction of expression of antimicrobial peptides on epithelial cell surface, may thus hasten recovery from infectious diarrhoea. Isoleucine is an essential amino acid that is easily available and not very expensive, … |
INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH BANGLADESH | 2007-07-01 |
| 12 | Malabsorption As A Cause of Iron Treatment Failure in Infants – A Clinical Observational Study PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: Infants should receive prophylacatic iron supplementation since age 4 months till one year. Patients suffering from malabsorption, mainly Giardia infestation may develop iron deficiency resistent to further iron treatment. The purpose of this study is to assess the incidence of malabsorption in those infants and to examine the results of empiric treatment with metronidazole. |
CARINA LEVIN; | 2006-05-01 |
| 13 | Study of Patients With Parasitic Infections of The Gastrointestinal Tract PF:3 Related Papers Related Patents Related Grants Related Experts View Highlight: This protocol offers diagnosis and standard medical treatment for various parasitic gastrointestinal infections. Gastrointestinal parasites are either worms (helminths) or one-celled animals called protozoans which live in the human intestines. Often, parasitic infections do not cause illness. In these cases, drug treatment is not indicated, because treatment can have adverse side effects. Patients will be examined for their immune responses, correlation between the number of parasites and disease, and other studies. Individuals with known or suspected parasitic diseases of the gastrointestinal tract, including amebiasis, giardiasis, hookworm, strongyloidiasis, trichuriasis, pinworm, tapeworm, trichinosis, clonorchis, opisthorchis, coccidiosis, paragonimiasis, … |
THEODORE E NASH; | 1977-05-23 |