Clinical Digest: Recent Clinical Trials on Plastic Surgery (2026-04)
To assist researchers and healthcare practitioners in staying up-to-date with the latest advancements in clinical research, the Clinical Digest Team has compiled a comprehensive list of recent clinical trials related to Plastic Surgery. These trials are organized by their release dates for your convenience. (Last updated on: 2026-04-06)
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TABLE 1: Clinical Digest: Recent Clinical Trials on Plastic Surgery (2026-04)
| Clinical Trial | Contact(s) | Updated | |
|---|---|---|---|
| 1 | Evaluating The Effect of CO2Lift Pro® Carboxy Gel on T-Junction Breakdown Rates After Breast Reduction Surgery: A Feasibility Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this pilot study is to determine the feasibility of a larger randomized controlled trial evaluating CO₂Lift® Pro Carboxy Gel to reduce wound breakdown after bilateral breast reduction in adult female patients undergoing elective bilateral breast reduction surgery. The main question it aims to answer is: Is it feasible to recruit, retain, … |
JUSTIN YEUNG; | 2026-02-13 |
| 2 | Feasibility of Imaging Breast Implants With A Transmission-based Transmission Scanner PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this clinical trial is to assess whether microwave scans can depict the presence of implants in the breast in women with existing breast implants that were surgically placed at least 6 months ago. The main questions it aims to answer are: 1. Can a microwave imaging device effectively scan a breast containing implants? 2. Can the presence of implants be identified in a microwave scan? 3. Can the microwave scans of the left and right breasts be compared to assess whether similarity is observed? |
ELISE FEAR; | 2026-03-23 |
| 3 | Evaluation of Emotional Responses Using The I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics. Individuals with dentofacial abnormalities often experience difficulties with chewing, biting, and social interaction, which may negatively impact psychological well-being and overall quality of life. Orthognathic surgery must be combined with orthodontic treatment before and after the operation to ensure optimal functional and aesthetic outcomes. The conventional orthodontics-first approach involves prolonged preoperative orthodontic treatment (typically 12-24 months, … |
ZYGIMANTAS PETRONIS; | 2026-03-17 |
| 4 | Opioid Avoidance In Surgery Through Integrating Suzetrigine: Post-Operative Care Phase Pilot PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This prospective, single-arm feasibility study will evaluate postoperative pain control, opioid use, and early recovery outcomes in adult patients undergoing elective outpatient facial plastic surgery who receive suzetrigine as part of their standard postoperative analgesic regimen. |
DEANNA C. MENAPACE; | 2025-12-02 |
| 5 | The Effect of Bilateral Rhomboid Intercostal Block on Postoperative Analgesia and Opioid Consumption in Patients Undergoing Bilateral Breast Implant Surgery: A Prospective Controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This prospective, randomized, single-center, study aims to evaluate the postoperative analgesic effectiveness of bilateral Rhomboid Intercostal Block (RIB) in patients undergoing elective bilateral breast prosthesis surgery. Effective postoperative pain management is essential to improve patient comfort and reduce opioid consumption. Eligible patients aged 18-65 years with ASA physical status I-II will be randomly assigned to either receive ultrasound-guided bilateral RIB block in addition to standard general anesthesia or undergo surgery without any regional block (control group). All patients will receive standardized general anesthesia and postoperative patient-controlled analgesia (PCA) with intravenous tramadol. The primary outcome of the study is total tramadol consumption within the first 24 postoperative hours. Secondary outcomes include postoperative pain scores at predefined time points, time to first analgesic requirement, need for rescue analgesia, incidence of nausea and vomiting, and block-related complications. The results of this study will help determine whether bilateral RIB block provides superior postoperative pain control compared to standard analgesic management alone in bilateral breast prosthesis surgery. |
KONUL KARAJA; | 2026-03-04 |
| 6 | Clinical Investigation Evaluating Medical Grade Polycaprolactone (PCL) Breast Scaffold Implantation in Conjunction With Autologous Fat Grafting for Breast Implant Revision Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The objective of this clinical trial is to generate robust data that demonstrates clinical performance and safety of a polycaprolactone (PCL) breast scaffold combined with autologous fat grafting (AFG) in women who seek a revision surgery of a breast implant used for breast augmentation. The material (PCL) has been in clinical use for many decades and is absorbable. This study follows the successful completion of a 2-year evaluation of the safety and feasibility of this technique performed by the Royal Brisbane and Women’s Hospital (ClinicalTrials.gov ID: NCT05437757). The main question it aims to answer is: Is PCL Breast Scaffold with autologous fat graft a safe and effective method of soft tissue reconstruction following breast implant revision?. Participants will: * Undergo removal of their existing silicone breast implant (if not previously removed), * Receive implantation of a PCL Breast Scaffold combined with autologous fat grafting (AFG), and * Attend follow-up visits at 1 week, 3 months, 6 months, and annually for up to 5 years for clinical assessments and questionnaires. |
OWEN UNG; | 2026-03-05 |
| 7 | Effect of Postoperative Ozonated Oil Dressing on Early Wound Inflammation After Open Mesh Inguinal Hernia Repair: A Prospective Randomized Pilot Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery. Open inguinal hernia repair is a common operation, and although infection rates are low, many patients experience redness, swelling, tenderness, … |
ALIRIZA ERDOĞAN; | 2026-02-11 |
| 8 | Long-term Follow-up Study to Evaluate The Long-term Safety and Performance of PCL Breast Scaffolds Used for Breast Implant Revision Surgery in 2021-BRV-004 PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The objective of this study is to assess the long-term safety and performance of the PCL Breast Scaffold in women who previously underwent breast silicone implant revision and received the PCL Breast Scaffold combined with autologous fat grafting (AFG) in the 2021-BRV-004 clinical trial (ClinicalTrials.gov ID: NCT05437757). In addition, this study will investigate the suitability of mammography in the subset of patients that fall into the national breast screening age category – … |
OWEN UNG; | 2026-02-03 |
| 9 | Assessment of Patient Satisfaction and Healing Outcomes With The ELIXIR MD™ Device in The Perioperative Period of Plastic Surgery PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of routine clinical practice. The study aims to describe changes in patient-reported and clinician-assessed recovery measures following elective surgical procedures. The main questions this registry aims to answer are: 1. How do patient-reported recovery outcomes, including pain, satisfaction, and perceived improvement, change over the postoperative period? 2. How do clinician-assessed indicators of recovery, such as swelling and bruising, … |
ELIXIR MD | 2026-02-17 |
| 10 | The Effect of Topical Triamcinolone Acetonide Application on Wound Healing in The Palatal Donor Site Following Free Gingival Graft Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG) surgery. A total of 36 patients with mucogingival deficiencies requiring FGG will be randomly assigned to either a control group receiving a collagen hemostatic sponge or a test group receiving topical triamcinolone acetonide at the donor site. All palatal donor areas will be protected with a periodontal dressing. Clinical assessments will be performed on postoperative days 7, 14, … |
ESRA BOZKURT; | 2026-02-13 |
| 11 | The Role of Amnion Membrane Allografts in Nipple Preservation After Nipple Sparing Mastectomy: A Double-Blinded Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The overall objective of this proposal is to conduct a randomized-controlled study to determine whether treatment with dehydrated human amnion/chorion membrane (dHACMs) allografts can improve NAC viability in patients undergoing nipple sparing mastectomy (NSM). dHACM allografts are commercially available tissue membranes with biocompatible extracellular matrix and growth factors that have been shown to improve wound healing in patients with chronic and lower extremity wounds. To date, no study has evaluated the impact of dHACMs on NAC preservation following NSM. Investigators hypothesize that subareolar surgical implantation of dHACM allografts at time of NSM will reduce NAC necrosis and improve viability. |
DUNG NGUYEN; | 2025-11-17 |
| 12 | Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis Related Papers Related Patents Related Grants Related Experts Highlight: This study will be a prospective randomized study to evaluate the effect of medrol dosepaks (oral corticosteroids) on postoperative outcomes among patients undergoing rhinoplasty by Facial Plastic Surgeons at Vanderbilt. Outcomes will include postoperative pain, nausea, and patient experience, with secondary outcomes of swelling and bruising. Methylprednisolone is an oral corticosteroid that has been shown in multiple RCTs and is used extensively that it can significantly reduce postoperative swelling and bruising in postoperative rhinoplasty patients, however, we have not examined if those effects extend to their pain ratings, nausea, … |
PRIYESH PATEL; | 2025-11-18 |
| 13 | Efficacy of Platelet Rich Plasma Injection for Vocal Fold Sulcus, Scar and Atrophy PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: a study to asses safety and efficacy of platelet rich plasma injection in some types of vocal fold problems such as sulcus and atrophy to see the improvement in patient voice and its impact on patient quality of life with a good period of follow up |
AYA ESAM SHARKAWY; | 2026-01-20 |
| 14 | Comparative Study of Ziplyft Treatment Vs. Traditional Blepharoplasty for Upper Eyelid Rejuvenation PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study will compare two surgery techniques used for upper eyelid (eyelift) surgery: traditional surgery and a newer method called Ziplyft (a non-powered, hand-held clamp). This study will use a split-face design, meaning one eyelid will be treated with the traditional surgery method and the other with Ziplyft, allowing a direct side-by-side comparison. The objectives of the study are to compare Ziplyft treatment vs. traditional surgery by evaluating bruising, wound closure and incision, surgery case time, and subject/surgeon surveys. |
SUMEET JINDAL; | 2025-11-26 |
| 15 | The Effect of Tranexamic Acid on Drainage Volume and Time to Drain Removal in Reduction Mammaplasty Patients PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery. Participants will be randomly assigned to receive either intravenous TXA or no TXA during surgery. Additionally, one breast will receive TXA through the surgical drain, while the other will receive saline. This approach allows to compare the effects of TXA on fluid buildup and healing. The goal is to improve recovery and reduce complications after breast reduction surgery. |
KATHERINE CARRUTHERS; | 2026-01-16 |
| 16 | Comparison of Outcome Between Grisotti Flap Versus Reverse Mirror Grisotti Flap for Central Quadrant Breast Tumors PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Breast conservation surgery is equivalent to mastectomy for early stage breast cancer patients. Central quadrant tumours can be treated with various oncoplastic techniques with a satisfactory aesthetic outcome and low morbidity. Grisotti flap and reverse mirror grisotti flap are the favourable viable surgical options for central quadrant breast tumours. our hypothesis is that there is a difference in the outcome between Grisotti versus Reverse Mirror Grisotti flap in centrally located breast cancers. |
AQEELA SHIRAZI; | 2025-12-18 |
| 17 | Autologous Adipose-derived Stromal Vascular Fraction Therapy for Refractory Endometrial Infertility PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is to initially explore the efficacy of adipose-derived stromal vascular fraction (AD-SVF) therapy in the treatment of refractory endometrial infertility. |
YALI HU; | 2025-11-18 |
| 18 | Cartilage Remodeling Using Low-Temperature Radiofrequency for Facial Reconstruction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricular cartilage for use in cosmetic and functional septorhinoplasty. The investigators hope to answer the following questions: 1. How many LTRF treatments are needed to achieve the desired shape in a given cartilage specimen 2. How does an LTRF treatment quantitatively affect both length and angulation of a cartilage specimen 3. How does physician satisfaction with cosmetic outcome compare to cases treated with existing septorhinoplasty techniques 4. How do changes in patient reported measures of nasal obstruction (NOSE score) pre- and post-surgery compare to cases treated with existing septorhinoplasty techniques 5. Does using LTRF during septorhinoplasty significantly increase total operative time 6. Are rates of adverse events when using LTRF different from cases treated with existing septorhinoplasty techniques Participants will complete the NOSE questionnaire at their pre-operative visit. Participants undergoing cosmetic septhorhinoplasty will also be photographed in standard fashion for facial analysis. During scheduled septorhinoplasty surgery, the Vivaer LTRF device will be used to reshape nasal and/or auricular cartilage ex-vivo prior to reimplantation at the discretion of the Principal Investigator in order to optimize functional and cosmetic outcome. Participants will follow up at approximately 1 week and 1 month after surgery. At 1 month, the NOSE questionnaire will be readministered to all participants, and cosmetic patients will be photographed again. |
TAHA SHIPCHANDLER; | 2025-12-01 |
| 19 | Safety and Outcomes of Ellacor® Micro-Coring Technology® in Fitzpatrick Skin Types I-VI, Including Patients Receiving Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs): A Case Series PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The main purpose of the study is to collect information about how the device functions in a variety of treatment areas and skin types and to find out what changes, if any, occur in the skin treated with the study device compared to the skin that wasn’t treated including patients receiving GLP-1’s, a class of medications that mimic a natural hormone to help control blood sugar and support weight loss. The study will also evaluate side effects that occur with this treatment, if any. Standardized 2D Imaging will be used to quantify reduction of wrinkle severity |
STEVEN WILLIAMS; | 2025-12-31 |
| 20 | Minimally Invasive Post-Traumatic Craniofacial Soft Tissue Regeneration: Validation of Safety and Efficacy of Staged Approach Using Autologous Fresh Fat Grafting Followed By Autologous Cryopreserved Fat Grafting PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this clinical trial is to validate the safety and effectiveness of a two-stage approach for minimally invasive craniofacial soft tissue reconstruction using autologous fat grafting in wounded service members and veterans. The main questions it aims to answer are: 1. Will treating subjects with post-traumatic craniofacial deformities using fresh fat grafts, followed by a second treatment 3 months later with cryopreserved fat stored at -80°C, … |
J. PETER RUBIN; | 2025-10-22 |
| 21 | Hybrid Autologous Breast Augmentation in Mastopexy With Internal BRA Fixation; Using Local Breast Tissues and Fat Grafting PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The breast is a very important organ for women’s self-esteem and is regarded as a symbol of femininity. Deviations from normal size, shape, and symmetry are interpreted as unattractive and a sign of aging. Far from posing merely a cosmetic problem, such deviations deeply disturb both the patient’s perception of her body and her emotional balance. The first breast surgeries started as early as the 6th century, … |
ALAA HASSAN M. ELHAWARY; | 2025-10-02 |
| 22 | A Prospective, Randomised, Split-Body, Controlled, Non-Inferiority Clinical Study on The Scar Healing Effects of ChitoCare Medical Scar Healing Gel in Women Undergoing Breast Reduction or Mastopexy Surgery (CHITOSCAR) PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Patients undergoing breast reduction or mastopexy surgery will be screened and recruited for participation in the study. Eligible patients will act as their own control with one breast receiving the active intervention (ChitoCare® medical Scar Healing Gel) and the other receiving standard of care (Amoena CuraScar Mammilla Circles Silicone Scar Patch and Amoena CuraScar Anchors Silicone Scar Patch). The active and control interventions will be applied for six months, and participants will be followed for up to 12 months. The scar properties of each breast will be assessed at study initiation (Day 0) and at study visits at 3, 6, … |
PRIMEX EHF | 2025-08-14 |
| 23 | Anterior Repositioning Splint With or Without Arthrocentesis and Platelet-rich Plasma Injection In TMD Patients With Anterior Disc Displacement With Reduction: A Randomized Controlled Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study will be conducted to assess the effect of anterior repositioning splint and arthrocentesis with platelet-rich plasma injection compared to anterior repositioning splint only, in TMD patients with anterior disc displacement with reduction |
MOHAMED SALEH THABIT ALI; | 2025-08-11 |
| 24 | The LYMPH Trial – Surgical Versus Conservative Complex Physical Decongestion Therapy for Chronic Breast Cancer-Related Lymphedema: A Pragmatic, Randomized, Multicenter Superiority Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Title: The LYMPH Trial – Microsurgical versus Conservative Therapy for Breast Cancer-Related Lymphedema Purpose of the Study: The LYMPH trial compares two treatments for chronic breast cancer-related lymphedema (BCRL)-a condition where fluid builds up and causes swelling, usually in the arm, after breast cancer treatment. The study is testing whether microsurgical treatments (lymphatic surgery) are more effective than the current conservative therapy (called CDT) in improving quality of life for women with this condition. What is BCRL? After surgery or radiotherapy for breast cancer, … |
UNIVERSITY HOSPITAL GHENT | 2025-07-01 |
| 25 | Autologous Adipose Cells Therapy PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Autologous Adipose Cell Therapy is a series of process designated to address the demerits of the traditional autologous fat grafting and dermal fillers, while enhancing the versatility and aesthetic outcomes. In this study, the goal is to evaluate the safety and efficacy of Autologous Adipose cell Therapy for skin rejuvenation and hair improvement in human application. |
ABDOLLAH M. MALEKZADEH; | 2025-05-23 |
| 26 | Single-Stage Prepectoral Placement of Textured Implants Using A Polyester Mesh Endoprostheses With Fluoropolymer Coating in Patients With Breast Cancer PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This study aims to evaluate the efficacy of using a polyester mesh endoprosthesis with a fluoropolymer coating in reducing postoperative complications, particularly protrusions, following subcutaneous mastectomy with simultaneous prepectoral placement of textured breast implants in women with breast cancer |
LAISAN SHAIKHELISLAMOVA; | 2025-09-22 |
| 27 | The BEACON Trial: Diagnostic Tools for Breast Lymphedema After Treatment for Breast Cancer PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this observational study is to learn if participants agree to take part in the study, if the methods we are using for the study are feasible for the participants and the researchers, and to study how well two tools (tissue dielectric constant and ultrasound) measure breast edema after breast conserving surgery for breast cancer. Participants who agree to be in the study will be asked to come in for one appointment of approximately two hours. All data will be collected during this one visit. Participants will be asked to fill out two questionnaires regarding their symptoms, … |
CHERYL BRUNELLE; | 2025-07-16 |
| 28 | A Prospective, Multicenter, Controlled Clinical Study of 3D-printed Biodegradable Breast Implants for Breast Restoration PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this clinical trial is to evaluate the cosmetic effect of breast reconstruction based on 3D-printed biodegradable material breast implants in personalized breast reconstruction and the quality of life of patients, … |
XIJING HOSPITAL | 2025-06-06 |
| 29 | Pseudomonas Aeruginosa Injection Combined With Polyvinylpyrrolidone-Iodine in Immediate Breast Reconstruction Surgery With Implants：a Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Brief Summary This study hypothesizes that in immediate breast reconstruction following tumor resection, the application of inactivated Pseudomonas aeruginosa preparation (PAP) may reduce infection rates by decreasing postoperative drainage output and shortening drainage tube removal time. Additionally, the local aseptic inflammation induced by PAP may promote fibrous capsule formation around the implant, shorten postoperative shaping time, and improve patients’ quality of life and satisfaction. To test this hypothesis, … |
JIANYI LI; | 2026-03-10 |
| 30 | Effect of Collagen Supplements on Dermal Collagen Content Within Skin Biopsies of Plastic Surgery and Metabolic Bariatric Surgery Patients PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This study aims to evaluate the effects of oral collagen supplementation on dermal collagen content in skin biopsies of patients undergoing abdominoplasty. Using a randomized controlled trial (RCT) design, participants from metabolic bariatric surgery (MBS) and plastic surgery groups will receive either collagen supplements or a placebo for several weeks. Biopsies will be collected pre-intervention and during surgery to compare collagen levels between groups and to baseline. The primary objective is to determine if collagen supplementation significantly enhances dermal collagen deposition compared to placebo and initial levels. |
MOHAMED HANY ASHOUR; | 2026-02-17 |
| 31 | Prevention of Postoperative Complications By Negative Pressure Therapy After Complex Breast Cancer Surgery: A Prospective Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: There is little scientific data concerning the use of negative pressure therapy after immediate breast reconstruction. That strategy of treatment-reconstruction has expanded increasingly since the last years. The current literature reports only 3 studies on the use of preventive negative pressure therapy in oncologic breast surgery. Moreover, all three are retrospective, case-control studies with serious limitations. The largest published series reports a reduction in the overall complication rate from 15.9% to 8.5%, and a significant reduction in several criteria: infection, scar dehiscence and necrosis. However, the study presents significant biases, with non-comparable populations in terms of comorbidities, surgical procedure performed, … |
PIERRE BURNIER; | 2026-02-05 |
| 32 | A Phase 1 Controlled Study to Evaluate The Safety and Tolerability of Intradermal Administered Purified Exosome Product (PEP) in Healthy Adults Related Papers Related Patents Related Grants Related Experts Highlight: This clinical trial aims to characterize the safety, tolerability, and histological profile of PEP (Purified Exosome Product) when injected into the hypodermis of healthy adults. The main questions this study aims to answer are: Is PEP safe and tolerable when injected into the hypodermis of healthy adults? Subjects will serve as their own control and researchers will compare PEP to Control to see if PEP is safe. |
JOHN H JOSEPH; | 2025-12-26 |
| 33 | A Single-center, Single-arm Prospective Study to Evaluate Capsulase for Prevention of Capsular Contracture in Postmastectomy Patients Undergoing Implant-based Reconstructions PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The study plans to evaluate capsular contracture at 1-year follow-up in postmastectomy patients receiving immediate implant-based reconstruction and Capsulase® supplementation in the postoperative period. These data are compared with historical data of capsular contracture in patients not receiving any food supplementation postoperatively. Aim of the study is to collect preliminary data to support Capsulase® supplementation in the postoperative period to prevent capsular contracture. |
FRANCESCA DE LORENZI; | 2026-01-05 |
| 34 | Bilateral Ultrasound-Guided Erector Spinae Plane Block or Serratus Anterior Plane Block For Postoperative Analgesia in Breast Reduction Surgery: A Prospective, Randomized and Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: the aim of the study compare the analgesic effect of erector spinae block and serratus anterior block in breast surgery |
LEYLA KILINC; | 2026-02-18 |
| 35 | Safety And Effectiveness Of FlexHD® Pliable Acellular Dermal Matrix In Implant-Based Breast Reconstruction PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Prospective, multi-center, single-arm clinical study in females undergoing immediate implant-based breast reconstruction using a pre-pectoral technique |
MUSCULOSKELETAL TRANSPLANT FOUNDATION | 2025-04-02 |
| 36 | Prospective Evaluation of Efficacy of Tumescent Steroid Infiltration in Mandibular Third Molar Surgery: A Split Mouth Randomized Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of this study is to evaluate the efficacy of tumescent solution on post operative sequalae in patients treated for surgical removal of impacted lower third molar. The objectives are Primary Objective 1\. To evaluate post-operative pain severity after surgical removal of impacted lower 3rd molar under Lidocaine 2% with adrenaline with and without Tumescent steroid infiltration. Secondary objectives 1. To evaluate post-operative trismus after surgical removal of impacted lower 3rd molar under Lidocaine 2% with adrenaline with and without Tumescent steroid infiltration 2. To evaluate post operative swelling after surgical removal of impacted lower 3rd molar under Lidocaine 2% with adrenaline with and without Tumescent steroid infiltration |
POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK | 2026-02-27 |
| 37 | Oncological Safety of Oncoplastic Breast Surgery in Multicentric Breast Retrospective Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of the study is to evaluate Oncological safety of oncoplastic breast surgery in multicentric breast cancer |
ALSHYMAA ABD-ELHARS EBRAHEM; | 2025-04-17 |
| 38 | The Impact Of Media, Socioeconomic And Psychological Factors On The Adoption Of Aesthetic Technology And Cosmetic Surgery Among Women In Punjab, Pakistan PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This study titled The Impact of Media, Socioeconomic and Psychological Factors on the Adoption of Aesthetic Technology and Cosmetic Surgery Among Women in Punjab, Pakistan explores how various external and internal influences affect Pakistani women’s decisions to undergo cosmetic procedures. With the rising trend of aesthetic treatments driven by modern beauty standards and social media exposure, the study investigates how psychological motivations, economic conditions, and media content shape these decisions. The increasing accessibility of non-invasive cosmetic options has made such procedures more common across different socio-economic groups. |
MUHAMMAD NAVEED BABUR; | 2025-07-03 |
| 39 | Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques: A Randomized Controlled Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study has been initiated to evaluate the question, What is the best way to protect the palate after a gum graft is removed? The overall objective is to determine if there is a difference in PROMs of donor site healing using different palatal post-operative protection techniques. |
RAFAEL AMORIM CAVALCANTI DE SIQUEIRA; | 2025-03-24 |
| 40 | The Effect of Nurse-Led Coaching Program on Self-Care Agency and Quality of Life in Reconstructed Breast Cancer Patients PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The primary objective of this clinical study is to examine the effects of a nurse-led coaching program on self-care agency in breast cancer patients who have undergone reconstruction. The secondary objective is to determine the opinions of patients who participated in the nurse-led coaching program for breast reconstruction surgery. Primary questions the study aims to answer are: 1. Is there a difference in self-care agency between breast reconstruction patients who received a nurse-led coaching program and those who did not? The secondary objective of this clinical study is to examine the effects of a nurse-led coaching program on quality of life in breast cancer patients who have undergone reconstruction. The secondary questions the study aims to answer are: 2. Is there a difference in quality of life between breast reconstruction patients who received a nurse-led coaching program and those who did not? The researchers will compare whether there are differences in self-care agency and quality of life between breast cancer patients who received a nurse-led coaching program (intervention group) and those who did not (control group). Participants: * Patients who meet the inclusion criteria will be informed of the study’s purpose during their postoperative hospital stay, and their informed consent will be obtained. Patients who agree to participate will complete an Introductory Information Form, the Self-Care Agency Scale, and the EORTC QLQ-C30 and QLQ-BR-42 Quality of Life Scales. * After completing the pre-test measurements, the researchers will randomly assign patients to either the control or intervention groups using a random number table. * Patients in the intervention group will receive a routine debriefing on the day of discharge and a total of nine coaching sessions, scheduled weekly for the first 6 weeks and biweekly for the following 6 weeks. These sessions will be conducted via online meeting. * Patients in the control group will receive a routine debriefing only on the day of discharge. * Post-test measurements will be administered to both groups at 12 weeks post-operatively. |
SEVIL GÜLER; | 2026-01-21 |
| 41 | Comparison of Serratus Plane Block and Rhomboid Intercostal Plane Block for Postoperative Analgesia in Patients Undergoing Breast Reduction Surgery: A Randomized Clinical Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This prospective, randomized clinical study aims to compare the analgesic efficacy of serratus plane block (SPB) and rhomboid intercostal plane block (RIPB) for postoperative analgesia in patients undergoing elective bilateral breast reduction surgery under general anesthesia. All patients will receive standardized general anesthesia. Before induction of anesthesia, while patients are awake, Group SPB will receive an ultrasound-guided serratus anterior plane block and Group RIPB will receive an ultrasound-guided rhomboid intercostal plane block. Postoperative analgesia will be maintained with intravenous patient-controlled analgesia (PCA) with opioids. Primary outcomes include postoperative pain scores and opioid consumption at 1, 6, 12, … |
KONUL KARAJA; | 2025-11-19 |
| 42 | A Study to Evaluate The Safety and Effectiveness of AlloMend® Acellular Dermal Matrix Used in Post Mastectomy Pre-Pectoral Breast Reconstruction and Followed for Up To 12-Months Post-Operatively PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This retrospective, single-site study will provide information regarding the efficiency of AlloMend® Acellular Dermal Matrix allograft in Pre-Pectoral Breast Reconstruction surgery following a single or double mastectomy. |
ALLOSOURCE | 2025-11-21 |
| 43 | Implant-based Breast Surgery and Reconstruction Following Bariatric Surgery: An Observational Register-based Study on Prevalence and Risk Factors for Surgical Complications PF:9 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this national registry-based study is to investigate the prevalence of reconstructive breast surgery and risk factors for surgical complications in women who have had weight loss surgery previously. The main questions it aims to answer are: 1. What is the perceived need for breast implants after weight loss surgery, described as the proportion who have breast implants, and what characteristics, in terms of demographics and surgical details, do the operated women have? 2. In women who have breast enlargement or breast enlargement combined with a lift, … |
EMMA HANSSON; | 2025-07-16 |
| 44 | A Prospective, Randomized, Controlled, Multi-Center Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Prospective, randomized, controlled study to assess the safety and effectiveness of GalaFLEX LITE™ Scaffold in revision surgery for reduction of capsular contracture recurrence and/or malposition in implant-based breast augmentation patients versus patients undergoing conventional revision surgery with no supportive matrix or acellular dermal matrix (ADM). Subjects will be randomized 2:1 to receive either GalaFLEX LITE™ Scaffold or standard care (no ADM or matrix placement). This study is designed using an adaptive approach. The number of the treated breasts will range between 250 and 530. |
OREN TESSLER; | 2026-03-10 |
| 45 | The Application of Ultrasonic Measurement of Optic Nerve Sheath Diameter in Liposuction Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The main purpose of this study is to investigate the effect of changes in Optic Nerve Sheath Diameter (ONSD) measured at different operating position during Liposuction Surgery. Optic nerve sheath diameter (ONSD) has been shown to be a noninvasive indicator for monitoring intracranial pressure changes. The use of anesthetic drugs will reduce the intracranial pressure. However, prone position and large fluid infusion can still lead to increased intracranial pressure. The investigators hypothesized that during sedation and analgesia anesthesia, patients in prone position had higher ONSD. |
XU WENLI; | 2025-09-30 |
| 46 | Standardization of A New Psychophysical Olfactory Test, TODA2 PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Recruitment of patients consulting the IUFC for another pathology unrelated to an olfactory disorder: Interview and clinical examination and Passing the 2 olfactory tests for 30 voluntary’s patients, a second consultation of 15 minutes including the time of the test within 7 days after the 1st |
CLAIR VANDERSTEEN; | 2025-04-22 |
| 47 | The Impact of Nutritional Optimization to Enhance Postoperative Outcomes Using The R-Support Supplements PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of this pilot study is to evaluate the potential benefits of nutrient supplementation on post-operative recovery for patients undergoing certain types of surgery, compared to those who do not receive such supplementation. The multi-center study will be conducted in Belgium and the Netherlands at UZ Brussel, Delta CHIREC, and Zuyderland Medical Center. The pilot study will serve as a precursor to a randomized controlled trial and will include 200 patients. Participants must be classified as ASA I or II, aged between 18 and 65, and undergoing abdominoplasty, breast reduction, breast reconstruction through a DIEP-flap, … |
LETIZIA GEORGIOU; | 2025-12-31 |
| 48 | The IMpact of 3D Surface Imaging and Simulation on Shared Decision Making in Immediate Breast REconstruction And The Measurement of The EffectS of RadioTherapy PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Patients who require a removal of a breast (mastectomy) for breast cancer or future risk reduction often have immediate breast reconstruction (IBR). This can be performed using either an implant or the patient’s own body fat to recreate the breast shape. Patients can find it difficult to imagine their own post-surgery appearance. Using 3D surface imaging (3D-SI) can change a patient’s pictures to show them how they might look after surgery, … |
JENNIFER RUSBY; | 2025-08-22 |
| 49 | A Randomized Controlled Trial Comparing Periareolar Excision Versus Pull-Through Techniques in Simon Grade I-IIb Gynecomastia: A Phenotype-Dependent Outcome Analysis PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This prospective randomized controlled trial compares periareolar excision and pull-through techniques in 64 patients with Simon Grade I-IIb gynecomastia. Patients were randomized 1:1 and followed for 6 months. The primary outcome was total patient satisfaction measured using the Rasch-transformed BODY-Q Chest Module. Secondary outcomes included anthropometric measurements, recovery parameters, complication rates, and blinded aesthetic evaluation. A formal interaction analysis assessed whether surgical superiority differed according to disease severity. |
AHMED AOUF; | 2026-03-20 |
| 50 | Low Dose Magnesium Sulphate in Nasal Surgery PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This clinical trial aims to compare Patients who receive propranolol 1-2 mg to Patients who receive propranolol 1-2 mg in addition to magnesium sulphate infusion 10 mg/kg to see if IV magnesium can stability mean arterial blood pressure and heart rate in patients undergoing nasal surgeries as well as the quality of postoperative analgesia, degree of sedation mean arterial blood pressure and HR will be recorded intraoperative and Participants will be asked to rate the pain at the first, second, fourth, sixth and 24th postoperative hour using the VAS score. – … |
RANIA MAHER HUSSIEN; | 2025-01-31 |
| 51 | The Efficacy of Amnion Chorion Allograft in Management of Type 1 Gingival Recession. (Randomized Clinical Trial) PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: the main goal of this clinical trial is to test the efficacy of amnion Chorion allograft in managing gingival recession. The main questions it aims to answer are: Is it effective in treating gingival recession, and how it compares to connective tissue graft. |
MINA GERGES; | 2025-02-01 |
| 52 | NovoX® Cup As Primary Dressing After Breast Reduction: An Intra-individual Comparison Between Standard of Care and Oxygen-enriched Olive Oil Bra Cup PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Breast reduction is one of the most frequently performed plastic surgeries. Studies have shown that breast reduction surgery significantly improves the patients’ suffering and leads to a better health-related quality of life.However, as in every surgery, there can be complications. Wound disorders, such as open wounds and skin loss account for the most commonly encountered postoperative complications. NovoX® Cup is a new single-use wound dressing that is shaped cupular in order to tightly adapt to the breast anatomy. It is internally coated with oxygen-enriched oil releasing reactive oxygen species and is free from active pharmaceutical ingredients. It is intended, … |
LARS-PETER KAMOLZ; | 2025-04-10 |
| 53 | Different Methods of Tranexamic Acid Application in Controlling Perio Operative Bleeding in Gynecomastia PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Different Methods of Tranexamic Acid Application in Controlling Peri-Operative Bleeding in Gynecomastia Surgery |
AMJAD AHMED QASIM AL-GUBARI; | 2025-04-20 |
| 54 | Safety and Efficiency of Electrocautery De-Epithelization in Mammoplasty PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of this study is to evaluate safety and efficiency of electrocautery de-epithelization in mammoplasty. |
MOHAMED HAMDY ELGHAZALY; | 2025-03-24 |
| 55 | Inonu University Clinical Research Ethics Committee PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The investigators will evaluate the findings related to pain and bleeding, quality of life after surgery, and wound healing in participants who received injectable platelet-rich fibrin (i-PRF) and low-dose laser therapy to the palatal region after free gingival graft (FGG) surgery, compared to participants who did not receive any medication/active substance other than surgery. The investigators aim to evaluate whether i-PRF and low-dose laser treatments are superior to each other and to participants who did not receive any medication/active substance. The investigators predict that i-PRF and low-dose laser therapy will accelerate wound healing, reduce postoperative pain, … |
ESRA BOZKURT; | 2024-12-01 |
| 56 | A Prospective, Multi-center, Observational, Non Comparative, Post-marketing Surveillance Study to Obtain Clinical Outcome Data on The Nagor PERLE Range of Silicone Breast Implants When Used in Breast Implantation PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Patients can undergo breast implant surgery for multiple reasons; cosmetic and reconstructive being the primary indications. In order to confidently state safety and due to strict regulation on medical devices it is important to maintain a record of safety and performance with all medical implants. This study is designed to collect data on a new generation of smooth mammary implants to assess the long term performance and safety data on this type of gel-filled mammary breast implant. The two main complications of breast implants are capsular contracture and rupture; … |
NABILA NASIR; | 2025-07-11 |
| 57 | The Additive Analgesic Effects of Transversus Abdominis Plane Block in Abdominoplasty Under Spinal Anaesthesia: A Randomized Controlled Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The primary outcome is the time to first request of opioid analgesia. The secondary outcomes are intraoperative analgesic needs, incidence of conversion to general anaesthesia, the total opioid dose in 24 hours, Visual analogue scale (VAS) scores at 2, 4, 6, 12, and 24 hours postoperatively, and the incidence of postoperative side effects (nausea, vomiting, hypotension, bradycardia, and pruritic). |
ADEL ALI HASSAN; | 2025-04-16 |
| 58 | Comparison of Deep Serratus Plane Block With Deep Serratus Plane Block+Pectointercostal Plane Block PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: ASA I-II female patients aged over 18 who will undergoing breast reduction surgery will recruit to the study. Patients will divide into 2 groups. Deep serratus plane block will perform with 0,25 %bupivacaine 20 ml at the midaxillary 5. rib, bilaterally for Group I. At Group II, deep serratus plane block ( 0,25 %bupivacaine 20 ml) at the midaxillary 5.th rib+ pectointercostal plane block (0,25% bupivacaine 15 ml) at 4-5.th intercostal space will perform bilaterally . General anesthesia with sevoflurane and remifentanil will perform to the all patients. Postoperative pain scores, … |
EBRU BIRICIK; | 2024-08-10 |
| 59 | Register of Patients With Heart Failure Who Underwent Surgery to Correct Mitral Regurgitation By Percutaneous Catheter Implantation of MitraClip on The Mitral Valve PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Multicenter observational study. The study does not involve any interventions in routine clinical practice, the choice of treatment method (including the type of medical device used and the method of surgical intervention) and the methods of examination and postoperative management of patients will not differ from the standard of care for patients requiring percutaneous transcatheter edge-to-edge mitral valve reconstruction by implantation of the MitraClip clip on the mitral valve leaflets, … |
SERGEI A BOYTSOV; | 2025-12-01 |
| 60 | Effect of The Injectable Platelet Rich Fibrin After Tonsillectomy on Wound Healing Hemostasis and Post Operative Pain PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: To evaluate the effect of injectable Prf on healing, hemostasis and pain post tonsillectomy |
SHAIMAA MOHAMED AWAD ALLAH; | 2025-05-01 |
| 61 | Serratus Anterior Plane Block: Ultrasound Guided Versus Anatomical Landmark, A Randomized Control, Non-Inferiority Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This prospective, double-blinded randomized controlled trial aims to compare the efficacy of the serratus anterior plane block (SAPB) ultrasound guided versus anatomical landmark guided for gynecomastia surgery. And to detect if the anatomical landmark technique is inferior or not to the ultrasound guided technique. We hypothesize that anatomical landmark guided SAPB is not inferior to ultrasound guided SAPB. |
WESAMELDIN ABELRAHMAN SOLTAN; | 2024-05-01 |
| 62 | Effectiveness of Complex Decongestive Therapy for The Treatment of Lymphedema in Breast Cancer Patients Who Received Lymphovenous Anastomosis Surgery: A Pilot Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Breast cancer is the most common type of cancer in women worldwide. Advances in treatment have increased survival rates, so patients must live with the complications resulting from the cancer and its treatment. One of the most common side effects is lymphedema, which can occur as a secondary effect of surgical or radiotherapy treatment. Lymphatic edema is a condition characterized by an excess of lymphatic fluid, rich in proteins, in the subcutaneous tissue, causing pain, a feeling of heaviness in the affected limb, restricted range of motion, and, in some cases, progressing to the formation of ulcers and recurrent infections; … |
CATALINA LOPERA MUÑETÓN; | 2024-12-30 |
| 63 | A Prospective Study to Evaluate The Application of EndoScell Intraoperative Cellular Probing Technology in Breast Conserving Therapy and Sentinel Lymph Node Biopsy for Early-Stage Breast Cancer PF:4 Related Papers Related Patents Related Grants Related Experts Highlight: Sentinel Lymph Node Biopsy (SLNB) is a common surgical treatment for breast cancer and a primary method for assessing the pathological status of axillary lymph nodes. Precise intraoperative detection of sentinel lymph nodes during surgery assists in timely evaluation of axillary lymph node pathology and helps in formulating further treatment strategies. Touch imprint cytology (TIC) is one of the most commonly used intraoperative detection techniques. The new intraoperative cellular detection technology, EndoScell Scanner (ES), uses an improved real-time miniaturized fluorescence microscopy system for image acquisition. The ultra-high-resolution images obtained can reach the cellular level. In previous studies, … |
JIONG WU; | 2025-04-04 |
| 64 | Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride for Postoperative Analgesia After Breast Reduction Surgery: A Prospective, Single Blind, Non-randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this research is to assess pain scores and opioid use when using Liposomal (Exparel) Bupivacaine versus Bupivacaine Hydrochloride. |
BASEL A. SHARAF; | 2025-12-15 |
| 65 | Epidemiology and Hospital Management of Patients With PROS in France: A PMSI Study PF:6 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study was to estimate the incidence and prevalence of a group of genetic disorders known as PIK3CA-Related Overgrowth Spectrum (PROS) in France. Additionally, the study aimed to characterize patients, disease management, and costs associated with PROS. This study used data from the French National Hospitals Database, Programme de Médicalisation des Systèmes d’Information (PMSI). The study period was from January 2015 to December 2022. |
NOVARTIS PHARMACEUTICALS | 2025-10-29 |
| 66 | Comparison Between US Guided Retrolaminar Block and Transversus Abdominis Plane Block for Post Operative Analgesia in Patient Undergoing Abdominal Plastic Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of the study is to compare the analgesic efficacy of Us guided retrolaminar block versus transversus abdominis plane block in patient under going abdominal plastic surgery |
HADEEL ELSAGHEER; | 2025-12-15 |
| 67 | Widening of Keratinized Tissues With An Expanded Meshed Free Gingival Graft: A Multi-center Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The overall objective of this project is to evaluate, over a period of 1 year, the outcomes of either conventional free gingival graft (FGG) or mesh-FGG to increase the width of keratinized mucosa (KM) at implant sites. |
GÖTEBORG UNIVERSITY | 2025-08-21 |
| 68 | Multicenter Randomized Clinical Trial of The Use of Cyanoacrylate in Healing and Pain in The Palatal Donor Site of Connective Tissue Grafts PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Periodontal plastic surgery has been performed successfully for a long time in the treatment of gingival recessions and mucogingival defects. Epithelial and connective tissue grafts are considered the gold standard treatment for gingival recession due to their biocompatibility and long-term stability, however they require tissue harvesting from a donor area, usually the palate, increasing patient discomfort. Various hemostatic and healing agents have been used in conjunction with suturing to speed healing and reduce complications associated with this procedure, such as bleeding and pain. These include absorbable synthetic collagen, absorbable gelatin sponges, oxidized regenerated cellulose, ferric subsulfate, and more recently, … |
JOAQUIN LOPEZ-MALLA; | 2024-05-01 |
| 69 | Use of Botulinum Toxin A in Direct Eyebrow Lift Scar: A Randomized Controlled Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups. In addition to surgery, the patients will be treated with botulinum toxin in one eyebrow and saline (placebo) in the other site. The patients participate as treatment and placebo at the same time. Assessments will be carried out through non-invasive exams. |
SUZANA MATAYOSHI; | 2026-01-01 |
| 70 | The Effect of Education Given to Patients Undergoing Rhinoplasty Surgery on Involuntary Thoughts and Recovery Quality PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: With planned trainings prepared by taking into account the needs of patients and given by nurses, levels of anxiety and involuntary thoughts can be reduced and the quality of service and recovery can be increased. In this context, this research was planned to determine the effect of preoperative education given to patients undergoing rhinoplasty surgery on involuntary thoughts and recovery quality. |
TURGUT SOHRET; | 2024-12-01 |
| 71 | The Effects of Extracorporeal Shock Wave Therapy in Different Stages of Scar Formation in Postsurgical Scars Especially After Abdominplasty and Breast Reduction PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Scars can be caused by physical trauma, surgical incisions, burn injuries and even acne. Deep cutaneous injuries induce pathological scars. Other factors, such as mechanical loading, bacterial colonization are potential factors thought to underlie human hypertrophic and keloid scar formation or contractures. The effect may include functional impairment and aesthetic disadvantages. Various non-invasive mechanical interventions of physical scar management (e.g. extracorporeal shock wave therapy or ESWT) could have a beneficial influence on wound healing and prevention of hypertrophic scars. ESWT considerably improves the appearance and symptoms of hypertrophic scars. However, … |
ULRIKE VAN DAELE; | 2025-03-06 |
| 72 | Effect of Suture Material on Postoperative Nipple Areolar Complex Widening: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This will be a single-blinded study where participants are blinded to the suture type but the surgeon will draw a random, unmarked envelope containing the designated suture type at the start of the surgery. The patient population will be all patients undergoing breast surgery at the London Health Sciences Center (LHSC) – ie. University Hospital, Victoria Hospital and the Nazem Kadri Surgical Center, and St. Joseph’s Hospital. Three (3) main procedure groups will be transgender gender-affirming top surgery, cisgender female breast reduction or augmentation (including healthy and cancer patients; subgroup analysis will be performed), … |
TANYA DELYZER; | 2024-11-01 |
| 73 | Blossom® Smart Expander Device for Tissue Expander/Implant-Based Breast Reconstruction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The conventional breast tissue expander used for breast reconstruction/ augmentation requires weekly or biweekly injections of saline through the skin and into an integrated port in the implant using a needle and syringe in order to expand breast skin, which is an in-office procedure and can be uncomfortable for patients. Blossom Smart Expander Technology, currently available on the market, … |
DUNG NGUYEN; | 2025-11-17 |
| 74 | Silicone Particles in Breast Implant Capsules: A Retrospective Monocentric Study Evaluation of Silicone Bleeding PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Breast implantation is one of the most common surgical procedures in plastic surgery. It is used to reconstruct a breast after mastectomy following cancer or to increase breast volume for aesthetic purposes. Since their introduction in the 1960s, silicone breast implants have been the subject of multiple controversies, and their safety has long been questioned. One of the initial concerns was silicone bleeding, which refers to the sweating of silicone gel through the implant’s shell. Once outside the implant, silicone particles accumulate in the peri-prosthetic capsule, … |
SOCORRO ORTIZ; | 2024-12-01 |
| 75 | Prospective Evaluation of Autologous Fat Grafting to The Face With The Use of Viality™ in Processing of Lipoaspirate PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this research is to collect data on the short and long-term effects of facial fat grafting by injectable tissue replacement and regeneration in the midfacial zone, with the use of the VialityTM system. The Viality system is a US Food and Drug Administration (FDA) cleared device. |
STEVEN COHEN; | 2025-03-13 |
| 76 | A Retrospective Study To Evaluate The Safety And Effectiveness Of AlloMend® Acellular Dermal Matrix Used In Post Mastectomy Pre-Pectoral Breast Reconstruction And Followed For Up To 6-Months Post-Operatively PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This is a single-center, retrospective study which will be used to describe and evaluate the effectiveness of AlloMend® Acellular Dermal Matrix allograft for patients that have undergone Pre-Pectoral Breast Reconstruction surgery following a single or double mastectomy. |
ALAN CHEN; | 2025-11-21 |
| 77 | The Effectiveness of Tranexamic Acid in Abdominoplasty Plastic Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The investigators prepared a novel tranexamic acid (TXA) study designed to estimate the quantity of blood loss in patients undergoing abdominoplasty surgery. This study aims to quantify blood loss during abdominoplasty with and without TXA. The central hypothesis is that TXA administration reduces blood loss and fibrinolysis in patients undergoing abdominoplasty surgery. |
MAŁGORZATA DOMAGALSKA; | 2025-11-25 |
| 78 | Evaluation of The Efficacy and Safety of A Shiitake Mushroom Oil-Soluble Extract (SMosE) on Skin Barrier Function, Sebum Regulation, and Adaptive Responses: Preclinical and Clinical Investigation PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study evaluates the biological activity, safety, and clinical efficacy of SMosE (Shiitake Mushroom Oil-Soluble Extract), a topical cosmetic ingredient developed to support skin barrier function, adaptogenic responses, and sebum balance. The investigation integrates preclinical in vitro studies, ex vivo human skin explant experiments, and a randomized, double-blind, placebo-controlled clinical trial. Preclinical models were used to explore the molecular mechanisms of action of SMosE on epidermal differentiation and barrier-related markers. The clinical phase assessed the effects of a topical formulation containing SMosE on skin hydration, transepidermal water loss, sebum production, and skin surface features in adult volunteers. |
RITAMARIA DI LORENZO; | 2025-12-19 |
| 79 | The Effectiveness of Tranexamic Acid in Breast Esthetic Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The investigators prepared a novel tranexamic acid (TXA) study designed to estimate the quantity of blood loss in patients undergoing breast esthetic surgery. This study aims to quantify blood loss during abdominoplasty with and without TXA. The central hypothesis is that TXA administration reduces blood loss and fibrinolysis in breast esthetic surgery patients. |
POZNAN UNIVERSITY OF MEDICAL SCIENCES | 2025-11-25 |
| 80 | Normal Reference Values in Han Adults of Skin Thickness and Blood Flow By High-frequency Ultrasound: A Multicenter Study in China PF:4 Related Papers Related Patents Related Grants Related Experts Highlight: In recent years, high-frequency ultrasound has become a new non-invasive tool for the diagnosis of skin diseases, aesthetic medicine and preoperative and postoperative evaluation due to its higher resolution. The purpose of this multi-center Study is to establish the normal reference values of skin thickness and blood flow parameters by high-frequency ultrasound in Chinese Han adults, and to explore the influencing factors, so as to provide quantitative reference for the evaluation of facial skin aging degree and cosmetic treatment. |
CHUNYAN MA; | 2025-09-30 |
| 81 | Safety and Efficacy of Fractional Radiofrequency for The Reduction of Surgical Scar Formation PF:2 Related Papers Related Patents Related Grants Related Experts Abstract: The study will evaluate up to 20 subjects scheduled to undergo breast reduction or breast mastectomy in which scar assessment can be made after pre-surgical treatment in a … |
VENUS CONCEPT | 2025-03-28 |
| 82 | Bridging The Healing Gap: A Single-Blind Clinical Trial Assessing The Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction. The main questions this study seeks to answer are: * Does CO2 lift reduce the extent of bruising at 7 days post-surgery? * How does CO2 lift impact patient-reported pain and satisfaction? In this study, researchers will compare CO2 lift to a placebo (Vaseline) to see if the intervention has a positive effect. The study procedures include: * Baseline data collection of sociodemographic variables. Data collection of surgical variables, adverse events, … |
ALFREDO HOYOS; | 2025-04-30 |
| 83 | Using Fat Tissue GRafting to Treat Symptoms of VAginal Stenosis in Women With Gynaecological Cancer – IDEAL Stage 2a Surgical Study Related Papers Related Patents Related Grants Related Experts Highlight: The GRASS study looks at performing a technique called Fat Tissue Grafting to assess whether it can reduce the side effects of vaginal stenosis effects and improve the sexual function of participants who wish to preserve penetrative sexual function |
MARIELLE MS NOBBENHUIS; | 2025-09-01 |
| 84 | Comparison of Two Different Concentrations of Local Anesthetic in Patient Reported Pain in Oculoplastic Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this clinical trial is to compare pain scores in people undergoing upper eyelid surgery. The main questions it aims to answer are: – Is one concentration of local anesthetic (also called numbing or freezing injection) less painful when it is injected? – Does one concentration of local anesthetic provide better pain control during surgery? Participants will have two different concentrations of local anesthetic injected into the upper eyelid skin prior to surgery, and will be asked to rate the pain they have during the injection. At the end of surgery, … |
TIMOTHY EKHLASSI; | 2024-02-28 |
| 85 | Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve Block PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Background: Multimodal analgesia for control of postoperative pain in cardiac surgical patients helps in early recovery and ambulation. Pectoral nerve (PECS) block with ropivacaine is novel, less invasive regional analgesic technique with an effect comparable to paravertebral, and thoracic epidural analgesia. Aim: The aim of this study is to assess the effect of dexmedetomidine as an adjuvant to ropivacaine on the quality and efficiency of the ultra-sound guided pectoralis nerve block in patients undergoing open heart surgery through midline sternotomy for fast-track anesthesia and postoperative analgesia. |
MOHAMED AHMED HAMED; | 2024-08-20 |
| 86 | Palatal Donor Site Wound Healing Following Periodontal Plastic Surgery Using Amnion-Chorion Membrane: Site- and Patient-Centered Outcomes PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this clinical trial is to assess if donor site healing in the palatal area and patient pain perception are similar or different when using amnio-chorion membrane (ACM) on the donor site after surgery compared to a commonly used commercial hemostatic agent (ActCel Cellulose Gauze). |
BRIAN L MEALEY; | 2026-02-01 |
| 87 | Improving Palatal Donor Site Healing and Reducing Postoperative Morbidity With Concentrated Growth Factor and Collagen Fleece: Randomized Controlled Clinical Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative discomfort. The palatal donor site often requires several weeks to heal, and patients may experience pain, delayed epithelialization, and difficulty in daily oral functions. Biologically active materials such as CGF and collagen-based dressings may help accelerate tissue repair and improve patient comfort. A total of 38 systemically healthy adults requiring soft tissue graft harvesting were enrolled and assigned to three groups: CGF, CF, or control. In all groups, … |
CUNEYT ASIM ARAL; | 2026-01-28 |
| 88 | Patient Performed Tissue Expansion for Two-stage Alloplastic Breast Reconstruction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study is designed to evaluate the feasibility and safety of patient performed tissue expansions in two-stage alloplastic breast reconstruction with tissue expanders. The investigators hypothesize that a motivated patient who learns and demonstrates proper technique can safely perform tissue expansions at home, with no increase in complications or problems with reconstruction. 30 participants will be recruited for this study, 10 into a Home Expansion Group, and 20 into a Control Group. |
SAMUEL POORE; | 2024-06-01 |
| 89 | Histological Analysis of AlloMend® Acellular Dermal Matrix Used During The Initial Pre Pectoral Placement of Tissue Expanders for Breast Reconstruction and Evaluated at Time of Permanent Breast Implantation PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This is a prospective, histologic analysis of biopsied tissue obtained from participants who have undergone a pre-pectoral breast reconstruction or augmentation surgery with expander placement and AlloMend® Acellular Dermal Matrix. AlloMend® Acellular Dermal Matrix graft incorporation with surrounding native soft tissue using histological assays characterizing host cell infiltration, neovascularization, inflammation, and host replacement of ADM collagen will be studied. |
ALLOSOURCE | 2025-11-21 |
| 90 | Non-contrast Magnetic Resonance Angiography Efficacy and Safety Assessment for Perforators Mapping in Deep Inferior Epigastric Perforator Flap Breast Reconstruction PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of this study is to evaluate the efficacy and safety of contrast-free magnetic resonance angiography (MRA) for deep inferior epigastric perforator flap planning. The investigators propose to perform a non-contrast MRA to achieve the following extremely important objectives: to avoid radiation exposure, minimize the risk of potentially harmful effects of contrast agents, and reduce the cost of the study.The investigators assume that the use of non-contrast MRA following our protocol including certain patient’s positioning, a special pulse scanning sequence and perforators’ projection method is effective and allows mapping of perforators without injecting a potential harmful contrast agent. |
DMITRY V. MELNIKOV; | 2024-07-30 |
| 91 | Reduction of Breast Hypertrophy By Means of Coelioscopique Surgery Related Papers Related Patents Related Grants Related Experts Highlight: The objective of this interventional study is based on the hypothesis that coelioscopique surgery could be used to reduce breast hypertrophy. This study can be expected to scientifically validate the use of laparoscopic surgery to obtain a clinical result in the context of reduction of medium volume breast hypertrophy. |
GROUPE HOSPITALIER NORD ESSONNE | 2024-09-01 |
| 92 | A Phase III Clinical Study of The Efficacy and Safety of Lidocaine and Tetracaine Cream (CU-30101) in A Multicenter, Randomized, Double-Blind, Active-Controlled, Paired Design for Facial Laser Aesthetics in Chinese Adults PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Lattice laser is a new medical cosmetic technology, which is a kind of noninvasive and invasive technology. Compared with traditional laser therapy, lattice laser has a wider range of clinical use, and can be used to treat skin problems such as acne marks, fine wrinkles, skin aging, chloasma, coffee spots, large pores and dullness. Dot-array laser has been widely used in the treatment of skin diseases and skin cosmetics because of its advantages of small trauma, rapid recovery, safety and effectiveness, … |
CUTIA THERAPEUTICS（WUXI）CO | 2023-09-12 |
| 93 | Adipose Derived Regenerative Cells (ADRCs) in The Treatment of Diabetic Foot Ulcers: A Prospective, Double-blind, Multi-center, Randomized, Parallel-group Study PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: A Prospective, Double-blind, Multi-center, Randomized, Parallel-group safety and efficacy study of adipose-derived regenerative cells (ADRCs) in the treatment of patients with diabetic foot ulcers (DFU). |
PARACRINE | 2025-07-01 |
| 94 | Comparative Study of The Effect of Oxidant Gel and Anti-oxidant Gel on Wound Healing After Gingival Depigmentation. (A Randomized Controlled Clinical Trial) PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: To evaluate effect of Oxidant (Oxygen Releasing Oral Gel) with Coe-Pak versus Anti-oxidant (Nano-emulsion complex propolis and vitamin C gel) with Coe-Pak on wound healing, pain, patient satisfaction after gingival depigmentation |
HADEER METWALLY SHAFIK METWALLY; | 2024-05-01 |
| 95 | Evaluation of Different Periodontal Plastic Surgery Techniques for Gummy Smile Treatment PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Investigating different periodontal surgery techniques to treat gummy smile. |
EGAS MONIZ COOPERATIVA DE ENSINO SUPERIOR CRL | 2023-12-15 |
| 96 | Development of Three-dimensional Deep Learning for Automatic Design of Skull Implants Related Papers Related Patents Related Grants Related Experts Highlight: This project aims to develop an effective deep learning system to generate numerical implant geometry based on 3D defective skull models from CT scans. This technique is beneficial for the design of implants to repair skull defects above the Frankfort horizontal plane. |
YAU-ZEN CHANG; | 2023-07-15 |
| 97 | The Effect of Neurotization on Quality of Life and Sensory Restoration After Autologous Breast Reconstruction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This is a single-site, randomized, double-blinded trial to assess whether neurotization following autologous breast reconstruction in patients with breast cancer increases quality of life and sensation in the breast compared to breast reconstruction without neurotization. 50 participants will be enrolled and can expect to be on study for up to 18 months after reconstruction surgery. |
BRETT F MICHELOTTI; | 2024-01-01 |
| 98 | The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Several studies have attempted to calculate the ideal epinephrine concentration for vasoconstriction, however there has been little consensus. These experiments were carried out on animals, and the degree of vasoconstriction was measured using a variety of methods. Animal studies aren’t always reliable since animal capillary density differs from human capillary density. Furthermore, because the density of capillaries in the head and neck is 30 to 40% higher than in other parts of the body, previous studies may not adequately reflect the ideal epinephrine concentration for this highly vascular location. As a result of this study, … |
ERUM NAZ; | 2023-07-30 |
| 99 | The Effectiveness of Using Vibration Device to Ease Pain During Injections Into The Upper Extremity: A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Background: Vibratory stimulation is one of several non-pharmacological techniques used to reduce pain. Local vibration therapy generates vibrations that can penetrate up to 6 centimeters into the tissue and is utilized to manage muscle tone, alleviate localized pain, and induce an increase in blood and lymphatic circulation. This therapy is most commonly used to treat chronic pathologies of the muscles, tendons, … |
HATAN MORTADA; | 2025-03-06 |
| 100 | Examining The Effect of Additional Injection of Freshly Collected Autologous Adipose Tissue to Bascom’s Cleft Lift Surgery in The Treatment of Pilonidal Disease- A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: In brief, the right management of complex or recurrent pilonidal disease (PD) is still controversial. In our institution we treat these conditions with Bascom’s cleft lift surgery. Though this approach for most parts is beneficial, … |
SUSANNE HAAS; | 2026-03-31 |
| 101 | Retrospective Data Collection on The Use of Motiva Flora TE in Breast Reconstruction PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The Motiva Flora® TE are intended for temporary subcutaneous or submuscular implantation to develop surgical flaps and additional tissue coverage and are not intended for use beyond six (6) months. All Motiva Flora® TE’s require periodic, incremental inflation with sterile saline for injection until the desired tissue amount is developed. After the desired volume, the expander is surgically removed and replaced with a long-term breast implant in the same space as the tissue expander. The study collects retrospective data on the use of the Motiva Flora TE, … |
ESTABLISHMENT LABS | 2023-04-01 |
| 102 | The Role of Lipofilling After Oncoplastic Breast Surgeries : Evaluation of Outcomes and Patient Satisfaction PF:2 Related Papers Related Patents Related Grants Related Experts Abstract: Lipofilling is the process of relocating autologous fat to change the shape, volume, consistency and profile of tissues. For over a century, surgeons have used autologous fat to … |
MINA RASHAD HELMY BESADA; | 2024-09-01 |
| 103 | Post-surgical Scars After The Use of CACIPLIQ20: A Randomized, Double-blind, Placebo -Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Following surgical procedures or injury, cutaneous scars can develop due to production of collagen-rich connective tissue. These scars may be accompanied by redness, itching, pain, and restricted mobility of the skin. Typically, after a few weeks, the scar matures, becoming lighter and narrower, although full maturation of a scar may take up to 2 years. In some cases, however, cutaneous scars can be unsightly or can even become hyper- … |
GILBERT ZAKINE; | 2023-12-01 |
| 104 | Validity and Reliability of Arabic Version of Breast Questionnaire for Post Mastectomy Patients PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: To test validity and reliability of the translated Arabic version of breast questionnaire . |
CAIRO UNIVERSITY | 2023-02-01 |
| 105 | Study of The Long-Term Effectiveness of The Motiva Implants® Round and Round Ergonomix in Primary and Revision Breast Augmentation PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Post-marketing surveillance study to demonstrate the silent rupture rate and satisfaction of patients who underwent a primary and revision breast augmentation surgery with Motiva Implants®, 3 to 10 years before enrollment. |
POURIA MORADI; | 2022-12-31 |
| 106 | Metabolomic Evaluation of Psycho-surgical Synergy on Body Image Restoration After Breast Cancer PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of the present study is to verify the effects of a psychological-clinical intervention supported by the technique of expressive writing, on the post-operative course in terms of mental and physical health in patients undergoing surgical mastectomy treatment with post-oncological breast reconstruction. In particular, it is hypothesised that patients undergoing psychological, emotional and social well-being in the phase following surgical treatment, together with an improvement in the inflammatory profile and a possible change in the tryptophan/kynurenine ratio and cortisol. For this purpose, … |
CARLO LAI; | 2024-01-30 |
| 107 | A Single Center, Randomized Study to Evaluate Skin Characteristics After Facial Autologous Fat Grafting to Both Sides of The Face Using Saline Washed or Unwashed Fat Graft PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this study is to specifically examine changes in facial skin appearance after facial fat grafting with autologous fat tissue that has either been washed with sterile saline before injecting, or left unwashed. This will be testing two variations of a standard of care surgical procedure, in two cohorts of subjects. One group will receive washed fat, and one group will receive unwashed fat, to both sides of the face. There are no experimental devices, drugs, … |
J. PETER RUBIN; | 2025-11-05 |
| 108 | Post-market Monitoring and Control of Safety and Efficacy of Silimed® Breast Implants With Smooth Surface (STEPS S) PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The study investigates the safety and performance of Silimed® brand smooth surface breast implants in women born with indication for primary and secondary (revision) augmentation to be followed up for 10 years. The safety of the smooth-surfaced Silimed® implant will be evaluated by estimating known and unexpected short-term and long-term risk/adverse event rates through patient reports of adverse events after implantation. The performance of using Silimed® brand smooth surface breast implants will be evaluated by evaluating satisfaction and quality of life after implantation. |
ANDRÉ LUIZ P DE FREITAS; | 2026-03-16 |
| 109 | Optimization of Surgical Treatment of Patients With Postoperative Median and Median-lateral Ventral Hernias PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by developing new surgical techniques. The main questions it aims to answer are: 1. To study the topographic and variant anatomy of vessels and nerves in the retromuscular, preperitoneal, postperitoneal and pre-abdominal cell spaces of the anterior abdominal wall. To determine the most probable sources of blood flow and lymph from the anatomical formations forming the bed of the endoprosthesis. 2. To develop technical, … |
SAMARA STATE MEDICAL UNIVERSITY | 2025-05-23 |
| 110 | Porcine Acellular Dermal Matrix for The Treatment of Localized Gingival Recessions: A Multicenter Randomized Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Aim: The aim of this randomized clinical trial is to evaluate the use of the porcine acellular dermal matrix (PADM) for the treatment of RT1 localized gingival recessions. Material and methods: Forthy patients (n=20) with RT1 localized gingival recessions with height ranging from 3 to 5 mm with and at least, 2mm of keratinized tissue width will be selected to participate in the study. Patients will be allocated randomly in two treatment groups: Coronally advanced flap (CAF) or coronally advanced flap associated with the porcine acellular dermal matrix (CAF+ PADM). The clinical parameters evaluated at the baseline, … |
ENILSON ANTONIO SALLUM; | 2025-04-02 |
| 111 | DermaClose Continuous External Tissue Expander for The Management of Four-Compartment Fasciotomy and Full-Thickness Wounds Related Papers Related Patents Related Grants Related Experts Highlight: To evaluate the clinical performance of DermaClose and DermaClose XL Continuous External Tissue Expander (CETE) devices to reduce wound size and/or assist with closure in acute full thickness wounds of the skin and assess the need for skin grafting for patients undergoing a four-compartment leg fasciotomy. |
BAXTER HEALTHCARE | 2025-03-21 |
| 112 | A Randomized Control Trial Evaluating The Use of Topical Tranexamic Acid in Bilateral Breast Reduction Surgery to Prevent Bleeding Complications PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Hematoma is a common complication of bilateral breast reduction (BBR) surgery. This can lead to pain and discomfort experienced by the patient, in addition to greater use of valuable healthcare resources. Previous studies have shown correlation between the use of tranexamic acid (TXA), an anti-fibrinolytic, and reduced post-surgical bleeding complication events. In this randomized control trial (RCT) evaluation TXA use in BBR, for which one breast will be randomized to have TXA applied topically, … |
CHRISTOPHER CORONEOS; | 2024-08-01 |
| 113 | 3D Telemedicine: Randomised Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This randomised controlled trial will provide definitive answers to whether a 3D telemedicine system makes a remote consultation more similar to meeting a doctor face-to-face, than a 2D Telemedicine consultation. This will be measured using a Presence scale – which is a measure of the realism or immersion of the system – … |
NHS GREATER GLASGOW AND CLYDE | 2023-03-31 |
| 114 | Intra-lesional ACE Inhibitor for Treatment of Keloid Scars PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Keloid scarring is a difficult and debilitating condition where one develops excessive scarring after incision or laceration to the skin. Currently, there is no reliable treatment of these scars. One of the more effective treatments available is serial intralesional injection of a steroid after 90% excision of the keloid scar. Angiotensin II is an active peptide in the body that results in vasoconstriction of the blood vessels when activated. Medications used today like angiotensin II receptor blocks and angiotensin converting enzyme inhibitors work to prevent the activation of angiotensin II and are mainly used to help control blood pressure. Previous studies in rat models have shown that angiotensin II receptor blockers can effectively reduce scar hypertrophy (a hallmark of keloid scarring). In this study, the investigators will conduct a randomized control trial, with one arm receiving the standard therapy of 90% excision of the keloid scar with serial intra-lesional injections of triamcinolone injection and the second arm receiving a combination of triamcinolone + ACE-inhibitor. The outcome will be measured using the Patient and Observer Scar Assessment Scale (POSAS), a validated assessment tool. |
BRADLEY GREENE; | 2023-10-01 |
| 115 | Association of Silicone Breast Implant Reconstruction and -Enlargement With Overall Wellbeing, Lymphoma and Auto-immune Disease – Breast Implant Illness PF:8 Related Papers Related Patents Related Grants Related Experts Highlight: Background: Implant-based breast reconstructions contribute considerably to the quality of life of breast cancer patients. A knowledge gap exists concerning the potential role of breast implants in the development of so called ‘breast implant illness’ and autoimmune diseases in breast cancer survivors with a silicone breast implant-based reconstruction. Breast implant illness is a constellation of non-specific symptoms reported by a small group of women with silicone breast implants. Methods/Design: The Areola study is a multi-centre historic cohort study with prospective follow-up aiming to assess the risk of ‘breast implant illness’ and autoimmune diseases in female breast cancer survivors with and without silicone breast implants. The cohort consists of breast cancer survivors who received surgical treatment with silicone implant-based reconstruction in six major hospitals across the Netherlands in the period between 2000 and 2015. As comparison group, a frequency-matched sample of breast cancer survivors without breast implants will be selected. An additional group of women who received breast augmentation surgery in the same years will be selected to compare their characteristics and health outcomes with those of breast cancer patients with implants. All women still alive will be invited to complete a web-based questionnaire covering various health related topics. The entire cohort including deceased women will be linked to the population based computerized databases of Statistics Netherlands. These databases include a registry of diagnostic codes, a pharmacotherapeutic prescriptions registry and a cause-of-death registry in which diagnoses of autoimmune diseases will be identified. Outcomes of interest are the prevalence and incidence of BII and the prevalence and incidence of autoimmune diseases. In addition, risk factors for the development of BII and autoimmune disorders will be assessed among women with implants. Discussion: The Areola study will contribute to the availability of reliable information on the risks of breast implant illness and autoimmune diseases in Dutch breast cancer survivors with silicone breast implants. This will inform breast cancer survivors and aid future breast cancer patients and their treating physicians to make informed decisions about reconstructive strategies after mastectomy. Keywords: Silicone breast implants, Breast reconstruction, Breast cancer, Breast Implant Illness, Autoimmune disease |
SANNE SCHAGEN; | 2025-06-01 |
| 116 | The Fat Analysis Trial (FAT): The Impact of Lip-aspirate Processing on Fat Resorption in Autologous Fat Grafting to The Breast: A Randomized Controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Fat grafting has been gaining popularity over the past decade. It is now commonly used for breast augmentation and reconstruction, however a major challenge remains the high rate and unpredictable rate of fat resorption post-operatively, leading to volume loss and patient dissatisfaction. Currently there is no consensus on the ideal technique to process donor fat to minimize the rate of resorption. Our study aims to compare two common processing methods to determine if one is superior for fat volume retention. |
TANYA DELYZER; | 2025-07-01 |
| 117 | Efficacy of Intraoperative Brimonidine for Hemostasis During Eyelid Surgery PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is to observe and report the effects of topical ophthalmic brimonidine in oculofacial plastic surgery. |
CHRISTOPHER COMPTON; | 2022-12-30 |
| 118 | Safety and Efficacy of Allograft Adipose Matrix Injectable for Glottal Insufficiency PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Renuva is allograft adipose matrix commonly used as a filler in cosmetic procedures. The investigators are studying this material as an injectable in the vocal fold to treat glottic insufficiency. Currently, many products can be used as an injectable in the vocal fold to correct glottic insufficiency such as carbomethycellulose, hyaluronic acid, collagen derivatives and calcium hydroxyapatite amongst others. An ideal injectable would not impair the fibroelastic property of the vocal fold tissues and would integrate within the tissue of the vocal fold. Since Renuva has the property of stimulating adipogenesis by using growth factor and collagen, … |
KARLA O’DELL; | 2025-07-01 |
| 119 | Lymphaticovenous Anastomosis As A Surgical Treatment for Breast Cancer-Related Lymphedema PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The primary aim of this study is to investigate and test whether the use of combined indocyanine green (ICG) lymphography and ultra high frequency ultrasonography can correctly identify lymphatic vessels and venoles in close proximity to each other, for identification prior to lymphovenous anastomosis (LVA) surgery. |
CAROLINE LILJA; | 2024-01-31 |
| 120 | Mapping Arterial Perforators of The Nipple Areolar Complex and The Horizontal Septum During Mammoplasty PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Breast cancer surgery can often be carried out as part of a breast reduction procedure known as ‘therapeutic mammoplasty’. Where a woman has a breast with adequate volume, even larger cancers can be removed in an aesthetically acceptable way with re-shaping of the breast (often reduction and lift) incorporated into the cancer removal. An expectation and desire for most women is that the nipple and areola (known as the ‘nipple-areolar complex’ or NAC) is not only preserved, but re-positioned (usually lifted) to re-balance the overall aesthetic result. In moving the NAC, … |
PETER A BARRY; | 2024-01-29 |
| 121 | Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this randomized control trial is to in [describe participant population/health conditions]. The main question it aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 20cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 20cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline. |
CHRISTOPHER HUGHES; | 2026-04-01 |
| 122 | Preop Education and Opioid Use After Distal Radius Open Reduction and Internal Fixation (ORIF): A Randomized Controlled Trial at A County Hospital PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study will compare opioid consumption in patients undergoing outpatient surgical fixation of distal radius fractures with and without standardized preoperative education at Grady Memorial Hospital. |
PAUL GHAREEB; | 2023-04-01 |
| 123 | Safety and Feasibility of Robotic Single-port (SP) Nipple Sparing Mastectomy: A Single Institution, Single Arm Pilot Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This is a single arm, single-center, prospective clinical trial designed to track the peri, post-operative and oncologic outcomes when utilizing the da-Vinci single port (SP) robotic platform to perform robotic nipple sparing mastectomy (rNSM) and immediate breast reconstruction with tissue expanders/implants and acellular dermal matrix (ADM – Alloderm), for patients with breast cancer as well as those with a high risk for breast cancer. Safety and feasibility measures will be measured as primary outcome measures. Oncological and patient satisfaction outcome measures will be measured. Our hypothesis is that SPr-NSM is equal to open NSM in terms of safety, … |
DEBORAH FARR; | 2026-03-20 |
| 124 | Studying How Outpatient Water AffEcts Risks With Drains (SHOWER Study) PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This is a prospective randomized, controlled, unblinded, interventional feasibility study to evaluate if showering with post operative drains in place leads to an increase in complications. The patients included in the study will be those undergoing breast reductions and panniculectomies at Geisinger Medical Center. The patients will be randomized post operatively into one of two groups: 1) patients instructed to shower with drains in place, and 2) patients instructed not to shower while they have drains in place. |
SEAN DEVITT; | 2026-02-20 |
| 125 | IMPACT OF TRANEXAMIC ACID IN TUMESCENT SOLUTION ON POSTOPERATIVE OUTCOMES AFTER LIPOSUCTION: A DOUBLE-BLIND, CONTRALATERAL ARM RANDOMIZED CLINICAL TRIAL PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this trial is to evaluate the effect of adding Tranexamic Acid (TXA) to the tumescent solution used in arm liposuction on postoperative outcomes. Study population includes healthy volunteer adults undergoing Liposculpture procedures. The main question it aims to answer is: 1. Does Tranexamic acid exert benefit on postoperative outcomes after liposuction? Researchers will compare TXA versus traditional tumescent solution to see if there are benefits on adding it to the tumescent solution. Participants will undergo High Definition Liposculpture involving arms, … |
ALFREDO HOYOS; | 2025-04-30 |
| 126 | New Autologous Fat Graft for The Treatment of Urethral Stricture PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: In 2001 Zuk showed that lipoaspirate contains multipotent adipose stem cells (ADSCs) like in the bone marrow, thereby expanding opportunities in multiple fields. ADSCs have emerged as a key element of regenerative medicine surgery due to their ability to differentiate into a variety of different cell lineages. Moreover, their capacity of paracrine secretion of a broad selection of cytokines, chemokines, and growth factors makes them highly clinically attractive. More specific, of particular interest are the anti-apoptotic, anti-inflammatory, proangiogenic, immunomodulatory, and anti-scarring effects that have been demonstrated for ADSCs, which effects on wound healing, soft-tissue restoration, … |
ANTONIO LUIGI PASTORE; | 2023-01-01 |
| 127 | Auricular Reconstruction in Microtia By Medpor Implant Following Tissue Expansion Related Papers Related Patents Related Grants Related Experts Highlight: The study involves patients with microtia of certain criteria will undergo tissue expansion by silicone bags in the postauricular region then Medpor implants will be applied undercover of the expanded skin for reconstruction of the auricule instead of the costal cartilage graft |
MINA YOUSSEF ASHAM GENDY; | 2024-01-01 |
| 128 | Use of TRanEXamic Acid in Reduction Mammoplasty (TREX-ARM): A Double-blinded Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM. Hematoma-related complications include unplanned surgery, need for blood transfusion, wound healing issues, and unfavorable surgical outcomes. Tranexamic acid has emerged in the literature as a promising agent that reduces perioperative blood loss and need for transfusion. However, despite its consistently reported efficacy, low cost, and favorable safety profile, tranexamic acid remains underutilized in plastic surgery. The investigators propose a prospective, … |
JOSEPH A RICCI; | 2022-07-13 |
| 129 | Enhanced Recovery After Bilateral Reduction Mammaplasty PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This single-center, clinical trial is being conducted to determine whether non-narcotic pain regiments are as effective as narcotic-based regiments in reducing post-operative pain in patients undergoing breast reduction in the outpatient setting. |
JEFFREY M. KENKEL; | 2024-06-01 |
| 130 | The Aesthetic and Functional Impact of Monsplasty in Women Undergoing Abdominoplasty PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Evaluate The aesthetic and function satisfaction outcomes of different monsplasty surgery with or after abdominoplasty |
MOSTAFA MOHAMED HASSAN; | 2023-05-01 |
| 131 | Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This is a prospective, within-subject randomized, single blinded study designed to follow up to forty-two (42) qualified and consenting adult females, 18-65 years of age scheduled for elective breast reduction surgery using a standard inverted Wise (inverted T) incision pattern |
JEFFREY M. KENKEL; | 2025-07-02 |
| 132 | Smoking Increases The Risk of Postoperative Wound Complications: A Propensity Score-matched Cohort Study PF:10 Related Papers Related Patents Related Grants Related Experts Highlight: Cigarette smoking is associated with surgical complications, including wound healing and surgical site infection. However, the association between smoking status and postoperative wound complications is not completely understood. Our objective is to investigate the effect of smoking on postoperative wound complications for major surgeries. |
CHAO-SHUN LIN; | 2021-12-02 |
| 133 | Philtrum Reconstruction Using Autogenous Fat Injection Versus A Surgical Repair With Orbicularis Reconstruction, in Secondary Unilateral Cleft Lip Revision (A Randomized Clinical Trial) PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair. – The first group will receive upper lip fat injections into the philtral column (and other areas of volume insufficiency if needed) after manual fat liposuction from the abdomen. – The second group will receive surgical lip revision with reconstruction of the orbicularis oris muscle using inverted horizontal mattress sutures for enhancement of the philtral ridge. |
SHEREEN ISHAK FARIS; | 2022-12-01 |
| 134 | Computer Modelling Using 2D and 3D Photographs of Patients Faces to Improve Surgical Reconstructive Planning in A Clinical Case Series of Patients With Facial Defects and Improve Patient Satisfaction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The aim of this study is to improve patient satisfaction and outcomes in facial reconstructive surgery by using 3D clinical photography and computer modelling to help illustrate and plan the patients’ reconstructive journey. It will be conducted at the Royal Free Hospital department of Plastic and Reconstructive Surgery, where patients with facial deformities or suspected diagnoses of skin cancer will be referred from their GP or dermatology services. As is routine standard of care, … |
PRATEUSH SINGH; | 2022-10-01 |
| 135 | A Comparison of 3D and 2D Telemedicine: Communication During Covid 19 PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: It is critical to establish an effective form of telemedicine during the Covid 19 pandemic, that will allow safe social distancing of clinicians and patients. The investigators serve as the regional plastic, burns and reconstructive centre for the West of Scotland, population 3 million. All face to face clinics have been cancelled and converted to telephone/telemedicine only consultations. The investigators will establish both 2D and 3D telemedicine as normal patient follow up practice during this period. The aim is to implement a 3D telemedicine system to facilitate patient follow up and remote physiotherapy, … |
STEVEN LO; | 2021-12-31 |
| 136 | Artificial Intelligence Augmented Training in Skin Cancer Diagnostics for Skin Cancer Specialists PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Background: The worldwide incidence of skin cancer has been rising for 50 years, in particular the incidence of malignant melanoma has increased approx. 2-7% annually and is the most common cancer amongst Danes aged 15-34. Currently there is a significant amount of misdiagnosis of skin cancer and mole cancer, and most excised skin lesions are benign. Previous studies have shown that there is no significant increase in doctors diagnostic accuracy during the first 6 years of clinical work. The resources spend on healthy people could be put to better use, … |
GUSTAV GEDE NERVIL; | 2025-09-30 |
| 137 | A Clinical Effectiveness Study of Total Laparoscopic Subcutaneous Gland Resection Combined With Nipple-Areola Complex Lift in The Management of Moderate to Severe Gynecomastia in Males PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This study aims to evaluate and compare the treatment outcomes of total laparoscopic subcutaneous gland resection combined with nipple-areola complex (NAC) lift surgery against those of isolated laparoscopic surgery in the management of moderate to severe gynecomastia (GYN) in males. |
FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY | 2026-01-02 |
| 138 | The Relationship Between Postoperative Complications and Wetting Solution-ideal Body Weight Ratio in Liposuction Procedures PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Although the use of wetting solutions during high-volume liposuction is a standard approach, it is unclear how to optimize wetting solutions and components and their effect on postoperative complications.. Since the super-wet technique (aspiration of 1 cc per 1 cc of infiltrate) was introduced in 1986, it has become one of the most frequently applied techniques worldwide . Adrenaline and lidocaine are often added to WS due to their hemostatic and analgesic effects One of the major advantages of super-wet technique is that blood loss is quite low. However, … |
SERAP AKTAS YILDIRIM; | 2023-10-30 |
| 139 | 3D Telemedicine During COVID-19: Non-clinical Validation PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Telemedicine will be used as standard practice during the Covid Pandemic, in order to reduce clinician exposure to patients and potential high viral load, and reduce patient footfall in a hospital caring for Covid patients. The 3D telemedicine uses multiple cameras in the clinic room which can reconstruct an image in 3 dimensions. This may give more information about a patient’s condition, particularly in more visual specialties such as Plastic Surgery. The systems have hospital approval to be used for telemedicine, all equipment is CE marked. There are no data regarding the use of 3D telemedicine, … |
NHS GREATER GLASGOW AND CLYDE | 2021-12-31 |
| 140 | Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results. CSEGA has several known advantages including appropriate postoperative analgesia, shows some benefit in the intraoperative blood loss control causing a decreased need for blood transfusion, rapid regain of the gastrointestinal actions and decreases the incidence of postoperative respiratory complications. Unfortunately, the drawbacks of using neuro-axial anesthesia in combination to general anesthesia will be not thoroughly introduced in many researches, thus, remain unclear. |
AMR SAMIR WAHDAN; | 2023-09-01 |
| 141 | Indications for Breast Reduction in The Public Health Care System PF:6 Related Papers Related Patents Related Grants Related Experts Highlight: The overall purpose of the project is to create a scientific basis for which patients should be offered breast reduction in the public sector. More specifically , the project aims to: * To examine the evidence for current national guidelines for breast reduction. The hypothesis is that BMI, breast volume, resection weight, and mental and physical symptoms affect the outcome of breast reconstruction, both in terms of complication risks, patient satisfaction and quality of life . * To investigate which patients benefit the most from a breast reduction, … |
EMMA HANSSON; | 2025-07-03 |
| 142 | The Use of N-acetylcysteine Supplementation in Addition to Night Splinting for Treatment of Mild to Moderate Carpal Tunnel Syndrome: A Randomized, Double-blind, Placebo-controlled Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Carpal tunnel syndrome (CTS) is the most common nerve compression syndrome worldwide, causing significant chronic pain, functional impairment, and lowered quality of life for individuals of various backgrounds. CTS is caused by chronic compression of the median nerve in the carpal tunnel of the wrist, causing numbness and pain in the palm, thumb, index, and middle fingers and eventual weakness of the hand. Many different treatments for CTS have been proposed and studied, including but not limited to non-operative treatments such as wrist splinting, steroid injections, and lifestyle modifications as well as operative treatments, … |
DAVID TANG; | 2023-05-01 |
| 143 | Study Protocol for Comparison of Lower Eyelid Retraction Repair With Hard Palate, Autologous Ear Cartilage, and Porcine Acellular Dermal Matrix Spacer Grafts PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2) |
ANNE BARMETTLER; | 2024-12-22 |
| 144 | Reliability of Chest Wall Perforator Flaps for Breast Reshaping Following Massive Weight Loss PF:2 Related Papers Related Patents Related Grants Related Experts Abstract: Conditions for inclusion in the study: – Ptotic and deflated breasts following massive weight loss (MWL) with Pittsburgh Rating Scale (PRS) score of 2-3 as described by Songet al. … |
AIN SHAMS UNIVERSITY | 2024-01-01 |
| 145 | The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Tranexamic acid (TXA) is a synthetic inhibitor of plasminogen lysine receptor that has used to reduce intra-operative bleeding in a number of clinical scenarios. Anecdotally, TXA has used by plastic surgeons to reduce post-operative bruising. To date, there is limited data to valid the benefits and to evaluate the side effects of TXA. The objective of this study is to evaluate the effect of local TXA on edema and ecchymosis in eyelid surgery. |
DIANNE SCHLACHTER; | 2022-07-01 |
| 146 | A Translational Study of Breast-implant AssocIated AnaplastIc Large Cell Lymphoma and Capsular Contracture PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: BASILICA is a UK NIHR Biomedical Research Centre funded study recruiting patients at The Royal Marsden NHS Foundation Trust. The study aims to obtain blood and tissue samples from patients with breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), capsular contracture and implant-naïve patients undergoing primary implant insertion surgery for translational scientific analysis. |
AADIL KHAN; | 2024-07-27 |
| 147 | 3D Telemedicine During COVID-19: Cohort Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: It is critical to establish an effective form of telemedicine during the Covid 19 pandemic, that will allow safe social distancing of clinicians and patients. Canniesburn Regional Plastic Surgery and Burns Unit serves as the regional plastic, burns and reconstructive centre for West of Scotland, population 3 million. All face to face clinics have been cancelled and converted to telephone/telemedicine only consultations. The research will establish both 2D and 3D telemedicine as normal patient follow up practice during this period.The project therefore aims to implement a 3D telemedicine system to facilitate patient follow up and remote physiotherapy, … |
NHS GREATER GLASGOW AND CLYDE | 2022-03-31 |
| 148 | ANALYSIS OF THE IMPACT ON THE MICRO SURGICAL TECHNIQUE IN RESIDENTS AFTER A THEORETICAL-PRACTICAL COURSE OF MICROSURGERY: A SINGLE GROUP STUDY PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: A single group study will be carried out in the Microsurgery Laboratory, Neurosurgery Department, Hospital de Clínicas, and the Center for Microsurgical Skills of the Argentine Association of Neurosurgery. The objective of the study is to evaluate the effect of theoretical-practical course learning in neurosurgery and plastic surgery residents. |
MARCOS EZEQUIEL YASUDA; | 2022-12-15 |
| 149 | Prospective Comparison of The Revolve™ and AuraGen 1-2-3™ With AuraClens™ Systems in Processing of Lipoaspirate for Autologous Fat Grafting to The Breast PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is to compare fat graft retention over time from lipoaspirate processed using two FDA-cleared devices: the Revolve System (K120902) and the AuraGen 1-2-3 with AuraClens Lipoaspirate Wash System (BK190433). |
DANIEL A DEL VECCHIO; | 2022-12-31 |
| 150 | A Multi-institutional Randomized Controlled Trial to Determine The Optimal Antibiotic Prophylaxis for Tissue Expander-based Breast Reconstruction PF:5 Related Papers Related Patents Related Grants Related Experts Highlight: This study is a prospective, multi-institutional, noninferiority, randomized control trial that will compare the efficacy of two antibiotic treatments in preventing SSI in patients receiving immediate breast reconstruction with tissue expanders (TE-BR). The patients will be randomly assigned to one of the two treatment groups. One group will receive a single dose of antibiotics just before surgery and if necessary, more doses during the surgery. The other group will receive the same treatment as the first group, … |
CHRISTINE ROHDE; | 2023-12-01 |
| 151 | Aesthetic Analysis of Gluteal Deformity After Weight Loss and Assessment The Role of Autologous Tissue Augmentation for Gluteal Contouring PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: this study aim to evaluate the role of autologous augmentation for buttock contouring and analyze different aethetic gluteal deformity |
MOHAMMED KAMAL KAMEL; | 2024-01-01 |
| 152 | Elaborated Analysis of Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty on Corneal Nerves, Meibomian Glands, Dry Eye Parameters, and Eyebrow Position PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study aims to evaluate the short and long-term effects of skin-only and skin+muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow position. |
VOLKAN DERICIOĞLU; | 2022-08-01 |
| 153 | Is Autologous Platelet Rich Plasma Able to Restore Ovarian Function? A Prospective Randomized Control Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: A-PRP (Autologous Platelet Rich Plasma) is becoming widely used in a variety of medical procedures seeking tissue remodeling and/or healing as an intervention. To date, applications in orthopedics, wound healing, dermatology and plastic surgery have gained general acceptance, primarily as the role of platelets and their activation in tissue repair and recovery has become better understood at a cellular and molecular level. This study will involve adult women with a diagnosis of Premature ovarian insufficiency (POI) willing to perform an IVF/ICSI treatment. |
LAURA MELADO; | 2025-02-19 |
| 154 | Comparison of Safety and Patients-Reported Outcomes Between Single-Port Endoscopic and Conventional Nipple-Sparing Mastectomy With Immediate Implant Reconstruction: A Retrospective Cohort Study PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Why is this study being done? Breast cancer is very common among women. Today, patients not only seek effective treatment but also care about their quality of life after surgery, including how they feel and how satisfied they are with the results. Doctors have developed different surgical methods. One newer method uses a tiny camera (called an endoscope) to perform the surgery through small openings, while the traditional method uses a larger incision. The newer method may lead to better cosmetic results and faster recovery, … |
ZHANG JULIANG-1; | 2026-02-13 |
| 155 | The Degree of Health Technologies Readiness Amongst Patients With Suspected Breast Cancer Using The READHY-tool PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: This study aims to investigate the degree of Health Technologies Readiness amongst patients with suspected breast cancer using the READHY-tool. |
MARTIN SOLLIE; | 2021-08-31 |
| 156 | Efficacy of Platelet Rich Plasma Injection Plus Fat Grafting As Compared to Fat Grafting Alone on Burn Scar By Using Vancouver Scar Scale Related Papers Related Patents Related Grants Related Experts Highlight: Background: – Burn injuries always leave behind some permanent marks on the body of a victim. For the treatment of these scars, digital photography along with scar scales instrument are an important instrument for the patient’s evaluation and finally for the follow-up of scars. Clinical evaluation of the patient after the use of Platelet concentration that it is a beneficial treatment which affects both on hard and soft tissues healing because of having growth factors deposited in PRP. Therefore, it can be used as an alternative to surgery which promotes safe and natural healing in such patients. Objectives: – … |
NASREEN BANO; | 2021-09-28 |
| 157 | Evaluation of Stem and Immune Cells in The Early Stage Breast Cancer Without Genetic Risk PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Monocentric, observational and prospective study in adult women having an early-stage breast cancer without genetic risk. The main objective is to characterize quantitatively and qualitatively, after solitary confinement, the resident breast stem cells and the immune system cells infiltrated in the mammary gland in women: – With a moderate risk of breast cancer progression (women with an early Luminal A tumor) = Group A. – With a high risk of breast cancer progression (women with an early Luminal B or basal tumor) = Group B. |
DELAY EMMANUEL; | 2024-11-15 |
| 158 | COMBINATION OF LYMPHATICO-VENULAR ANASTOMOSIS AND LIPOSUCTION TO TREAT CANCER-RELATED LYMPHEDEMA: RATIONALE FOR A REGIONAL APPROACH PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: – cooperation of an International team with many years of experience in surgical management of lymphedema – description of an effective surgical strategy to treat cancer-related lymphedema, a high incidence pathology – the combination of LVA and liposuction guarantees long lasting results |
GUIDO GABRIELE; | 2025-05-01 |
| 159 | Prophylactic Treatment of Breast Implants With A Solution of Gentamicin, Vancomycin and Cefazolin Antibiotics for Women Undergoing Breast Reconstructive Surgery: A Randomized Controlled Trial (The BREAST-AB Trial) PF:5 Related Papers Related Patents Related Grants Related Experts Highlight: The BREAST-AB Trial is a multi-center, randomized, double blind, placebo-controlled trial investigating the efficacy of local application of gentamicin, vancomycin and cefazolin in decreasing all-cause implant explantation after breast reconstruction. |
MIKKEL HERLY; | 2026-02-12 |
| 160 | Multicentre, Controlled, Randomized, Investigator-blinded Clinical Trial on Efficacy and Safety of Surgical Therapy of Lipedema Compared to Complex Physical Decongestive Therapy Alone (LIPLEG) PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is to determine whether surgical treatment of lipedema (stage I, II or III) using liposuction significantly improves leg pain compared to the use of complex decongestive therapy (CDT). |
HAUTKLINIK DARMSTADT | 2025-03-19 |
| 161 | Molecular Mechanisms Associated With Breast Implant Complications PF:5 Related Papers Related Patents Related Grants Related Experts Highlight: Bacterial biofilms cause implant failures, chronic inflammation, and immune polarization. The study investigates the possible role of bacterial biofilm as a factor in the etiology of Breast Implant Illness. Three patient cohorts will be studied (A) Subjects with breast implant with BII manifestations (B) Subjects with breast implants without BII manifestations (C) Subjects without breast implants who underwent breast surgery procedure. Blood, surgically discarded tissue, implants, and associated capsules will be collected through this protocol. |
MITHUN SINHA; | 2025-04-10 |
| 162 | Artificial Intelligence Screening for Body Dysmorphic Disorder in Aesthetic Surgery: Improving Patient Safety and Outcomes PF:6 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this observational study is to evaluate the effectiveness of an AI-powered screening tool for Body Dysmorphic Disorder (BDD) among patients seeking aesthetic surgery. The study aims to determine if the AI system can effectively identify patients at risk for BDD and assess the impact of early psychological intervention on surgical decision-making and outcomes. Participants will complete a comprehensive AI-based risk assessment, which includes the Body Dysmorphic Disorder Questionnaire (BDDQ). The study will track the correlation between BDD, age, stress levels, and gender to better understand the prevalence and implications of BDD in cosmetic surgery. |
WILLIAMS E BUKRET; | 2024-08-23 |
| 163 | Evidence-Based Prospective Study of The Artificial Intelligence Risk Assessment Model for Complication Prevention in Plastic Surgery PF:6 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this observational study is to determine if an AI-based risk assessment model can help prevent complications in plastic surgery patients by improving decision-making, providing recommendations to address risk factors, and assisting doctors in choosing the optimal timing and setting for elective plastic surgery. The study aims to answer if the AI model can effectively identify high-risk patients and what specific risk factors predict complications. Purpose: Evaluate the clinical effectiveness of an AI-based risk assessment model in preventing complications in plastic surgery patients by analyzing clinical data and patient history, … |
WILLIAMS E BUKRET; | 2024-05-31 |
| 164 | Mindfulness Meditation to Improve Patient Satisfaction and Post-operative Outcomes in Rhinoplasty Patients: A Randomized Controlled Trial Related Papers Related Patents Related Grants Related Experts Highlight: A key factor in determining success of facial plastic plastic surgery is overall patient satisfaction. While a number of patient-reported outcomes tools has been developed, there is still limited research in how physicians can improve patient satisfaction and post-operative outcomes. The goal of this study is to investigate the effect of a mindfulness meditation phone application on rhinoplasty outcomes. This study will also explore whether mindfulness meditation is a feasible adjunct to current pharmacological modalities of postoperative pain control as well as its potential impact on patient satisfaction. These questions will be answered using a randomized controlled trial. |
LISA ISHII; | 2022-12-31 |
| 165 | Patient Satisfaction After Medial Fat Pad Preservation in Upper Eyelid Blepharoplasty PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Medial upper eyelid pad of fat bulge is a common problem. medial fat pad preservation might be a good adjutant to upper eyelid blepharoplasty |
TAREK ROSHDY MOHAMED MAHGOUB ELHAMAKY; | 2022-06-01 |
| 166 | Deep Learning on 3D Cellular-resolution Tomogram PF:5 Related Papers Related Patents Related Grants Related Experts Highlight: Skin biopsy is the main method to diagnose skin tumors, skin inflammation, and pigmented diseases. However, biopsy is an invasive method that can cause wounds and scars. Optical coherent tomography (OCT) technology is a fast, non-invasive, non-radioactive, and label-free imaging method. This technology generates real-time images of living tissue by detecting the variations in the refractive indexes of various components in soft tissues. Recently, … |
YU-HUNG WU; | 2022-12-31 |
| 167 | Silicone Taping for The Improvement of Abdominal Donor Site Scars Following Autologous Breast Reconstruction; A Randomized, Prospective Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance. Silicone tape will be added to half of the abdominoplasty incision of patients undergoing abdominally-based breast reconstruction procedures two weeks after their operation. They will be followed up and assessed at specific timepoints to determine whether the silicone improves scar outcomes in these patients. |
JASON WILLIAMS; | 2025-02-18 |
| 168 | Implementing Breast Reconstruction Clinical Decision Support in Diverse Practice Settings PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Breast reconstruction after mastectomy is a highly personal decision. Although it can restore quality of life for many, there are numerous risks associated with the procedure. The risk of complications exceeds that of most elective procedures. In past work, a clinical decision support tool, BREASTChoice, with personalized risk information and patient preferences, … |
MARY POLITI; | 2023-02-01 |
| 169 | Using The Masseteric Nerve for Facial Nerve Reanimation: A Clinical Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The return of eyelid function and facial expression in Patients with facial nerve affection is very important for quality of life. Eyelid dysfunction leads to drying and ulceration of cornea which may lead to permanent vision loss. Facial paralysis is distinguished into two main groups according to the presence or absence of facial fibrillations at needle Electromyography. Recent paralysis, … |
AHMED MOHAMED REFAAT AHMED ABDELKARIM; | 2023-04-01 |
| 170 | Comparison of The Efficacy Between Small Incision Technique and Upper Blepharoplasty in Treatment of Upper Eyelid Medial Pad Fat Bulge PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Medial upper eyelid pad of fat bulge is a common problem. Small incision surgery could be a time-efficient, minimally invasive and scar formation procedure . |
TAREK ROSHDY MOHAMED MAHGOUB ELHAMAKY; | 2021-11-15 |
| 171 | Clinical Assessment of Skin Tightening and Contour Change of Submental Tissue Using Bipolar Radiofrequency Microneedling PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is to evaluate the safety and efficacy of bipolar fractional radiofrequency treatment via use of the Profound System to achieve skin tightening and contour change in lax submental (beneath the chin) tissue. |
JEFFREY M. KENKEL; | 2022-12-22 |
| 172 | Treatment of Complex Perianal Fistulas, in Patients Without Crohn’s Disease, By Endorectal Advancement Flap Associated With Injection of Autologous and Micro-fragmented Adipose Tissue PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The study aims to evaluate effectiveness of the association of endorectal advancement flap technique with local injection of autologous and micro-fragmented adipose tissue, obtained with the Lipogems® system, in patients with complex Perianal Fistulas not related to Crohn’s Disease. |
SALVADOR GUILLAUMES; | 2024-09-01 |
| 173 | Impact of Iron Stores on Wound Healing in Plastic Surgery PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight. A normal healing involve cellular and biochemical reactions in which iron plays an important role such as cellular respiration, redox reactions and regulation of genes involved in the cell cycle. This trial will study the relationship between iron stores and postoperative wound healing after bilateral breast reduction surgery in patients without preoperative anaemia.The primary outcome of this trial is the comparison of wound healing at post operative day 15, … |
ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS | 2020-12-15 |
| 174 | Artificial Eye Blinking Stimulation Following Paralysis of The Facial Nerve PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Artificial eye blinking stimulation following damage to the facial nerve. Group 1 – Patients with a persistent unilateral facial paralysis (palsy) that underwent an operation for facial reanimation Group 2 – Patients with temporary unilateral facial paralysis, secondary to unilateral Bell’s palsy. Primary objective: To evaluate whether the Neurotigger device can elicit a complete or a partial eyelid closure of the affected eye. Secondary objective: To optimize the location of the Neurotrigger’s electrodes, and define the level of the pain generated, if any, during device implementation and stimulation, … |
EYAL GUR; | 2021-12-30 |
| 175 | The Effect of Eyelid Patching After Anterior Lector Reinsertion and Blepharoplasty on Edema, Hematoma, Scar Formation and Ocular Surface Irritation PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery. The main question it aims to answer are: Effect of dressing on edema, hematoma, scar formation, ocular surface irritation and postoperative pain. Patients are randomized after surgery for compression dressing or not. Results are scored by a blinded observer. type of study: clinical trial |
ANNA SCHUH; | 2022-12-01 |
| 176 | Use of Perioperative Ketorolac in Breast Surgery to Reduce Post Operative Pain and Opioid Use PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is to investigate whether perioperative single-dose administration of ketorolac (Toradol) can reduce post-operative pain after breast surgery, thereby decreasing post-operative opioid use. |
JAMES T THOMPSON; | 2023-01-30 |
| 177 | The Effect of Pectoral Blocks on Perioperative Pain in Simple Mastectomy and Breast Reduction in Gender Affirmation Surgery PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Despite recent advancements with regional and local anesthesia, postoperative pain continues to be a major concern for patients undergoing breast surgery. Opioids, often in combination with NSAIDS and/or gabapentioids, have been the main pharmacologic pain control strategy in the postoperative period. The pectoral nerve block is a regional anesthetic technique, which is effective at providing postoperative anesthesia in breast surgeries. However, … |
ESTHER KIM; | 2022-04-30 |
| 178 | A Comparison of The Effect of Suture Material on Blepharoplasty Incision PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture. Additionally, the study will assess whether certain Fitzpatrick skin types are associated with increased rates of poor outcomes after blepharoplasty. |
MICHAEL YOON; | 2024-06-30 |
| 179 | Multiple Gingival Recessions Root Coverage Using Coronally Advanced Tunnel Technique Combined with A Xenogenic Dermal Matrix (Novomatrix®): A Randomized Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: A randomized clinical trial comparing the modified tunnel technique with the use of acellular xenogeneic matrix and connective tissue with the use leucocyte platlet rich fibrin (L-PRF) |
ANDRES PASCUAL LA ROCCA; | 2024-04-28 |
| 180 | Improving Case Selection for Perioperative S. Aureus Transmission Surveillance to Reduce Surgical Site Infections Related Papers Related Patents Related Grants Related Experts Highlight: The first patient in the dyad will receive the bundle, which includes patient decolonization methods, environmental cleaning in the OR, a hand hygiene system located on the IV pole for the anesthesia provider, and intravascular catheter and syringe tip disinfection practices. The second patient in the dyad will receive usual care. Both patients will be surveyed by obtaining swab samples at the beginning and end of the surgery using the OR PathTrac kits. The OR PathTrac software (RDB Bioinformatics, Omaha, … |
RANDY LOFTUS; | 2021-08-01 |
| 181 | Celecoxib Vs. Acetaminophen-codeine-caffeine for Postoperative Pain in Primary Elective Open Septorhinoplasty With Osteotomies: A Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The primary aim of this study is to evaluate whether celecoxib (CELEBREX) is equivalent to acetaminophen-codeine-caffeine (TYLENOL# 3) for the management of pain after primary elective open septorhinoplasty with osteotomies. Secondary objectives include comparison of adverse medication effects and complications (e.g., bleeding events and bruising) that occur postoperatively. Half of the study participants will receive celecoxib, and half will receive acetaminophen-codeine-caffeine. We hypothesize that both interventions will exhibit no difference in pain control or postoperative bleeding, but that participants taking CELEBREX will experience less medication-related side effects and less bruising postoperatively. |
BLAKE RAGGIO; | 2020-12-01 |
| 182 | Comparison of Clinical Outcomes Following Upper Lid Blepharoplasty With and Without Tranexamic Acid As An Additive to Traditional Local Anesthetic PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The goal of this investigation is to assess whether or not there is a significant difference in the presence and/or degree of post-operative ecchymosis, pain, and edema between groups of patients undergoing upper lid blepharoplasty with traditional local anesthetic (LA) and those who receive tranexamic acid (TXA) in addition to traditional LA. |
CRAIG BRAWLEY; | 2023-09-20 |
| 183 | Psychic Stakes of Reconstructive Plastic Surgery in Children With Ear Aplasia PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The objective of the study is to analyse : * Psychic experience of ear aplasia in children ; * the modalities of their psychic functioning ; * and the psychological repercussions of the plastic reconstruction surgery |
FLORA AUBERTIN; | 2026-03-31 |
| 184 | The Effect of Intra-operative Ketorolac on Hematoma Rates in Breast Reduction Surgery: A Double Blind Randomized Control Trial PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: It has been a longstanding teaching in plastic surgery that intra-operative ketorolac use for postoperative pain control increases hematoma and bleeding in breast reduction surgery. However, there is no literature that supports this teaching. Ketorolac is used routinely in free flap reconstruction including breast reconstruction as well as many other surgeries including hand surgery without increased risks of hematoma or bleeding. Ketorolac has been shown to give good postoperative pain control. The object of this study is to look at whether ketorolac increases the rate of hematoma/bleeding in breast reduction. If there is no increased risk of hematoma, … |
GEETHAN CHANDRAN; | 2023-12-31 |
| 185 | Comparative Evaluation of Coronally Advanced Root Coverage Procedure With Ossix Volumax™ Collagen Matrix and Connective Tissue Graft-Randomized Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The present study is a human, prospective, randomised controlled clinical trial conducted to explore the outcome of a coronally advanced flap with ossix volumaxTM collagen matrix and connective tissue graft in the treatment of multiple adjacent gingival recession defects. The trial is in accordance with the Consolidated Standards of Reporting Trials (CONSORT) criteria, 2010. |
KRISHNADEVARAYA COLLEGE OF DENTAL SCIENCES & HOSPITAL | 2021-08-01 |
| 186 | Effects of Capacitive Radiofrequency at The Dermis and Adipose Tissue in The Abdominal Region PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Noninvasive fat reduction is a rapidly expanding field of cosmetic rejuvenation, as many patients are unwilling to suffer the downtime and healing associated with traditional invasive liposuction. The radiofrequency (RF) device has been shown to be safe and effective for non-invasive fat reduction, as well as cutaneous enhancement and improvement of skin flaccidity (BOISNIC, et al., 2014). |
ANDREIA NOITES; | 2020-07-31 |
| 187 | The Ultrasound-guided Multiple-injection Costotransverse Block for Mastectomy and Primary Reconstructive Surgery. A Double Blind, Randomised, Placebo Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The investigators have developed a novel ultrasound-guided nerve block indicated primarily for breast cancer surgery that mimic a thoracic paravertebral block (TPVB) – hitherto the internationally accepted regional anesthesia golden standard for anesthesia of the hemithorax – but hypothetically without the risks of adverse events associated with the TPVB (i.e. pneumothorax, risk of bleeding in the thoracic paravertebral space, random and unmanageable epidural spread etc.). The investigators have already tested the anatomical- and block execution hypothesis in a randomized cadaveric study, … |
ZEALAND UNIVERSITY HOSPITAL | 2021-12-08 |
| 188 | Safety and Efficacy of Combining Thread Lifting With Microfocused Ultrasound for Lifting and Tightening The Face PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Skin aging is a continuous and inevitable presses usually starting at the age of mid-twenties, this prosses affects all facial layers including skin, subcutaneous fat, superficial muscular aponeurotic system (SMAS), deep facia, the retaining ligaments, muscle activity, and even facial bony structure . The clinical outcome of this process causes the aging signs of the face and neck, including loose facial skin, sagging cheeks, excess skin hanging from the lower jawline and excess fat in the neck . In the last decade with the introduction of absorbable threads, thread lifting has gained interest and popularity among patients and physicians, … |
TEL AVIV SOURASKY MEDICAL CENTER | 2021-11-15 |
| 189 | A Pilot Study of REGENERA Implant in Localized Non- Malignant Breast Lesions Treated By Excision or Lumpectomy PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this First-in-Human pilot study is to evaluate the safety and performance of REGENERA breast implant in a selected cohort of patients with non- malignant breast lesions treated with excision or lumpectomy in whom the tissue removed is replaced by REGENERA. |
MANUELA RONCELLA; | 2021-11-27 |
| 190 | A Randomized Prospective Controlled Study Evaluating The Effectiveness of Bilateral Erector Spinae Plane Blocks in Addition to Standard Multimodal Analgesia at Reducing Opioid Consumption in Patients Undergoing Elective Mammoplasty in An Ambulatory Surgical Center PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Study the benefits of a Erector Spinae nerve block for pain control and decrease narcotics usage after mammoplasty in an ambulatory setting |
ELILARY MONTILLA MEDRANO; | 2026-01-29 |
| 191 | Systemic Symptoms: Biospecimen Analysis Study PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: An increasing number of women are reporting a collection of non-specific systemic symptoms thought to be caused by their breast implants. There is no current pathophysiologic explanation or diagnostic test for BII; it is not a recognized medical disease at this time. This study aims to address the questions asked by patients, physicians, and the FDA with regard to the scientific validity of BII. |
CAROLINE GLICKSMAN; | 2025-08-22 |
| 192 | Pivotal Study to Evaluate The Efficacy and Safety of Injection With LASBEAU Strong As Compared to Restylane® Lyft Lidocaine in Temporary Correction of Nasolabial Folds PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Background: Nonsurgical injectable treatments have become popular for aesthetic purposes. In recent years, cross-linked hyaluronic acid (HA) fillers containing lidocaine have been used to correct the nasolabial folds. Aim: The aim of this study was to demonstrate the efficacy and safety of a new HA filler (LASBEAU Strong) (24 mg/mL) compared with a conventional HA filler (Restylane Lyft) for the restoration of nasolabial folds. Patients/methods: A total of 72 subjects were enrolled and randomized to receive injections of the new HA filler (test group) or the conventional HA filler (control group) on the left or right side of the face. The mean value difference in the Wrinkle Severity Rating Scale (WSRS) scores at week 24 evaluated primary efficacy. The WSRS and the Global Aesthetic Improvement Scale (GAIS) at weeks 8, 16, 24, and 48 evaluated secondary efficacy. Adverse events, laboratory tests, and a check of vital signs at every visit assessed safety. |
CHONG HYUN WON; | 2020-11-24 |
| 193 | Prevention of Post-operative Atrial Fibrillation By BOTulinum Toxin Injections Into Epicardial Fat Pads Around Pulmonary Veins in Patients Undergoing Cardiac Surgery PF:3 Related Papers Related Patents Related Grants Related Experts Highlight: Over the past few years, research has focused on the prevention of atrial fibrillation (AF) after cardiac surgery, but highly effective interventions are still missing. Postoperative AF remains the most common complication after cardiac surgery, with an incidence of 10 to 50%. This complication is usually a transient condition that resolves spontaneously but it has major adverse consequences for patients and the health care system, including increased rates of death, complications (strokes), and hospitalisations with inflated costs. Recently, … |
FLORENS EMMANUELLE; | 2025-05-16 |
| 194 | Multi-Polar RF and PEMF Technologies for The Treatment of Vaginal Laxity and for Treatment of The Mons Pubis and Labia for Improvement of Skin Laxity: 12-Month Safety and Efficacy PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Twelve month extension of a previous study of Multi-Polar RF and PEMF technologies for the treatment of vaginal laxity and for the treatment of the mons pubis and labia for improvement in skin laxity. The study will enroll up to 50 subjects who completed the Venus Fiore CS0716 study for the treatment of vaginal laxity and treatment of the mons pubis and labia for improvement in skin laxity. Subjects will be followed up at least six and twelve months post-treatment. Analysis will be performed on all subjects who complete the six-month and twelve month follow-up visits. |
JENNIFER PEARLMAN; | 2022-07-31 |
| 195 | Mechanisms of LPRF Action in The Promotion of Wound Healing and Tissue Regeneration: A Randomised Controlled Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: This study evaluates the clinical and biological effects of leucocyte and platelet-rich fibrin (L-PRF) on intraoral wound healing. |
MAURIZIO TONETTI; | 2022-12-31 |
| 196 | Topical Nitroglycerin As A Mechanism for Cutaneous Vaso-modulation and Improved Wound Healing After Breast Reduction Related Papers Related Patents Related Grants Related Experts Highlight: The purpose of this study is evaluate the effect of Nitroglycerin paste on wound healing and scarring. Previous research has shown that Nitroglycerin paste can improve the blood flow to a wound, which may be associated with better wound healing, and ultimately, better scarring. |
PETER J. TAUB; | 2022-11-01 |
| 197 | The Efficacy and Molecular Mechanism of Botulinum Toxin in The Reduction of Breast Reduction Mammoplasty Scar Formation: A Prospective, Controlled, Randomized, Double-blinded Study PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: 1. Test the ability of botulinum toxin type A, when injected into the surgical incision at the time of surgery, to decrease postoperative scar scores compared to control (normal saline) in a double-blinded randomized control trial. 2. Investigate the mechanism of BTXa effects of scar formation by measuring micro RNA profiles at two time points in the healing process. |
DAVID M. OZOG; | 2023-12-30 |
| 198 | Wide-awake Local Anesthesia and No Tourniquet (WALANT) in Plastic Surgery: Indications, Clinical Applications and Outcomes PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: Wide-awake local anesthesia no tourniquet (WALANT) was proposed and performed in hand operations. Aim of this study is to present the use of WALANT in operations performed on the upper and lower limbs, evaluate its efficacy in terms of feasibility, total operation time, total operating room time, bleeding, patient discomfort and satisfaction and control for potential drawbacks. The hypothesis is that WALANT is a viable option in common operations performed by plastic surgeons on the upper and lower limbs. |
KONSTANTINOS SERETIS; | 2022-07-01 |
| 199 | Clinical and Radiographic Evaluation of Formocresol, Ferric Sulfate and Hyaluronic Acid Pulpotomies on Human Primary Teeth: A Randomized Controlled Clinical Trial PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: In this study, 120 primary molar teeth from healthy children aged between 5 and 9 and who apply to Marmara University Faculty of Dentistry, Department of Pediatric Dentistry will be subjected to pulpotomy treatments. After proper diagnosis of coronal pulpitis, the teeth will be assigned randomly to one of the 3 groups: 40 primary molars for formocresol (FC) pulpotomy treatments, 40 primary molars for ferric sulfate (FS) treatments and 40 primary molars for 0.5% hyaluronic acid gel (HA) pulpotomy treatments. The tooth decay will be removed, … |
ALI MENTES; | 2020-10-01 |
| 200 | Virtual Reality in Plastic Surgery: Pain Control and Augmented Satisfaction PF:2 Related Papers Related Patents Related Grants Related Experts Highlight: The study is looking at whether wearing a virtual reality device will help reduce pain and anxiety during minor procedures |
KARIM W SADIK; | 2020-08-01 |